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  • All HBS Web  (4,740)
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  • October 2007 (Revised July 2013)
  • Case

Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech

By: Robert F. Higgins, Sophie LaMontagne and Brent Kazan
In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates into development. However, several questions related to... View Details
Keywords: Philanthropy; Philanthropy Funding; Innovation; Funding Model; Venture Capital; Partners and Partnerships; Financing and Loans; Investment Funds; Acquisition; Philanthropy and Charitable Giving; Biotechnology Industry; Pharmaceutical Industry; San Diego
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Higgins, Robert F., Sophie LaMontagne, and Brent Kazan. "Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech." Harvard Business School Case 808-005, October 2007. (Revised July 2013.)
  • 2011
  • Working Paper

What Do Development Banks Do? Evidence from Brazil, 2002-2009

By: Sergio G. Lazzarini, Aldo Musacchio, Rodrigo Bandeira-de-Mello and Rosilene Marcon
While some authors view development banks as an important tool to alleviate capital constraints in scarce credit markets and unlock productive investments, others see those banks as conduits of cheap loans to politically connected firms that could obtain capital... View Details
Keywords: Cost of Capital; Credit; Equity; Banks and Banking; Financing and Loans; Investment; Government and Politics; Data and Data Sets; Resource Allocation; Markets; Performance; Banking Industry; Brazil
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Lazzarini, Sergio G., Aldo Musacchio, Rodrigo Bandeira-de-Mello, and Rosilene Marcon. "What Do Development Banks Do? Evidence from Brazil, 2002-2009." Harvard Business School Working Paper, No. 12-047, December 2011.
  • 28 Feb 2011
  • Research & Ideas

The Importance of ‘Don’t’ in Inducing Ethical Employee Behavior

In trying to encourage good moral conduct, it's common for a company to come up with a list of don'ts—wording policies such that they focus on unethical behavior employees should avoid rather than on ethical acts they should strive to... View Details
Keywords: by Carmen Nobel

    Dwight B. Crane

    Mr. Crane was a member of the Finance Faculty at Harvard Business School for a number of years, working primarily in the field of financial institutions and corporate governance. He taught in the MBA and executive education programs at the School, most recently... View Details

    • 23 Jun 2014
    • Research & Ideas

    In Venture Capital, Birds of a Feather Lose Money Together

    few key questions: What specific characteristics influence individuals' desire to work together on an investment deal? And given that influence, how does affinity affect investment performance? Do common... View Details
    Keywords: by Carmen Nobel; Financial Services

      Das Narayandas

      Das Narayandas is the Edsel Bryant Ford Professor of Business Administration at the Harvard Business School. His academic credentials include a Bachelor of Technology degree in Engineering from the Indian Institute of Technology, Bombay (IITB), a Post-Graduate... View Details

      Keywords: industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods; industrial goods
      • 19 Mar 2019
      • First Look

      New Research and Ideas, March 19, 2019

      inequality affects behaviour towards the rich and poor. In Experiment 1, participants who became aware that wealthy individuals donated a smaller percentage of their income switched from rewarding the wealthy to rewarding the poor. In Experiments 2 and 3, participants... View Details
      Keywords: Dina Gerdeman
      • December 2005 (Revised November 2006)
      • Case

      Corning, 2002

      By: Malcolm P. Baker and James Quinn
      Corning, with large investments in fiber optic technology, was hit particularly hard by the collapse of the telecommunications industry in 2001. With over $4 billion in debt, the firm's survival appears to rest on raising additional equity capital. The protagonist is... View Details
      Keywords: Financial Strategy; Financial Condition; Financial Instruments; Valuation; Capital; Public Equity; Stock Shares; Business or Company Management; Strategy; Manufacturing Industry; Industrial Products Industry
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      Baker, Malcolm P., and James Quinn. "Corning, 2002." Harvard Business School Case 206-018, December 2005. (Revised November 2006.)

        Srikant M. Datar

        Srikant M. Datar became the eleventh dean of Harvard Business School on 1 January 2021. During his tenure as a faculty member, he served as Senior Associate Dean for University Affairs (including Faculty Chair of the Harvard Innovation Lab), for Research, for... View Details

        Keywords: investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry
        • April 2025
        • Case

        Breezm: Innovative 3D-Printed Eyewear (A)

        By: Juan Alcácer, Brian Mao Fu and Adina Wong
        In 2023, Breezm, a South Korean startup, faced a strategic decision about how to grow its innovative 3D-printed, custom-fit eyewear business. Co-founded in 2017 by Zenma Park and Wooseok Sung, Breezm combined facial scanning, AI, and in-house production to solve the... View Details
        Keywords: 3D Printing; Eyeyewear; Growth; Business Startups; AI and Machine Learning; Technological Innovation; Growth and Development Strategy; Risk and Uncertainty; Expansion; South Korea
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        Alcácer, Juan, Brian Mao Fu, and Adina Wong. "Breezm: Innovative 3D-Printed Eyewear (A)." Harvard Business School Case 725-376, April 2025.
        • January 2025 (Revised April 2025)
        • Case

        Mercado Libre: The Best Is Yet to Come

        By: Krishna G. Palepu, Fernando Fragueiro, Carla Larangeira and Mariana Cal
        In 2024, Marcos Galperín, CEO and co-founder of Mercado Libre, reflected on its 25-year rise as Latin America’s largest marketplace, fintech leader, and most valuable public company. With operations spanning 18 countries and a robust ecosystem combining e-commerce,... View Details
        Keywords: Entrepreneurship; Multinational Firms and Management; Recruitment; Compensation and Benefits; Innovation Leadership; Innovation Strategy; Leadership Style; Business or Company Management; Management Practices and Processes; Management Succession; E-commerce; Emerging Markets; Distribution; Logistics; Organizational Culture; Organizational Design; Business Strategy; Competition; Growth and Development Strategy; Corporate Strategy; Technology Industry; Financial Services Industry; Retail Industry; Latin America; Mexico; Brazil; Argentina
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        Palepu, Krishna G., Fernando Fragueiro, Carla Larangeira, and Mariana Cal. "Mercado Libre: The Best Is Yet to Come." Harvard Business School Case 325-065, January 2025. (Revised April 2025.)
        • November 2023
        • Supplement

        'Care in Every Drop': Ayala Corporation and Manila Water (B)

        By: Debora L. Spar, Paul Healy, Tricia Peralta and Julia Comeau
        Since 1834, eight generations of the Ayala family have used their conglomerate to fund nation-building projects in the Philippines, including investments in tramcars, telecommunications, hospitals, and schools. In 1997, Ayala’s subsidiary, Manila Water, took control of... View Details
        Keywords: Family Business; Economic Growth; Social Entrepreneurship; Climate Change; Natural Resources; Crisis Management; Failure; Privatization; Social Issues; Urban Development; Adaptation; Infrastructure; Utilities Industry; Philippines
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        Spar, Debora L., Paul Healy, Tricia Peralta, and Julia Comeau. "'Care in Every Drop': Ayala Corporation and Manila Water (B)." Harvard Business School Supplement 324-039, November 2023.
        • 06 Sep 2005
        • What Do You Think?

        What are the Lessons of New Orleans?

        Summing Up Management is a complex process. Good plans executed poorly may be worse than poor plans executed well. This is never truer than at times of disaster, in which plans made from afar have to be implemented by those on the scene... View Details
        Keywords: by James Heskett
        • 24 Sep 2014
        • Op-Ed

        Stop Thinking of Climate Change as a Religious or Political Issue

        ideologies at the door and approached the topic as we do any other topic involving investment under uncertainty. OP-ED COLLECTION The Business of Climate Change What role should business leaders play in trying to affect climate change?... View Details
        Keywords: by Forest Reinhardt; Energy; Utilities
        • 04 Aug 2009
        • First Look

        First Look: August 4

        "going public" and "going private'" transactions. We then find that majority PE-backed private firms engage in less book-tax nonconforming tax planning than public years; nonetheless, they exhibit substantially lower... View Details
        Keywords: Martha Lagace

          Ray A. Goldberg

          A native of North Dakota, Dr. Goldberg received his A.B. from Harvard University in 1948, his MBA from the Harvard Graduate School of Business Administration in 1950 and his Ph.D. in Agricultural Economics from the University of Minnesota in 1952.

          ... View Details

          Keywords: agribusiness; agriculture; fast food; food; food processing; forest products; grocery; high technology; information; restaurant; retailing; soft drink; textiles; tobacco; transportation; wholesale; wine

            Robert C. Merton

            Robert C. Merton is the School of Management Distinguished Professor of Finance at the MIT Sloan School of Management.

            Merton is University Professor Emeritus at Harvard University and was the George Fisher Baker Professor of... View Details

            Keywords: investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry; investment banking industry
            • 18 Jun 2024
            • Cold Call Podcast

            How Natural Winemaker Frank Cornelissen Innovated While Staying True to His Brand

            Keywords: Re: Tiona W. Zuzul; Food & Beverage; Agriculture & Agribusiness
            • March 2025
            • Supplement

            Intuition Robotics: An AI Companion for Older Adults (B)

            By: Amit Goldenberg, Elie Ofek and Orna Dan
            Two years after Intuition Robotics opted to pursue a business-to-government contract with the New York State Office of the Aging, and put direct-to-consumer efforts on the back burner, it was at a crossroads. The partnership had been successful, and the company had... View Details
            Keywords: Business Model; AI and Machine Learning; Resource Allocation; Business and Government Relations; Partners and Partnerships; Business Strategy; Health Industry; Technology Industry; New York (state, US); United States
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            Goldenberg, Amit, Elie Ofek, and Orna Dan. "Intuition Robotics: An AI Companion for Older Adults (B)." Harvard Business School Supplement 925-019, March 2025.
            • July 2018 (Revised September 2018)
            • Case

            Donald Trump and the Tax Cuts and Jobs Act

            By: Matthew Weinzierl and Robert Scherf
            In January 2018, President Donald Trump was full of optimism. He had just signed the most substantial legislation of his young presidency, the Tax Cuts and Jobs Act (TCJA), making major changes to the tax code. Echoing his campaign slogan—Make America Great Again—Trump... View Details
            Keywords: Taxation; Jobs and Positions; Government and Politics; Public Opinion; United States
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            Weinzierl, Matthew, and Robert Scherf. "Donald Trump and the Tax Cuts and Jobs Act." Harvard Business School Case 719-002, July 2018. (Revised September 2018.)
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