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  • August 2023
  • Case

Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company

By: Satish Tadikonda and Brad Prosek
Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
Keywords: Mergers and Acquisitions; Health Care and Treatment; Organizational Change and Adaptation; Research and Development; Business Strategy; Partners and Partnerships; Goals and Objectives; Pharmaceutical Industry; United States
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  • Article

Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting

By: Raymond H. Mak, Michael G. Endres, Jin Hyun Paik, Rinat A. Sergeev, Hugo Aerts, Christopher L. Williams, Karim R. Lakhani and Eva C. Guinan
Importance: Radiation therapy (RT) is a critical cancer treatment, but the existing radiation oncologist work force does not meet growing global demand. One key physician task in RT planning involves tumor segmentation for targeting, which requires substantial... View Details
Keywords: Crowdsourcing; AI Algorithms; Health Care and Treatment; Collaborative Innovation and Invention; AI and Machine Learning
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  • March 2008 (Revised June 2008)
  • Case

The Broad Institute: Applying the Power of Genomics to Medicine

By: Vicki L. Sato and Rachel Gordon
In June 2003, Harvard University and MIT announced an unprecedented partnership to create a biomedical institute, The Broad Institute. The culture of the Broad centered on science, and those involved considered it to be at the edge of the scientific frontier. In just... View Details
Keywords: Education; Health Care and Treatment; Innovation Leadership; Growth and Development Strategy; Organizational Culture; Partners and Partnerships; Research and Development; Genetics
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  • May 2012 (Revised August 2014)
  • Case

McKesson

By: Regina E. Herzlinger and Natalie Kindred
McKesson, a large, diversified drug distribution and health care IT company, is considering development of new business offerings to help private practice physicians remain independent. The company, with $122 billion in 2010 revenues, just made its first foray into... View Details
Keywords: Health Care Industry; Health Care Policy; Organizational Transformations; Health Services; Health Care and Treatment; Business Model; Service Operations; Change Management; Corporate Strategy; Information Technology; Policy; Pharmaceutical Industry; Health Industry; United States
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  • April 2021
  • Article

Utilizing Time-driven Activity-based Costing to Determine Open Radical Cystectomy and Ileal Conduit Surgical Episode Cost Drivers

By: Janet Baack Kukreja, Mohamed A. Seif, Marissa W. Merry, James R. Incalcaterra, Ashish M. Kamat, Colin P. Dinney, Jay B. Shah, Thomas W. Feeley and Neema Navai
Objectives
Patients undergoing radical cystectomy represent a particularly resource-intensive patient population. Time-driven activity based costing (TDABC) assigns time to events and then costs are based on the people involved in providing care for specific... View Details
Keywords: Time-Driven Activity-Based Costing; Value-based Healthcare; Health Care and Treatment; Cost; Cost vs Benefits; Analysis
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  • 22 Mar 2021
  • Research & Ideas

How to Learn from the Big Mistake You Almost Make

For example, providers must check cancer patients undergoing radiation for pacemakers, which can malfunction during the treatment. Employees were asked to rank the likelihood that they would report the following near-miss scenarios, which... View Details
Keywords: by Kristen Senz; Health
  • 22 Aug 2022
  • Research & Ideas

Can Amazon Remake Health Care?

know how to land a human on Mars. The sobering reality of health care is that terrible things—Alzheimer’s or cancer or an accident—can happen to anyone, including very healthy people. And that’s the bulk of health care spending. The... View Details
Keywords: by Christina Pazzanese, Harvard Gazette; Health
  • 17 Feb 2022
  • Book

When Employees Feel a Sense of Purpose, Companies Succeed

worth living, while others took the opportunity to divulge very personal information. In one case, a female employee shocked her colleagues by relating that she had breast cancer and had been having View Details
Keywords: by Ranjay Gulati
  • 25 Jun 2007
  • Research & Ideas

HBS Cases: Beauty Entrepreneur Madam Walker

nourished and lived in conditions of poor hygiene and constant labor. Hair loss was psychologically debilitating for early 20th-century women, as it is today for female cancer patients enduring the ordeals of chemotherapy, for instance,... View Details
Keywords: by Martha Lagace; Beauty & Cosmetics
  • 19 Sep 2016
  • Research & Ideas

Why Isn't Business Research More Relevant to Business Practitioners?

treatment in Microsoft Word. (Case in point, see above: “Egocentric Interpretations of Fairness in Asymmetric, Environmental Social Dilemmas: Explaining Harvesting Behavior and the Role of Communication” vs. “The Impossibility of Auditor... View Details
Keywords: by Carmen Nobel; Education
  • 07 Aug 2000
  • Research & Ideas

The Business of Biotech

cancer and AIDS. Those working in the biotech trenches, however, point out that the real work has only just begun. Dr. Robert Tepper, chief scientific officer for Millennium Pharmaceuticals, Inc., put it this way in a Business Week... View Details
Keywords: by Julia Hanna; Biotechnology; Health; Technology
  • 22 May 2020
  • In Practice

Post-COVID Health Care: More Screens, Less Red Tape?

precision diagnostics. It is a travesty that we don’t have simple tests that can distinguish between the common cold, seasonal allergies, and various strains of the flu, let alone the sophisticated diagnostics needed to guide the View Details
Keywords: by Danielle Kost
  • 29 May 2001
  • Research & Ideas

Genomics: Can We Start Making Money Now?

predict a new world where drug treatments are customized to an individual's genetic makeup, and gene-based therapy can root out cancer and other diseases before they take hold in the body. The new science... View Details
Keywords: by Sean Silverthorne
  • 03 Dec 2001
  • Research & Ideas

Healthcare Conference Looks At Ailing Industry

Cancer research, it has been said, is not unlike a group of blind men studying an elephant. One man feels the elephant's tail and says it is a rope. Another blind man handles its tusk and calls it a spear, and yet another declares its... View Details
Keywords: by Martha Lagace; Health
  • 29 Mar 2016
  • First Look

March 29, 2016

dynamic capture of these metrics via our new electronic health record (EHR) was developed at our institution. Methods. Contemporary breast cancer literature on treatment options, expected outcomes, and... View Details
Keywords: Sean Silverthorne
  • 03 Jun 2014
  • First Look

First Look: June 3

this proposal, and what other options may be available. Purchase this case: http://hbr.org/product/school-specialty-inc/an/214084-PDF-ENG Harvard Business School Case 314-003 Cancer Treatment Centers of... View Details
Keywords: Sean Silverthorne
  • 14 Dec 2020
  • Research & Ideas

What Does December's Drug-Approval Dash Mean for COVID-19 Vaccines?

Pharmaceutical regulators around the world tend to speed through drug applications in December and before major national holidays, according to new research that might raise questions about COVID-19 vaccines and other treatments under... View Details
Keywords: by Danielle Kost; Pharmaceutical; Health
  • 20 Sep 2016
  • First Look

September 20, 2016

years before The Wealth of Nations. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=51625 forthcoming Journal of Oncology Practice Communicating Value in Healthcare Using Radar Charts: A Case Study of Prostate Cancer By:... View Details
Keywords: Sean Silverthorne
  • 26 Jun 2012
  • First Look

First Look: June 26

MaterialsCancer Treatment Centers of America®: Scaling the Mother Standard® of Care Rosabeth Moss Kanter and Matthew BirdHarvard Business School Case 312-073 The CEO of a private and growing national network of specialty care hospitals... View Details
Keywords: Sean Silverthorne
  • 13 May 2014
  • First Look

First Look: May 13

University Hospital, Martini was a "hospital in a hospital" in close proximity to other hospital departments and services. By 2013, Martini Klinik had become the largest prostate cancer treatment... View Details
Keywords: Sean Silverthorne

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