Publications

15 Feb 2017
Op-Ed

What Africa Can Teach the United States About Funding Infrastructure Projects

investors, and builders can learn from the African experience, where public-private partnerships and deployments of new technologies are illuminating new ways to approach the task of funding infrastructure despite a scarcity of government... View Details

Keywords: by John Macomber; Construction

24 Sep 2007
Research & Ideas

The FDA: What Will the Next 100 Years Bring?

but not impede innovations targeted to specific subgroups. Q: What are you working on next? A: I recently joined the Business, Government & International Economy unit at HBS and am in the early stages of... View Details

Keywords: by Sean Silverthorne; Biotechnology; Consumer Products; Food & Beverage; Health

25 May 2016
Research & Ideas

How Consumers and Businesses are Reshaping Public Health

be headquartered in England in order to achieve a lower corporate tax rate. The British government favored the merger as it would boost the high-priority life sciences sector, but little attention was paid to whether the integration of... View Details

Keywords: by John A. Quelch; Health

2024
Working Paper

Prozac—Controversial Blockbuster: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes the development of Prozac, a blockbuster drug that transformed the treatment of depression – and became a cultural phenomenon in the United States. Specifically, we chronicle the: 1) prior treatments for depression and the research that... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

24 Sep 2001
Research & Ideas

Five Questions for Debora L. Spar

innovation work? A: There are many. Recent decisions against Napster and other file-sharing firms, for example, confirm that property means are by no means dead online. On the contrary, both citizens and firms want to preserve property... View Details

Keywords: by Sean Silverthorne

2024
Working Paper

Coronary Artery Bypass Grafting—Impossible to Routine: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Fabio Villa

We describe how Coronary Artery Bypass Grafting (CABG, or more popularly, “bypass”) operations revolutionized the treatment of coronary disease (that can produce fatal heart attacks and debilitating angina). Specifically, we chronicle the: 1) development of the... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

This case history describes the development of three generations of cephalosporins – antibiotics that have significantly reduced hospital infections. Specifically, we chronicle how: 1) Early (pre-cephalosporin) antibiotics were developed in the first half of the 20th... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins

We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances

By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar

We describe how operations through laparoscopes – tubular instruments inserted into abdominal cavities – revolutionized gynecological and other surgeries inside the abdomen, such as gall bladder removal. Specifically, we chronicle the 1) foundational contributions of... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Computed Tomography (CT)--Beyond Traditional X-Rays: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how Computed Tomography (CT) scanners - that combine Xrays and computers to image soft tissues of the brain and other organs -- have become a widely used diagnostic tool. Specifically, we chronicle the 1) initial development of CT... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

01 Feb 2012
What Do You Think?

Is Support for Small Business Misplaced?

investments in research and development, was emphasized by several respondents. Mark Hopkinson remarked that "most big companies rely for their tech pipeline of new products on the innovation that comes from small business, acquiring... View Details

Keywords: by James Heskett

23 Jul 2024
In Practice

The New Rules of Trade with China: Navigating Tariffs, Turmoil, and Opportunities

economy. Over the last decade, we have seen the Chinese Communist Party’s (CCP) involvement in corporate governance grow significantly as a shareholder and through political and legal interventions.While it is not correct at all to assume... View Details

Keywords: by Rachel Layne; Manufacturing; Retail; Fashion; Industrial Products; Consumer Products; Steel; Transportation; Telecommunications

05 Aug 2002
Research & Ideas

Five questions for Regina E. Herzlinger

needs; risk-adjustment of payment will make the sick much more attractive enrollees than the present uniform pricing system. All boats rise in a rising sea. Other consumer-driven markets demonstrate that suppliers innovate to reach all... View Details

Keywords: by Martha Lagace

26 Oct 2017
Research Event

In an Era of 'Fake News,' What is the Future of Advertising and Publishing?

White House popularized the term “fake news,” the influence of social media advertising and online publishing requires serious reexamination. That began to happen October 24 at the The Future of Advertising and Publishing conference held at the Harvard View Details

Keywords: by Jen Deaderick; Media & Broadcasting; Journalism & News

21 Jul 2006
Op-Ed

Enron Jury Sent the Right Message

behavior could possibly arise, lie many examples of highly innovative management: the successful intermediation of the natural gas market, the "gas bank" created by Jeff Skilling, the development of standardized commodity... View Details

Keywords: by Malcolm S. Salter

2024
Working Paper

HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms