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      • July 2023
      • Article

      Design and Analysis of Switchback Experiments

      By: Iavor I Bojinov, David Simchi-Levi and Jinglong Zhao
      In switchback experiments, a firm sequentially exposes an experimental unit to a random treatment, measures its response, and repeats the procedure for several periods to determine which treatment leads to the best outcome. Although practitioners have widely adopted... View Details
      Keywords: Switchback Experiments; Design; Analysis; Mathematical Methods
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      Bojinov, Iavor I., David Simchi-Levi, and Jinglong Zhao. "Design and Analysis of Switchback Experiments." Management Science 69, no. 7 (July 2023): 3759–3777.
      • Summer 2023
      • Article

      Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?

      By: Eric Barrette, Leemore S. Dafny and Karen Shen
      Even among commercially insured individuals, opioid use disorder is undertreated in the United States: nearly half receive no treatment within six months of a new diagnosis. Using a difference-in-differences specification exploiting the extension of insurance parity... View Details
      Keywords: Opioid Treatment; Medication-assisted Treatment; Substance Use Disorder; Private Insurance; Insurance; Health Care and Treatment
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      Barrette, Eric, Leemore S. Dafny, and Karen Shen. "Do Policies to Increase Access to Treatment for Opioid Use Disorder Work?" American Journal of Health Economics 9, no. 3 (Summer 2023): 297–330.
      • July 2023
      • Article

      So, Who Likes You? Evidence from a Randomized Field Experiment

      By: Ravi Bapna, Edward McFowland III, Probal Mojumder, Jui Ramaprasad and Akhmed Umyarov
      With one-third of marriages in the United States beginning online, online dating platforms have become important curators of the modern social fabric. Prior work on online dating has elicited two critical frictions in the heterosexual dating market. Women, governed by... View Details
      Keywords: Online Dating; Internet and the Web; Analytics and Data Science; Gender; Emotions; Social and Collaborative Networks
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      Bapna, Ravi, Edward McFowland III, Probal Mojumder, Jui Ramaprasad, and Akhmed Umyarov. "So, Who Likes You? Evidence from a Randomized Field Experiment." Management Science 69, no. 7 (July 2023): 3939–3957.
      • June 2023
      • Supplement

      Roche: ESG and Access to Healthcare

      By: George Serafeim
      In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first ESG investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that... View Details
      Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Pharmaceutical Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
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      Serafeim, George. "Roche: ESG and Access to Healthcare." Harvard Business School Multimedia/Video Supplement 123-713, June 2023.
      • 3 Jun 2023
      • Talk

      Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen

      By: Regina E. Herzlinger
      The crush of patients created by COVID enabled the creation of sites for care outside the traditional hospital, such as retail pharmacies, ambulatory surgery centers, urgent care centers, telemedicine, and wireless sensors. Public policy mirrored these changes by... View Details
      Keywords: Policy; Health Pandemics; Health Care and Treatment; Innovation and Invention; Health Industry; Insurance Industry
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      Herzlinger, Regina E. "Health Care Innovation Opportunities Created by COVID-19 and How to Make Them Happen." Harvard Business School Alumni Reunion, Boston, MA, June 3, 2023. (Link to cases described in this talk.)
      • June 2023
      • Article

      Do Job Seekers Value Diversity Information? Evidence from a Field Experiment and Human Capital Disclosures

      By: Jung Ho Choi, Joseph Pacelli, Kristina M. Rennekamp and Sorabh Tomar
      We examine how information about the diversity of a potential employer's workforce affects individuals’ job-seeking behavior. We embed a field experiment in job recommendation emails from a leading career advice agency in the U.S. The experimental treatment involves... View Details
      Keywords: Diversity; Job Search; Employees; Corporate Disclosure
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      Choi, Jung Ho, Joseph Pacelli, Kristina M. Rennekamp, and Sorabh Tomar. "Do Job Seekers Value Diversity Information? Evidence from a Field Experiment and Human Capital Disclosures." Journal of Accounting Research 61, no. 3 (June 2023): 695–735.
      • June 2023
      • Teaching Note

      From Cradle to Heaven: Taikang Insurance Group

      By: William C. Kirby and Noah B. Truwit
      Teaching Note for HBS Case No. 320-088. The case explores the rise of Taikang Insurance Group and its quest to be a leader of one of China's fastest-growing industries. Due to China's underdeveloped social welfare state, Taikang saw an opportunity for the private... View Details
      Keywords: Health Care and Treatment; Government and Politics; Health Industry; China
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      Kirby, William C., and Noah B. Truwit. "From Cradle to Heaven: Taikang Insurance Group." Harvard Business School Teaching Note 323-126, June 2023.
      • June 2023
      • Case

      Verve Therapeutics: Taking DNA Editing to Heart

      By: Shikhar Ghosh and Shweta Bagai
      Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
      Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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      Ghosh, Shikhar, and Shweta Bagai. "Verve Therapeutics: Taking DNA Editing to Heart." Harvard Business School Case 823-113, June 2023.
      • 2023
      • Article

      Exploiting Discovered Regression Discontinuities to Debias Conditioned-on-observable Estimators

      By: Benjamin Jakubowski, Siram Somanchi, Edward McFowland III and Daniel B. Neill
      Regression discontinuity (RD) designs are widely used to estimate causal effects in the absence of a randomized experiment. However, standard approaches to RD analysis face two significant limitations. First, they require a priori knowledge of discontinuities in... View Details
      Keywords: Regression Discontinuity Design; Analytics and Data Science; AI and Machine Learning
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      Jakubowski, Benjamin, Siram Somanchi, Edward McFowland III, and Daniel B. Neill. "Exploiting Discovered Regression Discontinuities to Debias Conditioned-on-observable Estimators." Journal of Machine Learning Research 24, no. 133 (2023): 1–57.
      • May 2023 (Revised June 2023)
      • Case

      Novartis (A): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Leadership; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (A): Reimagining Medicine." Harvard Business School Case 723-443, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (B): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (B): Reimagining Medicine." Harvard Business School Supplement 723-444, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (C): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (C): Reimagining Medicine." Harvard Business School Supplement 723-445, May 2023. (Revised June 2023.)
      • May 2023
      • Article

      Decarbonizing Health Care: Engaging Leaders in Change

      By: Vivian S. Lee, Kathy Gerwig, Emily Hough, Kedar Mate, Robert Biggio and Robert S. Kaplan
      Health care leaders are often surprised to learn that their operations contribute significantly to a warming climate. In addition to their roles as responders to and victims of extreme weather events, health care organizations have an obligation to reduce... View Details
      Keywords: Health Care; Decarbonization; Carbon Emissions; Net-zero Emissions; Climate Change; Health Care and Treatment; Health Industry
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      Lee, Vivian S., Kathy Gerwig, Emily Hough, Kedar Mate, Robert Biggio, and Robert S. Kaplan. "Decarbonizing Health Care: Engaging Leaders in Change." NEJM Catalyst Innovations in Care Delivery 4, no. 5 (May 2023).
      • April 2023 (Revised January 2024)
      • Background Note

      Note on Healthcare in Ghana

      By: Regina E. Herzlinger and Ben Creo
      This note provides an overview of the healthcare system in Ghana. It discusses the public and private sector as well as traditional medical practice. It also discusses the country’s pharmaceutical industry. It is recommended as a companion to Professor Regina... View Details
      Keywords: Africa; Pharmaceutical Companies; Pharmacy Benefit Manager; Health Care; Health Care Costs; Health Care Delivery; Health Care Entrepreneurship; Telehealth; Health Equity; Governing Rules, Regulations, and Reforms; Health Care and Treatment; Business and Government Relations; Health Industry; Pharmaceutical Industry; Ghana
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      Herzlinger, Regina E., and Ben Creo. "Note on Healthcare in Ghana." Harvard Business School Background Note 323-112, April 2023. (Revised January 2024.)
      • April 5, 2023
      • Article

      We Need an Operation Warp Speed for Long COVID

      By: Esther K. Choo and Scott Duke Kominers
      With millions of people affected and at least $1 trillion of economic value at stake, long COVID is our next national health emergency. View Details
      Keywords: COVID; COVID-19; COVID-19 Pandemic; Scientific Research; Policy; Health Policy; Innovation; Science; Public Finance; Public Health; Health Disorders; Health Care and Treatment; Human Capital
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      Choo, Esther K., and Scott Duke Kominers. "We Need an Operation Warp Speed for Long COVID." Scientific American (website) (April 5, 2023).
      • March–April 2023
      • Article

      Pricing for Heterogeneous Products: Analytics for Ticket Reselling

      By: Michael Alley, Max Biggs, Rim Hariss, Charles Herrmann, Michael Lingzhi Li and Georgia Perakis
      Problem definition: We present a data-driven study of the secondary ticket market. In particular, we are primarily concerned with accurately estimating price sensitivity for listed tickets. In this setting, there are many issues including endogeneity, heterogeneity in... View Details
      Keywords: Price; Demand and Consumers; AI and Machine Learning; Investment Return; Entertainment and Recreation Industry; Sports Industry
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      Alley, Michael, Max Biggs, Rim Hariss, Charles Herrmann, Michael Lingzhi Li, and Georgia Perakis. "Pricing for Heterogeneous Products: Analytics for Ticket Reselling." Manufacturing & Service Operations Management 25, no. 2 (March–April 2023): 409–426.
      • March 2023 (Revised March 2025)
      • Case

      Close Concerns: Diabetes Research and Advocacy

      By: Regina Herzlinger and Brian L. Walker
      Diagnosed with diabetes at the age of 18, Kelly Close understood the importance of balancing consistency and iteration. This principle had also informed her professional work, which started with a rapid promotion from financial analyst at Goldman Sachs to an analyst... View Details
      Keywords: Diabetes; Health; Health Care; Health Care And Treatment; Health Care Outcomes; Health Care Industry; Knowledge Dissemination; Outcome or Result; Equality and Inequality; Business Model; Entrepreneurship
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      Herzlinger, Regina, and Brian L. Walker. "Close Concerns: Diabetes Research and Advocacy." Harvard Business School Case 323-047, March 2023. (Revised March 2025.)
      • March 2023
      • Case

      Roche: ESG and Access to Healthcare

      By: George Serafeim, Susanna Gallani and Benjamin Maletta
      In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first ESG investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that... View Details
      Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Pharmaceutical Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
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      Serafeim, George, Susanna Gallani, and Benjamin Maletta. "Roche: ESG and Access to Healthcare." Harvard Business School Case 123-075, March 2023.
      • 2023
      • Article

      Comparison of COVID-19 Hospitalization Costs across Care Pathways: A Patient-level Time-driven Activity-based Costing Analysis in a Brazilian Hospital

      By: Ricardo Bertoglio Cardoso, Miriam Allein Zago Marcolino, Milena Soriano Marcolino, Camila Felix Fortis, Leila Beltrami Moreira, Ana Paula Coutinho, Nadine Oliveira Clausell, Junaid Nabi, Robert S. Kaplan, Ana Paula Beck da Silva Etges and Carisi Anne Polanczyk
      The COVID-19 pandemic raised awareness of the need to better understand where and how patient-level costs are incurred in health care organizations. This study used time-driven activity-based costing to estimate COVID-19 patient-level hospital costs in a Brazilian... View Details
      Keywords: Health Care and Treatment; Cost; Health Industry; Brazil
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      Cardoso, Ricardo Bertoglio, Miriam Allein Zago Marcolino, Milena Soriano Marcolino, Camila Felix Fortis, Leila Beltrami Moreira, Ana Paula Coutinho, Nadine Oliveira Clausell, Junaid Nabi, Robert S. Kaplan, Ana Paula Beck da Silva Etges, and Carisi Anne Polanczyk. "Comparison of COVID-19 Hospitalization Costs across Care Pathways: A Patient-level Time-driven Activity-based Costing Analysis in a Brazilian Hospital." BMC Health Services Research 23, no. 198 (2023).
      • February 2023
      • Teaching Note

      Bangladesh: Into the Maelstrom

      By: Reshmaan Hussam, Sophus A. Reinert and Jaya Y. Wen
      In the fall of 2018, Rohima Begum considered her options as the small island, or “char,” on which her family’s house rested slowly but inescapably eroded into the mighty Brahmaputra River in northern Bangladesh. Should she move to another island or into the city on the... View Details
      Keywords: Climate Change; Geographic Location; Bangladesh
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      Hussam, Reshmaan, Sophus A. Reinert, and Jaya Y. Wen. "Bangladesh: Into the Maelstrom." Harvard Business School Teaching Note 723-050, February 2023.
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