Publications

January 2006
Case

Jack Strang at SequenceLabs

By: Mukti Khaire, John J. Gabarro and Lynda M. Applegate

How can entrepreneur manage his firm if things go wrong despite having a great idea, a solid team, and financial backing? Jack Strang founded a biotech firm with his friend Peter Evans, to develop molecular pathway-based "cures" for metabolic disorders. The idea was... View Details

Keywords: Corporate Entrepreneurship; Business or Company Management; Venture Capital; Factories, Labs, and Plants; Business Growth and Maturation; Failure; Biotechnology Industry

September 2013 (Revised November 2015)
Case

Living Proof: Are We a Technology Company or a Beauty Company?

By: Willy Shih

Jon Flint came up with the idea of a science-based beauty company while talking with his hairdresser about the problems with typical hair and skin care products. Together with a small team that included Professor Robert Langer of MIT, he committed to assemble a team... View Details

January 2009 (Revised July 2009)
Case

Targanta Therapeutics: Hitting a Moving Target

By: Arthur A. Daemmrich

This case explores regulatory, product testing, and business strategy at Targanta Therapeutics, a biotech company preparing its first new drug application to the FDA. In October 2007, Mark Leuchtenberger, president and CEO of Targanta—which has just held a successful... View Details

Keywords: Decision Choices and Conditions; Entrepreneurship; Governing Rules, Regulations, and Reforms; Health Testing and Trials; Product Development; Business and Government Relations; Business Strategy; Biotechnology Industry; Pharmaceutical Industry

April 2002
Case

In vivo to in vitro to in silico: Coping with Tidal Waves of Data at Biogen

By: Juan Enriquez-Cabot, Gary P. Pisano and Gaye Bok

Biogen is a successful biotech company facing a critical juncture. CEO John Mullen ponders how technological changes introduced into the research function will shape larger corporate decisions. This world in which biotechnology companies operated had changed... View Details

Keywords: Change; Decisions; Product Development; Research and Development; Expansion; Technology; Biotechnology Industry

August 2010 (Revised January 2013)
Case

Avi Kremer

By: Joshua D. Margolis and Mark Wetzel

If you were diagnosed with a terminal illness, how would you respond and what would you do with your remaining time? Avi Kremer contemplates four options for how to devote himself 18 months after being diagnosed with ALS. His experience thus far and the choices he... View Details

Keywords: Entrepreneurship; Values and Beliefs; Health Disorders; Leadership Development; Personal Development and Career; Social Enterprise; Personal Characteristics

October 2009 (Revised August 2014)
Case

Tengion: Bringing Regenerative Medicine to Life

By: Elie Ofek and Polly Ross Ribatt

Tengion is a young biotech company that is at the frontier of regenerative medicine—a nascent field that seeks to promote the creation of new cells and tissue to repair or replace tissue or organ function lost due to age, disease, damage, or congenital defects. In late... View Details

Keywords: Decision Choices and Conditions; Financial Crisis; Entrepreneurship; Health Care and Treatment; Technological Innovation; Product Launch; Product Development; Research and Development; Biotechnology Industry; United States

19 May 2009
First Look

First Look: May 19, 2009

entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The... View Details

Keywords: Martha Lagace

15 Dec 2009
First Look

First Look: Dec. 15, 2009

http://cb.hbsp.harvard.edu/cb/product/510037-PDF-ENG Tengion: Bringing Regenerative Medicine to Life Elie Ofek and Polly Ross RibattHarvard Business School Case 510-031 Tengion is a young biotech company that is at the frontier of... View Details

Keywords: Martha Lagace

15 Oct 2013
First Look

First Look: October 15

science to consumers. It found it increasingly necessary to direct more of its resources towards marketing, including a major investment in Jennifer Aniston as its celebrity spokesperson. Were they becoming less of a biotech company and... View Details

Keywords: Sean Silverthorne

15 Sep 2010
Working Paper Summaries

From Bench to Board: Gender Differences in University Scientists’ Participation in Commercial Science

Keywords: by Waverly W. Ding, Fiona Murray & Toby E. Stuart; Biotechnology

15 May 2007
First Look

First Look: May 15, 2007

Working PapersI'll Have the Ice Cream Soon and the Vegetables Later: Decreasing Impatience over Time in Online Grocery Orders Authors:Todd Rogers, Katherine L. Milkman, and Max H. Bazerman Abstract How do decisions for the near future differ from decisions for the... View Details

Keywords: Martha Lagace

March 2023
Case

Moderna

By: Marco Iansiti, Karim R. Lakhani, Hannah Mayer, Kerry Herman, Allison J. Wigen and Dave Habeeb

This multimedia case follows the story of Moderna and its entry into vaccine development in the wake of the COVID-19 pandemic. In summer 2020, Stephane Bancel, CEO of biotech firm Moderna, faces several challenges as his company races to develop a vaccine for COVID-19.... View Details

Keywords: Health Pandemics; Research and Development; Digital Transformation; Health Testing and Trials; Biotechnology Industry; Pharmaceutical Industry

December 2008 (Revised January 2011)
Case

Arcadia Biosciences: Seeds of Change

By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman

Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details

Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China; India; California

October 2001 (Revised March 2002)
Case

Perlegen Sciences

By: Linda A. Hill and Nicole Tempest

As a biotech start-up company involved in studying human genomes, Perlegen needed to develop an organization that fostered innovation and teamwork among a group of highly trained professionals from both the science and technology fields. Perlegen's CEO, Brad Margus,... View Details

Keywords: Innovation Leadership; Groups and Teams; Management Teams; Problems and Challenges; Business Startups; Genetics; Talent and Talent Management; Innovation Strategy; Biotechnology Industry

February 2022
Case

Leading The UK Vaccine Task Force

By: Amy C. Edmondson and Claudia Pienica

This case describes the first six months of the UK Vaccine Taskforce, under the leadership of Kate Bingham. With a career spent in the private sector as a biotech investor, Bingham’s appointment within the government was considered unusual. The overarching brief given... View Details

June 2014 (Revised February 2017)
Case

Kathy Giusti and the Multiple Myeloma Research Foundation

By: Richard G. Hamermesh, Joshua D. Margolis and Matthew G. Preble

What do you do when your rising professional career is cut short by an unexpected cancer diagnosis? Kathy Giusti shifted careers, built a new organization that transformed how cancer research is done, and now faces the challenge of sustaining the organization and its... View Details