Publications

March 2008 (Revised June 2008)
Case

The Broad Institute: Applying the Power of Genomics to Medicine

By: Vicki L. Sato and Rachel Gordon

In June 2003, Harvard University and MIT announced an unprecedented partnership to create a biomedical institute, The Broad Institute. The culture of the Broad centered on science, and those involved considered it to be at the edge of the scientific frontier. In just... View Details

Keywords: Education; Health Care and Treatment; Innovation Leadership; Growth and Development Strategy; Organizational Culture; Partners and Partnerships; Research and Development; Genetics

2024
Working Paper

Bootstrap Diagnostics for Irregular Estimators

By: Isaiah Andrews and Jesse M. Shapiro

Empirical researchers frequently rely on normal approximations in order to summarize and communicate uncertainty about their findings to their scientific audience. When such approximations are unreliable, they can lead the audience to make misguided decisions. We... View Details

Keywords: Mathematical Methods; Decision Choices and Conditions

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March 1, 2022
Article

Widespread Use of National Academies Consensus Reports by the American Public

By: Diana Hicks, Matteo Zullo, Ameet Doshi and Omar Isaac Asensio

In seeking to understand how to protect the public information sphere from corruption, researchers understandably focus on dysfunction. However, parts of the public information ecosystem function very well, and understanding this as well will help in protecting and... View Details

Keywords: Reports; Surveys; AI and Machine Learning; Knowledge Dissemination; Knowledge Use and Leverage

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20 Sep 2011
First Look

First Look: September 20

on Cancer: Integrative Research Centers at the Dana Farber Cancer Institute Heidi K. Gardner, Edo Bedzra, and Shereef M. ElnahalHarvard Business School Case 412-029 Dr. Barrett Rollins, chief scientific... View Details

Keywords: Sean Silverthorne

September 2017
Case

Sensing (and Monetizing) Happiness at Hitachi

By: Ethan Bernstein and Stephanie Marton

Inspired by research linking happiness and productivity, Hitachi had invested in developing new “people analytics” technologies to help companies increase employee happiness. Hitachi had begun manufacturing high-tech badges that quantify a wearer’s activity patterns.... View Details

Keywords: People Analytics; Japan; Sociometers; Wearables; Interpersonal Communication; Human Resources; Happiness; Technology Industry; Japan

March 2008
Case

Novartis AG: Science-Based Business

By: H. Kent Bowen and Courtney Purrington

Novartis is a science-based drug company, which has important implications for its business strategy. It is one of the largest pharmaceutical companies in the world with over $38B in sales in 2007. Pharmaceuticals account for slightly over $24B of that total. In 2007,... View Details

Keywords: Innovation and Invention; Resource Allocation; Product Development; Partners and Partnerships; Research and Development; Science-Based Business; Pharmaceutical Industry

July 2011 (Revised January 2013)
Case

Digital Microscopy Is Making Me Crazy!

By: Willy Shih

For Carl Zeiss Microimaging, modular hardware and software enabled customers to tailor Zeiss's broad range of microscopy systems hardware and software to meet a wide range of needs from basic scientific research in the biological and medical sciences to clinical... View Details

Keywords: Information Infrastructure; Applications and Software; Corporate Strategy; Disruptive Innovation; Science-Based Business; Management Analysis, Tools, and Techniques; Business Conglomerates; Digital Platforms; Opportunities; Medical Devices and Supplies Industry; Computer Industry

02 Jun 2022
Research & Ideas

Blissful Thinking: When It Comes to Finding Happiness, 'Your Dreams Are Liars'

and a former professional French-horn player, Brooks came to the subject of happiness by way of art. His early research focused on why people produce and consume art and beauty as well as the motives behind human generosity. He discovered... View Details

Keywords: by Dan Morrell

May 2006
Case

A123Systems

By: H. Kent Bowen, Kenneth P Morse and Douglass Cannon

A 123Systems was a young company that was founded on basic materials science research at the Massachusetts Institute of Technology. A co-founder of the company, Yet-Ming Chiang, was a full professor at MIT and served as scientific adviser. Intellectual property based... View Details

Keywords: Intellectual Property; Business Startups; Research and Development; Commercialization; Technological Innovation; Science-Based Business; Product Development; Battery Industry; Electronics Industry; Massachusetts

September 2014
Article

Pollution and Skin: From Epidemiological and Mechanistic Studies to Clinical Implications

By: Jean Krutmann, Wei Liu, Li Li, Xiaochuan Pan, Martha Crawford, Gabrielle Sore and Sophie Seite

In recent years, the health effects associated with air pollution have been intensively studied. Most studies focus on air pollution effects on the lung and the cardiovascular system. More recently, however, epidemiological and mechanistic studies suggest that air... View Details

Keywords: Pollutants; Health Disorders; Medical Specialties

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12 Apr 2022
Research & Ideas

Swiping Right: How Data Helped This Online Dating Site Make More Matches

Their research suggests that transparency on dating sites—as simple as allowing users to see the identity and photos of those who “swiped right” to show their interest—improves engagement for both men and women. Since Match.com launched... View Details

Keywords: by Kara Baskin

March, 2023
Article

Academic Entrepreneurship: Entrepreneurial Advisors and Their Advisees' Outcomes

By: Maria P. Roche

The transfer of complex knowledge and skills is difficult, often requiring intensive interaction and extensive periods of co-working between a mentor and mentee, which is particularly true in apprenticeship-like settings and on-the-job training. This paper studies a... View Details

Keywords: Entrepreneurship; Higher Education; Training; Personal Development and Career; Knowledge Dissemination

2012
Book

Producing Prosperity: Why America Needs a Manufacturing Renaissance

By: Gary P. Pisano and Willy Shih

For years—even decades—in response to intensifying global competition, American companies decided to outsource their manufacturing operations in order to reduce costs. But we are now seeing the alarming long-term effect of those choices: in many cases, once... View Details

Keywords: Job Cuts and Outsourcing; Production; Competitive Advantage; Transformation; Innovation and Invention; Manufacturing Industry; United States

2023
Working Paper

Mapping Organizational-Level Networks Using Individual-Level Connections: Evidence from Online Professional Networks

By: Shelley Xin Li, Frank Nagle and Aner Zhou

Organization-level networks facilitate the flow of information and business activities in the economy. Prior research relies solely on high-level connections to measure these networks. Therefore, to understand the role of employee connections at all job levels in... View Details

Keywords: Networks; Value; Social and Collaborative Networks; Innovation and Invention; Knowledge Sharing; Employees; Social Media

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06 Jun 2016
Research & Ideas

Skills and Behaviors that Make Entrepreneurs Successful

financed them—declared such brick-and-mortar businesses were dinosaurs on their way to extinction. The success of Bluemercury proved the critics wrong. “We’ve always had a hard time being able to identify the skills and behaviors of entrepreneurial leaders” Despite... View Details

Keywords: by HBS Working Knowledge

23 Sep 2015
Research & Ideas

Men Want Powerful Jobs More Than Women Do

New research from Harvard Business School reveals a stark gap in the professional ambitions of men and women. Having surveyed a diverse sample of more than 4,000 men and women, a team of social scientists reports a list of potentially... View Details

Keywords: by Carmen Nobel

July–August 2008
Article

Interview with a Quality Leader: Regina E. Herzlinger on Consumer-Driven Healthcare

By: Regina E. Herzlinger

Regina E. Herzlinger is the Nancy R. McPherson Professor of Business Administration Chair at the Harvard Business School, Cambridge, MA. She received her bachelor's degree from MIT and her doctorate from the Harvard Business School The first woman to be tenured and... View Details

Keywords: Consumer-driven Health Care; Health Care and Treatment; Health Industry

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