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  • All HBS Web  (5,816)
    • People  (4)
    • News  (1,259)
    • Research  (3,440)
    • Events  (83)
    • Multimedia  (192)
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  • Article

Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions

By: Andrea Blasco, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian and Karim R. Lakhani
Open data science and algorithm development competitions offer a unique avenue for rapid discovery of better computational strategies. We highlight three examples in computational biology and bioinformatics research where the use of competitions has yielded significant... View Details
Keywords: Computational Biology; Bioinformatics; Innovation Competitions; Research; Collaborative Innovation and Invention
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Blasco, Andrea, Michael G. Endres, Rinat A. Sergeev, Anup Jonchhe, Max Macaluso, Rajiv Narayan, Ted Natoli, Jin H. Paik, Bryan Briney, Chunlei Wu, Andrew I. Su, Aravind Subramanian, and Karim R. Lakhani. "Advancing Computational Biology and Bioinformatics Research Through Open Innovation Competitions." PLoS ONE 14, no. 9 (September 2019).
  • August 2018
  • Case

Christine Lagarde (A): A French Prime Minister Calls

By: Julie Battilana and Carin-Isabel Knoop
This case covers formative events and influences in Christine Lagarde’s childhood and her trajectory from studying political science and law to heading the world’s largest law firm. As she prepares to transition back to practice in 2005, the new Prime Minister of... View Details
Keywords: Personal Development and Career; Power and Influence; Decision Making
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Battilana, Julie, and Carin-Isabel Knoop. "Christine Lagarde (A): A French Prime Minister Calls." Harvard Business School Case 419-017, August 2018.
  • May 2014 (Revised November 2014)
  • Supplement

Houston We Have A Solution: NASA and Open Innovation (B)

By: Michael Tushman, Hila Lifshitz-Assaf and Kerry Herman
Jeff Davis, director of Space Life Sciences Directorate at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on... View Details
Keywords: Technology; Aerospace Industry
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Tushman, Michael, Hila Lifshitz-Assaf, and Kerry Herman. "Houston We Have A Solution: NASA and Open Innovation (B)." Harvard Business School Supplement 414-057, May 2014. (Revised November 2014.)
  • December 2010 (Revised March 2015)
  • Case

The Wright Brothers and Their Flying Machines

By: Tom Nicholas and David Chen
Wilbur (1867-1912) and Orville (1871-1948) Wright were fascinated by the mystery of flight and they built on the ideas of prominent earlier figures such as Octave Chanute (1832-1910) the French-born American who was influential in fostering the free exchange of ideas... View Details
Keywords: Entrepreneurship; Business History; Technological Innovation; Patents; Knowledge Sharing; Air Transportation; Air Transportation Industry; Europe; United States
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Nicholas, Tom, and David Chen. "The Wright Brothers and Their Flying Machines." Harvard Business School Case 811-034, December 2010. (Revised March 2015.)
  • 19 Jun 2019
  • News

Faculty Books in Brief: Summer 2019

    The Peacemaker's Code

    - WINNER OF THE "NATIONAL INDIE EXCELLENCE AWARD" FOR BEST SCIENCE FICTION (2021).
    - Currently in development as a TV Series.

    The book's many themes—war & peace, history, strategy, negotiation, leadership,... View Details

      Connect, Then Lead (by Amy Cuddy, John Neffinger, & Matt Kohut)

      Is it better to be loved or feared?

       Niccolò Machiavelli pondered that timeless conundrum 500 years ago and hedged his bets. “It may be answered that one should wish to be both,” he acknowledged, “but because it is difficult to unite them in one person, it... View Details

      • 07 Feb 2007
      • Working Paper Summaries

      The Value of Openness in Scientific Problem Solving

      Keywords: by Karim R. Lakhani, Lars Bo Jeppesen, Peter A. Lohse & Jill A. Panetta
      • 08 Sep 2010
      • News

      Emerging Scholar Award

      • 14 Nov 2019
      • HBS Seminar

      Volodymyr Babich, Georgetown University

        Nailing Prediction: Experimental Evidence on the Value of Tools in Predictive Model Development

        Predictive model development is understudied despite its importance to modern businesses. Although prior discussions highlight advances in methods (along the dimensions of data, computing power, and algorithms) as the primary driver of model quality, the value of... View Details
        • Web

        Technology & Operations Management - Faculty & Research

        repeated decisions. 2025 Working Paper Where Discovery Happens: Research Institutions and Fundamental Knowledge in the Life-Sciences By: Amitabh Chandra and Connie Xu Fundamental knowledge in the life sciences has consequential... View Details
        • January 2016
        • Case

        Open Innovation at Fujitsu (A)

        By: Amy C. Edmondson and Jean-François Harvey
        This case study examines the open innovation journey at Fujitsu, a global information and communication technology company. The case ends with the location decision between Tokyo, Japan, downtown San Francisco or Sunnyvale, California, regarding establishing a small... View Details
        Keywords: Open Innovation; Collaboration; Culture Change; Leadership; Japan; United States; Inter-organizational Relationships; Teaming; Maker Movement; Nascent Industries; Change Management; Leading Change; Organizational Culture; Emerging Markets; Collaborative Innovation and Invention; Information Technology Industry; Technology Industry; Sunnyvale; Tokyo; San Francisco
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        Edmondson, Amy C., and Jean-François Harvey. "Open Innovation at Fujitsu (A)." Harvard Business School Case 616-034, January 2016.
        • April 2024 (Revised October 2024)
        • Case

        New Belgium Brewing and Climate Change

        By: Michael W. Toffel, Kenneth P. Pucker and Michael Norris
        In 2023, Colorado-based craft brewery New Belgium Brewing was considering how best to meet its emissions reduction targets. After decades of growth, the beermaker had grown to become one of the largest craft brewers in the U.S., and was purchased in 2019 by Japanese... View Details
        Keywords: Beer; Carbon Accounting; Carbon Credits; Operation Management; Renewable Energy; Supply Chain; Environmental Sustainability; Climate Change; Corporate Social Responsibility and Impact; Environmental Accounting; Food and Beverage Industry; United States; Colorado
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        Toffel, Michael W., Kenneth P. Pucker, and Michael Norris. "New Belgium Brewing and Climate Change." Harvard Business School Case 624-069, April 2024. (Revised October 2024.)

          W. Carl Kester

          Carl Kester is a Baker Foundation Professor and the George Fisher Baker Jr. Professor of Business Administration, Emeritus at Harvard Business School. He is a member of the Finance Unit. He served as Deputy Dean for Academic Affairs (2006-2010), Chairman of the... View Details

          Keywords: asset management; banking; education industry; financial services; investment banking industry; pharmaceuticals; private equity (LBO funds)
          • 26 Jul 2023
          • News

          STEM Needs More Women. Recruiters Often Keep Them Out

          • 2003
          • Report

          UK Competitiveness: Moving to the Next Stage

          By: Michael E. Porter and Christian H.M. Ketels

          In October 2002, the Economic and Social Research Council (ESRC) appointed Professor Michael Porter and his team to conduct a brief, three-month review of the existing evidence on UK competitiveness. The effort was funded jointly by the ESRC and the Department of... View Details

          Keywords: Competition; Economics; Performance Productivity; Management Analysis, Tools, and Techniques; Research and Development; Competency and Skills; Investment; Assets; Corporate Strategy; Policy; Management; Knowledge Use and Leverage; United Kingdom; United States
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          Porter, Michael E., and Christian H.M. Ketels. "UK Competitiveness: Moving to the Next Stage." DTI Economics Paper, May 2003.
          • 25 Aug 2021
          • News

          PRIMO 2021: An Introduction to Research

          • 23 Oct 2020
          • Video

          Entrepreneurship Opportunities in a Post-COVID World: The Future of Work

          • October 2019 (Revised February 2025)
          • Case

          A Conversation with Ellen J. Kullman, Chairman & CEO of DuPont, 2009-2015

          By: Lynn S. Paine and Will Hurwitz
          Ellen J. Kullman, the retired Chairman and CEO of DuPont, describes how she guided the storied science and technology company through a contentious proxy battle with activist investor Trian Partners, which acquired DuPont shares in 2013 and sought to break up the... View Details
          Keywords: Agribusiness; Capital Structure; Corporate Accountability; Corporate Governance; Institutional Investing; Leadership; Leadership Style; Management; Transformation; Agriculture and Agribusiness Industry; Chemical Industry; United States
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          Paine, Lynn S., and Will Hurwitz. "A Conversation with Ellen J. Kullman, Chair & CEO of DuPont, 2009-2015." Harvard Business School Case 320-017, October 2019. (Revised February 2025.)
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