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      • Faculty Publications  (981)

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      • 2024
      • Working Paper

      Anytime-Valid Inference in Linear Models and Regression-Adjusted Causal Inference

      By: Michael Lindon, Dae Woong Ham, Martin Tingley and Iavor I. Bojinov
      Linear regression adjustment is commonly used to analyze randomized controlled experiments due to its efficiency and robustness against model misspecification. Current testing and interval estimation procedures leverage the asymptotic distribution of such estimators to... View Details
      Keywords: Mathematical Methods; Analytics and Data Science
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      Lindon, Michael, Dae Woong Ham, Martin Tingley, and Iavor I. Bojinov. "Anytime-Valid Inference in Linear Models and Regression-Adjusted Causal Inference." Harvard Business School Working Paper, No. 24-060, March 2024.
      • 2024
      • Working Paper

      Design of Panel Experiments with Spatial and Temporal Interference

      By: Tu Ni, Iavor Bojinov and Jinglong Zhao
      One of the main practical challenges companies face when running experiments (or A/B tests) over a panel is interference, the setting where one experimental unit's treatment assignment at one time period impacts another's outcomes, possibly at the following time... View Details
      Keywords: Research
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      Ni, Tu, Iavor Bojinov, and Jinglong Zhao. "Design of Panel Experiments with Spatial and Temporal Interference." Harvard Business School Working Paper, No. 24-058, March 2024.
      • 2023
      • Working Paper

      Design-Based Inference for Multi-arm Bandits

      By: Dae Woong Ham, Iavor I. Bojinov, Michael Lindon and Martin Tingley
      Multi-arm bandits are gaining popularity as they enable real-world sequential decision-making across application areas, including clinical trials, recommender systems, and online decision-making. Consequently, there is an increased desire to use the available... View Details
      Keywords: Analytics and Data Science; Mathematical Methods
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      Ham, Dae Woong, Iavor I. Bojinov, Michael Lindon, and Martin Tingley. "Design-Based Inference for Multi-arm Bandits." Harvard Business School Working Paper, No. 24-056, March 2024.
      • 2025
      • Working Paper

      Exports in Disguise? Trade Rerouting During the U.S.-China Trade War

      By: Ebehi Iyoha, Edmund Malesky, Jaya Wen and Sung-Ju Wu
      This paper introduces a new measure of tariff evasion through rerouting and applies it to the 2018 U.S.–China trade war, focusing on Vietnam as a transit country. We use transaction-level trade data and define rerouting as the flow of a granular eight-digit Harmonized... View Details
      Keywords: Trade; International Relations; Logistics; China; Viet Nam; United States
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      Iyoha, Ebehi, Edmund Malesky, Jaya Wen, and Sung-Ju Wu. "Exports in Disguise? Trade Rerouting During the U.S.-China Trade War." Harvard Business School Working Paper, No. 24-072, May 2024. (Revised March 2025.)
      • March 2024
      • Article

      Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act

      By: Matthew Vogel, Pragya Kakani, Amitabh Chandra and Rena M. Conti
      The Inflation Reduction Act (IRA) requires Medicare to negotiate lower prices for some medicines with high Medicare spending. Using historical data from public and proprietary sources to apply the IRA's negotiation criteria retrospectively, we identify all drugs that... View Details
      Keywords: Policy; Government Legislation; Health Care and Treatment; Negotiation; Price; Pharmaceutical Industry
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      Vogel, Matthew, Pragya Kakani, Amitabh Chandra, and Rena M. Conti. "Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act." Nature Biotechnology 42, no. 3 (March 2024): 406–412.
      • 2024
      • Working Paper

      Cicely Saunders and Modern Hospices—A Brother’s View: Case Histories of Transformational Advances

      By: Amar Bhide and Srikant M. Datar
      This case history describes the role of Dame Cicely Saunders (1918-2005) in shaping the modern hospice movement. View Details
      Keywords: Health Care and Treatment; Power and Influence
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      Bhide, Amar, and Srikant M. Datar. "Cicely Saunders and Modern Hospices—A Brother’s View: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 24-055, February 2024. (Revised May 2024.)
      • February 2024 (Revised December 2024)
      • Case

      Best Buy Health: Enabling Care at Home

      By: Robert S. Huckman, Rosabeth Moss Kanter, Antonio Moreno, Bradley Staats and Sarah Mehta
      This case explores retailer Best Buy’s decision to enter health care. Best Buy Health aims to enable care at home across three prongs: consumer health, active aging, and virtual care. A key pillar of Best Buy Health's strategy is leveraging the Geek Squad—the company's... View Details
      Keywords: Business Ventures; Health Care and Treatment; Innovation and Invention; Business Strategy; Market Entry and Exit; Service Delivery; Service Operations; Electronics Industry; Health Industry; Retail Industry; United States; Minnesota
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      Huckman, Robert S., Rosabeth Moss Kanter, Antonio Moreno, Bradley Staats, and Sarah Mehta. "Best Buy Health: Enabling Care at Home." Harvard Business School Case 624-009, February 2024. (Revised December 2024.)
      • 2023
      • Working Paper

      'De Gustibus' and Disputes about Reference Dependence

      By: Thomas Graeber, Pol Campos-Mercade, Lorenz Goette, Alexandre Kellogg and Charles Sprenger
      Existing tests of reference-dependent preferences assume universal loss aversion. This paper examines the implications of heterogeneity in gain-loss attitudes for such tests. In experiments on labor supply and exchange behavior we measure gain-loss attitudes and then... View Details
      Keywords: Behavioral Economics; Decision Choices and Conditions; Forecasting and Prediction
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      Graeber, Thomas, Pol Campos-Mercade, Lorenz Goette, Alexandre Kellogg, and Charles Sprenger. "'De Gustibus' and Disputes about Reference Dependence." Harvard Business School Working Paper, No. 24-046, January 2024.
      • February 2024
      • Case

      Compass Pathways: Pioneering Psychedelic Treatment

      By: Tiona Zuzul, Kisha Lashley and Gamze Yucaoglu
      This case follows Compass Pathways, a pioneering company developing treatment for depression based on psilocybin, the compound found in ‘magic mushrooms.’ Psilocybin was a federally illegal substance in the U.S., and a “Schedule I” drug, defined as a drug “with no... View Details
      Keywords: Commercialization; Corporate Strategy; Competitive Strategy; Product Launch; Health Testing and Trials; Research and Development; Laws and Statutes; Pharmaceutical Industry; Europe; United States; United Kingdom
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      Zuzul, Tiona, Kisha Lashley, and Gamze Yucaoglu. "Compass Pathways: Pioneering Psychedelic Treatment." Harvard Business School Case 724-412, February 2024.
      • January 19, 2024
      • Article

      Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder

      By: Robert S. Kaplan and Sarah E. Wakeman
      U.S. overdose deaths currently exceed 100,000 per year. New facilities, known as bridge clinics, are broadening access to high-quality care by offering outpatient substance use disorder (SUD) treatment with few access barriers. But many of the critical services offered... View Details
      Keywords: Health Care and Treatment; Cost; Adoption
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      Kaplan, Robert S., and Sarah E. Wakeman. "Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder." Health Affairs Forefront (January 19, 2024).
      • January 2024
      • Background Note

      Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?

      By: Regina E. Herzlinger and James Wallace
      How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.

      This note and "Health Stop (A): What Type... View Details
      Keywords: Business Model; Health Care and Treatment; Collaborative Innovation and Invention; Mission and Purpose; Alignment; Health Industry
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      Herzlinger, Regina E., and James Wallace. "Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?" Harvard Business School Background Note 324-037, January 2024.
      • January 2024
      • Article

      A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

      By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan
      The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details
      Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry
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      Wakeman, Sarah E., Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe, and Robert S. Kaplan. "A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder." Journal of Behavioral Health Services & Research 51, no. 1 (January 2024): 22–30.
      • January 2024
      • Article

      Cost of Exempting Sole Orphan Drugs from Medicare Negotiation

      By: Matthew Vogel, Olivia Zhao, William B. Feldman, Amitabh Chandra, Aaron S. Kesselheim and Benjamin N. Rome
      Importance: The Inflation Reduction Act (IRA) requires Medicare to negotiate prices for some high-spending drugs but exempts drugs approved solely for the treatment of a single rare disease.
      Objective: To estimate Medicare spending and global... View Details
      Keywords: Health Care and Treatment; Insurance; Price; Health Industry
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      Vogel, Matthew, Olivia Zhao, William B. Feldman, Amitabh Chandra, Aaron S. Kesselheim, and Benjamin N. Rome. "Cost of Exempting Sole Orphan Drugs from Medicare Negotiation." JAMA Internal Medicine 184, no. 1 (January 2024): 63–69.
      • January 2024
      • Article

      Fencing Off Silicon Valley: Cross-Border Venture Capital and Technology Spillovers

      By: Ufuk Akcigit, Sina T. Ates, Josh Lerner, Richard Townsend and Yulia Zhestkova
      The treatment of foreign investors is a contentious topic in U.S. entrepreneurship policy. We model a setting where foreign corporate investments in Silicon Valley may allow U.S. entrepreneurs to pursue technologies that they could not otherwise, but may also lead to... View Details
      Keywords: Innovation; Corporate Venture Capital; Knowledge Spillovers; Foreign Direct Investment; Innovation and Invention; Venture Capital; Entrepreneurship; Policy
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      Akcigit, Ufuk, Sina T. Ates, Josh Lerner, Richard Townsend, and Yulia Zhestkova. "Fencing Off Silicon Valley: Cross-Border Venture Capital and Technology Spillovers." Journal of Monetary Economics 141 (January 2024): 14–39.
      • January 2024
      • Article

      Population Interference in Panel Experiments

      By: Kevin Wu Han, Guillaume Basse and Iavor Bojinov
      The phenomenon of population interference, where a treatment assigned to one experimental unit affects another experimental unit’s outcome, has received considerable attention in standard randomized experiments. The complications produced by population interference in... View Details
      Keywords: Outcome or Result; Research; Situation or Environment
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      Han, Kevin Wu, Guillaume Basse, and Iavor Bojinov. "Population Interference in Panel Experiments." Journal of Econometrics 238, no. 1 (January 2024).
      • January–February 2024
      • Article

      Shared Service Delivery Can Increase Client Engagement: A Study of Shared Medical Appointments

      By: Ryan W. Buell, Kamalini Ramdas, Nazlı Sönmez, Kavitha Srinivasan and Rengaraj Venkatesh
      Problem Definition: Clients and service providers alike often consider one-on-one service delivery to be ideal, assuming – perhaps unquestioningly – that devoting individualized attention best improves client outcomes. In contrast, in shared service delivery, clients... View Details
      Keywords: Health Care and Treatment; Customer Satisfaction; Outcome or Result; Performance Improvement
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      Buell, Ryan W., Kamalini Ramdas, Nazlı Sönmez, Kavitha Srinivasan, and Rengaraj Venkatesh. "Shared Service Delivery Can Increase Client Engagement: A Study of Shared Medical Appointments." Manufacturing & Service Operations Management 26, no. 1 (January–February 2024): 154–166.
      • 2023
      • Working Paper

      Money, Time, and Grant Design

      By: Kyle Myers and Wei Yang Tham
      The design of research grants has been hypothesized to be a useful tool for influencing researchers and their science. We test this by conducting two thought experiments in a nationally representative survey of academic researchers. First, we offer participants a... View Details
      Keywords: Research; Power and Influence; Money
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      Myers, Kyle, and Wei Yang Tham. "Money, Time, and Grant Design." Harvard Business School Working Paper, No. 24-037, December 2023.
      • December 2023
      • Teaching Note

      Buurtzorg

      By: Ethan Bernstein and Tatiana Sandino
      Teaching Note for HBS Case No. 122-101. As co-founders of home nursing company Buurtzorg, Jos de Blok and Gonnie Kronenberg prized both self-management and organizational learning. Buurtzorg’s 10,000 nurses across 950 neighborhood nursing teams in the Netherlands were... View Details
      Keywords: Health Care and Treatment; Employee Relationship Management; Knowledge Dissemination; Knowledge Management; Management Practices and Processes; Organizational Design; Organizational Structure; Groups and Teams; Learning; Health Industry; Netherlands
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      Bernstein, Ethan, and Tatiana Sandino. "Buurtzorg." Harvard Business School Teaching Note 124-059, December 2023.
      • 2025
      • Working Paper

      Enhancing Treatment Effect Prediction on Privacy-Protected Data: An Honest Post-Processing Approach

      By: Ta-Wei Huang and Eva Ascarza
      As firms increasingly rely on customer data for personalization, concerns over privacy and regulatory compliance have grown. Local Differential Privacy (LDP) offers strong individual-level protection by injecting noise into data before collection. While... View Details
      Keywords: Targeted Intervention; Conditional Average Treatment Effect Estimation; Differential Privacy; Honest Estimation; Post-processing; Analytics and Data Science; Consumer Behavior; Marketing
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      Huang, Ta-Wei, and Eva Ascarza. "Enhancing Treatment Effect Prediction on Privacy-Protected Data: An Honest Post-Processing Approach." Harvard Business School Working Paper, No. 24-034, December 2023. (Revised March 2025.)
      • December 12, 2023
      • Article

      Prices for Common Services at Quaternary vs Nonquaternary Hospitals

      By: Brandon W. Yan, Maximilian J. Pany and Leemore S. Dafny
      Using commercial health insurance claims data from 2017-2019, we assessed whether quaternary hospitals charged higher prices for common, unspecialized services also offered by nonquaternary hospitals. We found quaternary-hospital price premiums of 8.2 percent, on... View Details
      Keywords: Price; Health Care and Treatment; Insurance; Markets; Health Industry
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      Yan, Brandon W., Maximilian J. Pany, and Leemore S. Dafny. "Prices for Common Services at Quaternary vs Nonquaternary Hospitals." JAMA, the Journal of the American Medical Association 330, no. 22 (December 12, 2023): 2211–2213.
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