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- All HBS Web (215)
- Faculty Publications (146)
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- February 2014
- Case
BGI: Data-driven Research
By: Willy Shih and Sen Chai
BGI has the largest installed gene-sequencing capacity in the world, and to Zhang Gengyun, general manager of the Life Sciences Division, this represented an opportunity to apply his training as a plant breeder and his early career work as a biochemist to improving... View Details
Keywords: Genomics; Gene Sequencing; Life Sciences; Plant Breeding; Human Genome Program; Beijing Genomics Institute; BGI; Rice Genome; Technological Innovation; Innovation Strategy; Research; Research and Development; Science; Genetics; Science-Based Business; Strategy; Commercialization; Corporate Strategy; Information Technology; Applications and Software; Agriculture and Agribusiness Industry; Biotechnology Industry; Food and Beverage Industry; China; United States
Shih, Willy, and Sen Chai. "BGI: Data-driven Research." Harvard Business School Case 614-056, February 2014.
- August 1991 (Revised March 1993)
- Case
Champion International Corp.: Timber, Trade, and the Northern Spotted Owl
Champion's forest products division owns timberlands, sawmills, and plywood mills in the Pacific Northwest. The listing of the northern spotted owl as an endangered species, and restrictions on exports of logs from state-owned lands, have disrupted the stumpage, log... View Details
Keywords: Science-Based Business; Natural Environment; Product Marketing; Governing Rules, Regulations, and Reforms; Government and Politics; Environmental Sustainability; Corporate Strategy; Trade; Decisions; Management Teams; Forest Products Industry; North and Central America
Reinhardt, Forest L. "Champion International Corp.: Timber, Trade, and the Northern Spotted Owl." Harvard Business School Case 792-017, August 1991. (Revised March 1993.)
- January 2013 (Revised September 2013)
- Case
Royal DSM: Fighting Hidden Hunger
By: Rebecca Henderson, Noah Fisher and Mary Shelman
In 2007 Royal DSM, a leading life science and materials company, entered a partnership with the World Food Programme (WFP) to combat hidden hunger around the world by providing micronutrient solutions. The case investigates the unexpectedly large impact the partnership... View Details
Keywords: Conflict of Interests; Human Needs; Partners and Partnerships; Global Range; Nutrition; Science-Based Business; Non-Governmental Organizations; Service Industry; Health Industry
Henderson, Rebecca, Noah Fisher, and Mary Shelman. "Royal DSM: Fighting Hidden Hunger." Harvard Business School Case 313-085, January 2013. (Revised September 2013.)
- November 2012
- Case
CSIRO: The Light Metals Flagship Decision
By: Willy Shih, Margaret P. Pierson and Dawn Lau
This case explores the challenge of investing in basic research as a public good. CSIRO was Australia's leading science and research agency, and it was chartered to enhance national prosperity through R&D. Its Flagships program was designed to align research interests... View Details
Keywords: R＆D; Basic Research; Government-funded Research; Public Goods; Extractive Industries; Metals; Metals Processing; Decision Choices and Conditions; Decisions; Globalized Markets and Industries; Growth and Development; Innovation Strategy; Technological Innovation; Research and Development; Science-Based Business; Technology Adoption; Technology Platform; Manufacturing Industry; Mining Industry; Oceania; Australia
Shih, Willy, Margaret P. Pierson, and Dawn Lau. "CSIRO: The Light Metals Flagship Decision." Harvard Business School Case 613-029, November 2012.
- 12 Oct 2006
- First Look
First Look: October 12, 2006
prescriptions for companies, investors, and policymakers seeking ways to improve the industry's performance. According to Pisano, the biotech industry's problems stem from its special character as a science-based business. This character... View Details
Keywords: Sean Silverthorne
- May 2025
- Supplement
Michael Ku and Global Clinical Supply at Pfizer Inc.: Bringing Hope to Patients (D)
By: Linda A. Hill and Lydia Begag
This fourth installment in the Pfizer Global Clinical Supply (GCS) transformation case series highlights how over a decade of cultural and digital evolution positioned GCS to meet unprecedented global challenges. In 2011, Michael Ku became the Vice President of GCS and... View Details
- 17 Jul 2012
- First Look
First Look: July 17
Science-Based Business (Abridged) Ananth Raman and Inga MaurerHarvard Business School Case 611-027 Ray Gilmartin faces a dilemma. His company's credibility has been damaged by... View Details
Keywords: Sean Silverthorne
- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
Keywords: Working Capital; Financing and Loans; Health Testing and Trials; Product Development; Research and Development; Science-Based Business; Commercialization; Biotechnology Industry; Pharmaceutical Industry
Gompers, Paul A., Elie Ofek, Orna Dan, and Emilie Billaud. "BiomX: Bringing Phage Back to the Stage." Harvard Business School Case 524-051, November 2023. (Revised April 2024.)
- July 1997 (Revised June 2001)
- Case
H.E. Butt Grocery Company: A Leader in ECR Implementation (B) (Abridged)
By: Robert D. Austin and F. Warren McFarlan
H.E. Butt Grocery Co. led the grocery industry in adopting many innovations, including category management, electronic data interchange, and continuous replenishment. They have also moved aggressively and profitably into newer applications such as Scanner-based payment... View Details
Keywords: Information Management; Independent Innovation and Invention; Innovation and Invention; Business Organization; Risk and Uncertainty; Science-Based Business; Cross-Cultural and Cross-Border Issues; Management Analysis, Tools, and Techniques; Risk Management; Electronics Industry; Computer Industry
Austin, Robert D., and F. Warren McFarlan. "H.E. Butt Grocery Company: A Leader in ECR Implementation (B) (Abridged)." Harvard Business School Case 198-016, July 1997. (Revised June 2001.)
- July 2011 (Revised January 2013)
- Case
Digital Microscopy Is Making Me Crazy!
By: Willy Shih
For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical... View Details
Keywords: Information Infrastructure; Applications and Software; Corporate Strategy; Disruptive Innovation; Science-Based Business; Management Analysis, Tools, and Techniques; Business Conglomerates; Digital Platforms; Opportunities; Medical Devices and Supplies Industry; Computer Industry
Shih, Willy. "Digital Microscopy Is Making Me Crazy!" Harvard Business School Case 612-002, July 2011. (Revised January 2013.)
- 15 Oct 2013
- First Look
First Look: October 15
designated partners within the larger fluid department. Our multi-method study reveals the design and benefit of minimal team structures (team scaffolds) in fluid work settings. Download working paper: http://ssrn.com/abstract=1987724 Cases & Course Materials... View Details
Keywords: Sean Silverthorne
- February 2024 (Revised March 2024)
- Teaching Note
X: The Foghorn Decision
By: Kyle Myers and Walter Frick
Teaching Note for HBS Case No. 618-060. View Details
Keywords: Alternative Energy; Energy Generation; Energy Sources; Climate Change; Green Technology; Selection and Staffing; Knowledge; Product Design; Product Development; Research and Development; Risk and Uncertainty; Science-Based Business; Innovation and Invention; Auto Industry; Biotechnology Industry; Chemical Industry; Computer Industry; Electronics Industry; Green Technology Industry; Technology Industry
- 28 Feb 2019
- Cold Call Podcast
Pursuing Precision Medicine at Intermountain Healthcare
- October 2019 (Revised December 2019)
- Supplement
Extend Fertility: Conceiving the Market for Egg Preservation (B)
By: Debora L. Spar and Olivia Hull
Keywords: Strategy; Information Technology; Business Startups; Entrepreneurship; Innovation Strategy; Technological Innovation; Commercialization; Science-Based Business; Marketing Strategy; Business Plan; Product Marketing; Product Launch; Product Positioning; Mission and Purpose; Personal Development and Career; Social Issues; Integration; Health; Health Industry
Spar, Debora L., and Olivia Hull. "Extend Fertility: Conceiving the Market for Egg Preservation (B)." Harvard Business School Supplement 720-017, October 2019. (Revised December 2019.)
- January 2024
- Case
Fusion Industry Association: Igniting the Future of Clean Energy
Fusion energy is evolving from a scientific idea to a commercial possibility, drawing large investments and regulatory discussions; how should the FIA navigate this evolution?
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
The Fusion Industry Association (FIA) is at the forefront of transforming fusion... View Details
Keywords: Science-Based Business; Engineering; Venture Capital; Entrepreneurship; Government and Politics; Government Legislation; Industry Clusters; Industry Growth; Industry Structures; Technological Innovation; Energy Industry; United States
Krieger, Joshua Lev, Jim Matheson, Kyle R. Myers, and Henry Tao. "Fusion Industry Association: Igniting the Future of Clean Energy." Harvard Business School Case 624-064, January 2024.
- August 2023 (Revised January 2024)
- Supplement
Arla Foods: Data-Driven Decarbonization (A)
By: Michael Parzen, Michael W. Toffel, Amram Migdal and Susan Pinckney
Arla implemented a data-based price incentive system to measure, track, and influence climate friendly changes to reduce CO2 emissions across the world’s fourth largest dairy cooperative. View Details
Keywords: Dairy Industry; Business Earnings; Earnings Management; Environmental Accounting; Agribusiness; Animal-Based Agribusiness; Acquisition; Mergers and Acquisitions; Decision Making; Decisions; Voting; Environmental Management; Climate Change; Environmental Regulation; Environmental Sustainability; Green Technology; Pollution; Moral Sensibility; Values and Beliefs; Financial Strategy; Price; Profit; Revenue; Food; Geopolitical Units; Global Strategy; Ownership Type; Cooperative Ownership; Performance Efficiency; Performance Evaluation; Problems and Challenges; Natural Environment; Science-Based Business; Business Strategy; Commercialization; Cooperation; Corporate Strategy; Food and Beverage Industry; Agriculture and Agribusiness Industry; Europe; United Kingdom; European Union; Germany; Denmark; Sweden; Luxembourg; Belgium
- April 2024 (Revised November 2024)
- Case
Moderna: Pioneering a People Platform to Accelerate Science Innovation
By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Biotechnology Industry; United States
Sandino, Tatiana, Emil Dy, and Samuel Grad. "Moderna: Pioneering a People Platform to Accelerate Science Innovation." Harvard Business School Case 124-091, April 2024. (Revised November 2024.)
- 30 May 2005
- Research & Ideas
Germany’s Pioneering Corporate Managers
by such great managers as August Thyssen, Alfred Krupp, and Werner Siemens. Professor Jeffrey Fear's book Organizing Control: August Thyssen and the Construction of German Corporate Management overturns some of our preconceptions of German View Details
Keywords: by Sean Silverthorne
- Research Summary
Overview
By: Kyle R. Myers
Professor Myers studies the economics of what determines the rate and direction of innovation. He has examined the reallocation of scientists through the use of targeted research grants at the National Institutes of Health, and is working to further understand how... View Details
Keywords: Technology Networks; Commercialization; Science-Based Business; Research and Development; Knowledge Management; Patents; Innovation Strategy; Technological Innovation; Health Care and Treatment; Entrepreneurship; Health; Innovation and Invention; Science; Technology; Knowledge; Intellectual Property; Economics; Microeconomics; Biotechnology Industry; Health Industry; Pharmaceutical Industry; Technology Industry
- August 2023 (Revised January 2024)
- Supplement
Arla Foods: Data-Driven Decarbonization (B)
By: Michael Parzen, Michael W. Toffel, Susan Pinckney and Amram Migdal
The case describes Arla’s history, in particular its climate change mitigation efforts, and how it implemented a price incentive system to motivate individual farms to implement scope 1 greenhouse gas emissions mitigation measures and receive a higher milk price. The... View Details
Keywords: Dairy Industry; Earnings Management; Environmental Accounting; Animal-Based Agribusiness; Mergers and Acquisitions; Decisions; Voting; Climate Change; Environmental Regulation; Environmental Sustainability; Green Technology; Pollution; Moral Sensibility; Values and Beliefs; Financial Strategy; Price; Profit; Revenue; Food; Geopolitical Units; Cross-Cultural and Cross-Border Issues; Global Strategy; Cooperative Ownership; Performance Efficiency; Performance Evaluation; Problems and Challenges; Natural Environment; Science-Based Business; Business Strategy; Commercial Banking; Cooperation; Corporate Strategy; Motivation and Incentives; Food and Beverage Industry; Agriculture and Agribusiness Industry; Europe; United Kingdom; European Union; Denmark; Sweden; Luxembourg; Belgium
Parzen, Michael, Michael W. Toffel, Susan Pinckney, and Amram Migdal. "Arla Foods: Data-Driven Decarbonization (B)." Harvard Business School Supplement 624-036, August 2023. (Revised January 2024.)