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  • 2024
  • Working Paper

Cephalosporins—Fighting Hospital Infections: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins
This case history describes the development of three generations of cephalosporins – antibiotics that have significantly reduced hospital infections. Specifically, we chronicle how: 1) Early (pre-cephalosporin) antibiotics were developed in the first half of the 20th... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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  • 2024
  • Working Paper

Tamoxifen—Reducing Breast Cancer Risks: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant Datar and Katherine Stebbins
We describe the development of tamoxifen, considered a “gold standard” treatment for millions of breast cancer patients. Specifically, we describe breast cancer treatments before tamoxifen’s development; the initial development of tamoxifen from 1960 to 1973;... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation and Invention; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Governing Rules, Regulations, and Reforms
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  • 2024
  • Working Paper

Laparoscopy—Minimally Invasive Surgery: Case Histories of Transformational Advances

By: Amar Bhidé, Caitlin N. Bowler and Srikant M. Datar
We describe how operations through laparoscopes – tubular instruments inserted into abdominal cavities – revolutionized gynecological and other surgeries inside the abdomen, such as gall bladder removal. Specifically, we chronicle the 1) foundational contributions of... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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  • 26 Nov 2001
  • Research & Ideas

Women Entrepreneurs Use Springboard for Funding

What do a health food manufacturer, an infectious-diseases specialist and a content-management expert have in common? Answer: All are women, all are entrepreneurs. And by virtue of being women and entrepreneurs they share one... View Details
Keywords: by Martha Lagace
  • 19 Jan 2021
  • In Practice

Leadership Advice for Biden: Restore a Sense of Calm

the world into a multidimensional crisis. We are not only facing a health crisis, but economic and social crises, too, characterized by rising inequalities on top of an environmental crisis. A common root of these multiple crises can be... View Details
Keywords: by Dina Gerdeman
  • 15 Feb 2017
  • Op-Ed

What Africa Can Teach the United States About Funding Infrastructure Projects

investors, and builders can learn from the African experience, where public-private partnerships and deployments of new technologies are illuminating new ways to approach the task of funding infrastructure despite a scarcity of government... View Details
Keywords: by John Macomber; Construction
  • 11 Mar 2008
  • First Look

First Look: March 11, 2008

http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=808104 Partners in Health: The PACT Project Harvard Business School Case 608-065 Partners in Health (PIH) is a Boston-based, not-for-profit that provides View Details
Keywords: Martha Lagace
  • 01 Oct 2018
  • Working Paper Summaries

Negative Shocks and Innovation: Evidence from Medical Device Recalls

Keywords: by George P. Ball, Jeffrey T. Macher, and Ariel Dora Stern; Health; Health
  • June 2024
  • Case

SnapTravel: Betting on 'Super.com'

By: Reza Satchu and Tom Quinn
This case explores SnapTravel, a travel startup offering discounted hotel rooms, and its founders’ desire to pivot to a “super app” that saved customers money across many different purchase types. During the COVID-19 pandemic, Hussein Fazal and Henry Shi saw SnapTravel... View Details
Keywords: Business Growth and Maturation; Business Plan; Business Startups; Change Management; Disruption; Transformation; Volatility; Customer Focus and Relationships; Customer Value and Value Chain; Decisions; Income; Entrepreneurship; Geographic Scope; Cross-Cultural and Cross-Border Issues; Health Pandemics; Surveys; Knowledge Acquisition; Knowledge Use and Leverage; Leading Change; Crisis Management; Goals and Objectives; Risk Management; Consumer Behavior; Game Theory; Risk and Uncertainty; Adaptation; Diversification; Expansion; System Shocks; Technology Industry; Technology Industry; Canada; United States; Las Vegas
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  • 21 Apr 2020
  • Research & Ideas

7 Successful Battle Strategies to Beat COVID-19

teams in territory that models cannot predict. COVID-19 events deliver surprises daily to many organizations, from health care specialists to government officials. The decision-making process that responds to rapid change is once again as... View Details
Keywords: by Euvin Naidoo
  • 09 Jun 2015
  • First Look

First Look: June 9, 2015

third-party developers who would create an array of health-focused apps. Healthcare had long lagged behind other industries in adoption of technology as well as patient-relationship management. However, many View Details
Keywords: Sean Silverthorne
  • 12 Dec 2006
  • First Look

First Look: December 12, 2006

Diversity in the Workplace Harvard Business School Case 407-029 Purchase this case: http://www.hbsp.harvard.edu/b01/en/common/item_detail.jhtml?id=407029 Information Technology and Innovation at Shinsei Bank Harvard Business School Case... View Details
Keywords: Martha Lagace
  • 24 Mar 2002
  • Research & Ideas

Are Assets Only for America’s Wealthy?

enough money to prosper, low-income families' access to health benefits, their civic participation, family stability, and mental wellbeing are all diminished by their low success rate in building assets. Peter Tufano, Sylvan C. Coleman... View Details
Keywords: by Carla Tishler
  • 01 May 2020
  • In Practice

COVID-19’s Hard Lessons Might Prepare Business for Climate Change

Environmental Management in the Technology and Operations Management Unit, and Faculty Chair of the HBS Business and Environment Initiative. Rebecca Henderson: Short-term fears might guide decision-making   In the short run, COVID-19... View Details
Keywords: by Danielle Kost
  • 12 Oct 1999
  • Research & Ideas

Porter’s Perspective: Competing in the Global Economy

and prosperous than others. And the third, which arose from the second, examines how you can take competitive thinking and apply it to social problems such as the environment, inner cities, and health care. Most of my readers have tended... View Details
Keywords: Re: Michael E. Porter
  • 19 Mar 2013
  • First Look

First Look: March 19

  PublicationsSetting Health Priorities: Strategy versus Tactics Authors:Chu, Michael, David E. Bloom, and Elizabeth Cafiero Publication:Impact: The Magazine of PSI Abstract Health decision makers throughout... View Details
Keywords: Sean Silverthorne
  • 10 Jan 2017
  • First Look

First Look at New Research: January 10, 2017

and provide the impetus for evaluating research on disruptive innovation in management and strategy. We trace disruptive innovation theory’s intellectual history, noting both how core principles have crystallized through a process of anomaly-seeking research and how it... View Details
Keywords: Sean Silverthorne
  • 11 Feb 2019
  • Research & Ideas

The Business of Saving the Planet

"The fact that the benefits of addressing the problem of climate change almost certainly outweigh the costs ... does not make concerted global action to address the problem easy." —Climate Change in 2018: Implications for Business If there is one positive... View Details
Keywords: by Sean Silverthorne; Energy; Green Technology
  • 26 Jul 2016
  • First Look

July 26, 2016

excellence with high-volume experts. Finally, we need better health information technology systems to facilitate knowledge transmission and communication. Publisher's link:... View Details
Keywords: Sean Silverthorne
  • 23 Nov 2010
  • First Look

First Look: November 23

School Case 811-014 The Ze-gen case covers the first five years in the life of a clean-tech start-up. Ze-gen had developed an innovative technology that converted solid waste into synthesis gas (called syngas). This View Details
Keywords: Sean Silverthorne

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