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  • 05 Sep 2007
  • First Look

First Look: September 5, 2007

value, or derail deals altogether. Consider, for example, the pharmaceutical company that deadlocked with a supplier over the issue of exclusivity in an ingredient purchase. Believing it was a ploy to raise the price, the drug maker upped... View Details
Keywords: Martha Lagace
  • 15 Nov 2018
  • Book

Can the Global Food Industry Overcome Public Distrust?

JamesBrey Food is the largest segment of the global economy. It is also widely recognized as more critical for human health than any pharmaceutical drug on the planet. But significant changes in the industry are making people lose trust in many institutions involved in... View Details
Keywords: by Sean Silverthorne; Agriculture & Agribusiness
  • 01 Feb 2022
  • Book

Innovation Isn’t Just for Startups: How Big Companies Can Succeed

The EBOs generated revenues that far exceeded the corporation’s acquisitions portfolio in the same period. Carol Kovac led the most successful EBO, IBM Life Sciences. The innovation for this team was to create solutions relevant to a... View Details
Keywords: by Lane Lambert
  • January 2023
  • Case

Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

By: Regina Herzlinger and Brian Walker
What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details
Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
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  • 10 Apr 2014
  • Research & Ideas

John Kotter’s Plan to Accelerate Your Business

other more rational. In a typical organization—from the federal government to a pharmaceutical giant—a hierarchical operational structure meets daily demands through clear reporting relationships and responsibilities, Kotter writes. This... View Details
Keywords: by Kim Girard
  • 2021
  • Working Paper

Regulatory Approval and Expanded Market Size

By: Benjamin Berger, Amitabh Chandra and Craig Garthwaite
Regulatory review of new medicines is often viewed as a hindrance to innovation by increasing the hurdle to bring products to market. However, a more complete accounting of regulation must also account for its potential market expanding effects through quality... View Details
Keywords: New Medicines; Regulatory Approval; Health Care and Treatment; Research and Development; Governing Rules, Regulations, and Reforms; Markets; Expansion; Pharmaceutical Industry
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  • 28 Jul 2008
  • Research & Ideas

Making the Decision to Franchise (or not)

appears to be true when you get a new type of consumer for the same product." In the pharmaceutical industry, for example, selling medicine to both an independent general practitioner and a hospital will... View Details
Keywords: by Julia Hanna; Retail
  • 22 Aug 2022
  • Research & Ideas

Can Amazon Remake Health Care?

Haven, along with JPMorgan Chase and Berkshire Hathaway, which was a naive effort to reform health care. Haven folded in 2021. And in the late 1990s, they tried to buy drugstore.com. So, they’ve been interested in health care for a very long time, but unsuccessful.... View Details
Keywords: by Christina Pazzanese, Harvard Gazette; Health
  • 03 Sep 2013
  • First Look

First Look: September 3

run ads on their blogs and receive 50% of the revenue generated by these ads. After analyzing 4.4 million blog posts, we find that, relative to nonparticipants, popular content increases by about 13 percentage points on participants'... View Details
Keywords: Sean Silverthorne
  • 12 Nov 2013
  • First Look

First Look: November 12

GlaxoSmithKline: Sourcing Complex Professional Services Pharmaceutical company GlaxoSmithKline (GSK) uses an innovative new approach to procuring outside legal counsel: it replaces relationship-based selection and law firms' traditional... View Details
Keywords: Sean Silverthorne
  • 25 Feb 2014
  • First Look

First Look: February 25

Laboratories' Proposed Merger with King Pharmaceutical Perry Capital owns shares in King and, to facilitate approval of the merger, buys shares in Mylan, whilst hedging out its economic exposure to Mylan's share price using derivatives.... View Details
Keywords: Sean Silverthorne
  • 24 Apr 2018
  • First Look

First Look at New Research and Ideas, April 24, 2018

fulfillment that uses centralized inventory management. We ask whether, and if so, how, showrooms benefit the two most basic retail objectives: demand generation and operational efficiency. Using quasi-experimental data on showroom... View Details
Keywords: Sean Silverthorne
  • 12 Jan 2016
  • First Look

January 12, 2016

November–December 2015 Operations Research Active Postmarketing Drug Surveillance for Multiple Adverse Events By: Goh, Joel, Margrét V. Bjarnadóttir, Mohsen Bayati, and Stefanos A. Zenios Abstract—Postmarketing drug surveillance is the process of monitoring the adverse... View Details
Keywords: Carmen Nobel
  • August 2017 (Revised July 2018)
  • Case

MannKind Corporation: Take a Deep Breath, This Time Afrezza Will Work

By: Elie Ofek and Amanda Dai
In June 2014, MannKind Corporation announced that after years of development and billions of dollars in expenses, the FDA had finally approved its drug, Afrezza. MannKind would thus be the only company with an inhalable insulin on the market. As an alternative to... View Details
Keywords: Health Care and Treatment; Product Launch; Product Positioning; Marketing Strategy; Adoption; Pharmaceutical Industry
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  • 05 May 2015
  • First Look

First Look: May 5

causes considerable societal damage, as demonstrated by increasing empirical evidence. Drawing on recent research in moral psychology and behavioral ethics, I examine "moral flexibility," or the common ability to justify one's immoral actions by View Details
Keywords: Carmen Nobel
  • 20 Oct 2011
  • Research & Ideas

Getting the Marketing Mix Right

what is called the Invariant Proportion of Substitution (IPS) property, which implies that the proportion of demand generated by taking business away from a competitor is the same, no matter which marketing activity is used. "These... View Details
Keywords: by Dina Gerdeman
  • 18 Nov 2014
  • First Look

First Look: November 18

and that advertising was critical only in a close election, such as the one in 2004. Interestingly, had the Democrats received more outside advertising in 2004, the election would have ended up in a 269-269 tie. Our findings generate... View Details
Keywords: Sean Silverthorne
  • 15 Dec 2003
  • Research & Ideas

The New Global Business Manager

the general manager—the division head, or the CEO. We used to always talk about the CEO as being the grand strategic architect, sitting on top of the company and defining the priorities and making the strategic investments. Historically,... View Details
Keywords: by Cynthia Churchwell
  • 09 Jan 2007
  • First Look

First Look: January 9, 2007

http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=707413 Teva Pharmaceutical Industries, Ltd. Harvard Business School Case 707-441 Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=707441  ... View Details
Keywords: Martha Lagace
  • 13 Oct 2009
  • Research & Ideas

7 Lessons for Navigating the Storm

CEO Dan Vasella made counterintuitive moves by expanding Novartis's generic drug, vaccines, and consumer health businesses in spending heavily on acquisitions to offer alternatives to patented drugs. Meanwhile, he focused Novartis's View Details
Keywords: by Martha Lagace

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