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05 Jun 2006
Research & Ideas

Using Competition to Reform Healthcare

not performing the surgery at all, and treating the case in a different way. Value may be still greater if preventive care and advice is provided over time so that little or no treatment is needed at all. The relevant business in View Details

Keywords: by Michael E. Porter; Health

November 2017
Case

The 'Wonder Drug' That Killed Babies

By: Joshua Lev Krieger, Tom Nicholas and Matthew Preble

In the early 1960s, a popular drug taken by patients worldwide for a range of maladies was found to cause severe birth defects and other health problems in babies born to mothers who had taken it during a certain stage of fetal development. As many as 10,000 children... View Details

Keywords: Regulation; Business and Government Relations; Business and Community Relations; Business and Stakeholder Relations; Product Marketing; Corporate Social Responsibility and Impact; Business History; Health; Government Legislation; Corporate Accountability; Ethics; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; Public Administration Industry; United States; United Kingdom; Australia; Germany; Europe

2024
Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms

July 2016
Article

Economic Implications of the Society for Assisted Reproductive Technology Embryo Transfer Guidelines: Healthcare Dollars Saved by Reducing Iatrogenic Triplets

By: Malinda S. Lee, Brady T. Evans, Ariel Dora Stern and Mark D. Hornstein

Objective: To estimate the national cost savings resulting from reductions in higher-order multiple (HOM) live births (defined as three or more fetuses), following the initial publication of the Society for Assisted Reproductive Technology (SART) guidelines on ET in... View Details

Keywords: Information Technology; Cost Management; Health Care and Treatment; Health Industry

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January 2007 (Revised December 2007)
Case

PSI: Social Marketing Clean Water

By: V. Kasturi Rangan, Nava Ashraf and Marie Bell

Senior management at PSI, arguably the world's largest and most successful social marketer with impressive achievements in the field of family planning, HIV/AIDS, and malaria prevention must determine what to do about their slow-to-take-off clean water initiative.... View Details

Keywords: Investment Funds; Health Care and Treatment; Social Marketing; Natural Environment; Social Enterprise; Business Strategy

23 Mar 2003
Research & Ideas

AIDS in Africa—What’s the Solution?

$10 behind health care, there's a problem." Dr. Pride Chigwedere, an Oak Foundation Research Fellow at the Harvard AIDS Institute who worked as a physician in Zimbabwe, said the policy issues begin with difficulties designing View Details

Keywords: by Julie Jette

2022
Working Paper

THEMIS: A Framework for Cost-Benefit Analysis of COVID-19 Non-Pharmaceutical Interventions

By: Dimitris Bertsimas, Michael Lingzhi Li and Saksham Soni

Since December 2019, the world has been ravaged by the COVID-19 pandemic, with over 150 million confirmed cases and 3 million confirmed deaths worldwide. To combat the spread of COVID-19, governments have issued unprecedented non-pharmaceutical interventions (NPIs),... View Details

Keywords: COVID-19; Health Pandemics; Policy; Framework; Cost vs Benefits; Outcome or Result; United States; Germany; Brazil; Singapore; Spain

December 24, 2020
Article

How Businesses Can Find “Hidden Workers”

By: Joseph B. Fuller, Manjari Raman, Eva Sage-Gavin and Ladan Davarzani

Even before the COVID-19 pandemic, low- and middle-skill workers struggled to find and retain steady work. Now, many of these workers are considered “essential,” while many others are unemployed and struggling to find work. As the pandemic eases throughout 2021,... View Details

Keywords: Health Pandemics; Employees; Selection and Staffing

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September 2002
Case

Align Technology, Inc.: Matching Manufacturing Capacity to Sales Demand

By: H. Kent Bowen and Jonathan P Groberg

Align Technology is a four-year-old medical products company that has invented a new product requiring new manufacturing processes. Demand for the new product has grown more slowly than initial forecasts predicted, and the cost structure is preventing the company from... View Details

Keywords: Health Care and Treatment; Collaborative Innovation and Invention; Problems and Challenges; Product; Forecasting and Prediction; Marketing Strategy; Sales; Demand and Consumers; Production; Health Industry

July 2021
Case

A Close Shave at Squire

By: Jeffrey J. Bussgang, Zoë B. Cullen, William R. Kerr, Benjamin N. Roth and Michael Norris

In 2020, just after closing a $34 million Series B financing round, Dave Salvant and Songe LaRon consider how to adjust their business, Squire Technologies, to the new realities posed by the COVID-19 pandemic. Their barbershop technology, including tools to run a shop... View Details

Keywords: Business Startups; Entrepreneurship; Venture Capital; Private Equity; Mobile and Wireless Technology; Applications and Software; Growth and Development Strategy; Health Pandemics; Beauty and Cosmetics Industry; Technology Industry; New York (city, NY); San Francisco

October 2022
Case

Afrigen Biologics: Vaccines for the Global South

By: Debora L. Spar and Julia Comeau

The majority of vaccines used on the continent of Africa (99%) are produced offshore. This makes African nations reliant on the West for major health care needs, a problem which was exacerbated by the COVID-19 pandemic. Afrigen Biologics (in partnership with the WHO)... View Details

Keywords: Vaccination; Vaccine; mRNA; COVID; COVID-19; Inequity; Hub-and-spoke; Health Care and Treatment; Health Pandemics; Production; Social Issues; Business and Government Relations; South Africa; Africa

21 May 2012
Research & Ideas

OSHA Inspections: Protecting Employees or Killing Jobs?

With an election looming and the economy continuing to struggle, the effectiveness of government regulation has become a political football. While advocates hold regulations up as necessary to protect public health and safety, critics see... View Details

Keywords: by Michael Blanding

June 2013
Article

Unconscious Thought Reduces Intrusion Development: A Replication and Extension

By: Julie Krans, Dorte Janecko and Maarten W. Bos

Background and Objectives: Intrusive images after a traumatic event, a hallmark feature of post-traumatic stress disorder, are suggested to develop because the trauma memory is disorganized and not integrated into autobiographical memory. Unconscious Thought... View Details

Keywords: Health Disorders; Cognition and Thinking

January–February 2023
Article

Data-Driven COVID-19 Vaccine Development for Janssen

By: Dimitris Bertsimas, Michael Lingzhi Li, Xinggang Liu, Jennings Xu and Najat Khan

The COVID-19 pandemic has spurred extensive vaccine research worldwide. One crucial part of vaccine development is the phase III clinical trial that assesses the vaccine for safety and efficacy in the prevention of COVID-19. In this work, we enumerate the first... View Details

Keywords: COVID-19; Health Testing and Trials; Forecasting and Prediction; AI and Machine Learning; Research; Pharmaceutical Industry

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2021
Article

Fair Influence Maximization: A Welfare Optimization Approach

By: Aida Rahmattalabi, Shahin Jabbari, Himabindu Lakkaraju, Phebe Vayanos, Max Izenberg, Ryan Brown, Eric Rice and Milind Tambe

Several behavioral, social, and public health interventions, such as suicide/HIV prevention or community preparedness against natural disasters, leverage social network information to maximize outreach. Algorithmic influence maximization techniques have been proposed... View Details

November 1998
Case

Wegmans Food Markets: Diabetes Counseling

By: Ray A. Goldberg, David E. Bell and Ann Leamon

Danny Wegman, president of Wegmans Food Markets, is trying to decide how to evaluate the success of a nutrition-counseling program for diabetics, and whether and how to expand the program beyond the two stores currently involved. Wegmans, with 57 stores and $2.3... View Details

Keywords: Performance Evaluation; Expansion; Programs; Human Needs; Financial Management; Health Care and Treatment; Nutrition; Consumer Behavior; Pharmaceutical Industry; Food and Beverage Industry

July 2024
Case

Replika AI: Alleviating Loneliness (A)

By: Shikhar Ghosh and Shweta Bagai

Eugenia Kuyda launched Replika AI in 2017 as an empathetic digital companion to combat loneliness and provide emotional support. The platform surged in popularity during the COVID-19 pandemic, offering non-judgmental support to isolated users. By 2023, Replika boasted... View Details

Keywords: Entrepreneurship; Ethics; Health Pandemics; AI and Machine Learning; Well-being; Technology Industry

August 2024
Case

Pioneering Pain Management: CWC Alliance Combats the Opioid Epidemic

By: Susanna Gallani, Karen L. Sedatole and Sarah Mehta

Set in March 2024, this case is about CWC Alliance (CWC), a nonprofit working to prevent opioid addiction in the U.S. Founder Cammie Wolf Rice launched CWC in 2018 after her son, Christopher Wolf, died of a heroin overdose. Wolf’s dependence on opioids stemmed from a... View Details

Keywords: Health Care and Treatment; Innovation and Invention; Jobs and Positions; Nonprofit Organizations; Expansion; Growth and Development Strategy; Service Delivery; Mission and Purpose; Health Industry; United States; Georgia (state, US); Atlanta

March 2023 (Revised June 2023)
Teaching Note

Ransomware Attack at Springhill Medical Center

By: Suraj Srinivasan and Li-Kuan (Jason) Ni

Teaching Note for HBS Case No. 123-065. In July, 2019, Springhill Medical Center (“SMC”) in Mobile, Alabama fell prey to a malicious ransomware attack that crippled the hospital’s internal network systems and public-facing web page. While the hospital rushed to... View Details

September 2023 (Revised December 2023)
Case

Twiddy & Company: Trust in a Chaotic Environment

By: Sandra J. Sucher, Shalene Gupta and Tom Quinn

Twiddy & Company, known for Southern hospitality rooted in personal interactions, needed to adjust to contactless remote customer service as fear of the contagious virus prevented person-to-person contact. Local elected officials, in a bid to stop tourists from... View Details

Keywords: Trust; Health Pandemics; Organizational Culture; Disruption; Government Legislation; Transportation; Tourism Industry; North Carolina; United States

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