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- All HBS Web (225)
- Faculty Publications (145)
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- June 2020
- Article
Overcoming Barriers to Early Disease Intervention
By: H. Hugo Caicedo, Daniel A. Hashimoto, Julio C. Caicedo, Alex Pentland and Gary P. Pisano
It is widely acknowledged that earlier intervention in many disease processes leads to better patient outcomes and lower treatment costs. To date, most efforts at early disease intervention have focused on "primary prevention" which focuses on preventing diseases in... View Details
Caicedo, H. Hugo, Daniel A. Hashimoto, Julio C. Caicedo, Alex Pentland, and Gary P. Pisano. "Overcoming Barriers to Early Disease Intervention." Nature Biotechnology 38, no. 6 (June 2020).
- November 2024
- Teaching Note
Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams
By: Debora L. Spar and Julia M. Comeau
Teaching Note for HBS Case No. 323-039. In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At... View Details
Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Growth and Development Strategy; Product Development; Pharmaceutical Industry; Medical Devices and Supplies Industry; United States; District of Columbia
- 1994
- Dissertation
Borderline Personality Disorder: Dimension or Category? A Maximum Covariance Analysis
By: William B. Simpson
- February 2006 (Revised February 2009)
- Case
AIDS in Brazil
By: Rohit Deshpande and Ricardo Reisen de Pinho
Abbott Labs has reached an impasse with the Brazilian government in negotiations over the pricing of a new anti-AIDS drug, Kaletra. The Brazilian government threatens compulsory licensing unless Abbott drastically reduces the price of Kaletra. View Details
Keywords: Price; Government and Politics; Health Care and Treatment; Health Disorders; Rights; Negotiation; Business and Government Relations; Pharmaceutical Industry; Brazil
Deshpande, Rohit, and Ricardo Reisen de Pinho. "AIDS in Brazil." Harvard Business School Case 506-062, February 2006. (Revised February 2009.)
- September 1993 (Revised November 1993)
- Supplement
Partnership for a Drug-Free America (B)
By: V. Kasturi Rangan, Diana Chapman Walsh, Barbara Moeykens and Rima E. Rudd
Rangan, V. Kasturi, Diana Chapman Walsh, Barbara Moeykens, and Rima E. Rudd. "Partnership for a Drug-Free America (B)." Harvard Business School Supplement 594-029, September 1993. (Revised November 1993.)
- March 1990 (Revised March 1992)
- Supplement
New York Against AIDS (B): Backlash to the Advertising Campaign
By: V. Kasturi Rangan and Sohel Karim
Provides a follow-up to the (A) case. View Details
Rangan, V. Kasturi, and Sohel Karim. "New York Against AIDS (B): Backlash to the Advertising Campaign." Harvard Business School Supplement 590-037, March 1990. (Revised March 1992.)
- 2021
- Working Paper
Kidney Exchange: An Operations Perspective
By: Itai Ashlagi and Alvin E. Roth
Many patients in need of a kidney transplant have a willing but incompatible (or poorly matched) living donor. Kidney exchange programs arrange exchanges among such patient-donor pairs, in cycles and chains of exchange, so each patient receives a compatible kidney.... View Details
Ashlagi, Itai, and Alvin E. Roth. "Kidney Exchange: An Operations Perspective." NBER Working Paper Series, No. 28500, February 2021.
- August 21, 2018
- Article
Patient–Physician Gender Concordance and Increased Mortality Among Female Heart Attack Patients
By: Brad Greenwood, Seth Carnahan and Laura Huang
We examine patient gender disparities in survival rates following acute myocardial infarctions (i.e., heart attacks) based on the gender of the treating physician. Using a census of heart attack patients admitted to Florida hospitals between 1991 and 2010, we find... View Details
Greenwood, Brad, Seth Carnahan, and Laura Huang. "Patient–Physician Gender Concordance and Increased Mortality Among Female Heart Attack Patients." Proceedings of the National Academy of Sciences 115, no. 34 (August 21, 2018).
- 01 Oct 2024
- Cold Call Podcast
Choosing Passion: A Founder’s Mission to Meet a Need for Obesity Care
- June 2013
- Article
Unconscious Thought Reduces Intrusion Development: A Replication and Extension
By: Julie Krans, Dorte Janecko and Maarten W. Bos
Background and Objectives: Intrusive images after a traumatic event, a hallmark feature of post-traumatic stress disorder, are suggested to develop because the trauma memory is disorganized and not integrated into autobiographical memory. Unconscious Thought... View Details
Krans, Julie, Dorte Janecko, and Maarten W. Bos. "Unconscious Thought Reduces Intrusion Development: A Replication and Extension." Journal of Behavior Therapy and Experimental Psychiatry 44, no. 2 (June 2013): 179–185.
- September 2021
- Article
Kidney Exchange: An Operations Perspective
By: Itai Ashlagi and Alvin E. Roth
Many patients in need of a kidney transplant have a willing but incompatible (or poorly matched) living donor. Kidney exchange programs arrange exchanges among such patient-donor pairs, in cycles and chains of exchange, so each patient receives a compatible kidney.... View Details
Keywords: Kidney Exchange Programs; Matching; Health Disorders; Health Care and Treatment; Programs; Design
Ashlagi, Itai, and Alvin E. Roth. "Kidney Exchange: An Operations Perspective." Management Science 67, no. 9 (September 2021): 5455–5478.
- May 2016 (Revised March 2020)
- Teaching Note
Cyberdyne: A Leap to the Future
By: Doug J. Chung and Mayuka Yamazaki
Cyberdyne Inc. was a Japanese technology venture founded in 2004 by scientist Yoshiyuki Sankai to commercialize a hybrid assistive limb (HAL). HAL was a robotic exoskeleton system for people who had difficulty walking due to nervous system disabilities resulting from... View Details
- January 2022
- Supplement
Somatus: Value-Based Kidney Care (B)
By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta
Set in early 2020, this (B) case provides an update to the (A) case (no. 622-009) and provides additional context regarding the challenges facing Somatus. View Details
Keywords: Business Startups; Disruption; Entrepreneurship; Health; Health Care and Treatment; Health Disorders; Medical Specialties; Innovation and Invention; Disruptive Innovation; Management; Strategy; Business Strategy; Value; Value Creation; Health Industry; United States; Virginia
Stern, Ariel D., Robert S. Huckman, and Sarah Mehta. "Somatus: Value-Based Kidney Care (B)." Harvard Business School Supplement 622-045, January 2022.
- January 2007
- Article
A Randomized Clinical Trial of EMDR, Fluoxetine and Pill Placebo in the Treatment of PTSD: Treatment Effects and Long-term Maintenance
By: Bessel A. van der Kolk, Joseph Spinazzola, Margaret E. Blaustein, James Hopper, Elizabeth Hopper, Deborah Korn and William B. Simpson
van der Kolk, Bessel A., Joseph Spinazzola, Margaret E. Blaustein, James Hopper, Elizabeth Hopper, Deborah Korn, and William B. Simpson. "A Randomized Clinical Trial of EMDR, Fluoxetine and Pill Placebo in the Treatment of PTSD: Treatment Effects and Long-term Maintenance." Journal of Clinical Psychiatry 68, no. 1 (January 2007).
- November 2017
- Article
A Retrospective Analysis of Hypertension Screening at a Mass Gathering in India: Implications for Non-communicable Disease Control Strategies
By: S. Balsari, P. Vemulapalli, M. Gofine, K. Oswal, R. Merchant, S. Saunik, G. Greenough and T. Khanna
Cardiovascular disease is the leading cause of mortality from noncommunicable diseases (NCD) in India. The government’s National Programme for Prevention and Control of Cancer, Diabetes, Cardiovascular Diseases and Stroke seeks to increase capacity building, screening,... View Details
Balsari, S., P. Vemulapalli, M. Gofine, K. Oswal, R. Merchant, S. Saunik, G. Greenough, and T. Khanna. "A Retrospective Analysis of Hypertension Screening at a Mass Gathering in India: Implications for Non-communicable Disease Control Strategies." Journal of Human Hypertension 31, no. 11 (November 2017): 750–753.
- February 2016 (Revised September 2017)
- Case
Neurotrack and the Alzheimer's Puzzle
By: Richard G. Hamermesh, Liz Kind and Carin-Isabel Knoop
Elli Kaplan founded Neurotrack in 2012 with a breakthrough noninvasive cognitive diagnostics test that will detect Alzheimer's disease in its earliest pre-symptomatic stages. While the company has gained great traction in the three years since it was started, with no... View Details
Keywords: Alzheimer's Disease; Diagnostics; Healthcare; Entrepreneurship; Health Disorders; Science-Based Business; Business Model; Medical Devices and Supplies Industry; United States
Hamermesh, Richard G., Liz Kind, and Carin-Isabel Knoop. "Neurotrack and the Alzheimer's Puzzle." Harvard Business School Case 816-072, February 2016. (Revised September 2017.)
- November 1992 (Revised June 1993)
- Case
The Advertising Council Teen Alcoholism Campaign: Research and Strategy
By: V. Kasturi Rangan and Jayne D. Kramer
Rangan, V. Kasturi, and Jayne D. Kramer. "The Advertising Council Teen Alcoholism Campaign: Research and Strategy." Harvard Business School Case 593-060, November 1992. (Revised June 1993.)
- January 2024 (Revised April 2024)
- Teaching Note
Somatus: Value-Based Kidney Care (A) & (B)
By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta
This teaching note accompanies case no. 622-009 and 622-045 (Somatus: Value-Based Kidney Care, A and B). View Details
- June 2003 (Revised March 2008)
- Case
Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene
By: Regina E. Herzlinger and Marc Aquino
Personalized medicine requires the identification of mutated genes. Schering-Plough's search for the one related to asthma requires finding families with the disease. Examines the industry that helps conduct such research, including contract research organizations. View Details
Keywords: Health Disorders; Research and Development; Genetics; Biotechnology Industry; Pharmaceutical Industry
Herzlinger, Regina E., and Marc Aquino. "Schering-Plough and Genome Therapeutics: Discovering an Asthma Gene." Harvard Business School Case 303-044, June 2003. (Revised March 2008.)
- April 2010
- Teaching Note
Dartmouth-Hitchcock Medical Center: Spine Care (TN)
By: Robert S. Huckman and Michael E. Porter
Teaching Note for [609016]. View Details