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  • All HBS Web  (2,820)
    • People  (8)
    • News  (334)
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General Merchants to Commodities Brokers | Baker Library | Bloomberg Center | Harvard Business School

Introduction 1840s – 1880s General Merchants to Commodities Brokers 1880s – 1920s Investment Banking & Securities Underwriting 1920s – 1960s Investing in Emerging Industries 1850–1968 Lehman Brothers Family Partners 1960s – 2000s... View Details
  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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Bagley, Nicholas, Benjamin Berger, Amitabh Chandra, Craig Garthwaite, and Ariel Dora Stern. "The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century." Chap. 4 in Innovation Policy and the Economy, Volume 19, edited by Josh Lerner and Scott Stern, 97–137. University of Chicago Press, 2018.
  • November–December 2024
  • Article

Scaling Up Transformational Innovations

By: Peter Koen, Ananya Sheth, Mike DiPaola and Linda A. Hill
For large companies operating in mature sectors—such as Procter & Gamble in consumer goods, Apple in consumer electronics, and Adobe in cloud software—driving growth is a perennial challenge. Growth through acquisition is always an option, but companies often quickly... View Details
Keywords: Growth and Development Strategy; Leadership; Innovation Strategy; Consumer Products Industry
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Koen, Peter, Ananya Sheth, Mike DiPaola, and Linda A. Hill. "Scaling Up Transformational Innovations." Harvard Business Review 102, no. 6 (November–December 2024): 78–85.
  • April 2003 (Revised December 2006)
  • Case

ZARA: Fast Fashion

By: Pankaj Ghemawat and Jose Luis Nueno
Focuses on Inditex, an apparel retailer from Spain, which has set up an extremely quick response system for its ZARA chain. Instead of predicting months before a season starts what women will want to wear, ZARA observes what's selling and what's not and continuously... View Details
Keywords: Organizational Change and Adaptation; Multinational Firms and Management; Competitive Advantage; Manufacturing Industry; Manufacturing Industry; Manufacturing Industry; Spain
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Ghemawat, Pankaj, and Jose Luis Nueno. "ZARA: Fast Fashion." Harvard Business School Case 703-497, April 2003. (Revised December 2006.)
  • 16 Jan 2013
  • Research & Ideas

The Messy Link Between Slave Owners and Modern Management

Caitlin C. Rosenthal didn't intend to write a book about slavery. She set out to tackle something much more mundane: the history of business practices. But when she started researching account books from the mid-1800s, a period of major economic development during the... View Details
Keywords: by Katie Johnston
  • 26 Sep 2006
  • First Look

First Look: September 26, 2006

  Working PapersScale Without Mass: Business Process Replication and Industry Dynamics Authors:Erik Brynjolfsson, Andrew McAfee, Michael Sorell, and Feng Zhu Abstract Since the mid-1990s, productivity growth has accelerated in the U.S.... View Details
Keywords: Sean Silverthorne
  • June 2012
  • Teaching Note

Harvest: Organic Waste Recycling with Energy Recovery (TN) (A) and (B)

By: Deishin Lee
This case describes the waste management industry and a clean technology solution for landfill diversion and renewable energy production. The (A) case focuses on the operational characteristics of organic waste recycling with energy recovery, and the characteristics of... View Details
Keywords: Sustainability; Waste Management; Sourcing; Operations Management; Environment; Wastes and Waste Processing; Renewable Energy; Operations; Supply Chain Management; Utilities Industry; Utilities Industry
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Lee, Deishin. "Harvest: Organic Waste Recycling with Energy Recovery (TN) (A) and (B)." Harvard Business School Teaching Note 612-107, June 2012.
  • 07 Dec 2010
  • First Look

First Look: Dec. 7

copyrighted content over peer-to-peer (p2p) file sharing networks and its impact on the music industry and to assess the viable business models for the industry in the future. Competitiveness: Business Model... View Details
Keywords: Sean Silverthorne
  • Article

Management Practices, Relational Contracts and the Decline of General Motors

By: Susan Helper and Rebecca Henderson
General Motors was once regarded as one of the best managed and most successful firms in the world, but between 1980 and 2009 its share of the U.S. market fell from 62.6% to 19.8%, and in 2009 the firm went bankrupt. In this paper we argue that the conventional... View Details
Keywords: Organizational Design; Management Practices and Processes; Insolvency and Bankruptcy; Manufacturing Industry; Manufacturing Industry; United States
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Helper, Susan, and Rebecca Henderson. "Management Practices, Relational Contracts and the Decline of General Motors." Journal of Economic Perspectives 28, no. 1 (Winter 2014): 49–72.
  • 05 Jul 2022
  • What Do You Think?

Have We Seen the Peak of Just-in-Time Inventory Management?

distribution channel. Fluctuating demand at the retail level would generate exaggerated fluctuations—a “whipsaw” effect—in expected demand and inventory planning at the back end, or manufacturing level, in an effort to meet possible... View Details
Keywords: by James Heskett; Manufacturing; Manufacturing; Manufacturing

    Stefan H. Thomke

    Stefan Thomke (sthomke@hbs.edu), an authority on the management of innovation, is the William Barclay Harding Professor of Business Administration at Harvard Business School. He has worked with firms on product, process, and... View Details

    Keywords: information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry; information technology industry

      William A. Sahlman

      William Sahlman is a Baker Foundation Professor of Business Administration at Harvard Business School.

      Mr. Sahlman received an A.B. degree in Economics from Princeton University (1972), an M.B.A. from Harvard University (1975), and a Ph.D. in Business... View Details

      Keywords: e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry; e-commerce industry
      • September 2023 (Revised May 2025)
      • Teaching Note

      On

      By: Ramon Casadesus-Masanell, Karolin Frankenberger, Sascha Mader, Jordan Mitchell and Karen Elterman
      Teaching Note for "On," HBS Case No. 723-430. On is a premium performance running shoe company founded in Switzerland in 2010. The company rapidly gained traction through its unique CloudTec cushioning technology, its innovative midsole plate called the Speedboard, and... View Details
      Keywords: Brands and Branding; Business Growth and Maturation; Business Model; Business Startups; Business Strategy; Competitive Advantage; Competitive Strategy; Corporate Strategy; Customer Focus and Relationships; Customer Satisfaction; Digital Marketing; Disruptive Innovation; Distribution Channels; Entrepreneurship; Environmental Sustainability; Global Strategy; Initial Public Offering; Innovation and Invention; Innovation Strategy; Market Entry and Exit; Marketing Strategy; Product Design; Product Development; Product Marketing; Social Media; Strategy; Supply Chain Management; Technological Innovation; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Apparel and Accessories Industry; Europe; Germany; Switzerland; United States
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      Casadesus-Masanell, Ramon, Karolin Frankenberger, Sascha Mader, Jordan Mitchell, and Karen Elterman. "On (A) and (B)." Harvard Business School Teaching Note 724-375, September 2023. (Revised May 2025.)
      • 10 Dec 2007
      • HBS Case

      One Laptop per Child

      agreed to manufacture the laptop. On the technological front, OLPC tackled puzzles such as creating a product both useful and fun for children of primary school age. (See CloseUp below). But despite its visionary goals and widespread... View Details
      Keywords: by Martha Lagace; Computer
      • 03 Oct 2005
      • Research & Ideas

      The Truck Driver Who Reinvented Shipping

      Malcolm P. McLean, a truck driver, fundamentally transformed the centuries-old shipping industry, an industry that had long decided that it had no incentive to change. By developing the first safe, reliable, and cost effective approach to... View Details
      Keywords: by Anthony J. Mayo & Nitin Nohria; Manufacturing; Manufacturing; Manufacturing
      • February 2022 (Revised February 2024)
      • Case

      Sekisui House and the In-Home Early Detection Platform

      By: John D. Macomber and Akiko Kanno
      To address an aging population and sales declines, a major Japanese homebuilder considers pivoting to provide and support an in-home health detection platform, in competition with tech companies. This case considers the point of view of major builders regarding how... View Details
      Keywords: Voice Assistants; Architecture; Smart Home; Aging Society; Digitalization; Real Estate; Home Automation; Sensors; Strategy; Digital Platforms; Health Care and Treatment; Housing; Age; Real Estate Industry; Real Estate Industry; Real Estate Industry; Japan
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      Macomber, John D., and Akiko Kanno. "Sekisui House and the In-Home Early Detection Platform." Harvard Business School Case 222-070, February 2022. (Revised February 2024.)
      • 19 Apr 2010
      • Research & Ideas

      The History of Beauty

      necessary finance, there are contract manufacturers and perfumers that will provide a product for you. This is also an industry subject to sudden shifts in fashion and fads, which disrupt incumbent positions... View Details
      Keywords: by Sean Silverthorne; Beauty & Cosmetics
      • February 1992 (Revised March 1993)
      • Case

      Intel Corp.--1992

      By: Kenneth A. Froot
      Intel Corp., the world's dominant designer and manufacturer of microprocessors (the "brains" of the personal computer), has accumulated a large amount of cash (net of debt). Furthermore, it expects to continue to accumulate cash at an unprecedented rate. Has the... View Details
      Keywords: Dividends; Financial Management; Competition; Multinational Firms and Management; Cash; Technological Innovation; Capital Structure; Investment Return; Equity; Financial Strategy; Corporate Finance; Semiconductor Industry; United States
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      Froot, Kenneth A. "Intel Corp.--1992." Harvard Business School Case 292-106, February 1992. (Revised March 1993.)
      • September 2019 (Revised August 2020)
      • Case

      Engineering an Inclusive Bioeconomy

      By: Tarun Khanna, Raffaella Sadun and Susie L. Ma
      In 2019, entrepreneur Juan Carlos Castilla-Rubio was developing a project he hoped could generate and share wealth from the natural resources of the Amazon without destroying those resources. His idea, called Earth Bank of Codes (EBC), would create a library of the... View Details
      Keywords: Decision Making; Development Economics; Entrepreneurship; Innovation and Invention; Intellectual Property; Emerging Markets; Market Design; Marketplace Matching; Science; Genetics; Natural Environment; Environmental Sustainability; Climate Change; Social Enterprise; Strategy; Strategic Planning; Information Technology; Ownership; Social Psychology; Trust; Society; Biotechnology Industry; South America; Amazon Basin
      Citation
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      Khanna, Tarun, Raffaella Sadun, and Susie L. Ma. "Engineering an Inclusive Bioeconomy." Harvard Business School Case 720-356, September 2019. (Revised August 2020.)
      • 03 Nov 2009
      • First Look

      First Look: Nov. 3

      listed and unlisted firms from across a wide spectrum of manufacturing and services industries and ownership structures such as state-owned firms, business groups, and private and foreign firms. Detailed... View Details
      Keywords: Martha Lagace
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