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  • 25 Mar 2019
  • Research & Ideas

The Secret Life of Supply Chains

Like archaeologists digging on a remote hillside, business researchers have unearthed an important segment of the United States economy all but hidden from traditional innovation policy, yet accounting for tens of millions of jobs crucial... View Details
Keywords: by Michael Blanding; Manufacturing; Service
  • February 2008 (Revised August 2008)
  • Case

EXACT Sciences Corp.: Commercializing a Diagnostic Test

By: Regina E. Herzlinger
This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details
Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry
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Herzlinger, Regina E. "EXACT Sciences Corp.: Commercializing a Diagnostic Test." Harvard Business School Case 308-090, February 2008. (Revised August 2008.)
  • 2001
  • Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn
U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details
Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry
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Henderson, Rebecca, and Ian Cockburn. "Publicly Funded Science and the Productivity of the Pharmaceutical Industry." In Innovation Policy and the Economy, Volume 1, edited by Adam B. Jaffe, Josh Lerner, and Scott Stern, 1–34. MIT Press, 2001.
  • 2023
  • Book

Right Kind of Wrong: The Science of Failing Well

By: Amy Edmondson
A revolutionary guide that will transform your relationship with failure, from the pioneering researcher of psychological safety and award-winning Harvard Business School professor Amy Edmondson.

We used to think of failure as the opposite of success. Now,... View Details
Keywords: Failure; Success
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Edmondson, Amy. Right Kind of Wrong: The Science of Failing Well. New York, NY: Atria Books, 2023.
  • 2005
  • Book

Fit In Stand Out: Mastering the FISO Factor, The Key to Leadership Effectiveness in Business and Life

By: Blythe J. McGarvie
While studying and practicing business effectiveness, leadership expert Blythe McGarvie uncovered a vital lesson: successful leaders are systems thinkers. Two forces power business systems: integration (Fit In) and transformation (Stand Out). By mastering the FISO... View Details
Keywords: Integration; Leadership; Transformation
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McGarvie, Blythe J. Fit In Stand Out: Mastering the FISO Factor, The Key to Leadership Effectiveness in Business and Life. McGraw-Hill, 2005.
  • March 2022
  • Case

Shanghai Pudong Science and Technology Investment Co., Ltd.: December 2014

By: Josh Lerner, Luyang Zhang, Xinlai Tong and Yue Kong
In early December 2014, the senior team of Pudong Science and Technology Investment (hereafter, Pudong S&T) gathered in the offices of their chairman, Dr. Xudong Zhu. Before completing its cross-border acquisition of Montage Technology, Pudong S&T—wholly owned by the... View Details
Keywords: Mergers and Acquisitions; Ownership Stake; Risk Management; Ownership Type; China
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Lerner, Josh, Luyang Zhang, Xinlai Tong, and Yue Kong. "Shanghai Pudong Science and Technology Investment Co., Ltd.: December 2014 ." Harvard Business School Case 822-111, March 2022.
  • Research Summary

International Competitiveness in High Technology and Science Based Sectors

By: Gary P. Pisano

This research project examines shifts in competitive capabilities of companies and countries in high technology and science based businesses.  It is particularly concerned with the potential loss of such capabilities in various industrial sectors in the... View Details

  • 04 Feb 2002
  • Research & Ideas

How a Juicy Brand Came Back to Life

Rush Limbaugh. Stern was an especially effective spokesperson. He got to know the founders of the business personally and conveyed to his listeners a genuine and infectious regard for the products and the people behind them. The brand's... View Details
Keywords: by John Deighton; Food & Beverage
  • May 2018 (Revised June 2018)
  • Case

Ashar Group: Brokers and Co-opetition in the Life Settlement Industry

By: Alexander Braun, Lauren H. Cohen, Christopher J. Malloy and Jiahua Xu
Connecting life insurance policyholders with potential investors (called Life Settlement Providers), Ashar Group plays a pivotal role in the industry. Its current position is, however, increasingly being challenged by consumer-direct models, led by major providers... View Details
Keywords: Insurance; Investment; Markets; Competitive Strategy; Cooperation; Financial Services Industry
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Braun, Alexander, Lauren H. Cohen, Christopher J. Malloy, and Jiahua Xu. "Ashar Group: Brokers and Co-opetition in the Life Settlement Industry." Harvard Business School Case 218-109, May 2018. (Revised June 2018.)
  • April 2024 (Revised November 2024)
  • Case

Moderna: Pioneering a People Platform to Accelerate Science Innovation

By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Biotechnology Industry; United States
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Sandino, Tatiana, Emil Dy, and Samuel Grad. "Moderna: Pioneering a People Platform to Accelerate Science Innovation." Harvard Business School Case 124-091, April 2024. (Revised November 2024.)
  • 19 Oct 2015
  • Research & Ideas

Business Research that Makes for Smarter Public Policy

to fill little gaps in the literature, and I continue to think that was excellent advice.” Just as researchers in the life sciences often target their work to tackle the most dangerous diseases, so argues... View Details
Keywords: by Michael Blanding
  • December 2020 (Revised February 2021)
  • Case

Kerry Group: Inspiring Food, Nourishing Life

By: Forest L. Reinhardt, José B. Alvarez, Damien McLoughlin, Tonia Labruyere and Tonia Junker
The Irish company Kerry Group, one of the leading global players in the taste and nutrition industry, wants to ensure its future growth in developing and developed markets. Founded in 1972 as a dairy cooperative, it had grown into a provider of taste and nutrition... View Details
Keywords: Agribusiness; Environmental Sustainability; Food; Nutrition; Growth and Development Strategy; Global Range; Market Entry and Exit; Customer Relationship Management; Agriculture and Agribusiness Industry
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Reinhardt, Forest L., José B. Alvarez, Damien McLoughlin, and Tonia Labruyere. "Kerry Group: Inspiring Food, Nourishing Life." Harvard Business School Case 721-019, December 2020. (Revised February 2021.)
  • August 2009
  • Case

Life Stories of Recent MBAs: Motivations

By: Nitin Nohria, Matthew D. Breitfelder and Daisy A Wademan Dowling
Keywords: Business Education; Motivation and Incentives
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Nohria, Nitin, Matthew D. Breitfelder, and Daisy A Wademan Dowling. "Life Stories of Recent MBAs: Motivations." Harvard Business School Case 410-031, August 2009.
  • February 2008 (Revised July 2008)
  • Case

Banco Compartamos: Life after the IPO

By: Michael Chu and Regina Garcia Cuellar
After an international IPO yielding extraordinary returns to original investors, Banco Compartamos, Mexico's leading microfinance institution, contemplates its future strategic and competing priorities: maintaining growth, defending industry, leadership, preserving... View Details
Keywords: Business Model; Microfinance; Initial Public Offering; Non-Governmental Organizations; Competition; Value Creation; Banking Industry; Mexico
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Chu, Michael, and Regina Garcia Cuellar. "Banco Compartamos: Life after the IPO." Harvard Business School Case 308-094, February 2008. (Revised July 2008.)
  • Article

What to Know About Locating in a Cluster

By: Willy C. Shih and Sen Chai
As a study of two industry clusters in Denmark shows, factors that can make clusters attractive—easy people movement and knowledge spillovers—can also make it harder for individual companies to retain proprietary knowledge. View Details
Keywords: Clusters; Clustering; Competitiveness; Life Sciences; Telecommunications; Science-based; Research And Development; Industry Clusters; Research; Innovation Strategy; Innovation and Management; Geographic Location; Pharmaceutical Industry; Biotechnology Industry; Telecommunications Industry; Food and Beverage Industry; Denmark
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Shih, Willy C., and Sen Chai. "What to Know About Locating in a Cluster." Art. 57117. MIT Sloan Management Review 57, no. 1 (Fall 2015): 104–107.
  • March 2011
  • Supplement

Padraig O'Ceidigh and Aer Arann: Building a Business in the Context of a Life - What Happened

By: Janet J. Kraus and Shirley Spence
Provides an epilogue to the problem posed in the companion case: what to do in the face of potential liquidation? View Details
Keywords: Natural Disasters; Crisis Management; Air Transportation; Entrepreneurship; Management Teams; Business or Company Management; Success; Decision Making; Air Transportation Industry; Republic of Ireland
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Kraus, Janet J., and Shirley Spence. "Padraig O'Ceidigh and Aer Arann: Building a Business in the Context of a Life - What Happened." Harvard Business School Supplement 811-090, March 2011.
  • October 2008
  • Supplement

John and Andrea Rice: Entrepreneurship and Life

By: Howard H. Stevenson and Shirley M. Spence
Video of an interview conducted by Professor Howard Stevenson with John and Andrea Rice. It presents their views on their notions of career success, finding happiness in life, managing their competitiveness, their goals for the next ten years, and the pursuit of... View Details
Keywords: Entrepreneurship; Success; Personal Development and Career; Opportunities; Happiness; Competitive Strategy
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Stevenson, Howard H., and Shirley M. Spence. "John and Andrea Rice: Entrepreneurship and Life." Harvard Business School Video Supplement 509-715, October 2008.
  • March 2017 (Revised February 2025)
  • Case

Edwin Land: The Art and Science of Innovation

By: Tom Nicholas, Christopher T. Stanton and Matthew G. Preble
Throughout the second half of the 20th century, Polaroid first invented—and then continuously reinvented—the field of instant photography. Under the leadership of its mercurial founder Edwin Land, the company regularly released new instant cameras and films, often... View Details
Keywords: Instant Photography; Company History; Change Management; Disruption; Forecasting and Prediction; Entrepreneurship; Business History; Innovation Strategy; Disruptive Innovation; Innovation and Management; Intellectual Property; Patents; Product Marketing; Brands and Branding; Product Launch; Product Development; Chemical Industry; Consumer Products Industry; United States
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Nicholas, Tom, Christopher T. Stanton, and Matthew G. Preble. "Edwin Land: The Art and Science of Innovation." Harvard Business School Case 817-107, March 2017. (Revised February 2025.)
  • May 9, 2024
  • Article

Business Education Is Broken: Here Are Strategies to Fix It

By: Andrew J. Hoffman
Business schools have lost their way. Students are schooled in a system that, having raised the standard of living for millions of people over centuries, is now facing systemic failures in both the environmental and social domains—failures that market forces cause and,... View Details
Keywords: Education Reform; Business And Society; Climate Change; Equality and Inequality; Environmental Sustainability; Business Education
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Hoffman, Andrew J. "Business Education Is Broken: Here Are Strategies to Fix It." Inspiring Minds (May 9, 2024).
  • March 2018 (Revised May 2018)
  • Supplement

Celgene (B)

By: Malcolm Baker and Emily McComb
Supplements the (A) case. View Details
Keywords: Life Sciences; Biotechnology; Public Market Investing; Celgene; Revlimid; Hedge Fund; Growth Stocks; Valuation; Investment; Decision Choices and Conditions; Analysis; Biotechnology Industry
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Baker, Malcolm, and Emily McComb. "Celgene (B)." Harvard Business School Supplement 218-099, March 2018. (Revised May 2018.)
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