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- December 2023 (Revised March 2024)
- Case
Manufacturing Moderna's Future
By: Satish Tadikonda and William Marks
In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details
- 2023
- Working Paper
Money, Time, and Grant Design
By: Kyle Myers and Wei Yang Tham
The design of research grants has been hypothesized to be a useful tool for
influencing researchers and their science. We test this by conducting two thought
experiments in a nationally representative survey of academic researchers. First,
we offer participants a... View Details
- 2023
- Working Paper
Debiasing Treatment Effect Estimation for Privacy-Protected Data: A Model Auditing and Calibration Approach
By: Ta-Wei Huang and Eva Ascarza
Data-driven targeted interventions have become a powerful tool for organizations to optimize business outcomes
by utilizing individual-level data from experiments. A key element of this process is the estimation
of Conditional Average Treatment Effects (CATE), which... View Details
- December 2023
- Case
Raízen: Helping to Decarbonize the World?
By: Gunnar Trumbull, Pedro Levindo, Daniel Tong and Rafaella Mazza
Raízen, the world’s largest sugar and ethanol producer, strived to find ways to expand the second-generation ethanol (E2G) market, which it pioneered. The company planned to invest R$24 billion (around $4.6 billion) in 20 production plants, with a total capacity to... View Details
- December 2023 (Revised July 2024)
- Case
Boortmalt: The Master Maltster
By: Forest Reinhardt, Jose B Alvarez, Damien McLoughlin, Lena Duchene and Emer Moloney
By May 2023, Boortmalt was the world’s leading producer of malt, with a production capacity of 3 million tonnes, 15% of global market share, and 27 malting plants across five continents. It had recently acquired a major competitor and had sustained an EBITDA growth of... View Details
Keywords: Plant-Based Agribusiness; Mergers and Acquisitions; Talent and Talent Management; Customer Focus and Relationships; Values and Beliefs; Financing and Loans; Employee Relationship Management; Collaborative Innovation and Invention; Innovation Leadership; Knowledge Sharing; Leadership Style; Business or Company Management; Growth and Development Strategy; Growth Management; Management Style; Resource Allocation; Corporate Social Responsibility and Impact; Strategic Planning; Environmental Sustainability; Organizational Culture; Agriculture and Agribusiness Industry; Belgium; Europe
- December 2023
- Case
Santa Elena: Table Grape Production in Chile's Water-Challenged Regions
By: Forest Reinhardt, Jenyfeer Martinez Buitrago and Mariana Cal
In the fiscal year ending in September 2022, Santa Elena, Chile’s fifth-ranking table grape exporter, a grape producer and exporter since 1980, had exported around 3.5 million boxes (18-pound each). But, due to a 13-year-long drought that plagued table grape-growing... View Details
Keywords: Plant-Based Agribusiness; Climate Change; Environmental Regulation; Environmental Sustainability; Natural Resources; Food; Environmental Law; Problems and Challenges; Weather; Adaptation; Business Strategy; Organizational Change and Adaptation; Agriculture and Agribusiness Industry; Chile; South America; Latin America
- 2023
- Article
Benchmarking Large Language Models on CMExam—A Comprehensive Chinese Medical Exam Dataset
By: Junling Liu, Peilin Zhou, Yining Hua, Dading Chong, Zhongyu Tian, Andrew Liu, Helin Wang, Chenyu You, Zhenhua Guo, Lei Zhu and Michael Lingzhi Li
Recent advancements in large language models (LLMs) have transformed the field of question answering (QA). However, evaluating LLMs in the medical field is challenging due to the lack of standardized and comprehensive datasets. To address this gap, we introduce CMExam,... View Details
- 2023
- Other Article
The Harvard USPTO Patent Dataset: A Large-Scale, Well-Structured, and Multi-Purpose Corpus of Patent Applications
By: Mirac Suzgun, Luke Melas-Kyriazi, Suproteem K. Sarkar, Scott Duke Kominers and Stuart Shieber
Innovation is a major driver of economic and social development, and information about many kinds of innovation is embedded in semi-structured data from patents and patent applications. Though the impact and novelty of innovations expressed in patent data are difficult... View Details
- November 2023
- Case
Gabon Special Economic Zone
By: John Macomber and Wale Lawal
Tropical rain forest covers about 80% of the West African nation of Gabon, part of the Congo Basin and the "lungs of the world." Gabon is one of the first nations to earn revenue from carbon sequestration...as long as the rain forest remains intact. There are... View Details
- November 2023 (Revised April 2024)
- Case
BiomX: Bringing Phage Back to the Stage
By: Paul A. Gompers, Elie Ofek, Orna Dan and Emilie Billaud
In the spring of 2023, and following the favorable results of a trial involving its phage cocktail for treating lung infections among cystic fibrosis (CF) patients, the leadership of BiomX had several critical issues to wrestle with. First, given its precarious... View Details
- November 2023 (Revised November 2023)
- Case
Decarbonizing Shipping at A.P. Møller-Maersk (A)
By: Willy Shih, Michael W. Toffel and Kelsey Carter
Container shipping was responsible for moving more than 80% of globally traded goods, and almost 3% of global greenhouse gas emissions. A.P. Møller-Maersk, one of the top three container lines, conducted an extensive lifecycle assessment (LCA) of alternative fuels,... View Details
- November 2023 (Revised August 2024)
- Background Note
Life Cycle Assessment: An Overview
By: Willy C. Shih, Michael W. Toffel and Kelsey Carter
Life cycle assessment (LCA) is a holistic approach to quantifying the environmental impacts—including resources consumed and wastes produced—associated with the entire life cycle of a product, from the production or extraction of the raw materials used in its creation,... View Details
- November 2023 (Revised March 2024)
- Case
Infarm: Betting the (Indoor) Farm on Food Security
By: Elie Ofek
In the summer of 2023, the co-founders of Infarm, a controlled environment agriculture (CEA) company, were contemplating a major pivot going forward. While Infarm had successfully shown it could grow over 75 products—mainly herbs, leafy greens and mushrooms—in modular... View Details
- November 2023 (Revised July 2024)
- Background Note
Corporate Climate Targets
By: Willy C. Shih, Michael W. Toffel and Kelsey Carter
Companies that are addressing climate change by mitigating their greenhouse gas emissions often set reduction targets. This note describes several types of widely used carbon reduction targets, including carbon neutral, science based, net zero, real zero, and carbon... View Details
- November 2023 (Revised April 2024)
- Case
Khanmigo: Revolutionizing Learning with GenAI
By: William A. Sahlman, Allison M. Ciechanover and Emily Grandjean
Already a leader in the edtech space since its 2008 launch, Khan Academy was now one of the first edtech organizations to embrace generative artificial intelligence ("genAI"). In March 2023, Khan Academy began beta testing Khanmigo, a genAI “guide” and tutor built with... View Details
- November–December 2023
- Article
Look the Part? The Role of Profile Pictures in Online Labor Markets
By: Isamar Troncoso and Lan Luo
Profile pictures are a key component of many freelancing platforms, a design choice that can impact hiring and matching outcomes. In this paper, we examine how appearance-based perceptions of a freelancer’s fit for the job (i.e., whether a freelancer "looks the part"... View Details
- October 2023 (Revised April 2024)
- Case
Veeva Systems: The Next Frontier
By: Satish Tadikonda and William Marks
Born out of a desire to bring technological advances in enterprise software into the healthcare vertical, Peter Gassner and Matt Wallach founded Veeva to bring life sciences companies into the digital age for data management in both the commercial and R&D sectors. Over... View Details
- October 2023 (Revised March 2024)
- Case
KOKO Networks: Bridging Energy Transition and Affordability with Carbon Financing
By: George Serafeim, Siko Sikochi and Namrata Arora
The problem was massive: two million hectares of African forests were lost annually to charcoal production for cooking, an area equivalent to 13 times Greater London, resulting in one billion tons of carbon emissions yearly. At the same time, an estimated 700,000... View Details
Keywords: Clean Tech; Digital; Carbon Credits; Carbon Offsetting; Climate Change; Entrepreneurship; Energy Sources; Environmental Sustainability; Health; Market Design; Business Startups; Transition; Environmental Regulation; Policy; Energy Industry; Consumer Products Industry; Africa; Kenya; Rwanda
- 2023
- Working Paper
The Buy-In Effect: When Increasing Initial Effort Motivates Behavioral Follow-Through
By: Holly Dykstra, Shibeal O'Flaherty and A.V. Whillans
Behavioral interventions often focus on reducing friction to encourage behavior change. In
contrast, we provide evidence that adding friction can promote long-term behavior change when
behaviors involve repeated costly efforts over longer time horizons. In... View Details