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      • October 2019 (Revised April 2020)
      • Background Note

      Note on Funding Deep Tech Startups

      By: Karim Lakhani, Peter Barrett and Noubar Afeyan
      This Background Note provides essential information on funding deep technologies—those technologies that were inherently capital intensive, time consuming, risky, and potentially disruptive. Both dilutive and non-dilutive sources of investment are highlighted, along... View Details
      Keywords: Entrepreneurship; Energy; Venture Capital; Corporate Finance; Initial Public Offering; Investment; Health Testing and Trials; Innovation and Invention; Technological Innovation; Intellectual Property; Product Design; Product Development; Information Technology; Research and Development; Risk and Uncertainty; Technology Industry; Biotechnology Industry; United States; North America; Europe; Asia
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      Lakhani, Karim, Peter Barrett, and Noubar Afeyan. "Note on Funding Deep Tech Startups." Harvard Business School Background Note 620-029, October 2019. (Revised April 2020.)
      • October 10, 2019
      • Article

      The Case for the Public Option Over Medicare for All

      By: Regina E. Herzlinger and Richard Boxer
      How can the United States better control its health care costs and quality and still achieve universal coverage? The strongest choice is not Medicare for All, which would eliminate private insurance; it’s the public option, which would allow people to choose from... View Details
      Keywords: Universal Health Coverage; Public Option; Medicare; Health Care and Treatment; Insurance; Cost Management; Quality; United States
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      Herzlinger, Regina E., and Richard Boxer. "The Case for the Public Option Over Medicare for All." Harvard Business Review Digital Articles (October 10, 2019): 2–5.
      • September 2019
      • Case

      Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem

      By: Willy C. Shih
      Vaccines for children has been a long-standing focus for the Bill & Melinda Gates Foundation, and its critical role in public health made its production an important economic and political issue. This case describes the Foundation's investment in a breakthrough vaccine... View Details
      Keywords: Vaccine; Production; Supply Chain; Product; Biotechnology Industry; Pharmaceutical Industry; Manufacturing Industry; Belgium
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      Shih, Willy C. "Bill & Melinda Gates Foundation: Shaping the Vaccine Manufacturing Ecosystem." Harvard Business School Case 620-021, September 2019.
      • 2024
      • Working Paper

      HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-007, July 2019. (Revised May 2024.)
      • 2022
      • Working Paper

      The Lifesaving Benefits of Convenient Infrastructure: Quantifying the Mortality Impact of Abandoning Shallow Tubewells Contaminated by Arsenic in Bangladesh

      By: Nina Buchmann, Erica Field, Rachel Glennerster and Reshmaan Hussam
      We document the consequences of a public health campaign which led to the sudden abandonment of local water infrastructure by one-fifth of Bangladesh’s population. Households who experienced quasi-randomly distributed arsenic contamination, and thus were likely to... View Details
      Keywords: Child Mortality; Arsenic; Unintended Consequences; Health Disorders; Safety; Outcome or Result; Bangladesh
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      Buchmann, Nina, Erica Field, Rachel Glennerster, and Reshmaan Hussam. "The Lifesaving Benefits of Convenient Infrastructure: Quantifying the Mortality Impact of Abandoning Shallow Tubewells Contaminated by Arsenic in Bangladesh." Working Paper, September 2022.
      • Article

      Health as a Way of Doing Business

      By: Howard Koh, Sara J. Singer and Amy C. Edmondson
      For too long, the worlds of business and health have been mired in a checkered, sometimes contentious, history. Millions of deaths worldwide can be attributed to risk factors including tobacco use, alcohol and drug misuse, and suboptimal dietary intake linked to... View Details
      Keywords: Health; Corporate Social Responsibility and Impact; Public Opinion
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      Koh, Howard, Sara J. Singer, and Amy C. Edmondson. "Health as a Way of Doing Business." JAMA, the Journal of the American Medical Association 321, no. 1 (January 1, 2019): 33–34.
      • Article

      Operational Efficiency and Effective Management in the Catheterization Laboratory

      By: Grant W. Reed, Michael L. Tushman and Samir R. Kapadia
      Operational efficiency is a core business principle in which organizations strive to deliver high-quality goods or services in a cost-effective manner. This concept has become increasingly relevant to cardiac catheterization laboratories, as insurers move away from... View Details
      Keywords: Cath Lab; Catheterization Laboratory; Health Care and Treatment; Performance Efficiency; Management; Performance Productivity; Cost Management; Health Industry
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      Reed, Grant W., Michael L. Tushman, and Samir R. Kapadia. "Operational Efficiency and Effective Management in the Catheterization Laboratory." Journal of the American College of Cardiology 72, no. 20 (November 20, 2018): 2507–2517.
      • October 2018 (Revised September 2020)
      • Case

      Testing Autonomy in Pittsburgh

      By: Mitchell Weiss and Brittany Urick
      Pittsburgh’s mayor had been among the first to welcome self-driving vehicles but was now one of many needing to react after a pedestrian fatality involving an autonomous Uber in Arizona. He had originally preferred to roll out “the red carpet” instead of the “red... View Details
      Keywords: Public Entrepreneurship; Government Innovation; Government Experimentation; Autonomous Vehicles; Mayor; Mayor Peduto; Cities; Mobility; Automation; Uber; Argo Ai; Aurora Innovation; Aptiv; Entrepreneurship; Public Sector; Innovation and Invention; Transportation; City; Safety; Business and Government Relations; Transportation Industry; Auto Industry; United States; Pennsylvania; Pittsburgh
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      Weiss, Mitchell, and Brittany Urick. "Testing Autonomy in Pittsburgh." Harvard Business School Case 819-059, October 2018. (Revised September 2020.)
      • 2018
      • Working Paper

      Sustainability and Green Business in Latin America During Globalization Waves

      By: Geoffrey Jones
      This working paper examines the impact of modern business enterprise on the natural environment of Latin America during the globalization waves between the 19th century and the present day. It argues that although global capitalism created much wealth for the region,... View Details
      Keywords: Globalization; Natural Environment; Outcome or Result; Business History; Pollutants; Environmental Sustainability; Green Technology Industry; Beauty and Cosmetics Industry; Tourism Industry; Latin America
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      Jones, Geoffrey. "Sustainability and Green Business in Latin America During Globalization Waves." Harvard Business School Working Paper, No. 19-009, August 2018.
      • August 2018
      • Article

      The Effect of Graphic Warnings on Sugary-Drink Purchasing

      By: Grant Donnelly, Laura Y. Zatz, Daniel Svirsky and Leslie John
      Governments have proposed text warning labels to decrease consumption of sugary drinks – a contributor to chronic diseases like diabetes. However, they may be less effective than more evocative, graphic warning labels. We field-tested the effectiveness of graphic... View Details
      Keywords: Policy Making; Preferences; Food; Health; Policy; Information; Labels; Consumer Behavior; Decision Making; Performance Effectiveness
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      Donnelly, Grant, Laura Y. Zatz, Daniel Svirsky, and Leslie John. "The Effect of Graphic Warnings on Sugary-Drink Purchasing." Psychological Science 29, no. 8 (August 2018): 1321–1333.
      • 2018
      • Book

      Food Citizenship: Food System Advocates in an Era of Distrust

      By: Ray A. Goldberg
      The global food system is the largest segment of the world's economy. As agribusiness-studies pioneer Ray Goldberg suggests, it is also the largest health system on the planet. And it is changing fast. Its size and importance to human, environmental, and economic... View Details
      Keywords: Food; System; Global Range; Health; Environmental Sustainability; Development Economics; Partners and Partnerships; Public Opinion; Agriculture and Agribusiness Industry; Food and Beverage Industry
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      Goldberg, Ray A. Food Citizenship: Food System Advocates in an Era of Distrust. New York: Oxford University Press, 2018.
      • July 2018
      • Article

      Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India

      By: Satchit Balsari, Alexander Fortenko MD, MPH, Joaquin A. Blaya PhD, Adrian Gropper MD, Malavika Jayaram LLM, Rahul Matthan LLM, Ram Sahasranam, Mark Shankar MD, Suptendra N. Sarbadhikari PhD, Barbara Bierer, Kenneth D. Mandl MD, Sanjay Mehendale MD, MPH and Tarun Khanna
      In February 2018, the Government of India announced a massive public health insurance scheme extending coverage to 500 million citizens, in effect making it the world’s largest insurance program. To meet this target, the government will rely on technology to... View Details
      Keywords: Health Information Exchange; India; Health APIs; Health Care and Treatment; Information; Analytics and Data Science; Information Technology; Health Industry; India
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      Balsari, Satchit, Alexander Fortenko MD, MPH, Joaquin A. Blaya PhD, Adrian Gropper MD, Malavika Jayaram LLM, Rahul Matthan LLM, Ram Sahasranam, Mark Shankar MD, Suptendra N. Sarbadhikari PhD, Barbara Bierer, Kenneth D. Mandl MD, Sanjay Mehendale MD, MPH, and Tarun Khanna. "Reimagining Health Data Exchange: An Application Programming Interface-Enabled Roadmap for India." Journal of Medical Internet Research 20, no. 7 (July 2018).
      • July–August 2018
      • Article

      When Technology Gets Ahead of Society

      By: Tarun Khanna
      New technologies can be unsettling for industry incumbents, regulators, and consumers, because norms and institutions for dealing with them don’t yet exist. Interestingly, businesspeople in emerging economies face similar challenges: The rules are unclear and... View Details
      Keywords: Technological Innovation; Society; Situation or Environment; Infrastructure; Entrepreneurship; Performance Effectiveness; Cooperation
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      Khanna, Tarun. "When Technology Gets Ahead of Society." Harvard Business Review 96, no. 4 (July–August 2018): 86–95.
      • May 2018 (Revised October 2020)
      • Supplement

      La Ribera Health Department (B): Epilogue

      By: Regina E. Herzlinger, Emer Moloney and Daniela Beyersdorfer
      The La Ribera case studies depict an innovative low cost/high quality privately financed hospital model struggling to achieve alignment with the Six Factors. It is reimbursed by the public sector in a Spanish environment whose Consumers, Structure, and Public Policy... View Details
      Keywords: Trends And Opportunities; Government; Government Programs; Acquisition; Business Model; Business Plan; Trends; Opportunities; Government and Politics; Programs; Health Care and Treatment; Situation or Environment; Health Industry; Health Industry; Health Industry; Spain
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      Herzlinger, Regina E., Emer Moloney, and Daniela Beyersdorfer. "La Ribera Health Department (B): Epilogue." Harvard Business School Supplement 318-134, May 2018. (Revised October 2020.)
      • March 2018
      • Supplement

      Improving Access at VA

      By: Ryan W. Buell and Robert S. Huckman
      In 2015, the Department of Veterans Affairs (VA) ran the largest healthcare system in the United States, with over 1,700 sites of care that served nearly 9 million veterans. One year earlier, a scandal had erupted over a cover-up of the excessive wait times veterans... View Details
      Keywords: Service Operations; Service Delivery; Social Issues; Health Care and Treatment; Government Administration; Performance Improvement; Public Administration Industry; Public Administration Industry; United States
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      Buell, Ryan W., and Robert S. Huckman. "Improving Access at VA." Harvard Business School Multimedia/Video Supplement 618-709, March 2018.
      • March 2018 (Revised February 2020)
      • Teaching Note

      Improving Access at VA

      By: Ryan W. Buell and Robert S. Huckman
      In 2015, the Department of Veterans Affairs (VA) ran the largest healthcare system in the United States, with over 1,700 sites of care that served nearly 9 million veterans. One year earlier, a scandal had erupted over a cover-up of the excessive wait times veterans... View Details
      Keywords: Service Operations; Service Delivery; Social Issues; Health Care and Treatment; Government Administration; Performance Improvement; Public Administration Industry; Public Administration Industry; United States
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      Buell, Ryan W., and Robert S. Huckman. "Improving Access at VA." Harvard Business School Teaching Note 618-052, March 2018. (Revised February 2020.)
      • 2020
      • Working Paper

      The Impact of CEOs in the Public Sector: Evidence from the English NHS

      By: Katharina Janke, Carol Propper and Raffaella Sadun
      Abstract Governments worldwide have sought to reform the delivery of public services by mimicking private sector governance models that grant CEOs greater autonomy and give them responsibility for meeting key government targets. We examine the effectiveness of this... View Details
      Keywords: CEOs; Management; Performance; Public Sector; Measurement and Metrics; Health Industry
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      Janke, Katharina, Carol Propper, and Raffaella Sadun. "The Impact of CEOs in the Public Sector: Evidence from the English NHS." Harvard Business School Working Paper, No. 18-075, March 2018. (Revised September 2020.)
      • March 2018 (Revised January 2019)
      • Case

      Gilead Mexico

      By: Michael Chu and V. Kasturi Rangan
      With a breakthrough cure for Hepatitis C listing in the U.S. at $1,000/pill, Gilead must now solve the issue of making it available to patients across the world, much as it did for its blockbuster HIV/AIDS antiretrovirals. For Erik Musalem, the new general manager of... View Details
      Keywords: Health Care and Treatment; Price; Strategy; Management; Pharmaceutical Industry; Mexico
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      Chu, Michael, and V. Kasturi Rangan. "Gilead Mexico." Harvard Business School Case 318-111, March 2018. (Revised January 2019.)
      • 2018
      • Government Testimony

      Health Care Industry Consolidation: What Is Happening, Why It Matters, and What Public Agencies Might Want to Do About It

      By: Leemore S. Dafny
      Keywords: Consolidation; Mergers And Acquisitions; Federal Testimony
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      Dafny, Leemore S. "Health Care Industry Consolidation: What Is Happening, Why It Matters, and What Public Agencies Might Want to Do About It." Government Testimony, U.S. House of Representatives, Committee on Energy and Commerce, Subcommittee on Oversight and Investigations, Washington, DC, February 2018.
      • January 2018 (Revised March 2018)
      • Case

      Wenzhou Kangning Hospital: Changing Mental Healthcare in China

      By: William C. Kirby, Wei Zhang, Yuanzhuo Wang and Nancy Hua Dai
      The city of Wenzhou in the Province of Zhejiang, long known in China for entrepreneurship, now hosts the country’s largest privately owned mental health hospital group. This case traces the development of Wenzhou Kangning Hospital Co, Ltd. from founding to just before... View Details
      Keywords: Mental Health; Hospital; IPO; China; Zhejiang; Wenzhou; Private Healthcare; Private Hospital; Health Care and Treatment; Private Ownership; Corporate Governance; Growth and Development; Entrepreneurship; Health Industry; China
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      Kirby, William C., Wei Zhang, Yuanzhuo Wang, and Nancy Hua Dai. "Wenzhou Kangning Hospital: Changing Mental Healthcare in China." Harvard Business School Case 318-054, January 2018. (Revised March 2018.)
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