Publications

2014
Working Paper

Non-Adherence in Health Care: A Positive and Normative Analysis

By: Mark Egan and Tomas J. Philipson

Non-adherence in health care results when a patient does not initiate or continue care that a provider has recommended. Previous research identifies non-adherence as a major source of waste in US health care, totaling approximately 2.3% of GDP, and have proposed a... View Details

Keywords: Health Care and Treatment; Behavior; Economics; Analysis; Mathematical Methods

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20 Nov 2018
First Look

New Research and Ideas, November 20, 2018

consequentially experienced higher asset growth and increased market share during the crisis. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=54253 November 8, 2018 NEJM Catalyst Transitioning Payment Models: Fee-for-Service to Value-Based View Details

Keywords: Dina Gerdeman

27 Sep 2011
First Look

First Look: September 27

Industry Author:Arthur Daemmrich Abstract Fiercely contested before, during, and since its passage, the 2010 Patient Protection and Affordable Care Act (ACA) will restructure the U.S. healthcare market if fully implemented in coming... View Details

Keywords: Sean Silverthorne

December 1998 (Revised September 1999)
Case

Novartis: Betting on Life Sciences

By: Ray A. Goldberg, Carin-Isabel Knoop and Srinivas Sunder

The merger of Ciba-Geigy and Sandoz produced genomic-based synergies for health care, agribusiness, and nutritional supplements. How to build on the strength of the individual divisions and provide synergies that would continue Novartis' leadership role is the question... View Details

Keywords: Mergers and Acquisitions; Business Divisions; Health Care and Treatment; Leadership; Product Positioning; Science-Based Business; Corporate Strategy; Pharmaceutical Industry

30 Aug 2011
First Look

First Look: August 30

in Oral Care Rebecca M. Henderson and Ryan JohnsonHarvard Business School Case 311-120 In 2011, Colgate-Palmolive (Colgate) was the global leader in oral care, with a dominant market share lead in toothpaste and a growing presence in... View Details

Keywords: Sean Silverthorne

24 Jan 2017
First Look

First Look at New Research: January 24, 2017

Yoshimi Anzai, Marta E. Heilbrun, Derek Haas, Luca Boi, Kirk Moshre, Satoshi Minoshima, and Vivian S. Lee Abstract—The lack of understanding the true costs (not charges) of delivering health care services poses tremendous challenges in... View Details

Keywords: Sean Silverthorne

October 2005 (Revised September 2006)
Case

DentalCorp

By: Richard G. Hamermesh and Ricardo Reisen de Pinho

DentalCorp is the fifth largest provider of dental insurance in Brazil and has tripled its sales in the past two years. Whether to expand to Chile or to continue expansion in Brazil is the major strategic choice facing the company at the end of 2004. View Details

Keywords: International Finance; Expansion; Entrepreneurship; Health Care and Treatment; Global Strategy; Insurance Industry; Health Industry; Brazil; Chile

September 2021
Article

Kidney Exchange: An Operations Perspective

By: Itai Ashlagi and Alvin E. Roth

Many patients in need of a kidney transplant have a willing but incompatible (or poorly matched) living donor. Kidney exchange programs arrange exchanges among such patient-donor pairs, in cycles and chains of exchange, so each patient receives a compatible kidney.... View Details

Keywords: Kidney Exchange Programs; Matching; Health Disorders; Health Care and Treatment; Programs; Design

September 2012
Supplement

Intraoperative Radiotherapy for Breast Cancer (B)

By: Willy Shih

The intraoperative radiotherapy (IORT) business at Carl Zeiss Meditec had struggled with growth since the time of the (A) case. Though the unit had grown revenues in excess of 50% and had exceeded its EBIT target, it faced several key strategic choices. Should it... View Details

Keywords: Radiotherapy; Breast Cancer; Brachytherapy; Therapeutic Radiation; Oncology; Oncology Treatment Systems; Elekta AB; Varian Medical Systems; Xoft; Electronic Brachytherapy; Intraoperative Radiotherapy; Disruptive Innovation; Health Care and Treatment; Entrepreneurship; Technological Innovation; Growth and Development Strategy; Health Industry; Germany

15 Oct 2007
Research & Ideas

Businesses Beware: The World Is Not Flat

expansion," Ghemawat argues. While identifying similarities from one place to the next is essential, effective cross-border strategies will take careful stock of differences as well. An expert on global strategy, Ghemawat lays out an... View Details

Keywords: by Martha Lagace

22 Aug 2005
Research & Ideas

Balancing the Future Against Today’s Needs

It is a classic leadership challenge of the early twenty-first century: How do you steer your business and motivate your people to pursue breakthrough growth while giving proper attention to executing the here and now with the utmost care... View Details

Keywords: by Paul Michelman

2022
Book

Democratize Work: The Case for Reorganizing the Economy

By: Isabelle Ferreras, Julie Battilana and Dominique Méda

What happens to a society—and a planet—when capitalism outgrows democracy? The tensions between democracy and capitalism are longstanding, and they have been laid bare by the social effects of COVID-19. The narrative of “essential workers” has provided thin cover for... View Details

Keywords: Democratic Capitalism; Essential Workers; Sustainability; Equality and Inequality; Climate Change; Social Issues

2021
Working Paper

Kidney Exchange: An Operations Perspective

By: Itai Ashlagi and Alvin E. Roth

Many patients in need of a kidney transplant have a willing but incompatible (or poorly matched) living donor. Kidney exchange programs arrange exchanges among such patient-donor pairs, in cycles and chains of exchange, so each patient receives a compatible kidney.... View Details

Keywords: Kidney Exchange Programs; Health Disorders; Health Care and Treatment; Programs; Design

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September 2018 (Revised December 2019)
Case

Zebra Medical Vision

By: Shane Greenstein and Sarah Gulick

An Israeli startup founded in 2014, Zebra Medical Vision developed algorithms that produced diagnoses from X-rays, mammograms, and CT-scans. The algorithms used deep learning and digitized radiology scans to create software that could assist doctors in making... View Details

January 2005 (Revised March 2006)
Case

Molecular Insight Pharmaceuticals, Inc.

By: Richard G. Hamermesh and Edwin W. Parkinson III

Molecular Insight has developed a novel biopharmaceutical to detect heart attacks. The company's unique approach to intellectual property protection uses the Hatch Waxman Act and the Orphan Drug Act. The company is struggling to raise $7 million in Series B financing.... View Details

Keywords: Intellectual Property; Health Care and Treatment; Pharmaceutical Industry; Health Industry

August 2016
Article

Value-Based Breast Cancer Care: A Multidisciplinary Approach for Defining Patient-Centered Outcomes

By: Fayanju M. Oluwadamilola, Tinisha L. Mayo, Tracy E. Spinks, Seohyun Lee, Carlos H. Barcenas, Benjamin D. Smith, Sharon H. Giordano, Rosa F. Hwang, Richard A. Ehlers, Jesse C. Selber, Ronald Walters, Debu Tripathy, Kelly K. Hunt, Thomas A. Buchholz, Thomas W. Feeley and Henry M. Kuerer

Purpose. Value in healthcare—i.e., patient-centered outcomes achieved per healthcare dollar spent—can define quality and unify performance improvement goals with health outcomes of importance to patients across the entire cycle of care. We describe the process... View Details

Keywords: Health Disorders; Value; Health Care and Treatment; Performance Improvement; Health Industry

June 2023
Case

Verve Therapeutics: Taking DNA Editing to Heart

By: Shikhar Ghosh and Shweta Bagai

Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details

Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry

January 2023
Case

Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery

By: Regina Herzlinger and Brian Walker

What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details

Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry

March 2014 (Revised February 2015)
Case

Loki Capital Management

By: Joseph B. Fuller, Shikhar Ghosh and Matthew Preble

In December 2013, Michael Kane was preparing to launch his start-up's first hedge fund. While pleased with the development of the business, he wanted to address a few lingering issues before going any further. He debated whether or not to fire the company's chief... View Details

Keywords: Hedge Fund; Hedge Funds; Equity Split; Fundraising; Investor Clientele; Team Building; Human Resource Management; Human Capital; Human Resources; Equity; Financial Services Industry; United States