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  • November 2021 (Revised December 2024)
  • Case

Kermit PPI

By: Kyle Myers, Matt Grennan and Sarah Mehta
Launched in 2011, Kermit PPI helped hospitals save money on expensive orthopedic implants and devices by enabling them to renegotiate their contracts with device manufacturers and better monitor compliance. In 2021, as they look to grow, they are entertaining two... View Details
Keywords: Health; Health Care and Treatment; Strategy; Expansion; Information Technology; Applications and Software; Supply Chain; Supply Chain Management; Contracts; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States; Maryland
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Myers, Kyle, Matt Grennan, and Sarah Mehta. "Kermit PPI." Harvard Business School Case 622-007, November 2021. (Revised December 2024.)
  • February 2025
  • Case

Abiomed: A Change of Heart

By: Satish Tadikonda, Faith Robertson and William Marks
After acquiring Impella CardioSystems AG in May 2005, Abiomed Inc., a company focused on cardiac care, ran into a dilemma. Its Impella 2.5 device was approved for use in the European Union, but CEO Michael Minogue had seemingly bet the company's future on the ability... View Details
Keywords: Mergers and Acquisitions; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Business and Government Relations; Medical Devices and Supplies Industry; European Union; United States
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Tadikonda, Satish, Faith Robertson, and William Marks. "Abiomed: A Change of Heart." Harvard Business School Case 825-011, February 2025.
  • January 2014 (Revised December 2014)
  • Case

GenapSys: Business Models for the Genome

By: Richard G. Hamermesh, Joseph B. Fuller and Matthew Preble

GenapSys, a California-based startup, was soon to release a new DNA sequencer that the company's founder, Hesaam Esfandyarpour, believed was truly revolutionary. The sequencer would be substantially less expensive—potentially costing just a few thousand dollars—and... View Details

Keywords: DNA Sequencing; Life Sciences; Business Model; Innovation & Entrepreneurship; Health Care and Treatment; Genetics; Business Strategy; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; United States
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Hamermesh, Richard G., Joseph B. Fuller, and Matthew Preble. "GenapSys: Business Models for the Genome." Harvard Business School Case 814-050, January 2014. (Revised December 2014.)
  • October 2015
  • Article

Exposed: Venture Capital, Competitor Ties, and Entrepreneurial Innovation

By: Emily Cox Pahnke, Rory McDonald, Dan Wang and Benjamin Hallen
This paper investigates the impact of early relationships on innovation at entrepreneurial firms. Prior research has largely focused on the benefits of network ties, documenting the many advantages that accrue to firms embedded in a rich network of inter-organizational... View Details
Keywords: Competition; Intellectual Property; Entrepreneurship; Innovation and Invention; Medical Devices and Supplies Industry
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Pahnke, Emily Cox, Rory McDonald, Dan Wang, and Benjamin Hallen. "Exposed: Venture Capital, Competitor Ties, and Entrepreneurial Innovation." Academy of Management Journal 58, no. 5 (October 2015): 1334–1360.
  • Research Summary

Overview

Navid has worked with different organizations across various industries, from the Federal Reserve to medical device manufacturers, heavy construction equipment sellers, and B2B software providers, to assemble proprietary datasets in studying organizational buying.... View Details

  • July–August 2024
  • Article

The Middle Path to Innovation

By: Regina E. Herzlinger, Duke Rohlen, Ben Creo and Will Kynes
Too many companies are failing to innovate. One reason, say the authors, is the polarized approach companies take to innovation. At one end of the spectrum, corporate R&D efforts tend to focus on product refreshes and incremental line upgrades that generate modest... View Details
Keywords: Innovation Strategy; Medical Devices and Supplies Industry
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Herzlinger, Regina E., Duke Rohlen, Ben Creo, and Will Kynes. "The Middle Path to Innovation." Harvard Business Review 102, no. 4 (July–August 2024): 134–145.
  • November 2022
  • Teaching Note

Proximie: Using XR Technology to Create Borderless Operating Rooms

By: Ariel D. Stern, Alpana Thapar and Menna Hassan
Founded by Nadine Hachach-Haram in 2016, Proximie was a digital medicine platform that used mixed reality and a host of digital audio and visual tools to enable clinicians, proctors, and medical device company personnel to be virtually present in operating rooms (ORs),... View Details
Keywords: Technological Innovation; Business Growth and Maturation; Growth and Development Strategy; Corporate Social Responsibility and Impact; Decision Making; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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Stern, Ariel D., Alpana Thapar, and Menna Hassan. "Proximie: Using XR Technology to Create Borderless Operating Rooms." Harvard Business School Teaching Note 623-034, November 2022.
  • August 2009 (Revised June 2015)
  • Case

MINTing Innovation at NewYork-Presbyterian (A)

By: Richard G. Hamermesh and David Kiron
Several top surgeons at NewYork-Presbyterian Hospital (NYP) are receiving financial and administrative support to advance their surgical device inventions through the earliest stages of commercialization. View Details
Keywords: Health Care; Innovation & Entrepreneurship; Hospital; Entrepreneurship; Financing and Loans; Investment; Health Care and Treatment; Innovation and Invention; Intellectual Property; Commercialization; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; New York (state, US)
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Hamermesh, Richard G., and David Kiron. "MINTing Innovation at NewYork-Presbyterian (A)." Harvard Business School Case 810-004, August 2009. (Revised June 2015.)
  • 2008
  • Article

Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States

By: Michel Anteby and Mikell Hyman

Human cadavers are crucial to medical science. While the debate on how to secure sufficient cadavers has focused primarily on donors' behaviors, procuring organizations' roles in increasing donations remain less explored. The United States offers a unique setting in... View Details

Keywords: Entrepreneurship; Behavior; Programs; Nonprofit Organizations; Business Ventures; Health Testing and Trials; Demand and Consumers; Supply Chain; For-Profit Firms; Organizations; Training; United States
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Anteby, Michel, and Mikell Hyman. "Entrepreneurial Ventures and Whole-body Donations: A Regional Perspective from the United States." Social Science & Medicine 66, no. 4 (2008): 963–969.
  • October 2009
  • Case

Medisys Corp.: The IntensCare Product Development Team

By: Anne Donnellon and Joshua D. Margolis
Key topics include designing teams, managing teams, managing conflict, group dynamics, project management, product development, interdepartmental relations, and organizational change. MediSys, a U.S.-based medical equipment maker, has been developing IntensCare, a new... View Details
Keywords: Project Management; Interdepartmental Relations; Organizational Change; Leadership; Conflict Management; Interpersonal Communication; Groups and Teams; Product Design; Product Development; Organizational Change and Adaptation; Health Care and Treatment; Power and Influence; Medical Devices and Supplies Industry; United States
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Donnellon, Anne, and Joshua D. Margolis. "Medisys Corp.: The IntensCare Product Development Team." Harvard Business School Brief Case 094-059, October 2009.
  • June 2012
  • Case

Innovating at AT&T: Partnering to Lead the Broadband Revolution

By: Lynda M. Applegate, Phillip Andrews and Kerry Herman
In 2010, the U.S. retail market value for next-generation non-handset wirelessly-enabled devices was just over $1 billion. By 2011 it had grown 1,141% to $13.2 billion and was forecast to reach $24.7 billion in 2015. At the same time, user demand for data was surging... View Details
Keywords: Innovation & Entrepreneurship; Team Leadership; Emerging Technologies; Business Models; Business To Business; Corporate Vision; Growth Strategy; Corporate Culture; Innovation and Invention; Corporate Entrepreneurship; Partners and Partnerships; Leadership; Mobile and Wireless Technology; Growth and Development Strategy; Globalized Firms and Management; Business Model; Technology Industry; United States
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Applegate, Lynda M., Phillip Andrews, and Kerry Herman. "Innovating at AT&T: Partnering to Lead the Broadband Revolution." Harvard Business School Case 812-124, June 2012.
  • 2020
  • Working Paper

Pioneer (Dis-)advantages in Markets for Technology

By: Moritz Fischer, Joachim Henkel and Ariel Dora Stern
This study sheds new light on first- and early-mover advantages in the context of product innovation. Research on this classic topic often assumes that each firm participates in the entirety of the innovation and commercialization process. However, a division of labor... View Details
Keywords: First-mover Advantage; Product; Innovation Strategy; Market Entry and Exit; Acquisition; Technology
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Fischer, Moritz, Joachim Henkel, and Ariel Dora Stern. "Pioneer (Dis-)advantages in Markets for Technology." Harvard Business School Working Paper, No. 19-043, October 2018. (Revised March 2020.)
  • February 2019 (Revised September 2019)
  • Case

Theranos: The Unicorn That Wasn't

By: Joseph B. Fuller and John Masko
In 2003, 19-year-old Elizabeth Holmes founded a startup dedicated to making blood testing easier and more affordable. By 2015, her company, Theranos, was worth $9 billion. It boasted a star-studded board and contracts with national pharmacy and supermarket chains... View Details
Keywords: Theranos; Blood; Lab Testing; Fraud; Holmes; Balwani; Shultz; Carreyrou; Securities And Exchange Commission; Food And Drug Administration; FDA; SEC; Health Testing and Trials; Corporate Accountability; Organizational Culture; Misleading and Fraudulent Advertising; Crime and Corruption; Entrepreneurship; Medical Devices and Supplies Industry
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Fuller, Joseph B., and John Masko. "Theranos: The Unicorn That Wasn't." Harvard Business School Case 319-068, February 2019. (Revised September 2019.)
  • November 2020 (Revised March 2023)
  • Case

Zipline: The World's Largest Drone Delivery Network

By: Tarun Khanna and George Gonzalez
Zipline established the world's largest logistics network in Rwanda and Ghana by delivering medical supplies to hospitals via automated drones. The company is now looking to expand in the U.S. and partnered with Walmart to expand into home delivery. Zipline must... View Details
Keywords: Drones; Business Startups; Expansion; Growth and Development Strategy; Governing Rules, Regulations, and Reforms; Medical Devices and Supplies Industry; United States; Africa
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Khanna, Tarun, and George Gonzalez. "Zipline: The World's Largest Drone Delivery Network." Harvard Business School Case 721-366, November 2020. (Revised March 2023.)
  • March 2022 (Revised August 2022)
  • Case

Proximie: Using XR Technology to Create Borderless Operating Rooms

By: Ariel D. Stern and Alpana Thapar
In mid-January 2022, Nadine Hachach-Haram, founder and CEO of Proximie, was thinking about the company’s growth plans. Launched in 2016, Proximie was a platform that enabled clinicians, proctors, and medical device company personnel to be virtually present in operating... View Details
Keywords: Growth and Development Strategy; Technological Innovation; Partners and Partnerships; Strategic Planning; Health Care and Treatment; Analytics and Data Science; Digital Platforms; Health Industry; Lebanon; United Kingdom; United States
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Stern, Ariel D., and Alpana Thapar. "Proximie: Using XR Technology to Create Borderless Operating Rooms." Harvard Business School Case 622-082, March 2022. (Revised August 2022.)
  • September 1986
  • Case

BOC Group: Ohmeda (A)

The president of Ohmeda, a wholly owned company of the BOC Group, plans to grow the company's medical equipment sales from $95 million in 1985 to $158 million in five years by focusing on the sale of "high-tech" equipment. At the same time, the president expects to... View Details
Keywords: Marketing Communications; Salesforce Management; Marketing Channels; Medical Devices and Supplies Industry
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Moriarty, Rowland T., Jr. "BOC Group: Ohmeda (A)." Harvard Business School Case 587-080, September 1986.
  • November 2006
  • Case

Brontes Technologies -- 2005

By: William A. Sahlman and Caroline Perkins
Describes a set of decisions confronting the founders of a company developing a new device for taking three-dimensional pictures of teeth in order to improve dental outcomes. The company needs more money and must choose between raising new equity capital from a venture... View Details
Keywords: Borrowing and Debt; Business Startups; Medical Devices and Supplies Industry
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Sahlman, William A., and Caroline Perkins. "Brontes Technologies -- 2005." Harvard Business School Case 807-101, November 2006.
  • July–August 2021
  • Article

Lowering the Bar? External Conditions, Opportunity Costs, and High-Tech Startup Outcomes

By: Annamaria Conti and Maria P. Roche
We assess the heterogeneous impact of economic downturns on individuals’ decisions to bring high-technology ideas to the market in the form of new ventures. We thereby examine how worsening labor market conditions influence individuals’ opportunity costs of starting... View Details
Keywords: Necessity Entrepreneurship; Economic Conditions; Recessions; High-tech Startups; Opportunity Costs; Entrepreneurship; Economic Slowdown and Stagnation; Business Startups; Information Technology; Performance; Labor
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Conti, Annamaria, and Maria P. Roche. "Lowering the Bar? External Conditions, Opportunity Costs, and High-Tech Startup Outcomes." Organization Science 32, no. 4 (July–August 2021): 965–986.
  • November–December 2015
  • Article

Active Postmarketing Drug Surveillance for Multiple Adverse Events

By: Joel Goh, Margrét V. Bjarnadóttir, Mohsen Bayati and Stefanos A. Zenios
Postmarketing drug surveillance is the process of monitoring the adverse events of pharmaceutical or medical devices after they are approved by the appropriate regulatory authorities. Historically, such surveillance was based on voluntary reports by medical... View Details
Keywords: Drug Surveillance; Health Care; Stochastic Models; Queueing; Diffusion Approximation; Brownian Motion; Health Care and Treatment; Analytics and Data Science; Analysis
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Goh, Joel, Margrét V. Bjarnadóttir, Mohsen Bayati, and Stefanos A. Zenios. "Active Postmarketing Drug Surveillance for Multiple Adverse Events." Operations Research 63, no. 6 (November–December 2015): 1528–1546. (Finalist, 2012 INFORMS Health Applications Society Pierskalla Award.)
  • 20 Dec 2016
  • First Look

December 20, 2016

to creating your own model. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=52002 January 2017 Journal of Public Economics Innovation Under Regulatory Uncertainty: Evidence from Medical Technology By: Stern, Ariel Dora... View Details
Keywords: Carmen Nobel
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