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  • All HBS Web  (4,700)
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  • 2018
  • Chapter

The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century

By: Nicholas Bagley, Benjamin Berger, Amitabh Chandra, Craig Garthwaite and Ariel Dora Stern
On the 35th anniversary of the adoption of the Orphan Drug Act (ODA), we describe the enormous changes in the markets for therapies for rare diseases that have emerged over recent decades. The most prominent example is the fact that the profit-maximizing price of new... View Details
Keywords: Health Care and Treatment; Laws and Statutes; Research and Development; Investment; Markets; Monopoly
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Bagley, Nicholas, Benjamin Berger, Amitabh Chandra, Craig Garthwaite, and Ariel Dora Stern. "The Orphan Drug Act at 35: Observations and an Outlook for the Twenty-First Century." Chap. 4 in Innovation Policy and the Economy, Volume 19, edited by Josh Lerner and Scott Stern, 97–137. University of Chicago Press, 2018.
  • 2017
  • Working Paper

Identifying Sources of Inefficiency in Health Care

By: Amitabh Chandra and Douglas O. Staiger
In medicine, the reasons for variation in treatment rates across hospitals serving similar patients are not well understood. Some interpret this variation as unwarranted and push standardization of care as a way of reducing allocative inefficiency. However, an... View Details
Keywords: Health Care and Treatment; Performance Efficiency; Performance Productivity; Mathematical Methods
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Chandra, Amitabh, and Douglas O. Staiger. "Identifying Sources of Inefficiency in Health Care." NBER Working Paper Series, No. 24035, November 2017.
  • 2017
  • Chapter

Multinational Activity in Emerging Markets: How and When Does Foreign Direct Investment Promote Growth?

By: Laura Alfaro
Among the prominent economic trends in recent decades is the exponential increase in flows of goods and capital driven by technological progress and a falling number of restrictions. A key driver of this phenomenon has been the cross-border production, foreign... View Details
Keywords: Multinational Activity; Growth; Spillovers; Complementarities; Foreign Direct Investment; Emerging Markets; Growth and Development; Multinational Firms and Management
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Alfaro, Laura. "Multinational Activity in Emerging Markets: How and When Does Foreign Direct Investment Promote Growth?" In Geography, Location, and Strategy. Vol. 36, edited by Juan Alcácer, Bruce Kogut, Catherine Thomas, and Bernard Yin Yeung, 429–462. Advances in Strategic Management. Emerald Publishing Limited, 2017.
  • 13 Jan 2003
  • Research & Ideas

Making Biotech Work as a Business

technologies for drug discovery.) And patients with previously unmet medical needs can now get treatments that were not available before. That should be inspiring, he reminded the audience. Economic frustrations remain, however. Pisano... View Details
Keywords: by Martha Lagace; Biotechnology; Health; Technology
  • Research Summary

Platform Competition

Technology has challenged the underlying foundations of business, and firms must evaluate and change strategies accordingly. Professor Halaburda studies the interaction of technology and economic theory, and her findings indicate that conventional wisdom and rules... View Details

  • 18 Sep 2007
  • First Look

First Look: September 18, 2007

activity to distance themselves from competitors. Microfinance: Business, Profitability, and the Creation of Social Value Author:Michael Chu Publication:Chap. 28 in Business Solutions for the Global Poor: Creating Social and Economic... View Details
Keywords: Martha Lagace
  • 24 Jan 2012
  • First Look

First Look: Jan. 24

http://www.people.hbs.edu/mtripsas/articles/Benner%20Tripsas%20SMJ%20forthcoming.pdf Evidence from the Firm: A New Approach to Understanding Corruption Authors:Shawn A. Cole and Anh Tran Publication:In International Handbook on the View Details
Keywords: Sean Silverthorne

    Sandlands Vineyards

    Approximately 80% of the 9,000 wineries in the US breakeven or lose money. An even greater percentage, perhaps 90-95%, lose money on an economic basis (i.e., after a charge for the capital employed).  Tegan Passalacqua is a Californian winemaker who appears to have... View Details

    • 20 Mar 2000
    • Research & Ideas

    Incubators: The New Venture Capitalists?

    kicking off a panel discussion at Cyberposium 2000. "But I think it's fair to characterize the incubator space as rather a sleepy one." Until now, that is. Once largely the domain of universities and public economic View Details
    Keywords: by Kenneth Liss
    • August 2023 (Revised October 2023)
    • Case

    Beyond the Barricades: Chile 2023

    By: Debora Spar, Willis Emmons, Leonard A. Schlesinger and Ruth Costas
    Chile, often considered among Latin America's greatest economic success stories, suffered a shocking wave of protests in October 2019, as its citizens demanded reforms across healthcare and education systems, and protested inequality and rising costs of living. As... View Details
    Keywords: Government Administration; Developing Countries and Economies; Economic Growth; Social Issues; Wealth and Poverty; Public Opinion; Equality and Inequality; Public Administration Industry; Chile; Latin America; South America
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    Spar, Debora, Willis Emmons, Leonard A. Schlesinger, and Ruth Costas. "Beyond the Barricades: Chile 2023." Harvard Business School Case 324-005, August 2023. (Revised October 2023.)
    • Career Coach

    Yiwei Zhao

    Yiwei enjoys helping students explore opportunities in the following industries: Technology (big tech and growth-stage tech), self-driving cars, AI/ML, and consulting; and functions: product operations, product management, program management, chief of staff, View Details
    • 25 Feb 2002
    • Research & Ideas

    The Country Effect: Does Location Matter?

    market driven structure. The blending of national cultures over time in Hong Kong, where a high level of economic success has been recorded, may ultimately hurt the performance of companies in that country. H.K. firms have not View Details
    Keywords: by Sean Silverthorne
    • January 2007 (Revised October 2011)
    • Case

    Roppongi Hills: City Within a City

    By: Anita Elberse, Andrei Hagiu and Masako Egawa
    Minoru Mori is the CEO of Mori Building, which has built Roppongi Hills, an ambitious large-scale, mixed-use development in Tokyo, Japan that includes high-end retail, restaurants, hotel, office, library, and art museum. A destination site for tourists and local... View Details
    Keywords: Buildings and Facilities; Development Economics; Brands and Branding; Urban Development; Competition; Real Estate Industry; Tokyo
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    Elberse, Anita, Andrei Hagiu, and Masako Egawa. "Roppongi Hills: City Within a City." Harvard Business School Case 707-431, January 2007. (Revised October 2011.)
    • Article

    Platform Competition: Betfair and the U.K. Market for Sports Betting

    By: Ramon Casadesus-Masanell and Neil Campbell
    We examine two episodes of strategic interaction in the U.K. betting industry: (i) Betfair (an entrant multi-sided platform or MSP) vs. Flutter (also an MSP) and (ii) Betfair vs. traditional bookmakers. We find that although Betfair was an underfunded second mover in... View Details
    Keywords: Platform Design; Betting; Complements; Competing Business Models; Co-opetition; Entry; Multi-Sided Platforms; Design; Network Effects; Business Model; Competition; Cooperation
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    Casadesus-Masanell, Ramon, and Neil Campbell. "Platform Competition: Betfair and the U.K. Market for Sports Betting." Special Issue on Platforms. Journal of Economics & Management Strategy 28, no. 1 (Spring 2019): 29–40.
    • 07 Dec 2017
    • HBS Seminar

    Eric von Hippel, MIT Sloan School of Management

    • March 2006 (Revised June 2010)
    • Case

    Eldeco: Playing in the Big League

    By: Arthur I Segel, Nicolas P. Retsinas and Siddarth Yog
    In 2001, Pankaj Bajaj is considering whether to go forward with a residential development outside New Delhi. Facing an uncooperative local authority, he must determine how to evaluate the risks of proceeding against the potential loss of a golden opportunity to bring... View Details
    Keywords: Developing Countries and Economies; Construction; Government and Politics; Risk Management; Emerging Markets; Business and Government Relations; Conflict and Resolution; Real Estate Industry; New Delhi
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    Segel, Arthur I., Nicolas P. Retsinas, and Siddarth Yog. "Eldeco: Playing in the Big League." Harvard Business School Case 206-116, March 2006. (Revised June 2010.)
    • February 1998 (Revised October 2002)
    • Case

    Uganda and the Washington Consensus

    By: Huw Pill and Courtenay Sprague
    Under the direction of President Museveni, much of the world has heaped praise on Uganda for transforming its economy from devastation to growth and managing the ethnic and racial strife that has divided the country in the past. Following a decade of reforms, Uganda is... View Details
    Keywords: Macroeconomics; Economy; Policy; Analysis; Development Economics; Borrowing and Debt; Management; Developing Countries and Economies; Uganda
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    Pill, Huw, and Courtenay Sprague. "Uganda and the Washington Consensus." Harvard Business School Case 798-047, February 1998. (Revised October 2002.)
    • 2008
    • Book

    Mexico Since 1980

    By: Stephen Haber, Herb Klein, Noel Maurer and Kevin Middlebrook
    This book addresses two questions that are crucial to understanding Mexico's current economic and political challenges. Why did the opening up of the economy to foreign trade and investment not result in sustained economic growth? Why has electoral democracy not... View Details
    Keywords: Developing Countries and Economies; Foreign Direct Investment; Government and Politics; Growth and Development; Law Enforcement; Welfare or Wellbeing; Mexico
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    Haber, Stephen, Herb Klein, Noel Maurer, and Kevin Middlebrook. Mexico Since 1980. World Since 1980. Cambridge University Press, 2008.
    • June 2010 (Revised August 2013)
    • Case

    Remaking Singapore

    By: Michael E. Porter, Boon Siong Neo and Christian H.M. Ketels
    Looking through the lenses of both macro and micro economic policy, this case examines how Singapore has achieved such stellar success throughout its history, from independence through 2008. The case discusses the different policy choices the Singaporean government has... View Details
    Keywords: History; Development Economics; Industry Clusters; Competitive Advantage; Policy; Economic Growth; Microeconomics; Government and Politics; Macroeconomics; Singapore
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    Porter, Michael E., Boon Siong Neo, and Christian H.M. Ketels. "Remaking Singapore." Harvard Business School Case 710-483, June 2010. (Revised August 2013.)
    • Program

    Behavioral Economics—Virtual

    Summary What if you could predict how customers will respond to a product? Or how employees will decide to implement a new initiative? In Behavioral Economics—Virtual, you'll acquire a dynamic framework for interpreting, analyzing, and leveraging behavioral View Details
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