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      • December 2024
      • Case

      Xtalic

      By: Joshua Lev Krieger and Jim Matheson
      This case study examines the commercialization efforts of Xtalic, a startup founded by MIT scientists based on their discovery of a novel material science method to protect metal substrates. The case focuses on the strategic decisions involved in bringing this... View Details
      Keywords: Innovation & Entrepreneurship; Innovation and Management; Entrepreneurial Finance; Entrepreneurship; Business Model; Business Startups; Agreements and Arrangements; Science-Based Business; Commercialization
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      Krieger, Joshua Lev, and Jim Matheson. "Xtalic." Harvard Business School Case 825-103, December 2024.
      • December 2024 (Revised January 2025)
      • Technical Note

      A Guide to the Vocabulary, Evolution, and Impact of Artificial Intelligence (AI)

      By: Shane Greenstein, Nathaniel Lovin, Scott Wallsten, Kerry Herman and Susan Pinckney
      A note on the vocabulary, evolution, and impact of AI. View Details
      Keywords: Artificial Intelligence; Software; AI and Machine Learning; Technology Adoption; Technological Innovation; Technology Industry
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      Greenstein, Shane, Nathaniel Lovin, Scott Wallsten, Kerry Herman, and Susan Pinckney. "A Guide to the Vocabulary, Evolution, and Impact of Artificial Intelligence (AI)." Harvard Business School Technical Note 625-039, December 2024. (Revised January 2025.)
      • December 2024
      • Case

      Blue Cross Blue Shield of Michigan (BCBSM): The AI Journey

      By: Shikhar Ghosh
      In early 2024, Bill Fandrich, Executive VP and CIO of Blue Cross Blue Shield of Michigan (BCBSM), faced a critical decision about AI adoption within the organization. Fandrich had championed AI implementation at BCBSM. After successfully developing three AI... View Details
      Keywords: Blue Cross; Automation; Generative Ai; Health Insurance; Insurance Companies; Innovation; IT Strategy; Organizational Transformations; Technology; Non-profit; AI and Machine Learning; Health; Digital Strategy; Digital Transformation; Leadership; Technology Adoption; Job Cuts and Outsourcing; Innovation Strategy; Health Industry; Insurance Industry; Michigan
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      Ghosh, Shikhar. "Blue Cross Blue Shield of Michigan (BCBSM): The AI Journey." Harvard Business School Case 825-082, December 2024.
      • November 2024
      • Case

      AlphaGo (A): Birth of a New Intelligence

      By: Shikhar Ghosh and Shweta Bagai
      This case, the first of a three-part series, traces DeepMind's evolution from its 2010 founding through its acquisition by Google in 2014. Often referred to as the "Apollo project" of artificial intelligence, DeepMind used games as a testing ground to develop AI... View Details
      Keywords: AI and Machine Learning; Technology Adoption; Games, Gaming, and Gambling; Technological Innovation; Creativity; Technology Industry; South Korea; China; United States
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      Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (A): Birth of a New Intelligence." Harvard Business School Case 825-073, November 2024.
      • November 2024
      • Supplement

      AlphaGo (B): Birth of a New Intelligence

      By: Shikhar Ghosh and Shweta Bagai
      This case, the second in a three-part series, explores DeepMind's evolution from developing game-specific AI to more generalized learning systems. Following AlphaGo's 2017 victory over the Go world champion, DeepMind introduced two revolutionary systems that eliminated... View Details
      Keywords: AI and Machine Learning; Games, Gaming, and Gambling; Technological Innovation; Disruptive Innovation; Innovation Leadership; Information Technology Industry; United States; Russia; China
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      Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (B): Birth of a New Intelligence." Harvard Business School Supplement 825-074, November 2024.
      • November 2024
      • Supplement

      AlphaGo (C): Birth of a New Intelligence

      By: Shikhar Ghosh and Shweta Bagai
      This case, the final of a three-part series, explores DeepMind's pivotal transition from mastering games to solving real-world scientific challenges. In December 2020, DeepMind's AI system AlphaFold 2 achieved a breakthrough by solving protein folding—a 50-year-old... View Details
      Keywords: Autonomy; Deep Learning; Drug Discovery; Healthcare Innovation; Neural Networks; Scientific Research; Technology Startup; AI and Machine Learning; Technological Innovation; Research and Development; Business Model; Business Strategy; Open Source Distribution; Technology Industry; United States
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      Ghosh, Shikhar, and Shweta Bagai. "AlphaGo (C): Birth of a New Intelligence." Harvard Business School Supplement 825-075, November 2024.
      • November 2024
      • Case

      Polish Agro: Where Do We Grow from Here?

      By: Willy C. Shih, Lena Duchene and Daniela Beyersdorfer
      By July 2024, Polish Agro had grown into one of Poland’s fastest-growing agribusinesses, with €230 million in revenue, 82 employees, and operations across Northern Poland. The company supported farmers with essential agricultural inputs like fertilizers and seeds,... View Details
      Keywords: Plant-Based Agribusiness; Distribution; Volatility; Customer Focus and Relationships; Customer Value and Value Chain; Climate Change; Environmental Regulation; Profit; Trade; Digital Strategy; Innovation Strategy; Crisis Management; Growth and Development Strategy; Resource Allocation; Advertising; Brands and Branding; E-commerce; Business and Community Relations; Networks; Adaptation; Adoption; Competitive Advantage; Business Model; Health Pandemics; War; Agriculture and Agribusiness Industry; Europe; Poland
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      Shih, Willy C., Lena Duchene, and Daniela Beyersdorfer. "Polish Agro: Where Do We Grow from Here?" Harvard Business School Case 625-061, November 2024.
      • November 2024 (Revised January 2025)
      • Case

      MiDAS: Automating Unemployment Benefits

      By: Shikhar Ghosh and Shweta Bagai
      In 2015, the state of Michigan considered whether to nominate its Michigan Integrated Data Automated System (MiDAS) for a prestigious state technology award. Launched in 2013 amid severe budget pressures, the $47 million automated fraud detection system was designed to... View Details
      Keywords: Artificial Intelligence; AI; Machine Learning Models; Algorithmic Data; Automation; Benefits; Compensation; Cost Reduction; Government; Fraud; Government Technology; Public Sector; Systems; Systems Integration; Unemployment Insurance; Waste Heat Recovery; AI and Machine Learning; Government Administration; Insurance; Decision Making; Digital Transformation; Employment; Public Administration Industry; United States; Michigan
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      Ghosh, Shikhar, and Shweta Bagai. "MiDAS: Automating Unemployment Benefits." Harvard Business School Case 825-100, November 2024. (Revised January 2025.)
      • 2024
      • Working Paper

      Climate Solutions, Transition Risk, and Stock Returns

      By: Shirley Lu, Edward J. Riedl, Simon Xu and George Serafeim
      Using large language models to measure firms' climate solution products and services, we find that high-climate solution firms exhibit lower stock returns and higher market valuation multiples. Their stock prices respond positively to events signaling increased demand... View Details
      Keywords: Technology; Generative Ai; Large Language Models; Climate Finance; Climate Change; Innovation and Invention; Environmental Sustainability; AI and Machine Learning; Investment; Financial Markets
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      Lu, Shirley, Edward J. Riedl, Simon Xu, and George Serafeim. "Climate Solutions, Transition Risk, and Stock Returns." Harvard Business School Working Paper, No. 25-024, November 2024.
      • November 2024 (Revised December 2024)
      • Case

      Moonfare and the Democratization of Private Equity

      By: Victoria Ivashina and Srimayi Mylavarapu
      Founded in 2016, Moonfare headquartered in Europe, was a pioneer in the “democratization” of private equity investments. Historically, private equity was accessible only to institutional investors like pension funds, endowments, sovereign wealth funds, and large family... View Details
      Keywords: Private Equity; Customers; Wealth; Business Strategy; Segmentation; Technological Innovation; Product Launch; Financial Services Industry; Europe
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      Ivashina, Victoria, and Srimayi Mylavarapu. "Moonfare and the Democratization of Private Equity." Harvard Business School Case 225-044, November 2024. (Revised December 2024.)
      • November 2024
      • Teaching Note

      Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams

      By: Debora L. Spar and Julia M. Comeau
      Teaching Note for HBS Case No. 323-039. In 1990, satellite expert and Sirius XM founder Martine Rothblatt was determined to save the life of her seven-year-old daughter, Jenesis, who was diagnosed with a terminal illness called Pulmonary Arterial Hypertension (PAH). At... View Details
      Keywords: Pharmaceutical Companies; Technological And Scientific Innovation; Organ Donation; Health Care and Treatment; Health Disorders; Innovation and Invention; Growth and Development Strategy; Product Development; Pharmaceutical Industry; Medical Devices and Supplies Industry; United States; District of Columbia
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      Spar, Debora L., and Julia M. Comeau. "Martine Rothblatt and United Therapeutics: A Series of Implausible Dreams." Harvard Business School Teaching Note 325-058, November 2024.
      • 2024
      • Working Paper

      Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups

      By: Shirley Lu, George Serafeim and Simon Xu
      We study whether incumbent firms increase their product focus on climate solutions in response to venture capital (VC) financing of climate-tech startups. Using large language models to measure a firm's focus on climate solutions, we find that incumbents in similar... View Details
      Keywords: Climate Finance; Climate Change; Technological Innovation; Entrepreneurship; Venture Capital; Private Equity; Environmental Sustainability; Business Startups
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      Lu, Shirley, George Serafeim, and Simon Xu. "Catalysts for Climate Solutions: Corporate Responses to Venture Capital Financing of Climate-tech Startups." Harvard Business School Working Paper, No. 25-025, November 2024.
      • October 2024
      • Teaching Plan

      Teamworks: Tackling a Forecasting Fumble

      By: Lou Shipley and Stacy Straaberg
      In late March 2018, Teamworks CEO Zach Maurides learned Q1 2018 sales were at risk for a large forecasting miss. Founded in 2004, Teamworks’s software application assisted support staff in messaging, scheduling, and sharing documents with collegiate and professional... View Details
      Keywords: Acquisition; Business Growth and Maturation; Communication Strategy; Decisions; Forecasting and Prediction; Business Cycles; Technological Innovation; Sports; Growth and Development Strategy; Resource Allocation; Marketing; Sales; Business Strategy; Expansion; Technology Industry; Technology Industry; United States; North Carolina
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      Shipley, Lou, and Stacy Straaberg. "Teamworks: Tackling a Forecasting Fumble." Harvard Business School Teaching Plan 825-003, October 2024.
      • October 2024
      • Case

      Tonik

      By: Andy Wu, Maliha Malek Quadir and Aticus Peterson
      This case study examines Tonik, the first digital bank in the Philippines, as it navigates the challenges of scaling its lending operations and achieving profitability in an evolving fintech landscape. It explores Tonik's journey from its launch in 2018 to early 2024,... View Details
      Keywords: Business Startups; Financing and Loans; Profit; Governing Rules, Regulations, and Reforms; Growth and Development Strategy; Emerging Markets; Entrepreneurship; Product; Technology Industry; Technology Industry; Technology Industry; Philippines
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      Wu, Andy, Maliha Malek Quadir, and Aticus Peterson. "Tonik." Harvard Business School Case 725-404, October 2024.
      • October 2024 (Revised April 2025)
      • Case

      Nvidia

      By: Andy Wu and Matt Higgins
      This case study examines Nvidia's strategic pivot from gaming GPUs to becoming a leader in general-purpose computing and AI. It explores how Nvidia leveraged its GPU architecture to dominate the growing fields of data center acceleration and AI training, outpacing... View Details
      Keywords: Strategy; Technological Innovation; AI and Machine Learning; Product Development; Technology Industry; Technology Industry; Technology Industry; United States; China; Taiwan
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      Wu, Andy, and Matt Higgins. "Nvidia." Harvard Business School Case 725-383, October 2024. (Revised April 2025.)
      • October 2024
      • Case

      Parexel: Scaling Up and Industry Dynamics

      By: Regina E. Herzlinger and Ben Creo
      Through the lens of biopharmaceutical contract research organization (CRO) PAREXEL, this case traces the evolution of the firm as it reinvents itself in response to the transformation of the CRO sector from a small, secondary cluster of firms into a major player with... View Details
      Keywords: Research; Innovation and Invention; Business Model; Transformation; Globalization; Information Technology; Competitive Advantage; Pharmaceutical Industry
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      Herzlinger, Regina E., and Ben Creo. "Parexel: Scaling Up and Industry Dynamics." Harvard Business School Case 325-046, October 2024.
      • October 2024 (Revised November 2024)
      • Case

      SWEN Blue Ocean: Impact Investing Goes to Sea

      By: Vikram S Gandhi and David Allen
      In August 2023, SWEN Blue Ocean, a €170 million impact fund that invested in startups contributing to ocean sustainability, faced a critical investment decision. Part of SWEN Capital Partners, an €8 billion, Paris-based private equity fund, Blue Ocean was co-founded in... View Details
      Keywords: Communication Technology; Environmental Sustainability; Green Technology; Venture Capital; Private Equity; Investment Funds; Science-Based Business; Technological Innovation; Financial Services Industry; France; Paris; Italy
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      Gandhi, Vikram S., and David Allen. "SWEN Blue Ocean: Impact Investing Goes to Sea." Harvard Business School Case 325-013, October 2024. (Revised November 2024.)
      • October 2024
      • Case

      Reed Group and Succession in a Family Business: An Impossible Job to Fill?

      By: Lauren H. Cohen and Tonia Labruyere
      James Reed had taken over Reed Group, the recruitment and career services company his father had founded and built, in 1994. He was now reflecting on succession planning and other challenges that lay ahead: with no obvious choice among his family members, he needed to... View Details
      Keywords: Charity; Succession Planning; Family Business; Values and Beliefs; Management Succession; Mission and Purpose; Family Ownership; Philanthropy and Charitable Giving; Family and Family Relationships; Recruitment; AI and Machine Learning; Employment Industry; United Kingdom; London
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      Cohen, Lauren H., and Tonia Labruyere. "Reed Group and Succession in a Family Business: An Impossible Job to Fill?" Harvard Business School Case 825-084, October 2024.
      • October 2024
      • Course Overview Note

      Risks, Opportunities, and Investments in the Era of Climate Change (ROICC)

      By: George Serafeim
      This course overview note introduces the course Risks, Opportunities, and Investments in the Era of Climate Change to students. View Details
      Keywords: Environment; Innovation; Technology; General Management; Organizational Transformations; Investments; Entrepreneurship; Strategy; Finance; Accounting; Leadership; Climate Change; Environmental Sustainability; Management
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      Serafeim, George. "Risks, Opportunities, and Investments in the Era of Climate Change (ROICC)." Harvard Business School Course Overview Note 125-052, October 2024.
      • October 2024
      • Article

      Global Mobile Inventors

      By: Dany Bahar, Prithwiraj Choudhury, Ernest Miguelez and Sara Signorelli
      The number of Global Mobile Inventors (GMIs), inventors moving across borders during their career, has increased more than tenfold over the past two decades, and the corridors of mobility have shifted towards a growing presence of emerging markets. We document that... View Details
      Keywords: Emerging Markets; Immigration; Patents; Knowledge; Technological Innovation
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      Bahar, Dany, Prithwiraj Choudhury, Ernest Miguelez, and Sara Signorelli. "Global Mobile Inventors." Art. 103357. Journal of Development Economics 171 (October 2024).
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