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- January 2024
- Case
Vibrant Health
By: Henry McGee and Sarah Mehta
This case is about nutritional supplements company Vibrant Health, among the 100 largest Black-owned businesses in the U.S. After acquiring the company from its white founder in 2007, co-owners Ted and Paige Parker significantly grew its sales. Set in September 2023,... View Details
- January 2024
- Technical Note
The ICARUS Principles: What It Takes to Tackle the World
By: Debora L. Spar and Julia M. Comeau
Over the course of the 20th century, most of the world’s major multinational corporations framed their mission around Milton Friedman’s famous mantra: that the sole purpose of the firm is to maximize its shareholders’ profits. Recently, however, growing numbers of... View Details
- January 2024
- Article
A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder
By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan
The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details
- January 2024
- Article
Cost of Exempting Sole Orphan Drugs from Medicare Negotiation
By: Matthew Vogel, Olivia Zhao, William B. Feldman, Amitabh Chandra, Aaron S. Kesselheim and Benjamin N. Rome
Importance: The Inflation Reduction Act (IRA) requires Medicare to negotiate prices for some high-spending drugs but exempts drugs approved solely for the treatment of a single rare disease.
Objective: To estimate Medicare spending and global... View Details
Objective: To estimate Medicare spending and global... View Details
- January–February 2024
- Article
Shared Service Delivery Can Increase Client Engagement: A Study of Shared Medical Appointments
By: Ryan W. Buell, Kamalini Ramdas, Nazlı Sönmez, Kavitha Srinivasan and Rengaraj Venkatesh
Problem Definition: Clients and service providers alike often consider one-on-one service delivery to be ideal, assuming – perhaps unquestioningly – that devoting individualized attention best improves client outcomes. In contrast, in shared service delivery, clients... View Details
- January 2024
- Article
Subset Scanning for Multi-Trait Analysis Using GWAS Summary Statistics
By: Rui Cao, Evan Olawsky, Edward McFowland III, Erin Marcotte, Logan Spector and Tianzhong Yang
Multi-trait analysis has been shown to have greater statistical power than single-trait analysis. Most of the existing multi-trait analysis methods only work with a limited number of traits and usually prioritize high statistical power over identifying relevant traits,... View Details
- December 2023 (Revised March 2024)
- Case
Manufacturing Moderna's Future
By: Satish Tadikonda and William Marks
In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details
- December 2023 (Revised February 2024)
- Case
Transforming Healthcare Delivery at Karolinska University Hospital
By: Susanna Gallani, Mary Witkowski, Elena Corsi and Nikolina Jonsson
The case study examines the journey toward value-based healthcare at Karolinska University Hospital. The hospital's ambitious shift to a patient-centered care delivery model, accompanied by the construction of a new facility, encountered challenges such as high costs,... View Details
- December 2023
- Teaching Note
Buurtzorg
By: Ethan Bernstein and Tatiana Sandino
Teaching Note for HBS Case No. 122-101. As co-founders of home nursing company Buurtzorg, Jos de Blok and Gonnie Kronenberg prized both self-management and organizational learning. Buurtzorg’s 10,000 nurses across 950 neighborhood nursing teams in the Netherlands were... View Details
- December 12, 2023
- Article
Prices for Common Services at Quaternary vs Nonquaternary Hospitals
By: Brandon W. Yan, Maximilian J. Pany and Leemore S. Dafny
Using commercial health insurance claims data from 2017-2019, we assessed whether quaternary hospitals charged higher prices for common, unspecialized services also offered by nonquaternary hospitals. We found quaternary-hospital price premiums of 8.2 percent, on... View Details
- December 4, 2023
- Comment
The Great Resignation, Employment, and Wages in Health Care
By: Amitabh Chandra and Louis-Jonas Heizlsperger
Notwithstanding concerns about staffing levels and burnout in health care, federal wage and employment data does not support the suggestion that a COVID-19 pandemic-related spike in quitting has had an enduring impact for hospitals or physician offices. Employment in... View Details
- December 2023
- Article
Association of Hospital System Affiliation with COVID-19 Capacity Burden
By: Zachary Levin, Pinar Karaca-Mandic, Richard J. Boxer and Regina E. Herzlinger
What is the message? The COVID-19 pandemic exposed the highly variable and uncoordinated responses by hospitals. The authors found that while the non-top ten system affiliated hospitals had a larger COVID-19 share index relative to independent hospitals, top-ten system... View Details
- 2023
- Article
Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset
By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details
- December 2023
- Case
Gabriela Santana Goldstein
By: Leslie Perlow and Hannah Weisman
Gabriela Santana Goldstein was pursuing her passion, working as the Head of Business for a telehealth startup, when her father went into sudden cardiac arrest and family duty called. The case discusses Goldstein’s difficult decision to leave her dream job, and her path... View Details
- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
- November 20, 2023
- Article
How Ben Minicucci Piloted Alaska Airlines Through the Pandemic
By: Ranjay Gulati
- November 2023
- Case
Swanson Health: Becoming a Super Seller
By: William R. Kerr, Daniel O'Connor and Paige Boehmcke
Founded in 1969, Swanson Health sold vitamins, supplements, natural health products, and organic foods. Over the years, the company had successfully navigated multiple industry transitions as it expanded from a print catalog to sell products on its own... View Details
- November 2023
- Case
Nourishing Communities: Brighter Bites Approach to Childhood Nutrition
By: David E. Bell, Forest Reinhardt and Ai-Ling Jamila Malone
In September 2023, Brighter Bites, a Houston-based non-profit that distributed fresh produce and nutrition education in underserved communities across 11 cities and 5 states, grappled with identifying the best path forward for continued growth. Brighter Bites proved... View Details
- 2023
- Working Paper
Healthcare Provider Bankruptcies
By: Samuel Antill, Jessica Bai, Ashvin Gandhi and Adrienne Sabety
Healthcare firms are increasingly filing for Chapter 11 bankruptcy. Using two strategies, we show causal evidence that bankruptcies harm patients through increased worker turnover. First, in an online experiment, experienced nurses assess hypothetical employers and... View Details
- October 2023
- Supplement
Hey Jane: Background on Abortion in the U.S.
By: Rembrand Koning, Geraldine Pena-Galea and Sarah Mehta