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  • All HBS Web  (9,193)
    • People  (29)
    • News  (1,599)
    • Research  (6,099)
    • Events  (32)
    • Multimedia  (20)
  • Faculty Publications  (4,572)
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  • February 2024
  • Article

Representation and Extrapolation: Evidence from Clinical Trials

By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it... View Details
Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
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Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
  • January 2018
  • Article

The Central and Unacknowledged Role of the U.S. Food and Drug Administration in the Design and Execution of Medical Device Pivotal Trials

By: Aaron V. Kaplan and Ariel D. Stern
The introduction of new medical devices has transformed cardiovascular care in recent decades. Devices, such as heart valves, pacemakers, stents, ventricular assist devices, and implantable defibrillators, have prolonged and improved the quality of life for millions of... View Details
Keywords: Health Testing and Trials; Business and Government Relations; Governing Rules, Regulations, and Reforms; Information Publishing; Medical Devices and Supplies Industry; United States
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Kaplan, Aaron V., and Ariel D. Stern. "The Central and Unacknowledged Role of the U.S. Food and Drug Administration in the Design and Execution of Medical Device Pivotal Trials." JAMA Cardiology 3, no. 1 (January 2018): 5–6.
  • 11 Aug 2003
  • Research & Ideas

Cheap, Fast, and In Control: How Tech Aids Innovation

modifications to major new innovations. The user-friendly tools, often integrated into a "toolkit" package, deploy new technologies (e.g., computer simulation and... View Details
Keywords: by Wendy Guild

    Balancing Risk and Reward: An Automated Phased Release Strategy

    Phased releases are a common strategy in the technology industry for gradually releasing new products or updates through a sequence of A/B tests in which the number of treated units gradually grows until full deployment or deprecation. Performing phased releases... View Details
    • September 2016 (Revised September 2016)
    • Case

    The Tavistock Group and the Australian Agricultural Company

    By: Dante Roscini and Matthew Preble
    In late 2015, Dr. Shehan Dissanayake, a managing director and board member of Bahamian investment firm The Tavistock Group (Tavistock), the largest shareholder in the Australian Agricultural Company (AACo), one of the country's largest agribusinesses, faces a... View Details
    Keywords: Agribusiness; Foreign Direct Investment; Cross-Cultural and Cross-Border Issues; Business and Government Relations; Agriculture and Agribusiness Industry; Australia; Bahamas
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    Roscini, Dante, and Matthew Preble. "The Tavistock Group and the Australian Agricultural Company." Harvard Business School Case 717-009, September 2016. (Revised September 2016.)
    • January 1996 (Revised March 1998)
    • Case

    Linking Strategy and Innovation: Materials Technology Corporation

    By: Clayton M. Christensen
    Materials Technology Corp. (MTC), a high-tech materials company, is struggling in its development portfolio and to achieve a better record of delivering new products on time. View Details
    Keywords: Technology; Innovation and Invention; Business Strategy; Time Management; Product; Production; Manufacturing Industry; Manufacturing Industry; Manufacturing Industry; United States
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    Christensen, Clayton M. "Linking Strategy and Innovation: Materials Technology Corporation." Harvard Business School Case 696-082, January 1996. (Revised March 1998.)
    • 05 Jan 2009
    • Research & Ideas

    Most Popular Articles and Working Papers 2008

    shape strategy. We excerpt a portion on advice for new CEOs, written with HBS faculty Jay W. Lorsch and Nitin Nohria. 3. Why Don't Managers Think Deeply? Professor Jim Heskett poses this provacative question... View Details
    Keywords: by Staff
    • May 1994 (Revised January 1995)
    • Case

    Warner Cable (A) and (B) (Condensed)

    The new general manager of Warner Cable's Medford, Massachusetts complex faces a number of turnaround challenges in 1985, including service deficiencies, customer complaints, high turnover, and low employee morale. By 1988 he has turned the situation around, but some... View Details
    Keywords: Organizational Change and Adaptation; Management Style; Change Management; Performance Improvement; Telecommunications Industry; Massachusetts
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    Sonnenfeld, Jeffrey A. "Warner Cable (A) and (B) (Condensed)." Harvard Business School Case 394-198, May 1994. (Revised January 1995.)
    • 2007
    • Working Paper

    Irving Fisher, Economic Forecasting, and the Myth of the Business Cycle

    By: Walter A. Friedman
    A premier economist of the twentieth century and a founder of neoclassical thought, Irving Fisher was also an active participant in the field of economic forecasting. Fisher made theoretical contributions to the understanding of economic fluctuations, popularized the... View Details
    Keywords: Forecasting and Prediction; Economics; Business Cycles; Business History; Newspapers; Personal Development and Career
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    Friedman, Walter A. "Irving Fisher, Economic Forecasting, and the Myth of the Business Cycle." Harvard Business School Working Paper, No. 08-037, November 2007.
    • Article

    Designing Social Networks: Joint Tasks and the Formation and Endurance of Network Ties

    By: Sharique Hasan and Rembrand Koning
    Can managers influence the formation of organizational networks? In this article, we evaluate the effect of joint tasks on the creation of network ties with data from a novel field experiment with 112 aspiring entrepreneurs. During the study, we randomized individuals... View Details
    Keywords: Accelerators; Entrepreneur; Social Networks; Field Experiment; Entrepreneurship; Organizational Design; Networks; Social and Collaborative Networks; Social Media; Information Technology Industry; India
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    Hasan, Sharique, and Rembrand Koning. "Designing Social Networks: Joint Tasks and the Formation and Endurance of Network Ties." Art. 4. Journal of Organization Design 9 (2020).
    • April 2008
    • Teaching Note

    Richard Grasso and the NYSE, Inc. (TN) (A) and (B)

    By: William W. George
    Teaching Note for [405051] and [405068]. View Details
    Keywords: Financial Services Industry; New York (state, US)
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    George, William W. "Richard Grasso and the NYSE, Inc. (TN) (A) and (B)." Harvard Business School Teaching Note 408-119, April 2008.
    • Web

    Publications - Institute For Strategy And Competitiveness

    Medicare payments, primarily from decreased hospital LOS and post-acute care utilization. October 2019 New England Journal of Medicine Catalyst Achieving Value in Highly... View Details
    • September 2011 (Revised February 2014)
    • Case

    Duke Energy and the Nuclear Renaissance

    By: Richard H.K. Vietor and Forest L. Reinhardt
    Duke Energy, an American investor-owned electric utility, confronts multibillion dollar decisions about its future fuel mix. In particular, its leaders are considering building new nuclear capacity. Whether this is sensible depends, among other things, on demand... View Details
    Keywords: Cost vs Benefits; Expansion; Policy; Business Strategy; Energy Sources; Utilities Industry; Energy Industry; United States
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    Vietor, Richard H.K., and Forest L. Reinhardt. "Duke Energy and the Nuclear Renaissance." Harvard Business School Case 712-002, September 2011. (Revised February 2014.)
    • Web

    UrSure, Inc. wins 2016 New Venture Competition Social Enterprise Track | Social Enterprise | Harvard Business School

    UrSure, Inc. wins 2016 New Venture Competition Social Enterprise Track More Impact Stories A Pathway to Pursue Aspirations Mizuho Kanai 2018 While Mizuho Kanai (MBA 2018) was fulfilling her summer internship at NPR, her manager... View Details
    • March 2020
    • Case

    A Tower for the People: 425 Park Avenue

    By: John Macomber, Joseph G. Allen and Emily Jones
    Healthy buildings and superior air quality are increasingly important since people now spend so much time indoors. Indoor spaces drive performance and productivity. Commercial real estate landlords and investors are responding to the demands of sophisticated tenants... View Details
    Keywords: Health And Wellness; Real Estate; Sustainability; Health; Pollution; Buildings and Facilities; Performance Productivity; Finance; Real Estate Industry; New York (city, NY)
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    Macomber, John, Joseph G. Allen, and Emily Jones. "A Tower for the People: 425 Park Avenue." Harvard Business School Case 220-065, March 2020.
    • Web

    Financing New Ideas - Georges F. Doriot : Educating Leaders, Building Companies, Baker Library, Harvard Business School

    inspired New England's high-tech boom and the spread of companies that began to populate Route 128 surrounding Boston and Cambridge. A number of ARD employees also went on to... View Details
    • October 2012 (Revised March 2022)
    • Case

    Kleiner-Perkins and Genentech: When Venture Capital Met Science

    By: Felda Hardymon and Tom Nicholas
    Genentech is a rare success story in the biotechnology industry. Hundreds of billions of dollars of venture capital have been invested without the expected transformational effects. Established in 1976, Genentech was to develop the new science of recombinant DNA into... View Details
    Keywords: Innovation & Entrepreneurship; Venture Capital; Innovation and Invention; Entrepreneurship; Information Technology; Science; Biotechnology Industry; United States
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    Hardymon, Felda, and Tom Nicholas. "Kleiner-Perkins and Genentech: When Venture Capital Met Science." Harvard Business School Case 813-102, October 2012. (Revised March 2022.)
    • April 1992 (Revised March 1993)
    • Case

    Brigham and Women's Hospital in 1992, The

    Brigham and Women's Hospital is a highly successful teaching hospital in 1992. However, the hospital sector is undergoing a major transition and the hospital faces uncertainty about changing demographic trends, new types of competitors, and technological and scientific... View Details
    Keywords: Risk and Uncertainty; Change Management; Social Entrepreneurship; Decision Making; Health Care and Treatment; Business Strategy; Education Industry; Education Industry; Massachusetts
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    Teisberg, Elizabeth O. "Brigham and Women's Hospital in 1992, The ." Harvard Business School Case 792-095, April 1992. (Revised March 1993.)
    • Web

    Clusters - Institute For Strategy And Competitiveness

    01 June 2006 HBS Case Collection MassMEDIC: The Massachusetts Medical Device Industry Council by Willis M. Emmons III, Michael E. Porter and Spencer Wallace 04 May 2012 HBS student project Tennessee Music... View Details
    • November 2000 (Revised March 2001)
    • Case

    Alaska Airlines and Flight 261 (A)

    Weeks after the crash of Alaska Airlines Flight 261, 64 mechanics claim that they have been "pressured, threatened, and intimidated" into taking shortcuts. After briefly describing Alaska Airlines' history and CEO John Kelly, the case details how the airline responded... View Details
    Keywords: Safety; Air Transportation; Crisis Management; Labor and Management Relations; Air Transportation Industry; Alaska
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    Watkins, Michael D., and Kim Slack. "Alaska Airlines and Flight 261 (A)." Harvard Business School Case 801-113, November 2000. (Revised March 2001.)
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