Drug Trials - Publications - Faculty & Research

November 2007
Case

Antegren: A Beacon of Hope

By: Joshua D. Margolis, Thomas J. DeLong and Terence Heymann

The CEO of Biogen Idec faces a set of difficult decisions regarding a promising drug for Multiple Sclerosis that is headed for early approval by the FDA. The first in a series focuses on operational decisions triggered by the drive for early approval. Sparks discussion... View Details

Keywords: Demand and Consumers; Leadership; Ethics; Corporate Social Responsibility and Impact; Decision Choices and Conditions; Crisis Management; Health Testing and Trials; Biotechnology Industry; Pharmaceutical Industry

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April 2009 (Revised May 2010)
Case

Partners In Health: HIV Care in Rwanda

By: Michael E. Porter, Scott S. Lee, Joseph Rhatigan and Jim Yong Kim

In 2005, Partners in Health (PIH) was invited by the Rwandan Ministry of Health to assume responsibility for the management of public health care in two rural districts in Eastern Rwanda and create an HIV treatment program at these sites. PIH successfully implemented a... View Details

Keywords: Developing Countries and Economies; Health Care and Treatment; Health Testing and Trials; Medical Specialties; Service Delivery; Nonprofit Organizations; Expansion; Health Industry; Rwanda

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10 Oct 2007
First Look

First Look: First Look: October 10

broad-based therapies. Instead, the focus should be on enrolling subpopulations, based on diagnostic testing, in trials of targeted drug treatments and on monitoring and assessing effectiveness after View Details

Keywords: Martha Lagace

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Curriculum - Case Method Project

White Leagues and the Ku Klux Klan; ‘Redeemer’ Democrats; 1876 election; Compromise of 1877 Reconstruction B: Jury Rights in Virginia, 1877-1880 This case continues to examine some of the central issues of Reconstruction by focusing on a racially-charged murder View Details

21 Feb 2018
Research & Ideas

When a Competitor Abandons the Market, Should You Advance or Retreat?

Administration. He looked most closely at decisions made during phase two clinical trials—the period when diseased patients are treated with the test drug and results are compared with patients randomly receiving a placebo. The View Details

Keywords: by Rachel Layne; Pharmaceutical; Health

07 Feb 2024
News

The Sound of Success

A groundbreaking gene therapy developed by Akouos, Inc., a precision genetic medicine company founded in 2016 by Emmanuel (Manny) Simons (MBA 2012), has enabled an 11-year-old boy from Morocco to hear sounds for the first time. According to a recent New York Times... View Details

01 Dec 2023
News

Wide Horizon

IP rights for suramin, a century-old drug historically used to treat African sleeping sickness, a parasitic disease, and later tested as a treatment for metastatic cancer. N of One had supported a trial by... View Details

Keywords: Dan Morrell; Photos by Sarah Wilson

25 Jul 2023
Research & Ideas

Could a Business Model Help Big Pharma Save Lives and Profit?

Might Also Like: The FDA’s Speedy Drug Approvals Are Safe: A Win-Win for Patients and Pharma Innovation Curbing an Unlikely Culprit of Rising Drug Prices: Pharmaceutical Donations Buy-In from Black Patients... View Details

Keywords: by Esther Schrader; Pharmaceutical; Health

04 Apr 2024
News

The Making of a Medical Milestone

On March 16, doctors at the Massachusetts General Hospital made history when they successfully transplanted a kidney from a genetically modified pig to a living human. The groundbreaking procedure marked a significant milestone in animal-to-human transplant, or... View Details

Keywords: Margie Kelley

22 Feb 2024
News

Combat-Tested Cancer Coaching

our scientists would have the tissue to play with. Then we started developing new drugs and new trials coming into the MMR. So now fast forward. Here we are, we have 15 drugs... View Details

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Research - Health Care

medications? We study the health consequences of drug interruptions caused by large, abrupt, and arbitrary changes in price. Medicare’s prescription drug benefit as-if-randomly assigns 65-year-olds a View Details

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Skydeck - Alumni

Sensation Author and producer Jeff Norton (MBA 2003) on how his show Geek Girl became a Netflix hit—and what it tells us about success in the streaming era Basket Chase Baskits president and CEO Robin Kovitz (MBA 2007) on the tactics and the View Details

27 Feb 2019
Research & Ideas

The Hidden Cost of a Product Recall

Evidence from Medical Device Firms, released in January. Bigger recalls, bigger reactions Using 13 years of US Food and Drug Administration data and a novel set of competitor classification algorithms, the team created a detailed history... View Details

Keywords: by Danielle Kost; Manufacturing; Consumer Products; Auto; Medical Devices & Supplies

09 Oct 2020
Blog Post

4 Things To Know About the MS/MBA Biotech

paying a stream of medical bills. My aversion to health care growing up, juxtaposed by the cost-free, quality care I received later in life as a US citizen, is why I want to work towards improving the health care system. I studied Biology in undergrad and developed a... View Details

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Rare Disease Day – Small Numbers, Big Challenges… and Big Opportunities - Blog: Health Supplement

Practitioners Topics Topics Biotech/pharma Care Delivery Clinical Trials Digital Health Global Health Health Care Entrepreneurship Health Care Innovation Health Care Investment Health Care at HBS Insurance/payor Medical... View Details

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Winners & Runners-Up | New Venture Competition

Venture Competition Runner-Up, Business Track: Sanso Sanso is helping drug manufacturers produce life-saving biologics more efficiently, in order to deliver cheaper drugs to patients worldwide. Team: Narek... View Details

31 Jan 2014
News

Body, Heal Thyself

molecules responsible for transporting DNA code from a cell's nucleus to the ribosomes that create proteins. mRNA Therapeutics, as the company calls this new drug application, gives patients' cells the code they need to begin creating... View Details

Keywords: Maureen Harmon; biotech; Health, Social Assistance; Scientific Research and Development Services

21 Feb 2023
Research & Ideas

What's Missing from the Racial Equity Dialogue?

Stanford University’s Center for Advanced Study in the Behavioral Sciences. He studies the relationship among incarceration, employment, and entrepreneurship. You Might Also Like: The Color of Private Equity: Quantifying the Bias Black Investors Face Buy-In from Black... View Details

Keywords: by Danielle Kost

31 May 2023
News

Alumni Achievement Awards 2023

came to Vertex in 2017, there was a medicine finishing early clinical trials with the potential to serve up to 90 percent of patients with cystic fibrosis (CF). In October 2019 that became Trikafta. Now CF patients talk to me about... View Details

Keywords: leadership; management; work-life balance

01 Jun 2023
News

Research Brief: The Best Medicine

the clinical approval process. In a survey experiment, the researchers found that 72 percent of doctors had been asked by their patients whether a new drug would “work in people like me.” Black patients and the doctors who treat them put... View Details

Keywords: Jen McFarland Flint; Hospitals; Health, Social Assistance

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