Publications

September 2019
Supplement

Adaptive Platform Trials: The Clinical Trial of the Future? (B)

By: Ariel D. Stern and Sarah Mehta

This case provides an update to the (A) case, which introduces students to adaptive platform trials, an ambitious, more efficient type of clinical trial that increases access to therapies. The (A) case centers on Dr. Brian Alexander’s efforts to launch an adaptive... View Details

Keywords: Clinical Trials; Drug Trials; Drug Testing; Cancer Trials; Glioblastoma; Platform Trials; Adaptive Trials; Adaptive Platform Trials; Health Testing and Trials; Health Care and Treatment; Financing and Loans; Business Strategy; Health Industry; United States

March 2018
Teaching Note

Adaptive Platform Trials: The Clinical Trial of the Future?

By: Ariel D. Stern and Sarah Mehta

This teaching note provides guidance and recommendations for teaching HBS Case No. 618-025, entitled “Adaptive Platform Trials: The Clinical Trial of the Future?” View Details

Keywords: Clinical Trials; Drug Trials; Drug Testing; Cancer Trials; Glioblastoma; Platform Trials; Adaptive Trials; Adaptive Platform Trials; Health Testing and Trials; Health Care and Treatment; Business Strategy; Health Industry; United States

January 2011 (Revised March 2011)
Case

Predictive Biosciences

By: Thomas R. Eisenmann, Jeffrey J. Bussgang and David Kiron

A small cancer diagnostics start-up is deciding whether to acquire a laboratory to make and sell its bladder cancer test or build its own manufacturing and sales team. View Details

Keywords: Mergers and Acquisitions; Factories, Labs, and Plants; Business Startups; Entrepreneurship; Health Testing and Trials; Growth and Development Strategy; Product Development; Biotechnology Industry

07 Jun 2016
First Look

June 7, 2016

strategic, financial, and operational objectives. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=51110 May 2016 Oncology How the Affordable Care Act Has Affected Cancer Care in the United States: Has Value for View Details

Keywords: Sean Silverthorne

February 1994 (Revised May 1999)
Case

Manville Corp. Fiber Glass Group (C)

By: Lynn S. Paine and Sarah Gant

Manville Corp.'s senior managers are surprised when Japanese government officials advise them not to go forward with their plan to add a cancer warning label to diatomaceous earth (DE) products sold in Japan. The International Agency for Research on Cancer has ruled... View Details

Keywords: Management Teams; Ethics; Conflict of Interests; Health; Safety; Cross-Cultural and Cross-Border Issues; Policy; Japan

August 2011 (Revised September 2011)
Supplement

The Dannon Company: Marketing and Corporate Social Responsibility (B)

By: Christopher Marquis and Bobbi Thomason

Details Dannon's decision to initiate a cause marketing program focused on breast cancer to directly compete with Yoplait. View Details

Keywords: Marketing; Corporate Social Responsibility and Impact; Food and Beverage Industry

November 2005 (Revised March 2006)
Case

Genentech - Capacity Planning

By: Daniel C. Snow, Steven C. Wheelwright and Alison Berkley Wagonfeld

While facilitating a complex clinical approval process over the next two to three years for a family of new cancer drugs, Genentech must develop a long-term capacity plan for a major class of new cancer products. Adding to the complexity and uncertainty is the fact... View Details

Keywords: Factories, Labs, and Plants; Growth and Development Strategy; Management Style; Management Teams; Time Management; Product; Product Development; Business Processes; Performance Capacity; Planning; Risk and Uncertainty; Complexity; Pharmaceutical Industry

December 2003
Case

Manville Corporation Fiber Glass Group (C) (Abridged)

By: Lynn S. Paine

Manville Corp.'s senior managers are surprised when Japanese government officials advise them not to go forward with their plan to add a cancer warning label to diatomaceous earth (DE) products sold in Japan. The International Agency for Research on Cancer has ruled... View Details

Keywords: Risk and Uncertainty; Moral Sensibility; Safety; Government Administration; Cross-Cultural and Cross-Border Issues; Decision Choices and Conditions; Ethics; Announcements; Industrial Products Industry; Japan

Teaching Interest

Health Systems

Instructor, Pasteur Institute CNAM School of Public Health (Paris, France), Mid-Career professionals from the National Institute of Cancer (INCA) View Details

Keywords: Health; Health Care; Health Care Delivery; Health Care Reform; Health Care Industry

February 2023
Supplement

Dr. Andrea Pusic, Video Supplement

By: Robert S. Kaplan

Video supplement to aid in the teaching of "Brigham & Women's Hospital: Using Patient Reported Outcomes to Improve Breast Cancer Care," HBS case no. 122-010. View Details

October 2013
Case

FasterCures: Removing Barriers to Treatments

By: Richard G. Hamermesh and James Weber

In mid-2013, as FasterCures celebrated its 10th anniversary as a center of the Milken Institute, Executive Director Margaret Anderson thought about what the organization should do to ensure it had even more impact in its next 10 years. FasterCures was a non-profit... View Details

30 Aug 2016
First Look

August 30, 2016

experiences instead of possessions. Similarly, people enjoy greater happiness from spending time on or with others and from acquiring experiences—both extraordinary and ordinary. Publisher's link: https://www.hbs.edu/faculty/Pages/item.aspx?num=51544 August 17, 2016... View Details

Keywords: Carmen Nobel

January 2001
Case

Abgenix and the XenoMouse

By: Robert J. Dolan

Abgenix has a unique method for generating antibodies useful in treating a number of diseases, including cancer. In early 2000, the company's cancer has performed very well in animal testing and is moving to early stage human testing. Abgenix must decide whether to... View Details

Keywords: Product Development; Marketing Strategy; Health Testing and Trials; Risk and Uncertainty; Technological Innovation; Innovation Strategy; Science-Based Business; Biotechnology Industry

July 2014
Article

Second-Opinion Pathologic Review is a Patient Safety Mechanism That Helps Reduce Error and Decrease Waste

By: Lavinia Middleton, Thomas W. Feeley, Heidi W. Albright, Ronald Walters and Stanley Hamilton

We have a crisis in health care delivery, originating from increasing health care costs and inconsistent quality-of-care measures. During the past several years, value-based health care delivery has gained increasing attention as an approach to control costs and... View Details

Keywords: Pathology; Diagnostic Errors; Health Care and Treatment; Health Industry; North and Central America

Read Now

September 2020
Case

Minerva 2010: Turbulent Times

By: John R. Wells and Benjamin Weinstock

In 2010, amid a flurry of new discoveries, Cynthia Bamdad, founder and CEO of Minerva Biotechnologies Corporation (Minerva), raised $6.6 million to test her new cancer drugs in mice. It had been more than 6 years since she had announced that she and her small team at... View Details

Keywords: Biotechnology; Research; Product Development; Commercialization; Strategy

October 2021 (Revised February 2022)
Case

Hospital 57357: Aligning Performance Towards a Vision of a Cancer-Free Childhood

By: Susanna Gallani and Youssef Abdel Aal

The case follows the Children Cancer Hospital in Egypt, also known as Hospital 57357, as it goes through the roll-out of a new performance management system, which Dr. Sherif Abouel Naga, founder and CEO of the hospital, had championed. This was a critical juncture as... View Details

Keywords: Healthcare; Performance Management; Performance Incentives; Strategic Alignment; Health Care and Treatment; Nonprofit Organizations; Strategy; Alignment; Performance Evaluation; Mission and Purpose; Change Management; Health Industry; Egypt; Middle East

November 2009 (Revised August 2010)
Case

NovoCure Ltd.

By: William A. Sahlman and Sarah Flaherty

Venture capitalist William Doyle must raise $35 million for a portfolio company with a promising, novel cancer therapy, just as global capital markets are imploding in the fall of 2008. NovoCure, Ltd., has developed an electrical-field-based therapy, called Tumor... View Details

Keywords: Financial Crisis; Entrepreneurship; Venture Capital; Investment; Health Care and Treatment; Health Testing and Trials; Technological Innovation; Financial Services Industry