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      • September 2023 (Revised December 2023)
      • Case

      TetraScience: Noise and Signal

      By: Thomas R. Eisenmann and Tom Quinn
      In 2019, TetraScience CEO “Spin” Wang needed advice. Five years earlier, he had cofounded a startup that saw early success with a hardware product designed to help laboratory scientists in the biotechnology and pharmaceutical spaces more easily collect data from... View Details
      Keywords: Entrepreneurship; Business Growth and Maturation; Business Organization; Restructuring; Forecasting and Prediction; Digital Platforms; Analytics and Data Science; AI and Machine Learning; Organizational Structure; Network Effects; Competitive Strategy; Biotechnology Industry; Pharmaceutical Industry; United States; Boston
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      Eisenmann, Thomas R., and Tom Quinn. "TetraScience: Noise and Signal." Harvard Business School Case 824-024, September 2023. (Revised December 2023.)
      • September 2023 (Revised April 2024)
      • Case

      Atomwise: Strategic Opportunities in AI for Pharma

      By: Satish Tadikonda
      Abraham Heifets and his co-founder, Izhar Wallach, had founded Atomwise to develop i) an AI engine to transform drug discovery by creating better medicines faster, and ii) a machine learning-based discovery engine that combined the power of convolutional neural... View Details
      Keywords: Business Model; Business Startups; AI and Machine Learning; Science-Based Business; Technological Innovation; Biotechnology Industry; Pharmaceutical Industry
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      Tadikonda, Satish. "Atomwise: Strategic Opportunities in AI for Pharma." Harvard Business School Case 824-043, September 2023. (Revised April 2024.)
      • September 2023 (Revised January 2024)
      • Case

      RightHand Robotics: Choosing the First Market

      By: Thomas R. Eisenmann and Stacy Straaberg
      In early 2015, RightHand Robotics’s (RHR) leadership faced a set of decisions in commercializing the startup’s robotic picking solution. RHR’s central product was the RightPick integrated robotic picking system which featured a robotic arm, a three-fingered robotic... View Details
      Keywords: Business Startups; Market Entry and Exit; Product; Research and Development; Business Strategy; Commercialization; Information Infrastructure; Technological Innovation; Manufacturing Industry; Technology Industry; United States; Massachusetts
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      Eisenmann, Thomas R., and Stacy Straaberg. "RightHand Robotics: Choosing the First Market." Harvard Business School Case 824-006, September 2023. (Revised January 2024.)
      • 2023
      • Book

      Right Kind of Wrong: The Science of Failing Well

      By: Amy Edmondson
      A revolutionary guide that will transform your relationship with failure, from the pioneering researcher of psychological safety and award-winning Harvard Business School professor Amy Edmondson.

      We used to think of failure as the opposite of success. Now,... View Details
      Keywords: Failure; Success
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      Edmondson, Amy. Right Kind of Wrong: The Science of Failing Well. New York, NY: Atria Books, 2023.
      • September–October 2023
      • Article

      The New Era of Industrial Policy Is Here

      By: Willy C. Shih
      Governments around the world are increasingly intervening in the private sector through industrial policies designed to help domestic sectors reach goals that markets alone are unlikely to achieve. Companies in targeted sectors—such as automakers, energy companies, and... View Details
      Keywords: Policy; Government and Politics; Business and Government Relations; Research and Development; Economic Sectors
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      Shih, Willy C. "The New Era of Industrial Policy Is Here." Harvard Business Review 101, no. 5 (September–October 2023): 66–75.
      • 2023
      • Working Paper

      Mapping Organizational-Level Networks Using Individual-Level Connections: Evidence from Online Professional Networks

      By: Shelley Xin Li, Frank Nagle and Aner Zhou
      Organization-level networks facilitate the flow of information and business activities in the economy. Prior research relies solely on high-level connections to measure these networks. Therefore, to understand the role of employee connections at all job levels in... View Details
      Keywords: Networks; Value; Social and Collaborative Networks; Innovation and Invention; Knowledge Sharing; Employees; Social Media
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      Li, Shelley Xin, Frank Nagle, and Aner Zhou. "Mapping Organizational-Level Networks Using Individual-Level Connections: Evidence from Online Professional Networks." Harvard Business School Working Paper, No. 24-010, August 2023.
      • August 2023
      • Case

      Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company

      By: Satish Tadikonda and Brad Prosek
      Constellation Pharmaceuticals was a company focused on epigenetic therapies for cancer patients. Despite a promising start and an early deal with a leading biopharma company, the company weathered twin setbacks in the end of a major research collaboration and the... View Details
      Keywords: Mergers and Acquisitions; Health Care and Treatment; Organizational Change and Adaptation; Research and Development; Business Strategy; Partners and Partnerships; Goals and Objectives; Pharmaceutical Industry; United States
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      Tadikonda, Satish, and Brad Prosek. "Constellation Pharmaceuticals: Corporate Development at a Novel Therapeutic Company." Harvard Business School Case 824-032, August 2023.
      • August 2023 (Revised January 2024)
      • Case

      Jake Becraft and Strand Therapeutics: The Making of an Entrepreneur

      By: Satish Tadikonda, William Marks and Ananya Zutshi
      Jake Becraft, a PhD student at MIT disillusioned in pursuit of his dreams of becoming an academic, serendipitously finds himself discussing the potential commercial applications of his work with Tasuku Kitada, his former postdoctoral research mentor. The two decide to... View Details
      Keywords: Entrepreneurship; Business Startups; Business or Company Management
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      Tadikonda, Satish, William Marks, and Ananya Zutshi. "Jake Becraft and Strand Therapeutics: The Making of an Entrepreneur." Harvard Business School Case 824-046, August 2023. (Revised January 2024.)
      • 2025
      • Working Paper

      Residential Battery Storage - Reshaping the Way We Do Electricity

      By: Christian Kaps and Serguei Netessine
      In this paper, we aim to understand when private households invest in behind-the-meter battery storage next to rooftop solar and how those batteries impact households, the electricity market, and emissions. We answer three main research questions: 1) When do customers... View Details
      Keywords: Solar Power; Energy Storage; Technology And Innovation Management; Energy; Energy Policy; Renewable Energy; Technological Innovation; Innovation and Management; Energy Industry
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      Kaps, Christian, and Serguei Netessine. "Residential Battery Storage - Reshaping the Way We Do Electricity." Working Paper, February 2025.
      • July 2023 (Revised May 2024)
      • Case

      Vytal: Packaging-as-a-Service

      By: George Serafeim, Michael W. Toffel, Lena Duchene and Daniela Beyersdorfer
      The Germany-based startup Vytal operated the largest digital-native reusable packaging-as-a-service network globally, having raised nearly €15 million, established a large network of restaurant partners, and prevented the use of millions of single-use take-out food... View Details
      Keywords: Climate Risk; Digital; Platform Strategies; Data; Packaging; Sustainability; Start-up; Startup; Entrepreneur; Impact; Circular; Growth Strategy; Innovation; Environmental Sustainability; Innovation and Invention; Business Growth and Maturation; Growth and Development Strategy; Business Startups; Resource Allocation; Risk Management; Adoption; Strategy; Performance Productivity; Service Delivery; Service Operations; Supply Chain; Distribution; Entrepreneurship; Climate Change; Green Technology Industry; Service Industry; Retail Industry; Germany; Europe
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      Serafeim, George, Michael W. Toffel, Lena Duchene, and Daniela Beyersdorfer. "Vytal: Packaging-as-a-Service." Harvard Business School Case 124-007, July 2023. (Revised May 2024.)
      • July 2023
      • Case

      DayTwo: Going to Market with Gut Microbiome (Abridged)

      By: Ayelet Israeli
      DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
      Keywords: Business Startups; AI and Machine Learning; Nutrition; Market Entry and Exit; Product Marketing; Distribution Channels
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      Israeli, Ayelet. "DayTwo: Going to Market with Gut Microbiome (Abridged)." Harvard Business School Case 524-015, July 2023.
      • 18 Jul 2023
      • Interview

      Jeffrey Rayport on Product Market Fit, Profit Market Fit and Whiplash, and More

      By: Jeffrey F. Rayport and Doug Levin
      This episode of "Lessons from Startup Life" podcast features Jeffrey Rayport, Senior Lecturer of Business Administration at the Harvard Business School. Jeffrey specializes in teaching and researching growth-stage technology ventures and their scalability. Prior to... View Details
      Keywords: Scaling And Growth; Start-up; Diversity; Equity; Inclusion; Technology; Business Startups; Product Marketing; Business Growth and Maturation
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      "Jeffrey Rayport on Product Market Fit, Profit Market Fit and Whiplash, and More." Lessons from a Startup Life (podcast), July 18, 2023.
      • June 2023
      • Case

      Investing in the Climate Transition at Neuberger Berman

      By: George Serafeim and Benjamin Maletta
      By mid-2023, Neuberger Berman (NB), an active asset manager, had grown its assets under management to about half a trillion dollars and took pride in its client centricity and innovative spirit. Responding to client demand for investment products that integrated... View Details
      Keywords: Carbon Emissions; Sustainability; Decarbonization; Performance; Risk Assessment; Opportunities; Environmental Sustainability; Carbon Footprint; Business Analysis; Investing; Regulation; Asset Management; Investment Strategy; Climate Change; Transition; Analysis; Product Positioning; Strategy; Investment Portfolio; Financial Services Industry; Energy Industry
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      Serafeim, George, and Benjamin Maletta. "Investing in the Climate Transition at Neuberger Berman." Harvard Business School Case 123-092, June 2023.
      • June 2023
      • Article

      Can Purpose Foster Stakeholder Trust in Corporations

      By: Ranjay Gulati and Franz Wohlgezogen
      As part of institutional changes toward more responsible capitalism, firms increasingly articulate a purpose beyond simply profit as a central tenet of their governance. Management scholarship has noted the potential advantages of such purpose-focus for stakeholder... View Details
      Keywords: Stakeholder Management; Moral Identity; Mission and Purpose; Trust; Corporate Governance; Business and Stakeholder Relations
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      Gulati, Ranjay, and Franz Wohlgezogen. "Can Purpose Foster Stakeholder Trust in Corporations." Strategy Science 8, no. 2 (June 2023): 270–287.
      • June 2023
      • Article

      The Effect of Firms' Information Exposure on Safeguarding Employee Health: Evidence from COVID-19

      By: Lisa Yao Liu and Shirley Lu
      We show that information exposure through international business networks enables firms to take proactive measures that benefit employees and potentially the local community. Specifically, in the early days of COVID-19, firms that have business networks with China and... View Details
      Keywords: COVID-19 Pandemic; Networks; Knowledge Use and Leverage; Health Pandemics; Decision Choices and Conditions; Corporate Social Responsibility and Impact
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      Liu, Lisa Yao, and Shirley Lu. "The Effect of Firms' Information Exposure on Safeguarding Employee Health: Evidence from COVID-19." Journal of Accounting Research 61, no. 3 (June 2023): 891–933.
      • June 2023
      • Case

      Verve Therapeutics: Taking DNA Editing to Heart

      By: Shikhar Ghosh and Shweta Bagai
      Verve Therapeutics, a public biotech company based in Boston, created a novel approach to addressing cardiovascular disease (CVD) - a leading cause of deaths globally. The company's approach was a single shot treatment to permanently lower cholesterol, thus reducing... View Details
      Keywords: AI; Genetic Engineering; Medicine; Health Care and Treatment; Genetics; Innovation Strategy; Business and Stakeholder Relations; Medical Specialties; Innovation and Invention; Entrepreneurship; Biotechnology Industry
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      Ghosh, Shikhar, and Shweta Bagai. "Verve Therapeutics: Taking DNA Editing to Heart." Harvard Business School Case 823-113, June 2023.
      • May 2023 (Revised June 2023)
      • Case

      Novartis (A): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Leadership; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (A): Reimagining Medicine." Harvard Business School Case 723-443, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (B): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Care and Treatment; Business Model; Production; Business Strategy; Pharmaceutical Industry
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (B): Reimagining Medicine." Harvard Business School Supplement 723-444, May 2023. (Revised June 2023.)
      • May 2023 (Revised June 2023)
      • Supplement

      Novartis (C): Reimagining Medicine

      By: Ramon Casadesus-Masanell, Claudio Feser, Karolin Frankenberger and David Redaschi
      This case unfolds around the first-ever approved personalized cancer treatment, how Novartis wrapped it into a new business model design, and how Novartis scaled it. Novartis — one of the largest pharmaceutical companies in the world — is, among other ventures,... View Details
      Keywords: Health Testing and Trials; Health Care and Treatment; Business Model; Problems and Challenges; Pharmaceutical Industry; Switzerland
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      Casadesus-Masanell, Ramon, Claudio Feser, Karolin Frankenberger, and David Redaschi. "Novartis (C): Reimagining Medicine." Harvard Business School Supplement 723-445, May 2023. (Revised June 2023.)
      • 2023
      • Working Paper

      Setting Gendered Expectations? Recruiter Outreach Bias in Online Tech Training Programs

      By: Jacqueline N. Lane, Karim R. Lakhani and Roberto Fernandez
      Competence development in digital technologies, analytics, and artificial intelligence is increasingly important to all types of organizations and their workforce. Universities and corporations are investing heavily in developing training programs, at all tenure... View Details
      Keywords: STEM; Selection and Staffing; Gender; Prejudice and Bias; Training; Equality and Inequality; Competency and Skills
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      Lane, Jacqueline N., Karim R. Lakhani, and Roberto Fernandez. "Setting Gendered Expectations? Recruiter Outreach Bias in Online Tech Training Programs." Harvard Business School Working Paper, No. 23-066, April 2023. (Accepted by Organization Science.)
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