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All HBS Web
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Science →
- Article
The Evolution of Science-Based Business: Innovating How We Innovate
By: Gary P. Pisano
Science has long been connected to innovation and to business. As early as the late 19th century, chemical companies, realizing the commercial potential of science, created the first industrial research laboratories. During much of the 20th century, large-scale...
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Keywords:
Entrepreneurship;
Governance;
Innovation and Management;
Risk Management;
Research and Development;
Science-Based Business;
Commercialization
Pisano, Gary P. "The Evolution of Science-Based Business: Innovating How We Innovate." Special Issue on Management Innovation—Essays in the Spirit of Alfred D. Chandler. Industrial and Corporate Change 19, no. 2 (April 2010): 465–482.
- 2010
- Chapter
The Peculiar Politics of American Disaster Policy: How Television Has Changed Federal Relief
By: David Moss
Particularly since the 1960s, the federal government has played a significant role in financing disaster losses in the United States. The federal government may thus be thought of as providing an implicit form of public disaster insurance. However, unlike many...
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- December 2009 (Revised May 2010)
- Case
Codevasf
By: David E. Bell, Marcos Fava Neves, Luciano Thome e Castro and Natalie Kindred
With many countries facing scarcity of freshwater and farmable land, Brazil decided to leverage its wealth of both resources to attract global agribusiness players to the historically poor Sao Francisco Valley (SFV) in the country's northeast. To do so, Brazil was...
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Keywords:
Agribusiness;
Resource Allocation;
Bids and Bidding;
Infrastructure;
Supply Chain;
Business and Government Relations;
Natural Environment;
Agriculture and Agribusiness Industry;
Brazil
Bell, David E., Marcos Fava Neves, Luciano Thome e Castro, and Natalie Kindred. "Codevasf." Harvard Business School Case 510-042, December 2009. (Revised May 2010.)
- 2009
- Chapter
Acting in Time Against Disasters: A Comprehensive Risk Management Framework
By: Herman B. Leonard and Arnold M. Howitt
Leonard, Herman B., and Arnold M. Howitt. "Acting in Time Against Disasters: A Comprehensive Risk Management Framework." Chap. 2 in Learning from Catastrophes: Strategies for Reaction and Response, edited by Howard Kunreuther and Michael Useem, 18–41. Wharton School Publishing, 2009.
- 2009
- Working Paper
Negotiating the Path of Abraham
By: Kimberlyn Leary, James K. Sebenius and Joshua Weiss
In the face of daunting barriers, the Abraham Path Initiative envisions uncovering and revitalizing a route of cultural tourism that follows the path of Abraham and his family some 4,000 years ago across the Middle East. It begins in the ancient ruins of Harran, in...
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Keywords:
Development Economics;
Social Entrepreneurship;
Negotiation;
Business and Community Relations;
Business and Government Relations;
Religion;
Environmental Sustainability;
Tourism Industry;
Middle East
Leary, Kimberlyn, James K. Sebenius, and Joshua Weiss. "Negotiating the Path of Abraham." Harvard Business School Working Paper, No. 10-049, December 2009.
- December 2009 (Revised April 2012)
- Case
Neoprene
By: Tom Nicholas and Felipe Tamega Fernandes
In 1931, during one of the worst economic crises in U.S. history, Du Pont announced the discovery of an innovative rubber synthetic product—neoprene. Yet at the time of the announcement, Du Pont did not have any neoprene to sell. Manufacturing facilities were still...
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Keywords:
Financial Crisis;
Business History;
Innovation and Invention;
Product Development;
Risk and Uncertainty;
Science-Based Business;
Commercialization;
Chemical Industry;
United States
Nicholas, Tom, and Felipe Tamega Fernandes. "Neoprene." Harvard Business School Case 810-084, December 2009. (Revised April 2012.)
- November 2009 (Revised December 2009)
- Case
GTC Biotherapeutics: Developing Medicines in the Milk of Goats
By: Ray A. Goldberg and Sarah Morton
GTC is the first company in the animal world to receive FDA approval of a transgenic pharmaceutical. What are the implications for other firms in plants and animals and their opportunities to produce new medicines in an economical and safe fashion?
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Keywords:
Health Care and Treatment;
Animal-Based Agribusiness;
Plant-Based Agribusiness;
Science-Based Business;
Medical Specialties;
Product;
Technological Innovation;
Health Industry;
Pharmaceutical Industry;
United States
Goldberg, Ray A., and Sarah Morton. "GTC Biotherapeutics: Developing Medicines in the Milk of Goats." Harvard Business School Case 910-403, November 2009. (Revised December 2009.)
- November 2009 (Revised April 2010)
- Case
Rose Smart Growth Investment Fund
By: Arthur I Segel and Justin Seth Ginsburgh
The Jonathan Rose Companies must decide how to design and launch an innovative new real estate fund focused on green and transit oriented properties. JRC seeks to show through the fund that smart growth and green buildings provide superior economic returns to sprawl...
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Keywords:
Property;
Buildings and Facilities;
Transition;
Financing and Loans;
Investment Funds;
Investment;
Marketing;
Energy Conservation;
Business Strategy;
Growth and Development Strategy;
Environmental Sustainability;
Finance;
Real Estate Industry
Segel, Arthur I., and Justin Seth Ginsburgh. "Rose Smart Growth Investment Fund." Harvard Business School Case 210-033, November 2009. (Revised April 2010.)
- November 2009
- Case
The Explosion of Genetic Testing: Opportunities and Challenges
By: Richard G. Hamermesh, Mara G. Aspinall and Rachel Gordon
This case study invites the reader to consider genetic testing in several different lights. First, can the business of genetic testing be considered a disruptive innovation to the current drug therapy model as defined by Harvard Business School Professor Clay...
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- November 2009 (Revised March 2010)
- Case
Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story
By: Richard G. Hamermesh, Raju Kucherlapati and Rachel Gordon
In May 2007, Amgen Inc. (Amgen) received disappointing news from the European Medicines Agency (EMEA) that its drug Vectibix, developed to fight metastatic colorectal cancer, had been rejected. This was especially surprising news given that a similar rival drug had...
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Keywords:
Entrepreneurship;
Governing Rules, Regulations, and Reforms;
Health Testing and Trials;
Marketing Strategy;
Product Positioning;
Genetics;
Biotechnology Industry;
Europe;
United States
Hamermesh, Richard G., Raju Kucherlapati, and Rachel Gordon. "Managing Drugs on the Forefront of Personalized Medicine: The Erbitux and Vectibix Story." Harvard Business School Case 810-066, November 2009. (Revised March 2010.)
- November 2009
- Article
Responding to Public and Private Politics: Corporate Disclosure of Climate Change Strategies
By: Erin Marie Reid and Michael W. Toffel
The challenges associated with climate change will require governments, citizens, and firms to work collaboratively to reduce greenhouse gas emissions, a task that requires information on companies' emissions levels, risks, and reduction opportunities. This paper...
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Keywords:
Climate Change;
Problems and Challenges;
Pollutants;
Risk and Uncertainty;
Business and Shareholder Relations;
Management Practices and Processes;
Social Issues;
Corporate Disclosure;
Values and Beliefs;
Governing Rules, Regulations, and Reforms;
Government and Politics
Reid, Erin Marie, and Michael W. Toffel. "Responding to Public and Private Politics: Corporate Disclosure of Climate Change Strategies." Strategic Management Journal 30, no. 11 (November 2009): 1157–1178. (Featured by the Network for Business Sustainability.)
- October 2009
- Case
Low-k Dielectrics at IBM
By: Willy C. Shih and Giovanni Carraro
Innovations at the frontiers of technology carry enormous risk of making wrong choices. This case examines a decision made by IBM in its semiconductor process technology strategy: a material to use as a dielectric insulator in its leading edge silicon chip technology....
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Keywords:
Competency and Skills;
Decision Choices and Conditions;
Technological Innovation;
Product Development;
Science;
Creativity;
Semiconductor Industry;
United States
Shih, Willy C., and Giovanni Carraro. "Low-k Dielectrics at IBM." Harvard Business School Case 610-023, October 2009.
- October 2009 (Revised January 2014)
- Teaching Note
Sustainability at Millipore (TN)
Teaching Note for [610012].
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- September 2009 (Revised September 2010)
- Case
Genzyme Center (A)
By: Michael W. Toffel and Aldo Sesia
Genzyme Corporation is in the midst of planning its new corporate headquarters, which incorporates many innovative green building features. After learning that the building as planned would likely earn a LEED Silver rating, an intermediate score in the LEED green...
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Keywords:
Green Building;
LEED Rating System;
Economic And Environmental Performance;
Program Evaluation And Assessment;
Tradeoffs Between Process- And Performance Standards;
Buildings and Facilities;
Business Headquarters;
Governing Rules, Regulations, and Reforms;
Standards;
Corporate Social Responsibility and Impact;
Performance Improvement;
Environmental Sustainability;
Pollutants;
Green Technology Industry
Toffel, Michael W., and Aldo Sesia. "Genzyme Center (A)." Harvard Business School Case 610-008, September 2009. (Revised September 2010.)
- September 2009 (Revised December 2009)
- Supplement
Genzyme Center (B)
By: Michael W. Toffel and Aldo Sesia
Genzyme Corporation is in the midst of planning its new corporate headquarters, which incorporates many innovative green building features. After learning that the building as planned would likely earn a LEED Silver rating, an intermediate score in the LEED green...
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Keywords:
Environmental Sustainability;
Corporate Social Responsibility and Impact;
Standards;
Cost vs Benefits;
Biotechnology Industry;
Construction Industry;
Real Estate Industry;
Green Technology Industry
Toffel, Michael W., and Aldo Sesia. "Genzyme Center (B)." Harvard Business School Supplement 610-009, September 2009. (Revised December 2009.)
- September 2009 (Revised December 2009)
- Supplement
Genzyme Center (C)
By: Michael W. Toffel and Aldo Sesia
Genzyme Corporation is in the midst of planning its new corporate headquarters, which incorporates many innovative green building features. After learning that the building as planned would likely earn a LEED Silver rating, an intermediate score in the LEED green...
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Keywords:
Environmental Sustainability;
Corporate Social Responsibility and Impact;
Standards;
Cost vs Benefits;
Biotechnology Industry;
Construction Industry;
Real Estate Industry;
Green Technology Industry
Toffel, Michael W., and Aldo Sesia. "Genzyme Center (C)." Harvard Business School Supplement 610-010, September 2009. (Revised December 2009.)
- September – October 2009
- Article
U.S. Energy Policy: Overcoming Barriers to Acting
By: Max Bazerman
Energy policy is on everyone's mind these days. The U.S. presidential campaign focused on energy independence and exploration (drill, baby, drill), climate change, alternative fuels, even nuclear energy. But there is a serious problem endemic to America's energy...
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Keywords:
Policy;
Climate Change;
Energy Sources;
Government and Politics;
Cognition and Thinking;
Management Analysis, Tools, and Techniques;
Problems and Challenges;
Non-Renewable Energy;
Economics;
Natural Environment;
Energy Industry;
United States
Bazerman, Max. "U.S. Energy Policy: Overcoming Barriers to Acting." Environment: Science and Policy for Sustainable Development (September–October 2009). (This is a adaptation of a paper that originally appeared as "Barriers to Acting in Time on Energy, and Strategies for Overcoming Them" in K. Gallagher (Ed.), Acting in Time on Energy Policy. Washington, DC: Brookings, 2009.)
- August 2009 (Revised August 2010)
- Case
Calera Corporation
By: Joseph B. Lassiter III, Thomas J. Steenburgh and Lauren Barley
Brent Constantz, founder, CEO, and president of Calera Corporation, felt a surge of optimism as he gazed at the recently commissioned prototype flue gas processing line at Calera's R&D facility in Moss Landing, California. It was late May 2009, and Calera was an...
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Keywords:
Business Startups;
Entrepreneurship;
Product Design;
Product Development;
Environmental Sustainability;
Commercialization;
Green Technology Industry
Lassiter, Joseph B., III, Thomas J. Steenburgh, and Lauren Barley. "Calera Corporation." Harvard Business School Case 810-030, August 2009. (Revised August 2010.)
- 2009
- Chapter
Self-regulatory Institutions for Solving Environmental Problems: Perspectives and Contributions from the Management Literature
By: Andrew A. King and Michael W. Toffel
Scholars of management have long considered how institutions can help resolve market imperfections and thereby improve human welfare. Most previous research has emphasized the use of for-profit firms. Such institutions cannot effectively address many environmental...
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Keywords:
For-Profit Firms;
Investment;
Governing Rules, Regulations, and Reforms;
Corporate Social Responsibility and Impact;
Environmental Sustainability;
Competitive Advantage
King, Andrew A., and Michael W. Toffel. "Self-regulatory Institutions for Solving Environmental Problems: Perspectives and Contributions from the Management Literature." Chap. 4 in Governance for the Environment: New Perspectives, edited by Magali Delmas and Oran Young, 98–115. Cambridge University Press, 2009.
- July 2009 (Revised January 2014)
- Case
Sustainability at Millipore
By: Michael W. Toffel and Katharine Lee
This case describes Millipore Corporation's approach to becoming a more environmentally sustainable company. As he prepared for his quarterly meeting with the CEO, the Director of Sustainability needed to develop positions on several issues. Tactically, he needed to...
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Keywords:
Investment;
Corporate Disclosure;
Operations;
Corporate Social Responsibility and Impact;
Organizational Structure;
Natural Environment;
Environmental Sustainability;
Pollutants
Toffel, Michael W., and Katharine Lee. "Sustainability at Millipore." Harvard Business School Case 610-012, July 2009. (Revised January 2014.) (defining sustainability in a corporate context, managing greenhouse gas (GHG) emissions including inventories, targets, disclosure, reduction strategies.)