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Show Results For
- All HBS Web
(605)
- People (1)
- News (149)
- Research (337)
- Events (14)
- Multimedia (4)
- Faculty Publications (129)
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- 13 Sep 2021
- Research & Ideas
Science: The Unlikely Frontier for New Business Ideas
run in-house labs to reap the benefits. Referencing the methods and results of formal scientific research is enough to lift a patent’s value. Defining a product’s ‘science intensity’ Krieger, Watzinger, and... View Details
Keywords: by Avery Forman
- Article
One Obstacle to Curing Cancer: Patient Data Isn't Shared
By: Richard G. Hamermesh and Kathy Giusti
Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details
Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States
Hamermesh, Richard G., and Kathy Giusti. "One Obstacle to Curing Cancer: Patient Data Isn't Shared." Harvard Business Review (website) (November 28, 2016).
- 01 Nov 2022
- Cold Call Podcast
Marie Curie: A Case Study in Breaking Barriers
Keywords: Re: Robert Simons
- 2003
- Case
Corning Microarray Technologies
By: Vijay Govindarajan, Chris Trimble and Gautam Bellur
In mid-2000, the scientific community reached a momentous milestone—the complete mapping of the human genome. Researchers in the field of genomics were anxious to dig into a tremendous array of newly possible scientific inquiries, and needed efficient experimental... View Details
- October 2016
- Article
Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science
By: Kevin J. Boudreau, Eva Guinan, Karim R. Lakhani and Christoph Riedl
Selecting among alternative innovative projects is a core management task in all innovating organizations. In this paper, we focus on the evaluation of frontier scientific research projects. We argue that the "intellectual distance" between the knowledge embodied in... View Details
Keywords: Knowledge; Innovation; Novelty; Evaluation; Resource Allocation; Decision Choices and Conditions; Innovation and Management; Science-Based Business; Experience and Expertise
Boudreau, Kevin J., Eva Guinan, Karim R. Lakhani, and Christoph Riedl. "Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science." Management Science 62, no. 10 (October 2016).
- 2024
- Working Paper
The Wandering Scholars: Understanding the Heterogeneity of University Commercialization
By: Josh Lerner, Henry Manley, Carolyn Stein and Heidi Williams
University-based scientific research has long been argued to be a central source of
commercial innovation and economic growth. Yet at the same time, there have been
long-held concerns that many university-based discoveries never realize their potential
social... View Details
Lerner, Josh, Henry Manley, Carolyn Stein, and Heidi Williams. "The Wandering Scholars: Understanding the Heterogeneity of University Commercialization." Harvard Business School Working Paper, No. 24-043, January 2024. (Econometrica, Conditionally Accepted. Earlier version distributed as National Bureau of Economic Research Working Paper No. 31898 and Harvard Business School Working Paper No. 24-043. Related discussion published as “The Commercialisation of University Research: The Role of People versus Place,” VoxEU, 2024.)
- 26 Feb 2015 - 28 Feb 2015
- Conference Presentation
Is That All There Is to Happiness?
By: J. Phillips, C. Mott, Julian De Freitas, J. Gruber and J. Knobe
Happiness researchers have started to converge on a conception of
happiness that involves some combination of high positive affect,
low negative affect, and high life satisfaction. We present three
studies which demonstrate that the ordinary understanding... View Details
- 2015
- Book
Presence: Bringing Your Boldest Self to Your Biggest Challenges
By: Amy Cuddy
We often meet life's challenges with fear and anxiety. We fail to be our best and end up feeling regretful and powerless. In Presence, Amy Cuddy presents a scientifically grounded way to align our speech and nonverbal behavior with our beliefs, abilities, and... View Details
Cuddy, Amy. Presence: Bringing Your Boldest Self to Your Biggest Challenges. New York: Little, Brown and Company, 2015.
- 2009
- Chapter
Entrepreneurship and the History of Globalization
By: G. Jones and R. Daniel Wadhwani
In this article, we build on the recent efforts of scholars to reintroduce entrepreneurship into the research agenda of business historians. We examine the value and limitations of adapting recent social scientific theories and methods on entrepreneurship to research... View Details
- September 2024
- Article
Standing on the Shoulders of Science
By: Joshua Lev Krieger, Monika Schnitzer and Martin Watzinger
Today’s innovations rely on scientific discoveries of the past, yet only some corporate
R&D builds directly on scientific output. In this paper, we analyze U.S. patents to
investigate how firms generate value by building on prior art “closer” to science. We
show... View Details
Krieger, Joshua Lev, Monika Schnitzer, and Martin Watzinger. "Standing on the Shoulders of Science." Strategic Management Journal 45, no. 9 (September 2024): 1670–1695.
- 2025
- Working Paper
Money, Time, and Grant Design
By: Kyle Myers and Wei Yang Tham
We conduct survey experiments to test how the design of scientific grants—
the money and time awarded—can be used to manage researchers. On average,
researchers are relatively unwilling to trade off money for time when choosing
among grants. However, there is... View Details
Myers, Kyle, and Wei Yang Tham. "Money, Time, and Grant Design." Harvard Business School Working Paper, No. 24-037, December 2023. (Revised June 2025.)
- April 2012
- Case
Danish National Advanced Technology Foundation
By: Willy Shih and Margaret Pierson
Danish National Advanced Technology Foundation (DNATF), a government agency, invests in public-private partnerships to stimulate commercialization of Danish scientific research within the country's industry. DNATF established a process for evaluating proposals, making... View Details
Keywords: Leadership; Commercialization; Management Practices and Processes; Experience and Expertise; Innovation and Invention; Public Ownership; Business and Government Relations; Technology Industry; Denmark
Shih, Willy, and Margaret Pierson. "Danish National Advanced Technology Foundation." Harvard Business School Case 612-091, April 2012.
- 20 Nov 2006
- Research & Ideas
Open Source Science: A New Model for Innovation
scientific problem solving? Yes, and it comes from an unexpected and unrelated corner of the universe: open source software development. That's the view of Karim R. Lakhani, an assistant professor at Harvard Business School with an... View Details
Keywords: by Martha Lagace
- September 2008
- Case
Pfizer Inc: Building an Innovation Center
By: Stefan H. Thomke and Ashok Nimgade
The case describes Pfizer's efforts to build and run an innovation center in Cambridge, Massachusetts. As the center goes through different periods of leadership and strategic models, its relationship with the corporation and other research sites is explored. The case... View Details
Keywords: Innovation and Management; Innovation Strategy; Leadership; Organizational Culture; Research and Development; Pharmaceutical Industry; Cambridge
Thomke, Stefan H., and Ashok Nimgade. "Pfizer Inc: Building an Innovation Center." Harvard Business School Case 609-037, September 2008.
- November 2006 (Revised March 2008)
- Case
The Harvard Stem Cell Institute
Describes a set of issues confronting the leaders of the Harvard Stem Cell Institute, an innovative cross-university effort to accelerate scientific discovery and translation in the domain of stem cells. Covers a wide range of topics, including understanding how... View Details
Keywords: Talent and Talent Management; Higher Education; Entrepreneurship; Collaborative Innovation and Invention; Intellectual Property; Research and Development; Genetics; Biotechnology Industry; Health Industry; Massachusetts
Sahlman, William A. "The Harvard Stem Cell Institute." Harvard Business School Case 807-096, November 2006. (Revised March 2008.)
- March 2010 (Revised May 2012)
- Case
Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration
By: Karim R. Lakhani and Paul R. Carlile
This case presents the Myelin Repair Foundation's accelerated research collaboration model for drug discovery. It highlights the challenges of building a multi-disciplinary and multi-institutional research collaboration that is attempting to create a treatment for... View Details
Keywords: Research and Development; Intellectual Property; Risk and Uncertainty; Strategic Planning; Collaborative Innovation and Invention; Health Disorders; Pharmaceutical Industry; Biotechnology Industry; Health Industry
Lakhani, Karim R., and Paul R. Carlile. "Myelin Repair Foundation: Accelerating Drug Discovery Through Collaboration." Harvard Business School Case 610-074, March 2010. (Revised May 2012.)
- February 2021 (Revised September 2022)
- Case
Marie Curie: Changing the World
By: Robert Simons and Shirley Sun
This case describes the rise of Marie Curie from a poor family in Poland to the pinnacle of scientific fame. The case describes how Curie, as a young woman interested in science, found a way to earn a doctorate at the Sorbonne and perform pathbreaking research on... View Details
Keywords: Legacy; Impact; Science; Research; Personal Characteristics; Mission and Purpose; Success; Work-Life Balance; Higher Education; Personal Development and Career
Simons, Robert, and Shirley Sun. "Marie Curie: Changing the World." Harvard Business School Case 121-059, February 2021. (Revised September 2022.)
- March 2006
- Case
The Whitesides Lab
By: H. Kent Bowen and Francesca Gino
A significant part of the long-term economic growth in developed economies depends on the translation of scientific research into new products and processes. Focuses on the front end of this value creation stream. The laboratory of George Whitesides has a 30-year... View Details
Keywords: Research; Performance Productivity; Economic Growth; Infrastructure; Creativity; Groups and Teams; Value Creation; Factories, Labs, and Plants; Leadership; Resource Allocation
Bowen, H. Kent, and Francesca Gino. "The Whitesides Lab." Harvard Business School Case 606-064, March 2006.
- 2018
- Chapter
Competing Interests
By: Joel Goh
Book Abstract: The editors, aided by a team of internationally acclaimed experts, have curated this timely volume to help newcomers and seasoned researchers alike to rapidly comprehend a diverse set of thrusts and tools in this rapidly growing cross-disciplinary field.... View Details
Goh, Joel. "Competing Interests." Chap. 4 in Handbook of Healthcare Analytics: Theoretical Minimum for Conducting 21st Century Research on Healthcare Operations, edited by Tinglong Dai and Sridhar Tayur, 51–78. John Wiley & Sons, 2018.
- 06 Feb 2012
- Research & Ideas
Kodak: A Parable of American Competitiveness
high-tech products could only be found in the United States. These successes were due in large part to government investment in basic science research and mass production. "During World War II, the American public believed science... View Details