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- All HBS Web
(5,461)
- Faculty Publications (894)
- January 2023
- Case
Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery
By: Regina Herzlinger and Brian Walker
What should a successful executive (HBS Baker Scholar) assess as her next move as the CEO of a firm with a promising and yet uncertain new drug? Amy Burroughs’ mandate to successfully commercialize Cleave Therapeutics’ drug for a cancer with no current successful... View Details
Keywords: Product Development; Leadership; Health Testing and Trials; Research and Development; Risk and Uncertainty; Financial Condition; Partners and Partnerships; Pharmaceutical Industry
Herzlinger, Regina, and Brian Walker. "Cleave Therapeutics: Taking a Risk on Oncology Drug Discovery." Harvard Business School Case 323-045, January 2023.
- December 2022 (Revised June 2023)
- Case
Hacking the U.S. Election: Russia's Misinformation Campaign
By: Shikhar Ghosh
The case discusses the relatively low technology approach used by Russia to influence the U.S. Presidential Election in 2016. Although political parties manipulating the media was not a new phenomenon, the Russians ran a broad, well-financed, and sophisticated social... View Details
Keywords: Political Elections; International Relations; Social Media; Power and Influence; Information; Russia; United States
Ghosh, Shikhar. "Hacking the U.S. Election: Russia's Misinformation Campaign." Harvard Business School Case 823-043, December 2022. (Revised June 2023.)
- 2022
- Article
Becoming a Learning Organization While Enhancing Performance: The Case of LEGO
By: Thomas Borup Kristensen, Henrik Saabye and Amy Edmondson
Purpose - The purpose of this study is to empirically test how problem-solving lean practices, along with
leaders as learning facilitators in an action learning approach, can be transferred from a production context to a
knowledge work context for the purpose... View Details
Kristensen, Thomas Borup, Henrik Saabye, and Amy Edmondson. "Becoming a Learning Organization While Enhancing Performance: The Case of LEGO." International Journal of Operations & Production Management 42, no. 13 (2022): 438–481.
- December 2022
- Article
The Contribution of Price Growth to Pharmaceutical Revenue Growth in the United States: Evidence from Medicines Sold in Retail Pharmacies
By: Pragya Kakani, Michael Chernew and Amitabh Chandra
Context: To what extent does pharmaceutical revenue growth depend on new medicines versus increasing prices for existing medicines? Moreover, does using list prices, as is commonly done, instead of prices net of confidential rebates offered by manufacturers, which are... View Details
Kakani, Pragya, Michael Chernew, and Amitabh Chandra. "The Contribution of Price Growth to Pharmaceutical Revenue Growth in the United States: Evidence from Medicines Sold in Retail Pharmacies." Journal of Health Politics, Policy and Law 47, no. 6 (December 2022): 629–648.
- December 2022
- Article
The Rise of People Analytics and the Future of Organizational Research
By: Jeff Polzer
Organizations are transforming as they adopt new technologies and use new sources of data, changing the experiences of employees and pushing organizational researchers to respond. As employees perform their daily activities, they generate vast digital data. These data,... View Details
Keywords: Organizational Change and Adaptation; Analytics and Data Science; Technology Adoption; Employees
Polzer, Jeff. "The Rise of People Analytics and the Future of Organizational Research." Art. 100181. Research in Organizational Behavior 42 (December 2022). (Supplement.)
- 2022
- Article
Which Explanation Should I Choose? A Function Approximation Perspective to Characterizing Post hoc Explanations
By: Tessa Han, Suraj Srinivas and Himabindu Lakkaraju
A critical problem in the field of post hoc explainability is the lack of a common foundational goal among methods. For example, some methods are motivated by function approximation, some by game theoretic notions, and some by obtaining clean visualizations. This... View Details
Han, Tessa, Suraj Srinivas, and Himabindu Lakkaraju. "Which Explanation Should I Choose? A Function Approximation Perspective to Characterizing Post hoc Explanations." Advances in Neural Information Processing Systems (NeurIPS) (2022). (Best Paper Award, International Conference on Machine Learning (ICML) Workshop on Interpretable ML in Healthcare.)
- November 2022
- Article
Measuring Inequality beyond the Gini Coefficient May Clarify Conflicting Findings
By: Kristin Blesch, Oliver P. Hauser and Jon M. Jachimowicz
Prior research has found mixed results on how economic inequality is related to various outcomes. These contradicting findings may in part stem from a predominant focus on the Gini coefficient, which only narrowly captures inequality. Here, we conceptualize the... View Details
Keywords: Economic Inequalty; Gini Coefficient; Income Inequality; Equality and Inequality; Social Issues; Health; Status and Position
Blesch, Kristin, Oliver P. Hauser, and Jon M. Jachimowicz. "Measuring Inequality beyond the Gini Coefficient May Clarify Conflicting Findings." Nature Human Behaviour 6, no. 11 (November 2022): 1525–1536.
- October–December 2022
- Article
Achieving Reliable Causal Inference with Data-Mined Variables: A Random Forest Approach to the Measurement Error Problem
By: Mochen Yang, Edward McFowland III, Gordon Burtch and Gediminas Adomavicius
Combining machine learning with econometric analysis is becoming increasingly prevalent in both research and practice. A common empirical strategy involves the application of predictive modeling techniques to "mine" variables of interest from available data, followed... View Details
Keywords: Machine Learning; Econometric Analysis; Instrumental Variable; Random Forest; Causal Inference; AI and Machine Learning; Forecasting and Prediction
Yang, Mochen, Edward McFowland III, Gordon Burtch, and Gediminas Adomavicius. "Achieving Reliable Causal Inference with Data-Mined Variables: A Random Forest Approach to the Measurement Error Problem." INFORMS Journal on Data Science 1, no. 2 (October–December 2022): 138–155.
- 2022
- Book
Healthy Buildings: How Indoor Spaces Can Make You Sick—or Keep You Well
By: Joseph G. Allen and John D. Macomber
For too long we’ve designed buildings that haven’t focused on the people inside—their health, their ability to work effectively, and what that means for the bottom line. An authoritative introduction to a movement whose vital importance is now all too clear, Healthy... View Details
Allen, Joseph G., and John D. Macomber. Healthy Buildings: How Indoor Spaces Can Make You Sick—or Keep You Well. Revised and updated edition, Cambridge, MA: Harvard University Press, 2022.
- 2022
- Article
Data Poisoning Attacks on Off-Policy Evaluation Methods
By: Elita Lobo, Harvineet Singh, Marek Petrik, Cynthia Rudin and Himabindu Lakkaraju
Off-policy Evaluation (OPE) methods are a crucial tool for evaluating policies in high-stakes domains such as healthcare, where exploration is often infeasible, unethical, or expensive. However, the extent to which such methods can be trusted under adversarial threats... View Details
Lobo, Elita, Harvineet Singh, Marek Petrik, Cynthia Rudin, and Himabindu Lakkaraju. "Data Poisoning Attacks on Off-Policy Evaluation Methods." Proceedings of the Conference on Uncertainty in Artificial Intelligence (UAI) 38th (2022): 1264–1274.
- 2022
- Article
Fairness via Explanation Quality: Evaluating Disparities in the Quality of Post hoc Explanations
By: Jessica Dai, Sohini Upadhyay, Ulrich Aivodji, Stephen Bach and Himabindu Lakkaraju
As post hoc explanation methods are increasingly being leveraged to explain complex models in high-stakes settings, it becomes critical to ensure that the quality of the resulting explanations is consistently high across all subgroups of a population. For instance, it... View Details
Dai, Jessica, Sohini Upadhyay, Ulrich Aivodji, Stephen Bach, and Himabindu Lakkaraju. "Fairness via Explanation Quality: Evaluating Disparities in the Quality of Post hoc Explanations." Proceedings of the AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society (2022): 203–214.
- 2022
- Article
Nonparametric Subset Scanning for Detection of Heteroscedasticity
By: Charles R. Doss and Edward McFowland III
We propose Heteroscedastic Subset Scan (HSS), a novel method for identifying covariates that are responsible for violations of the homoscedasticity assumption in regression settings. Viewing the problem as one of anomalous pattern detection, we use subset scanning... View Details
Doss, Charles R., and Edward McFowland III. "Nonparametric Subset Scanning for Detection of Heteroscedasticity." Journal of Computational and Graphical Statistics 31, no. 3 (2022): 813–823.
- 2022
- Article
Towards Robust Off-Policy Evaluation via Human Inputs
By: Harvineet Singh, Shalmali Joshi, Finale Doshi-Velez and Himabindu Lakkaraju
Off-policy Evaluation (OPE) methods are crucial tools for evaluating policies in high-stakes domains such as healthcare, where direct deployment is often infeasible, unethical, or expensive. When deployment environments are expected to undergo changes (that is, dataset... View Details
Singh, Harvineet, Shalmali Joshi, Finale Doshi-Velez, and Himabindu Lakkaraju. "Towards Robust Off-Policy Evaluation via Human Inputs." Proceedings of the AAAI/ACM Conference on Artificial Intelligence, Ethics, and Society (2022): 686–699.
- June 2022
- Article
The Use and Misuse of Patent Data: Issues for Finance and Beyond
By: Josh Lerner and Amit Seru
Patents and citations are powerful tools for understanding innovation increasingly used in financial economics (and management research more broadly). Biases may result, however, from the interactions between the truncation of patents and citations and the changing... View Details
Lerner, Josh, and Amit Seru. "The Use and Misuse of Patent Data: Issues for Finance and Beyond." Review of Financial Studies 35, no. 6 (June 2022): 2667–2704.
- 2022
- Article
Exploring Counterfactual Explanations Through the Lens of Adversarial Examples: A Theoretical and Empirical Analysis.
By: Martin Pawelczyk, Chirag Agarwal, Shalmali Joshi, Sohini Upadhyay and Himabindu Lakkaraju
As machine learning (ML) models become more widely deployed in high-stakes applications, counterfactual explanations have emerged as key tools for providing actionable model explanations in practice. Despite the growing popularity of counterfactual explanations, a... View Details
Keywords: Machine Learning Models; Counterfactual Explanations; Adversarial Examples; Mathematical Methods
Pawelczyk, Martin, Chirag Agarwal, Shalmali Joshi, Sohini Upadhyay, and Himabindu Lakkaraju. "Exploring Counterfactual Explanations Through the Lens of Adversarial Examples: A Theoretical and Empirical Analysis." Proceedings of the International Conference on Artificial Intelligence and Statistics (AISTATS) 25th (2022).
- Article
How Much Should We Trust Staggered Difference-In-Differences Estimates?
By: Andrew C. Baker, David F. Larcker and Charles C.Y. Wang
We explain when and how staggered difference-in-differences regression estimators, commonly applied to assess the impact of policy changes, are biased. These biases are likely to be relevant for a large portion of research settings in finance, accounting, and law that... View Details
Keywords: Difference In Differences; Staggered Difference-in-differences Designs; Generalized Difference-in-differences; Dynamic Treatment Effects; Mathematical Methods
Baker, Andrew C., David F. Larcker, and Charles C.Y. Wang. "How Much Should We Trust Staggered Difference-In-Differences Estimates?" Journal of Financial Economics 144, no. 2 (May 2022): 370–395. (Editor's Choice, May 2022; Jensen Prize, First Place, June 2023.)
- 2022
- Article
Probing GNN Explainers: A Rigorous Theoretical and Empirical Analysis of GNN Explanation Methods.
By: Chirag Agarwal, Marinka Zitnik and Himabindu Lakkaraju
As Graph Neural Networks (GNNs) are increasingly employed in real-world applications, it becomes critical to ensure that the stakeholders understand the rationale behind their predictions. While several GNN explanation methods have been proposed recently, there has... View Details
Keywords: Graph Neural Networks; Explanation Methods; Mathematical Methods; Framework; Theory; Analysis
Agarwal, Chirag, Marinka Zitnik, and Himabindu Lakkaraju. "Probing GNN Explainers: A Rigorous Theoretical and Empirical Analysis of GNN Explanation Methods." Proceedings of the International Conference on Artificial Intelligence and Statistics (AISTATS) 25th (2022).
- April 12, 2022
- Article
Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States
By: Estee Y. Cramer, Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li and et al.
Short-term probabilistic forecasts of the trajectory of the COVID-19 pandemic in the United States have served as a visible and important communication channel between the scientific modeling community and both the general public and decision-makers. Forecasting models... View Details
Keywords: COVID-19; Forecasting and Prediction; Health Pandemics; Mathematical Methods; Partners and Partnerships
Cramer, Estee Y., Evan L. Ray, Velma K. Lopez, Johannes Bracher, Andrea Brennen, Alvaro J. Castro Rivadeneira, Michael Lingzhi Li, and et al. "Evaluation of Individual and Ensemble Probabilistic Forecasts of COVID-19 Mortality in the United States." e2113561119. Proceedings of the National Academy of Sciences 119, no. 15 (April 12, 2022). (See full author list here.)
- 2022
- Working Paper
A Linear Panel Model with Heterogeneous Coefficients and Variation in Exposure
By: Jesse M. Shapiro and Liyang Sun
Linear panel models featuring unit and time fixed effects appear in many areas of empirical economics. An active literature studies the interpretation of the ordinary least squares estimator of the model, commonly called the two-way fixed effects (TWFE) estimator, in... View Details
Shapiro, Jesse M., and Liyang Sun. "A Linear Panel Model with Heterogeneous Coefficients and Variation in Exposure." NBER Working Paper Series, No. 29976, April 2022.
- April 2022
- Article
Predictable Financial Crises
Using historical data on post-war financial crises around the world, we show that crises are substantially predictable. The combination of rapid credit and asset price growth over the prior three years, whether in the nonfinancial business or the household sector, is... View Details
Greenwood, Robin, Samuel G. Hanson, Andrei Shleifer, and Jakob Ahm Sørensen. "Predictable Financial Crises." Journal of Finance 77, no. 2 (April 2022): 863–921.