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      • October 2009 (Revised August 2014)
      • Case

      Tengion: Bringing Regenerative Medicine to Life

      By: Elie Ofek and Polly Ross Ribatt
      Tengion is a young biotech company that is at the frontier of regenerative medicine—a nascent field that seeks to promote the creation of new cells and tissue to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. In late... View Details
      Keywords: Decision Choices and Conditions; Financial Crisis; Entrepreneurship; Health Care and Treatment; Technological Innovation; Product Launch; Product Development; Research and Development; Biotechnology Industry; United States
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      Ofek, Elie, and Polly Ross Ribatt. "Tengion: Bringing Regenerative Medicine to Life." Harvard Business School Case 510-031, October 2009. (Revised August 2014.)
      • December 2008 (Revised April 2010)
      • Case

      Proteus Biomedical: Making Pigs Fly

      By: Richard G. Hamermesh, Lauren Barley and Ginger Graham
      Proteus is a healthcare start-up that has developed technology to embed electronics for computing and sensing in existing medical devices and drugs. The technology could potentially change the basis of competition in the pharmaceutical industry. The company is... View Details
      Keywords: Business Startups; Entrepreneurship; Technological Innovation; Rights; Negotiation Deal; Business Strategy; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Hamermesh, Richard G., Lauren Barley, and Ginger Graham. "Proteus Biomedical: Making Pigs Fly." Harvard Business School Case 809-051, December 2008. (Revised April 2010.)
      • September 2008
      • Background Note

      Background on the Technology of Molecular Diagnostics

      By: Regina E. Herzlinger and Jason Sanders
      To be used as background reading for the "EXACT Sciences Corp.: Commercializing a Diagnostic Test" and "Diagnostic Genomics" cases, HBS nos. 308-090 and 309-040. View Details
      Keywords: Health Testing and Trials; Technology; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Herzlinger, Regina E., and Jason Sanders. "Background on the Technology of Molecular Diagnostics." Harvard Business School Background Note 309-050, September 2008.
      • September 2008 (Revised March 2020)
      • Supplement

      Medtronic: Patient Management Initiative (B)

      By: Regina E. Herzlinger
      The (B) case provides the denouement to the (A) case about Medtronic's introduction of the Chronicle and remote monitoring business. View Details
      Keywords: Health Care and Treatment; Measurement and Metrics; Information Technology; Competitive Strategy; Medical Devices and Supplies Industry
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      Herzlinger, Regina E. "Medtronic: Patient Management Initiative (B)." Harvard Business School Supplement 309-064, September 2008. (Revised March 2020.)
      • November 2007
      • Case

      Center for Integration of Medicine and Innovative Technology (CIMIT)

      By: H. Kent Bowen and Courtney Purrington
      Translating innovative ideas form the clinician to the patient remains a major problem in the field of medicine. Dr. John Parrish and colleagues created an organization (CIMIT) that brings the technical, financial, and administrative resources to these innovative... View Details
      Keywords: Financing and Loans; Innovation and Invention; Technological Innovation; Resource Allocation; Alliances; Research and Development; Health Industry; Service Industry
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      Bowen, H. Kent, and Courtney Purrington. "Center for Integration of Medicine and Innovative Technology (CIMIT)." Harvard Business School Case 608-036, November 2007.
      • June 2007 (Revised October 2007)
      • Case

      Information Technology and Clinical Operations at Beth Israel Deaconess Medical Center

      By: Richard M.J. Bohmer, F. Warren McFarlan and Julia Rose Adler-Milstein
      Describes the history of clinical computing at Boston's Beth Israel Hospital and the development, since the 1996 merger to form the Beth Israel Deaconess Medical Center, of an information system designed to support the delivery of patient care. The hospitals' CIO, John... View Details
      Keywords: Health Care and Treatment; Product Design; Service Delivery; Information Technology; Applications and Software; Health Industry; Boston
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      Bohmer, Richard M.J., F. Warren McFarlan, and Julia Rose Adler-Milstein. "Information Technology and Clinical Operations at Beth Israel Deaconess Medical Center." Harvard Business School Case 607-150, June 2007. (Revised October 2007.)
      • November 2006
      • Case

      Brontes Technologies -- 2005

      By: William A. Sahlman and Caroline Perkins
      Describes a set of decisions confronting the founders of a company developing a new device for taking three-dimensional pictures of teeth in order to improve dental outcomes. The company needs more money and must choose between raising new equity capital from a venture... View Details
      Keywords: Borrowing and Debt; Business Startups; Medical Devices and Supplies Industry
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      Sahlman, William A., and Caroline Perkins. "Brontes Technologies -- 2005." Harvard Business School Case 807-101, November 2006.
      • September 2006 (Revised April 2007)
      • Case

      Medtronic Vision 2010

      By: Lynda M. Applegate
      Describes the company's year-long efforts to transition from a medical device company selling products to physicians for use with patients suffering chronic end-stage disease, to a medical technology company providing life-long solutions for people with chronic... View Details
      Keywords: Business Plan; Transition; Decision Choices and Conditions; Corporate Entrepreneurship; Financial Management; Financing and Loans; Health Care and Treatment; Innovation and Invention; Strategic Planning; Health Industry
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      Applegate, Lynda M. "Medtronic Vision 2010." Harvard Business School Case 807-051, September 2006. (Revised April 2007.)
      • April 2006
      • Case

      Medical Innovation Beyond MedStar: Mobilizing for National Impact

      By: Rosabeth M. Kanter, Ryan Raffaelli and Michelle Heskett
      Dr. Craig Feied, director of MedStar Health's Medical Informatics programs, wanted his innovations to influence national health care. Since joining Washington Hospital Center's Emergency Department in 1995 with Dr. Mark Smith, their information system had become the... View Details
      Keywords: Collaborative Innovation and Invention; Innovation Strategy; Technological Innovation; Policy; Government and Politics; Innovation and Management; Projects; Corporate Social Responsibility and Impact; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry; Washington (state, US)
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      Kanter, Rosabeth M., Ryan Raffaelli, and Michelle Heskett. "Medical Innovation Beyond MedStar: Mobilizing for National Impact." Harvard Business School Case 306-096, April 2006.
      • January 2006 (Revised April 2007)
      • Case

      General Electric Healthcare, 2006

      By: Tarun Khanna and Elizabeth Raabe
      In January 2006, Joe Hogan, head of General Electric (GE) Healthcare Technologies, prepared to step into William Castell's shoes as CEO of GE Healthcare, the world's leading manufacturer of diagnostic imaging equipment. In 2004, former CEO Jeff Immelt acquired Amersham... View Details
      Keywords: Corporate Entrepreneurship; Cost vs Benefits; Growth and Development Strategy; Mergers and Acquisitions; Machinery and Machining; Global Range; Multinational Firms and Management; Product Design; Technological Innovation; Expansion; Value Creation; Business Subsidiaries; Medical Devices and Supplies Industry; Medical Devices and Supplies Industry
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      Khanna, Tarun, and Elizabeth Raabe. "General Electric Healthcare, 2006." Harvard Business School Case 706-478, January 2006. (Revised April 2007.)
      • December 2005 (Revised October 2013)
      • Case

      Fred Khosravi and AccessClosure (A)

      By: Richard Hamermesh and Liz Kind
      Fred Khosravi is a serial medical device entrepreneur. In his latest venture, he must decide whether to sell now or continue to develop his current product and whether to market it, sell the company, or IPO. View Details
      Keywords: Negotiation; Medical Devices; Venture Capital; Life Sciences; Health Care Industry; Healthcare Technology; Healthcare Ventures; Business Startups; Decision Choices and Conditions; Entrepreneurship; Growth and Development Strategy; Medical Devices and Supplies Industry; United States
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      Hamermesh, Richard, and Liz Kind. "Fred Khosravi and AccessClosure (A)." Harvard Business School Case 806-044, December 2005. (Revised October 2013.)
      • June 2005 (Revised July 2006)
      • Background Note

      Note on the Convergence Between Genomics & Information Technology

      By: David B. Yoffie, Dharmesh M Mehta and Rachel Sha
      Focuses on the convergence between the genomics and semiconductor industries, in particular organ printing, DNA computing, biomolecular sensory networks, and DNA microarrays. Explains what this newly converged world looks like based on current research and findings in... View Details
      Keywords: Genetics; Information Technology; Business Model; Disruptive Innovation; Information Technology Industry; Information Technology Industry; Information Technology Industry; Information Technology Industry
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      Yoffie, David B., Dharmesh M Mehta, and Rachel Sha. "Note on the Convergence Between Genomics & Information Technology." Harvard Business School Background Note 705-500, June 2005. (Revised July 2006.)
      • July 2004 (Revised April 2005)
      • Teaching Note

      MedSource Technologies (TN)

      By: Robert S. Huckman
      Teaching Note to (9-603-081). View Details
      Keywords: Medical Devices and Supplies Industry
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      Huckman, Robert S. "MedSource Technologies (TN)." Harvard Business School Teaching Note 605-014, July 2004. (Revised April 2005.)
      • August 2003 (Revised August 2006)
      • Case

      New Sector Alliance (A): An Entry into Health Care?

      By: Regina E. Herzlinger, Stacy Smollin Schwartz and Jeffrey Cronin
      Describes the structure of the U.S. health care system and presents a study of a nonprofit consulting firm that hopes to enter the health care system. Includes descriptions of hospitals, doctors, insurers, medical technology providers, medical devices, pharmaceuticals,... View Details
      Keywords: Health; Health Care and Treatment; Health Disorders; Nonprofit Organizations; Health Industry; United States
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      Herzlinger, Regina E., Stacy Smollin Schwartz, and Jeffrey Cronin. "New Sector Alliance (A): An Entry into Health Care?" Harvard Business School Case 304-004, August 2003. (Revised August 2006.)
      • March 2003
      • Article

      Technological Development and Medical Productivity: The Diffusion of Angioplasty in New York State

      By: David M. Cutler and Robert S. Huckman
      A puzzling feature of many medical innovations is that they simultaneously appear to reduce unit costs and increase total costs. We consider this phenomenon by examining the diffusion of percutaneous transluminal coronary angioplasty (PTCA)—a treatment for coronary... View Details
      Keywords: Innovation and Invention; Cost; Health Care and Treatment; Health Disorders; Performance Improvement; Product; New York (state, US)
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      Cutler, David M., and Robert S. Huckman. "Technological Development and Medical Productivity: The Diffusion of Angioplasty in New York State." Journal of Health Economics 22, no. 2 (March 2003): 187–217.
      • November 2002 (Revised June 2003)
      • Case

      Corning, Inc.: Technology Strategy in 2003

      By: Rebecca Henderson
      Corning, Inc. has a 150-year history of building a strategy around innovation. Founded as a glass manufacturer in 1851, the company quickly established itself as a maker of specialty glass products and over the next 100 years diversified into light bulbs, television,... View Details
      Keywords: Information Technology; Strategy; Innovation Strategy; Situation or Environment; Research and Development; Consumer Products Industry; United States
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      Henderson, Rebecca. "Corning, Inc.: Technology Strategy in 2003." Harvard Business School Case 703-440, November 2002. (Revised June 2003.)
      • November 2002 (Revised August 2003)
      • Case

      MedSource Technologies

      By: Robert S. Huckman
      Considers the issues facing Richard Effress, MedSource's chairman and CEO, as the firm approaches the Precision Cut project--the first test of MedSource's capabilities as an integrated, contract manufacturer in the medical device industry. MedSource Technologies was... View Details
      Keywords: Product Development; Production; Mergers and Acquisitions; Product Design; Supply Chain Management; Management Teams; Medical Devices and Supplies Industry; United States
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      Huckman, Robert S. "MedSource Technologies." Harvard Business School Case 603-081, November 2002. (Revised August 2003.)
      • September 2002
      • Case

      Align Technology, Inc.: Matching Manufacturing Capacity to Sales Demand

      By: H. Kent Bowen and Jonathan P Groberg
      Align Technology is a four-year-old medical products company that has invented a new product requiring new manufacturing processes. Demand for the new product has grown more slowly than initial forecasts predicted, and the cost structure is preventing the company from... View Details
      Keywords: Health Care and Treatment; Collaborative Innovation and Invention; Problems and Challenges; Product; Forecasting and Prediction; Marketing Strategy; Sales; Demand and Consumers; Production; Health Industry
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      Bowen, H. Kent, and Jonathan P Groberg. "Align Technology, Inc.: Matching Manufacturing Capacity to Sales Demand." Harvard Business School Case 603-058, September 2002.
      • July 2002 (Revised August 2002)
      • Case

      Washington Hospital Center (A): Rescuing Emergency Medicine

      By: Rosabeth M. Kanter and Michelle Heskett
      Dr. Craig Feied and Dr. Mark Smith, recruited to turn around the Washington Hospital Center Emergency Department, prepare to roll out their most revolutionary change yet--an information system that could radically improve the practice of emergency medicine. A review of... View Details
      Keywords: Change Management; Health Care and Treatment; Nonprofit Organizations; Medical Specialties; Organizational Culture; Crisis Management; Technological Innovation; Higher Education; Health Industry; District of Columbia
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      Kanter, Rosabeth M., and Michelle Heskett. "Washington Hospital Center (A): Rescuing Emergency Medicine." Harvard Business School Case 303-019, July 2002. (Revised August 2002.)
      • July 2002 (Revised August 2002)
      • Case

      Washington Hospital Center (B): The Power of Insight

      By: Rosabeth M. Kanter and Michelle Heskett
      Dr. Craig Feied considers how to take a major technical innovation beyond his own department into a large hospital system. Reviews how proprietary information systems became indispensable in the department of emergency medicine and what it took to introduce the change... View Details
      Keywords: Change Management; Health Care and Treatment; Nonprofit Organizations; Medical Specialties; Organizational Culture; Crisis Management; Technological Innovation; Higher Education; Adoption; Health Industry; District of Columbia
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      Kanter, Rosabeth M., and Michelle Heskett. "Washington Hospital Center (B): The Power of Insight." Harvard Business School Case 303-020, July 2002. (Revised August 2002.)
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