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  • 23 Sep 2015
  • Research & Ideas

Men Want Powerful Jobs More Than Women Do

New research from Harvard Business School reveals a stark gap in the professional ambitions of men and women. Having surveyed a diverse sample of more than 4,000 men and women, a team of social scientists reports a list of potentially... View Details
Keywords: by Carmen Nobel
  • March, 2023
  • Article

Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes

By: Maria P. Roche
The transfer of complex knowledge and skills is difficult, often requiring intensive interaction and extensive periods of co-working between a mentor and mentee, which is particularly true in apprenticeship-like settings and on-the-job training. This paper studies a... View Details
Keywords: Entrepreneurship; Higher Education; Training; Personal Development and Career; Knowledge Dissemination
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Roche, Maria P. "Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes." Organization Science 34, no. 2 (March, 2023): 959–986.
  • 2023
  • Working Paper

Mapping Organizational-Level Networks Using Individual-Level Connections: Evidence from Online Professional Networks

By: Shelley Xin Li, Frank Nagle and Aner Zhou
Organization-level networks facilitate the flow of information and business activities in the economy. Prior research relies solely on high-level connections to measure these networks. Therefore, to understand the role of employee connections at all job levels in... View Details
Keywords: Networks; Value; Social and Collaborative Networks; Innovation and Invention; Knowledge Sharing; Employees; Social Media
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Li, Shelley Xin, Frank Nagle, and Aner Zhou. "Mapping Organizational-Level Networks Using Individual-Level Connections: Evidence from Online Professional Networks." Harvard Business School Working Paper, No. 24-010, August 2023.
  • Research Summary

Reforming Social Science

By: Max H. Bazerman

Social science research affects all of us. When researchers learned organ donation rates are higher in countries where human organs are automatically available for donation unless you specifically “opt-out” of the system, as opposed to countries like the U.S., where... View Details

  • February 2016
  • Article

Bridging Science and Technology Through Academic-Industry Partnerships

By: Sen Chai and Willy C. Shih
Partnerships that foster the translation of scientific advances emerging from academic research organizations into commercialized products at private firms are a policy tool that has attracted increased interest. This paper examines empirical data from the Danish... View Details
Keywords: Economic Development; Technological Change; Government Policy; Technological Innovation; Research and Development; Information Technology; Policy; Technology Industry; Denmark
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Chai, Sen, and Willy C. Shih. "Bridging Science and Technology Through Academic-Industry Partnerships." Research Policy 45, no. 1 (February 2016): 148–158.
  • May 2025 (Revised June 2025)
  • Case

Daiichi Sankyo: Steering a Global Organization

By: Tiona Zuzul, Amy C. Edmondson and Cat Huang
In the spring of 2023, Sunao Manabe, CEO of Daiichi Sankyo, reflected on a pivotal decision. A large Western pharmaceutical company had made a bid to partner with Daiichi Sankyo to develop the next three products in its oncology pipeline. Daiichi Sankyo, a 125-year old... View Details
Keywords: Strategy; Culture Change; Decision-making; Leadership; Culture; Innovation; Psychological Safety
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Zuzul, Tiona, Amy C. Edmondson, and Cat Huang. "Daiichi Sankyo: Steering a Global Organization." Harvard Business School Case 725-478, May 2025. (Revised June 2025.)
  • 2025
  • Working Paper

Productivity Beliefs and Efficiency in Science

By: Fabio Bertolotti, Kyle R. Myers and Wei Yang Tham
We develop a method to estimate producers’ productivity beliefs in settings where output quantities and input prices are unobservable, and we use it to evaluate allocative efficiency in the market for science. Our model of researchers’ labor supply shows that their... View Details
Keywords: Performance Productivity; Perception; Research
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Bertolotti, Fabio, Kyle R. Myers, and Wei Yang Tham. "Productivity Beliefs and Efficiency in Science." Harvard Business School Working Paper, No. 25-063, June 2025.
  • 03 Jan 2017
  • First Look

January 3, 2017

Winter 2017 MIT Sloan Management Review Why Big Data Isn't Enough By: Chai, Sen, and Willy C. Shih Abstract—There is a growing belief that sophisticated algorithms can explore huge databases and find relationships independent of any preconceived hypotheses. But in... View Details
Keywords: Carmen Nobel
  • November 2014
  • Teaching Note

Claritas Genomics

By: Robert F. Higgins and Matthew G. Preble
Dr. Patrice Milos is the first CEO of Claritas Genomics (Claritas) and she faces a number of challenges in scaling the young company. Claritas was formed around a lab spun out from Boston Children's Hospital (BCH) which had performed genomic tests for the hospital. Now... View Details
Keywords: Healthcare; Healthcare Startups; Genetic Testing; Genetics Diagnostics; Spinning Out Hospital Services; Spin-out; Health Care and Treatment; Genetics; Entrepreneurship; Biotechnology Industry; Health Industry; United States
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Higgins, Robert F., and Matthew G. Preble. "Claritas Genomics." Harvard Business School Teaching Note 815-032, November 2014.
  • Research Summary

The Business of Stem Cells

By: Debora L. Spar
In 2004, the topic of stem cell research made both medical and moral headlines. Buoyed by a series of technological breakthroughs, stem cell scientists grew increasingly convinced that they would eventually be able to use embryonic stem cells -- the pluripotent cells... View Details
  • October 2016 (Revised September 2017)
  • Case

The CRISPR-Cas9 Quarrel

By: Richard G. Hamermesh and Matthew G. Preble
In mid-2016, the Broad Institute and the University of California, Berkeley were in the middle of a contentious patent dispute over which entity controlled a breakthrough gene editing technology called CRISPR-Cas9. With CRISPR-Cas9, scientists might soon be able to... View Details
Keywords: CRISPR; Broad Institute; University Of California Berkeley; Intellectual Property; Patents; Law; Lawsuits and Litigation; Science; Genetics; Entrepreneurship; Biotechnology Industry; United States
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Hamermesh, Richard G., and Matthew G. Preble. "The CRISPR-Cas9 Quarrel." Harvard Business School Case 817-020, October 2016. (Revised September 2017.)
  • 14 Jan 2020
  • Research & Ideas

The Business Case for Becoming a Jack-of-All-Trades

handheld controller. Scientific researchers soon realized the potential for the knowledge embedded in the technology in a whole range of applications, and quickly wrote their own software code to use it. “It... View Details
Keywords: by Michael Blanding
  • 31 Aug 2020
  • What Do You Think?

Why Don’t More Organizations Understand the Power of Diversity and Inclusion?

number of readers put forward well-tempered comments questioning research on whether diversity and inclusion enhance organization performance. The implication is that this may account in some part for the slow pace of progress on this... View Details
Keywords: by James Heskett
  • April 12, 2022
  • Article

Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States

By: Estee Y. Cramer, Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li and et al.
Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models... View Details
Keywords: COVID-19; Forecasting and Prediction; Health Pandemics; Mathematical Methods; Partners and Partnerships
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Cramer, Estee Y., Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li, and et al. "Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States." e2113561119. Proceedings of the National Academy of Sciences 119, no. 15 (April 12, 2022). (See full author list here.)
  • 2019
  • Working Paper

Using Technology to Augment Professionals, Instead of Replacing Them, for Innovative Problem Solving

By: Hila Lifshitz - Assaf, Felicia Ng, Aniket Kittur and Robert Kraut
While in some technological and scientific areas innovation is flourishing, in others it is stalling, leaving important problems unsolved for decades. One explanation is professionals’ limitations as problem solvers, as accumulating depth of knowledge enhances one’s... View Details
Keywords: Innovation; Expertise; Future Of Work; Crowdsourcing; Artificial Intelligence; Problem Solving; Professionalism; Experience and Expertise; Collaborative Innovation and Invention; Problems and Challenges; Research and Development
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Lifshitz - Assaf, Hila, Felicia Ng, Aniket Kittur, and Robert Kraut. "Using Technology to Augment Professionals, Instead of Replacing Them, for Innovative Problem Solving." Working Paper, March 2019.
  • 04 Jul 2005
  • What Do You Think?

How Can Business Schools Be Made More Relevant?

specific knowledge," and emphasis on "more variables [that] enter into people's choices than just value maximizing." Don Cameron thinks that "The problem with research is not the research... View Details
Keywords: by James Heskett
  • 11 Sep 2012
  • First Look

First Look: September 11

decreases the compassion that individuals express to others in need, that this effect is mediated by dampened feelings of empathy and heightened perceptions of unprofessionalism, and that it is circumscribed to bad news that has economic implications. We discuss... View Details
Keywords: Sean Silverthorne
  • Article

The Evolution of Science-Based Business: Innovating How We Innovate

By: Gary P. Pisano
Science has long been connected to innovation and to business. As early as the late 19th century, chemical companies, realizing the commercial potential of science, created the first industrial research laboratories. During much of the 20th century, large-scale... View Details
Keywords: Entrepreneurship; Governance; Innovation and Management; Risk Management; Research and Development; Science-Based Business; Commercialization
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Pisano, Gary P. "The Evolution of Science-Based Business: Innovating How We Innovate." Special Issue on Management Innovation—Essays in the Spirit of Alfred D. Chandler. Industrial and Corporate Change 19, no. 2 (April 2010): 465–482.
  • 12 Apr 2007
  • Working Paper Summaries

From Manufacturing to Design: An Essay on the Work of Kim B. Clark

Keywords: by Sylvain Lenfle & Carliss Y. Baldwin; Manufacturing
  • Article

Marginality and Problem-Solving Effectiveness in Broadcast Search

By: Lars Bo Jeppesen and Karim R. Lakhani
We examine who the winners are in science problem-solving contests characterized by open broadcast of problem information, self-selection of external solvers to discrete problems from the laboratories of large R&D intensive companies, and blind review of solution... View Details
Keywords: Competition; Open Source Distribution; Knowledge Use and Leverage; Markets; Independent Innovation and Invention; Problems and Challenges; Research and Development; Gender; Science
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Jeppesen, Lars Bo, and Karim R. Lakhani. "Marginality and Problem-Solving Effectiveness in Broadcast Search." Organization Science 21, no. 5 (September–October 2010): 1016–1033.
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