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- All HBS Web
(2,373)
- People (6)
- News (503)
- Research (1,359)
- Events (13)
- Multimedia (10)
- Faculty Publications (722)
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- May 2024
- Article
Tepid Uptake of Digital Health Technologies in Clinical Trials by Pharmaceutical and Medical Device Firms
By: Caroline Marra and Ariel D. Stern
Digital health technologies (DHTs) can enable more patient-centric therapeutic development by generating evidence that captures how patients feel and function, enabling decentralized trial designs that increase participant inclusivity and convenience, and collecting... View Details
Keywords: Health Care and Treatment; Technological Innovation; Product Development; Health Testing and Trials; Governing Rules, Regulations, and Reforms
Marra, Caroline, and Ariel D. Stern. "Tepid Uptake of Digital Health Technologies in Clinical Trials by Pharmaceutical and Medical Device Firms." Clinical Pharmacology & Therapeutics 115, no. 5 (May 2024): 988–992.
- August 2022
- Case
SuperRare: Turning an NFT Marketplace into a DAO
By: Jeffrey J. Bussgang, Scott Duke Kominers and Amy Klopfenstein
In June 2021, John Crain and Jonathan Perkins, the founders of SuperRare, a marketplace for non-fungible tokens (NFTs), contemplate whether to transform their company into a decentralized autonomous organization (DAO). Crain and Perkins founded SuperRare in 2018 to... View Details
Keywords: NFTs; Crypto Economy; Alternative Assets; DAOs; Arts; Governance; Governance Controls; Governing Rules, Regulations, and Reforms; Information Technology; Technology Adoption; Internet and the Web; Digital Platforms; Innovation and Invention; Technological Innovation; Disruptive Innovation; Finance; Currency; Investment; Markets; Auctions; Bids and Bidding; Demand and Consumers; Network Effects; Market Design; Market Transactions; Market Timing; Web Services Industry; North and Central America; United States
Bussgang, Jeffrey J., Scott Duke Kominers, and Amy Klopfenstein. "SuperRare: Turning an NFT Marketplace into a DAO." Harvard Business School Case 823-027, August 2022.
- 2025
- Working Paper
Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances
By: Srikant M. Datar, Amar Bhidé and Katherine Stebbins
This case history describes how Magnetic Resource Imaging (MRI) came to complement – and partially replace -- computed tomography (CT) imaging of soft tissue. Specifically, we chronicle 1) the development of foundational techniques and prototypes (through the 1970s);... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Datar, Srikant M., Amar Bhidé, and Katherine Stebbins. "Magnetic Resonance Imaging—High Quality and Radiation Free: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-001, July 2019. (Revised January 2025.)
- 2025
- Working Paper
Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how the development of x-ray-based techniques and equipment (“mammography”) led to widespread screening for breast cancer and enabled “minimally invasive” biopsies of breast tumors. Specifically, we chronicle how: 1) new protocols and... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Mammography - Early Detection, Precise Diagnoses: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-002, July 2019. (Revised January 2025.)
- 2024
- Working Paper
Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances
By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
This case history describes how a chance discovery of bacteria that infect stomach linings completely changed how physicians treat ulcers. Specifically, we chronicle how: 1) two Australian physicians brought the bacterial infection to the world’s attention and... View Details
Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "Antibiotic Treatments for Ulcers--Eradicating H-Pylori Infections: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-006, July 2019. (Revised May 2024.)
- 13 Nov 2007
- Research & Ideas
Six Steps for Reinvigorating America
innovation and the opportunity to participate in the "white coat" economy and life sciences revolution of the 21st century. Writes a new social contract based on real family values, creating fair and flexible workplaces that are... View Details
Keywords: by Sean Silverthorne
- July 2010
- Article
The Supply Side of Innovation: H-1B Visa Reforms and U.S. Ethnic Invention
By: William R. Kerr and William F. Lincoln
This study evaluates the impact of high-skilled immigrants on U.S. technology formation. We use reduced-form specifications that exploit large changes in the H-1B visa program. Higher H-1B admissions increase immigrant science and engineering (SE) employment and... View Details
Keywords: Engineering; Governing Rules, Regulations, and Reforms; Policy; Immigration; Innovation and Invention; Patents; Business and Government Relations; Science; United States
Kerr, William R., and William F. Lincoln. "The Supply Side of Innovation: H-1B Visa Reforms and U.S. Ethnic Invention." Journal of Labor Economics 28, no. 3 (July 2010): 473–508. (Winner of H. Gregg Lewis Prize for Best Paper in Journal of Labor Economics 2010-2011.)
- 13 Mar 2012
- First Look
First Look: March 13
software and IT service firms will likely have an inward focus over the next five years and will, therefore, only slowly emerge onto the global market. Working PapersThe Role of Organizational Scope and Governance in Strengthening... View Details
Keywords: Sean Silverthorne
- 21 Apr 2020
- Research & Ideas
7 Successful Battle Strategies to Beat COVID-19
teams in territory that models cannot predict. COVID-19 events deliver surprises daily to many organizations, from health care specialists to government officials. The decision-making process that responds to rapid change is once again as... View Details
Keywords: by Euvin Naidoo
- October 1998 (Revised June 2002)
- Case
Austin, Texas: Building a High-Tech Economy
By: Bruce R. Scott and Srinivas Sunder
Members of the community decide to try to diversify the economy of Austin, Texas, by welcoming high-technology firms and by augmenting the electrical engineering faculty at University of Texas--Austin. View Details
Keywords: Development Economics; Diversification; Information Technology; Policy; Government and Politics; Engineering; Technological Innovation; Competitive Advantage; Higher Education; Texas
Scott, Bruce R., and Srinivas Sunder. "Austin, Texas: Building a High-Tech Economy." Harvard Business School Case 799-038, October 1998. (Revised June 2002.)
- November 2024 (Revised May 2025)
- Case
Indonesia Education Reform: Merdeka Belajar ('Emancipated Learning')
By: John Jong-Hyun Kim, Adina Wong, Nancy Hua Dai and Mary C. Sauer
This case is set in 2024 in Indonesia, as Nadiem Makarim, Minister of Education, Culture, Research, and Technology, reflects on his tenure as Minister shortly before stepping down. With the ambition to lift Indonesia out of the middle-income gap by raising K12 to... View Details
Keywords: Education; Change Management; Knowledge Dissemination; Government Administration; Leading Change; Innovation Strategy; Development Economics; Education Industry; Asia; Indonesia
Kim, John Jong-Hyun, Adina Wong, Nancy Hua Dai, and Mary C. Sauer. "Indonesia Education Reform: Merdeka Belajar ('Emancipated Learning')." Harvard Business School Case 325-060, November 2024. (Revised May 2025.)
- 07 Oct 2015
- What Do You Think?
What is the Best Immigration Model for the US?
to return to their countries of origin....” Ben commented that “We have a need for skilled and unskilled labor here (in the U.S.) and we value inclusion and integration... (But) I think our government shouldn’t copy any other country’s... View Details
Keywords: by James Heskett
- 13 Jan 2009
- First Look
First Look: January 13, 2009
Publication:Stanford Social Innovation Review (forthcoming) Abstract The purpose of this paper is to provide a useful, easily applied theory of governance performance. The existing model is fundamentally... View Details
Keywords: Martha Lagace
- 07 Oct 2014
- First Look
First Look: October 7
Publications October 2014 Management Science Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science By: Boudreau, Kevin J., Eva Guinan, Karim Lakhani, and Christoph Riedl Abstract—Selecting among alternative... View Details
Keywords: Sean Silverthorne
- 12 Sep 2011
- Research & Ideas
The Untold Story of ‘Green’ Entrepreneurs
In the 1920s, on pitch black nights in rural eastern Montana, the farmhouse owned by the parents of brothers Marcellus and Joe Jacobs stood out for one reason: it had light, although located far from power lines and gasoline supplies. It was a beacon in the dark that... View Details
Keywords: by Sean Silverthorne
- 22 Apr 2020
- Research Event
How Investors Are Sizing Up Climate Change’s Risks—and Opportunities
Until a few years ago, climate change’s potential impact seemed abstract for many investors. Now, as sea levels rise, hurricanes intensify, and droughts threaten food supplies, many investors are confronting its financial realities. But it’s not a simple calculation.... View Details
- 02 Oct 2012
- First Look
First Look: October 2
information that impacts the formation of scientific collaborations. Download the paper: https://www.hbs.edu/faculty/Pages/item.aspx?num=42946 Technology, Innovation and Economic Growth in Britain Since 1870 Author: Tom Nicholas Abstract This chapter... View Details
Keywords: Sean Silverthorne
- 16 Oct 2013
- Op-Ed
Response to Readers: Combating Climate Change with Nuclear Power and Fracking
With more than 7,500 views and 180-plus tweets, I want to thank everyone for taking the time to read the original HBS Working Knowledge piece, The Case for Combating Climate Change with Nuclear Power and Fracking, and, in particular, for sharing your thoughts with one... View Details
- 16 Jul 2008
- Op-Ed
What Should Employers Do about Health Care?
ignored health care altogether, leaving it to government or dutifully paying their mandated health contributions. Many U.S. employers are dropping health benefits or hoping for reforms that will transfer responsibility for health... View Details
- 05 Jun 2013
- Op-Ed
Corporate Leaders Need to Step Up on Climate Change
Green initiatives are ubiquitous these days, implemented with zeal at companies like Dupont, IBM, Walmart, and Walt Disney. The programs being rolled out—lighting retrofits, zero-waste factories, and carpool incentives—save money and provide a green glow. Most large... View Details
Keywords: by Michael Toffel & Auden Schendler