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  • July 2013 (Revised November 2021)
  • Module Note

Exploration vs. Exploitation

By: Willy Shih
This module note introduces James March's concept of exploration and exploitation, and the management challenge of balancing the allocation of resources to the two activities in the firm. The note also touches on the O'Reilly and Tushman paper on the ambidextrous... View Details
Keywords: Exploration And Exploitation; Exploitation; Research; Scientific Research; Product Commercialization; Innovation and Invention; Innovation and Management; Innovation Leadership; Innovation Strategy; Technological Innovation; Knowledge Acquisition; Growth and Development Strategy; Resource Allocation; Strategic Planning; Research and Development; Science-Based Business; Corporate Strategy; Knowledge Sharing; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; United States
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  • 29 Jan 2013
  • First Look

First Look: Jan. 29

facing the scientific founder and CEO of a promising, early stage bio-pharmaceuticals company. Should the company establish a proposed alliance with a pharmaceutical firm? Should it create a nutraceuticals business in parallel to its... View Details
Keywords: Sean Silverthorne
  • 10 Sep 2007
  • Research & Ideas

High Note: Managing the Medici String Quartet

The panel consisted of Bob Frosch, who used to head NASA and R&D for GM; Vicki Sato, who was president of Vertex Pharmaceuticals and is now on the HBS faculty; and Peter Hanke, a conductor. These people have had a lot of experience... View Details
Keywords: by Martha Lagace; Music
  • 2016
  • Book

Consumers, Corporations, and Public Health: A Case-Based Approach to Sustainable Business

By: John A. Quelch
The public health footprint associated with corporate behavior has come under increased scrutiny in the last decade, with an increased expectation that private profit not come at the expense of consumer welfare.

Consumers, Corporations, and Public... View Details
Keywords: Consumer; Corporate Culture; Public Health; Consumer Behavior; Marketing Strategy; Corporate Strategy; Health; Innovation and Invention; Innovation and Management; Supply Chain Management; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Asia; Oceania; North and Central America; Middle East; Latin America; Europe
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  • September 2024
  • Case

Myeloma Investment Fund

By: Kyle Myers and Scott Sawaya
This case explores a critical decision facing the Myeloma Investment Fund (MIF) as it evaluates two investment opportunities aimed at accelerating a cure for multiple myeloma.

The MIF, a venture philanthropy fund, must choose between two distinct paths. One... View Details
Keywords: Venture Philanthropy; Biomedical Research; Investing For Impact; Innovation ＆ Entrepreneurship; Venture Capital; Science-Based Business; Philanthropy and Charitable Giving; Decision Making; Health Care and Treatment; Pharmaceutical Industry; Pharmaceutical Industry
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  • February 2015 (Revised November 2015)
  • Supplement

Building an Integrated Biopharma Company: Crucell (B)

By: Richard G. Hamermesh, Marianne Van Der Steen and Susan Harmeling
The Crucell (B) case updates events at Crucell since 2009. In September, 2009, Johnson & Johnson acquired 18% of Crucell for $400 million. This investment was part of a business development deal. Subsequently, in 2012, Johnson & Johnson acquired Crucell for $2.8... View Details
Keywords: Biotechnology; Biopharmacy Company; Licensing Agreements In Biopharmacy; Licensing; Human Cell-line Technology; Vaccine; Healthcare Innovation; Global Health; Entrepreneurship; Health Care and Treatment; Acquisition; Innovation and Invention; Pharmaceutical Industry; Pharmaceutical Industry
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  • July 2014
  • Teaching Note

Vaxess Technologies, Inc.

By: John A. Quelch
Keywords: Marketing Innovations; Entrepreneurship; Innovation and Management; Business Startups; Marketing Strategy; Pharmaceutical Industry; Pharmaceutical Industry; North and Central America
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  • June 2013
  • Supplement

Can PACIV (Puerto Rico) Serve European Customers? (Video Supplement)

By: Jim Sharpe
This is Video Supplement for Can PACIV (Puerto Rico) Serve European Customers? HBS Case #808099. View Details
Keywords: Entrepreneurial Management; Global Organizations; Service; Hiring; Incentives, Motivation; Joint Ventures; Customer Service Excellence; Customer Relationship Management; Empowerment; International Expansion; Ownership Structure; Culture; Organization Alignment; Growth and Development Strategy; Entrepreneurship; Private Ownership; Globalized Markets and Industries; Globalized Firms and Management; Pharmaceutical Industry; Pharmaceutical Industry; Puerto Rico; United Kingdom
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  • May 2013
  • Supplement

Can PACIV (Puerto Rico) Serve European Customers?

This is the Spreadsheet Supplement HBS Case #808099 (PACIV). Includes Exhibit 1a, Exhibit 1b, Exhibit 1c, Exhibit 1d, Exhibit 1e, Exhibit 1f, Exhibit 5, Exhibit 6, and Exhibit 8. View Details
Keywords: Entrepreneurs; Foreign Subsidiaries; Global Business; International Business; International Entrepreneurial Finance; International Operations; Entrepreneurship; Globalization; International Finance; Operations; Finance; Pharmaceutical Industry; Pharmaceutical Industry; Puerto Rico; United Kingdom; Europe; United States
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  • November 2011 (Revised February 2012)
  • Case

China Novartis Institute for Biomedical Research: Building a Sustainable, Globally Integrated Research Enterprise

By: Vicki Sato, Christoph Jaeker and Pooja Mehta Solanki
As the head of the Novartis Institute for Biomedical Research in China, En Li was shepherding a $1 billion R&D investment in China. So far he had been able to attract a large number of Chinese-born but US-trained scientists to play a critical role in establishing the... View Details
Keywords: Globalized Firms and Management; Research; Corporate Strategy; Pharmaceutical Industry; Pharmaceutical Industry; China
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  • April 2010
  • Teaching Note

Wyeth Pharmaceuticals: Spurring Scientific Creativity with Metrics

By: Robert S. Huckman
Teaching Note for [607008]. View Details
Keywords: Restructuring; Decisions; Innovation and Invention; Research and Development; Pharmaceutical Industry; Pharmaceutical Industry
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  • October 2009 (Revised July 2013)
  • Case

Gilead Sciences, Inc.: Access Program

By: V. Kasturi Rangan and Katharine Lee
Gilead Sciences, the U.S. leader in HIV/AIDS medicines, with global sales of $5.4 billion in 2009, had undertaken several innovative actions to make its anti-viral products available to over 100 low- and middle-income countries. Having reached nearly 680,000 patients... View Details
Keywords: Health Care and Treatment; Emerging Markets; Product; Sales; Competitive Strategy; Pharmaceutical Industry; Pharmaceutical Industry
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  • March 2009
  • Teaching Note

Proteus Biomedical: Making Pigs Fly (TN)

By: Richard G. Hamermesh
Teaching Note for [809051]. View Details
Keywords: Business Startups; Information Technology; Competition; Negotiation Deal; Pharmaceutical Industry; Pharmaceutical Industry
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  • June 2003 (Revised October 2004)
  • Case

Novartis: The Challenge of Success (D)

By: Sandra J. Sucher and Stacy McManus
Supplements the (A) and (B) cases. View Details
Keywords: Pharmaceutical Industry; Pharmaceutical Industry
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  • June 1999 (Revised June 2000)
  • Case

Eckerd Corporation

By: Michael E. Porter and John E. Kelleher
Describes the history and current situation in the retail pharmacy industry, including competition from new merchants and Internet drugstores. Eckerd, one of the top four drug chains, must decide how to position itself for the future. View Details
Keywords: Competition; Alignment; Supply and Industry; Pharmaceutical Industry; Pharmaceutical Industry
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  • 30 Oct 2007
  • First Look

First Look: October 30, 2007

Changing Context of Pharmaceutical Risk Mitigation Author:Arthur A. Daemmrich Periodical:Pharmacy in History 49, no. 2 (2007): 61-75 Abstract In the wake of Vioxx, Avandia, and other recent prominent cases of drugs found to cause side... View Details
Keywords: Sean Silverthorne
  • 18 Aug 2017
  • Op-Ed

Op-Ed: Courageous Leader Triggers a Moral Revolt of CEOs Against Trump

actions was not without risk for the CEOs and their companies” While many CEOs prefer to stay under the radar and avoid public scrutiny, Ken Frazier led the way with his example. As the chair of PhRMA, the pharmaceutical manufacturers... View Details
Keywords: by Bill George
  • 20 May 2013
  • Op-Ed

Making America an Industrial Powerhouse Again

talent pool in the US biomedical field that is second to none. And the only way to get that talent is for companies-both domestic and foreign-to do their R&D here. That's why pharmaceutical and biotechnology companies from around the... View Details
Keywords: by Gary Pisano; Manufacturing
  • May 25, 2016
  • Comment

How Consumers and Businesses are Reshaping Public Health

By: John A. Quelch
Healthcare and education are two issues in which citizens around the world, rich and poor, are passionately interested. It has long been appreciated that the way that a society treats its youngest and oldest members says much about its moral maturity. Economic... View Details
Keywords: Healthcare; Consumer Power; Innovation In Healthcare Delivery; Mobile Healthcare; Transition; Transformation; Trends; Customer Satisfaction; Customer Value and Value Chain; Health Care and Treatment; Information; Collaborative Innovation and Invention; Independent Innovation and Invention; Innovation and Management; Innovation Leadership; Management; Marketing; Markets; Planning; Problems and Challenges; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; Pharmaceutical Industry; South America; North and Central America; Middle East; Europe; Asia
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  • 05 Mar 2001
  • What Do You Think?

Fine Coupling: Can Human Resource Management Learn from Supply Chain Management?

Productivity will improve as the alternation of job assignments eliminates the 'indispensable' worker." Connie Luthy says, "I have practiced 'Just-In-Time' hiring ... in the pharmaceutical industry.... I have advised my client... View Details
Keywords: by James Heskett

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