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  • 27 Feb 2018
  • First Look

First Look at New Research and Ideas, February 27, 2018

prevention-focused questions. We demonstrate that every additional prevention-focused question significantly hinders the entrepreneur's ability to raise capital, fully mediating gender's effect on funding. By experimentally testing an... View Details
Keywords: Sean Silverthorne
  • 20 Nov 2006
  • Research & Ideas

Open Source Science: A New Model for Innovation

unconventional field settings. Their mission was to produce a DNA sequencing test that was cost effective, robust, and operable in extreme field conditions. After several months of effort, the team in consultation with company experts... View Details
Keywords: by Martha Lagace
  • 12 Jan 2016
  • First Look

January 12, 2016

approximation of a fully sequential test for the maximum hazard ratio of the drug over multiple adverse events. A numerical study verifies that our method delivers Type I /II errors that are below... View Details
Keywords: Carmen Nobel
  • 22 Aug 2006
  • First Look

First Look: August 22, 2006

805-067 Molecular Insight has developed a novel biopharmaceutical to detect heart attacks. The company's unique approach to intellectual property protection uses the Hatch Waxman Act and the Orphan Drug Act. The company is struggling to... View Details
Keywords: Martha Lagace
  • 22 May 2020
  • In Practice

Post-COVID Health Care: More Screens, Less Red Tape?

The coronavirus crisis forced health care providers to mobilize in ways few could have predicted six months ago, revealing not only the system’s weaknesses but its profound ingenuity. Within weeks, providers worldwide set up drive-through View Details
Keywords: by Danielle Kost
  • 08 Jan 2008
  • First Look

First Look: January 8, 2008

Abstract We use oil price fluctuations to construct a new instrument to test the impact of transfers from wealthy OPEC nations to their poorer Muslim allies. The instrument identifies plausibly exogenous variation in foreign aid. We... View Details
Keywords: Martha Lagace
  • 18 Apr 2019
  • Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

for Google, etc. AI is already being used as an adjunct to diagnosis in some settings. However, the bar for US Food & Drug Administration approval for a diagnostic test is appropriately high, and... View Details
Keywords: by Martha Lagace; Health; Medical Devices & Supplies
  • 12 Feb 2019
  • First Look

New Research and Ideas, February 12, 2019

Devices: Challenges and Opportunities for U.S. Regulators and Innovators By: Gordon, William J., and Ariel Dora Stern Abstract— Software has become an increasingly important component of medical device technology. Through legislation like the 21st Century Cures Act as... View Details
Keywords: Dina Gerdeman
  • 04 Feb 2014
  • First Look

First Look: February 4

necessary for eliciting effort from those affecting the quality of interdependent teamwork. We consider the role of incentives versus social processes in catalyzing collaboration. We test our hypotheses using a unique data set of 260... View Details
Keywords: Sean Silverthlorne
  • 18 Apr 2017
  • First Look

First Look at New Ideas, April 18

M&A) and Werner Baumann (CFO) have to decide whether to increase the cash portion of their $14.2 billion offer and/or amend the terms of a proposed joint venture (JV) with Merck involving cardiovascular drugs that had been included in... View Details
Keywords: by Sean Silverthorne
  • 24 May 2011
  • First Look

First Look: May 24

perspective that Porter has taken, often as a result of his specific background and prior research interests. The chapter then turns to extensions of these core concepts in Porter's more recent work. A central focus of this work has been the creation of broad-based... View Details
Keywords: Sean Silverthorne
  • 28 Apr 2009
  • First Look

First Look: April 28, 2009

consumer-oriented model for drug development and use has attracted attention in recent years as an alternative to the much-maligned approach of mass-marketing blockbuster drugs. In a parallel development, patients and disease-based... View Details
Keywords: Martha Lagace
  • 28 Jul 2015
  • First Look

First Look: July 28, 2015

country-level factors that limit firms' use of selective disclosure by intensifying scrutiny on them and by diffusing global norms to their headquarters countries. We test our hypotheses using a novel panel dataset of 4,750 public... View Details
Keywords: Carmen Nobel
  • 12 May 2008
  • Research & Ideas

Accounting Information as Political Currency

consistent with established economic theories of accounting. That said, the results suggest that accounting has a broader political role than was previously thought. What surprised us was the significance of our estimates. We were skeptical going in: We weren’t sure... View Details
Keywords: by Martha Lagace
  • 15 Apr 2014
  • First Look

First Look: April 15

from the U.S. Food and Drug Administration (FDA) ordering the company to halt the sale and promotion of its genetic testing kit. The FDA stated that the product was marketed as a diagnostic and preventative... View Details
Keywords: Sean Silverthorne
  • 30 Oct 2007
  • First Look

First Look: October 30, 2007

Changing Context of Pharmaceutical Risk Mitigation Author:Arthur A. Daemmrich Periodical:Pharmacy in History 49, no. 2 (2007): 61-75 Abstract In the wake of Vioxx, Avandia, and other recent prominent cases of drugs found to cause side... View Details
Keywords: Sean Silverthorne
  • 14 Dec 2010
  • First Look

First Look: Dec. 14

empirical implications and possible theoretical extensions. Download the paper: http://www.hbs.edu/research/pdf/11-056.pdf Testing Coleman's Social-Norm Enforcement Mechanism: Evidence from Wikipedia Authors:Mikołaj J. Piskorski and... View Details
Keywords: Sean Silverthorne
  • 15 Jun 2016
  • Research & Ideas

These VC Partners May Make Your Firm Less Innovative

of students, the researchers surmised it may dampen innovation among competitive companies. To test that hypothesis, McDonald, Pahnke, Hallen and Wang looked at close to 200 medical device startups that developed products for minimally... View Details
Keywords: by Michael Blanding; Financial Services; Banking
  • 06 Apr 2015
  • Research & Ideas

After Germanwings, More Attention Needed on Employee Mental Health

chronic work stress, while only 36 percent reported their employers provided adequate support to manage it. According to the National Institute of Mental Health, some 6.7 percent of American adults experience "major depressive disorder; antidepressants are the most... View Details
Keywords: by Michael Blanding; Health; Air Transportation
  • 23 Oct 2018
  • First Look

New Research and Ideas, October 23, 2018

allow testing for and predicting firm-specific coefficients, thereby distinguishing between effects that have a significant mean versus significant variance. RCMs may also be used to explore the sources of firm heterogeneous effects. We... View Details
Keywords: Dina Gerdeman

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