Publications

July 2002
Article

Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery

By: Stefan Thomke and Walter Kuemmerle

Keywords: Assets; Information Technology; Change; Health

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2020
Working Paper

Aggregate and Firm-Level Stock Returns During Pandemics, in Real Time

By: Laura Alfaro, Anusha Chari, Andrew Greenland and Peter K. Schott

We show that unexpected changes in the trajectory of COVID-19 infections predict U.S. stock returns, in real time. Parameter estimates indicate that an unanticipated doubling (halving) of projected infections forecasts next-day decreases (increases) in aggregate U.S.... View Details

Keywords: COVID-19; Stock Returns; Health Pandemics; Stocks; Investment Return; Forecasting and Prediction

September–October 2020
Article

The Past, Present, and (Near) Future of Gene Therapy and Gene Editing

By: Julia Pian, Amitabh Chandra and Ariel Dora Stern

Emerging gene therapy and gene-editing technologies will have a growing impact on patient lives and health-care delivery. We analyzed a decade of data on clinical trials and venture capital investments to understand the likely trajectory of genetically focused... View Details

Keywords: Gene Therapy; Gene Editing; Impact; Health Care and Treatment; Technological Innovation; Health Testing and Trials; Venture Capital; Change

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Web

Work & Life - Race, Gender & Equity

at home [1] 51 Women with children under 18 at home 54 Men with no children at home 54 Men with children under 18 at home Top 5 Industries Hours/Week Women Men Consulting / Professional Services 52 55 Educational Services / Academics 49 53 View Details

February 2002 (Revised May 2004)
Case

U.S. Labs

By: Michael J. Roberts and Robert F. Higgins

Describes the evolution of a start-up venture in the pathology lab segment of the clinical lab business. U.S. Labs tries a series of business models before running out of cash. The company is in dire need of financing, as its venture capital backers are refusing to put... View Details

Keywords: Entrepreneurship; Business Startups; Venture Capital; Financial Strategy; Financing and Loans; Business Model; Business or Company Management; Planning; Business Strategy; Health Industry

01 Sep 2013
News

A Focus on You

alumni—some well-known and others not so familiar—who are doing important work in, say, education, or health care, or entrepreneurial ventures. With this edition, we've given the "focus" concept a spin: We're looking at the alumni... View Details

Keywords: Colleges, Universities, and Professional Schools; Educational Services; Publishing Industries (except Internet); Information; News, Library, Internet, and Other Services; Information

30 Apr 2001
What Do You Think?

Dot.Com Shakeout: Chess or Roulette?

was that of T. N. Rao: "There is an immense business opportunity now for all the investing companies to pick up some very good dot.coms that have very sound business models. It is just that the principles of assessing the health of... View Details

Keywords: by James Heskett

Web

Investment Strategies - Course Catalog

already public acquirer - remains a critical step in corporate transformation by private equity investors and innovation by venture capitalists. Because public capital markets play such a key role in the global economy, government regulators and policy makers... View Details

26 Sep 2016
News

Steward gets $1.25b to fund expansion, repay Cerberus

January 1990 (Revised March 1991)
Case

American Red Cross Blood Services: Northeast Region

By: Robert L. Simons

Recounts the financial difficulties and management changes experienced by American Red Cross Blood Services: Northeast Region (NER) during the 1980s. After summarizing industry-wide changes in the collection, testing, and distribution of blood and blood products, the... View Details

Keywords: Change Management; Budgets and Budgeting; Financial Management; Restructuring; Health; SWOT Analysis; Social Enterprise; Marketplace Matching; Management Style; Organizational Culture; Organizational Change and Adaptation; Health Industry; Health Industry; North and Central America

Web

Blog | Social Enterprise | Harvard Business School

Impact Measurement Inclusive Finance International Development K-12 Education Leadership Fellows Leadership in Challenging Times MBA Programs Microfinance Non Profit Management Nonprofit Supportive Services Public Sector Public-Private... View Details

January 2007 (Revised December 2007)
Case

PSI: Social Marketing Clean Water

By: V. Kasturi Rangan, Nava Ashraf and Marie Bell

Senior management at PSI, arguably the world's largest and most successful social marketer with impressive achievements in the field of family planning, HIV/AIDS, and malaria prevention must determine what to do about their slow-to-take-off clean water initiative.... View Details

Keywords: Investment Funds; Health Care and Treatment; Social Marketing; Natural Environment; Social Enterprise; Business Strategy

August 2025
Article

Revenue Collapses and the Consumption of Small Business Owners in the COVID-19 Pandemic

By: Olivia S. Kim, Jonathan A. Parker and Antoinette Schoar

Using financial account data linking small businesses to their owner households, we examine how business owners’ consumption responded to changes in business revenues during the COVID-19 crisis. In the first two months following the National Emergency, business... View Details

Keywords: Revenue; Small Business; Health Pandemics; Spending; Consumer Behavior

Profile

Micah Macfarlane

Micah Macfarlane tries to make every career decision to make the greatest difference in the most lives. Before HBS, Micah worked in global health – expanding access to quality care and, especially, affordable medicines. "I worked to... View Details

Keywords: Healthcare/Biotech; Manufacturing/Energy; Nonprofit/Government/Education

March 2024 (Revised July 2024)
Case

AMC: The Zero Revenue Case

By: C. Fritz Foley and Donal O'Cofaigh

The onset of the Covid-19 pandemic put theatre company AMC’s already perilous financial situation under even further strain. The company’s high levels of debt resulted in a monthly cash-burn which left it facing an imminent Chapter-11 filing in the absence of... View Details

Keywords: Ethics; Insolvency and Bankruptcy; Public Equity; Stock Shares; Health Pandemics; Entertainment and Recreation Industry

Portrait Project

Josh Latson

started my life trying to be memorable for who I would become. I thought if I "made it out," moved away from Medford, MA, the blue-collar city where I grew up, to Yale and then a finance job that paid me well, then maybe, I... View Details

22 Feb 2022
News

An Rx for Small Business Recovery

suppliers—run with thin margins and minimal cash reserves, even in the best of times. “When COVID-19 hit, they felt the shock immediately,” Mills explains. Beginning in March 2020, the pandemic and unprecedented public health measures... View Details

Keywords: Deborah Blagg

February 2006 (Revised February 2009)
Case

AIDS in Brazil

By: Rohit Deshpande and Ricardo Reisen de Pinho

Abbott Labs has reached an impasse with the Brazilian government in negotiations over the pricing of a new anti-AIDS drug, Kaletra. The Brazilian government threatens compulsory licensing unless Abbott drastically reduces the price of Kaletra. View Details

Keywords: Price; Government and Politics; Health Care and Treatment; Health Disorders; Rights; Negotiation; Business and Government Relations; Pharmaceutical Industry; Brazil