Publications

17 Sep 2024
HBS Case

The Climate Targets Leaders Need to Know as Regulations Loom

Michael Toffel, the Senator John Heinz Professor of Environmental Management at Harvard Business School. Roughly 42 percent of Fortune 500 companies said they’d reached an environmental target or committed to reaching one by 2030, an 11... View Details

Keywords: by Rachel Layne

31 May 2016
HBS Case

Who Owns Space?

New Space sector: namely, to use it as a means of launching classroom discussion and research on the subtleties and challenges of the relationship between the public and private sectors. An associate professor of business administration... View Details

Keywords: Re: Matthew C. Weinzierl; Aerospace

2022
Chapter

Sustainability Science and Corporate Cleanup in Community Fields: The Translation, Resistance and Integration Process Model

By: P. Devereaux Jennings, Maggie Cascadden and Andrew J. Hoffman

Both practically and theoretically, the sustainability science and corporate operation perspectives often diverge. Overcoming this divergence requires some degree of engagement with organizational field members; not just negotiation, but on-the-ground process work to... View Details

Keywords: Environmental Sustainability; Business Processes; Science-Based Business; Research

2017
Mimeo

Science for Society: Science and Technology Based Social Entrepreneurship

By: Tarun Khanna, Shashank Shah and Kundan Madireddy

This publication is an outcome of the team's research, engagement and interactions with over 25 science and technology-based social enterprises in India. It provides details on the research process, insightful outcomes and innovative impact.
Throughout the... View Details

Keywords: Social Entrepreneurship; Science-Based Business; Information Technology; Business and Community Relations; India

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November 2014
Teaching Note

Houston We Have a Problem: NASA and Open Innovation (A) and (B)

By: Michael L. Tushman, Hila Lifshitz-Assaf and Kerry Herman

Keywords: Leading Change; Innovation Leadership; Science-Based Business

November 1983 (Revised May 1984)
Case

SSS (Scientific Systems Services)

By: Howard H. Stevenson and Michael J. Roberts

Keywords: Science-Based Business

1999
Chapter

The Pharmaceutical Industry and the Revolution in Molecular Biology: Interactions Among Scientific, Institutional, and Organizational Change

By: Rebecca Henderson, Gary P. Pisano and Luigi Orsenigo

Keywords: Science-Based Business; Organizational Change and Adaptation; Transformation; Pharmaceutical Industry

December 2008 (Revised January 2011)
Case

Arcadia Biosciences: Seeds of Change

By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman

Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details

Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China; India; California

1992
Chapter

Issues of Participation and Rights Allocation in Tradeable Permits Systems to Reduce Greenhouse Gas Emissions

By: James K. Sebenius and Michael Grubb

Keywords: Corporate Social Responsibility and Impact; Climate Change; Pollutants; Science-Based Business

February 2008 (Revised August 2008)
Case

EXACT Sciences Corp.: Commercializing a Diagnostic Test

By: Regina E. Herzlinger

This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details

Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry

2001
Chapter

Transforming Life, Transforming Business: The Life Science Revolution

By: Juan Enriquez and Ray A. Goldberg

Keywords: Science-Based Business; Organizational Change and Adaptation; Human Needs; Welfare; Transformation

18 Apr 2019
Research & Ideas

Open Innovation Contestants Build AI-Based Cancer Tool

article, “Use of Crowd Innovation to Develop an Artificial Intelligence-Based Solution for Radiation Therapy Targeting,” is co-authored by Harvard Business School Professor Karim R. Lakhani and seven colleagues with expertise in radiation... View Details

Keywords: by Martha Lagace; Health; Medical Devices & Supplies

2010
Working Paper

From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science

This paper examines gender differences in the participation of university life science faculty in commercial science. Based on theory and field interviews, we develop hypotheses regarding how scientists' productivity, co-authorship networks, and institutional... View Details

Keywords: Business Startups; For-Profit Firms; Gender Characteristics; Higher Education; Entrepreneurship; Governing and Advisory Boards; Science-Based Business; Nonprofit Organizations; Biotechnology Industry

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December 2023 (Revised March 2024)
Case

Manufacturing Moderna's Future

By: Satish Tadikonda and William Marks

In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details

Keywords: Health Pandemics; Health Testing and Trials; Technological Innovation; Product Development; Production; Science-Based Business; Biotechnology Industry

2001
Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn

U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details

Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry

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June 2011 (Revised October 2013)
Case

Gene Patents (A)

By: Richard Hamermesh, David Kiron and Phillip Andrews

In March 2010, U.S. District Court Judge Robert Sweet overturned 30 years of legal precedent and ruled that unaltered human genes could not be patented. This case reviews patent law and how it relates to our increasing knowledge of the Human Genome. The case issues... View Details

Keywords: Courts and Trials; Patents; Genetics; Judgments; Science-Based Business; Biotechnology Industry; United States

June 2019
Teaching Note

Zebra Medical Vision

By: Shane Greenstein and Sarah Gulick

Teaching note is meant to accompany Zebra Medical Vision case, which offers a look at a company’s decisions as a small startup competing with other startups and major technology companies. It also demonstrates the challenges faced by a machine learning company working... View Details

Keywords: Business Startups; Science-Based Business; Applications and Software; Patents; Cross-Cultural and Cross-Border Issues; Health Care and Treatment; Health Industry; Medical Devices and Supplies Industry; Technology Industry; Israel

October 2012
Teaching Plan

Vertex Pharmaceuticals and the Cystic Fibrosis Foundation: Venture Philanthropy Funding for Biotech (TP)

By: Robert F. Higgins

This is the teaching note related to HBS case 808005. In 2001, Vertex Pharmaceuticals Incorporated acquired the San Diego-based biotech company, Aurora Biosciences. The combination of Vertex's and Aurora's technologies would improve the flow of novel drug candidates... View Details

Keywords: Venture Philanthropy; Biotechnology; Funding Philanthropy Venture; Cystic Fibrosis; Foundations; Pharmaceuticals; Mergers and Acquisitions; For-Profit Firms; Venture Capital; Philanthropy and Charitable Giving; Science-Based Business; Nonprofit Organizations; Pharmaceutical Industry; Biotechnology Industry; United States; San Diego