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October 2012
Case

GSK's Acquisition of Sirtris: Independence or Integration? (Abridged)

By: Toby Stuart and James Weber

An executive from pharmaceutical company GSK must choose how much to integrate a recently acquired biotechnology firm, Sirtris. Moncef Slaoui, GSK's global head of R&D, championed the acquisition of Sirtris to gain access to its potentially revolutionary science.... View Details

Keywords: Mergers and Acquisitions; Resource Allocation; Organizational Change and Adaptation; Organizational Culture; Organizational Structure; Research and Development; Science-Based Business; Integration

2022
Chapter

Sustainability Science and Corporate Cleanup in Community Fields: The Translation, Resistance and Integration Process Model

By: P. Devereaux Jennings, Maggie Cascadden and Andrew J. Hoffman

Both practically and theoretically, the sustainability science and corporate operation perspectives often diverge. Overcoming this divergence requires some degree of engagement with organizational field members; not just negotiation, but on-the-ground process work to... View Details

Keywords: Environmental Sustainability; Business Processes; Science-Based Business; Research

2017
Mimeo

Science for Society: Science and Technology Based Social Entrepreneurship

By: Tarun Khanna, Shashank Shah and Kundan Madireddy

This publication is an outcome of the team's research, engagement and interactions with over 25 science and technology-based social enterprises in India. It provides details on the research process, insightful outcomes and innovative impact.
Throughout the... View Details

Keywords: Social Entrepreneurship; Science-Based Business; Information Technology; Business and Community Relations; India

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November 2014
Teaching Note

Houston We Have a Problem: NASA and Open Innovation (A) and (B)

By: Michael L. Tushman, Hila Lifshitz-Assaf and Kerry Herman

Keywords: Leading Change; Innovation Leadership; Science-Based Business

December 2008 (Revised January 2011)
Case

Arcadia Biosciences: Seeds of Change

By: Arthur A. Daemmrich, Forest L. Reinhardt and Mary Louise Shelman

Arcadia Biosciences is an entrepreneurial California agricultural biotech company seeking to earn carbon credits by modifying commodity crops for use in China and India. Eric Rey, Arcadia's CEO, faced a strategic inflection point in early September 2008. The company... View Details

Keywords: Business Startups; Entrepreneurship; Growth and Development Strategy; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Biotechnology Industry; China; India; California

1992
Chapter

Issues of Participation and Rights Allocation in Tradeable Permits Systems to Reduce Greenhouse Gas Emissions

By: James K. Sebenius and Michael Grubb

Keywords: Corporate Social Responsibility and Impact; Climate Change; Pollutants; Science-Based Business

November 2023 (Revised March 2024)
Case

Infarm: Betting the (Indoor) Farm on Food Security

In the summer of 2023, the co-founders of Infarm, a controlled environment agriculture (CEA) company, were contemplating a major pivot going forward. While Infarm had successfully shown it could grow over 75 products—mainly herbs, leafy greens and mushrooms—in modular... View Details

Keywords: Plant-Based Agribusiness; Business Model; Market Entry and Exit; Science-Based Business; Business Strategy; Transition; Agriculture and Agribusiness Industry; Europe; North America; Toronto; Northeastern United States

December 2023 (Revised March 2024)
Case

Manufacturing Moderna's Future

By: Satish Tadikonda and William Marks

In 2019, Moderna faced long odds of survival having failed to develop a successful clinical program out of the vast platform technology they had built around mRNA. Nearly overnight, the company skyrocketed to success with a vaccine for COVID-19, leading to an extremely... View Details

Keywords: Health Pandemics; Health Testing and Trials; Technological Innovation; Product Development; Production; Science-Based Business; Biotechnology Industry

31 May 2016
HBS Case

Who Owns Space?

New Space sector: namely, to use it as a means of launching classroom discussion and research on the subtleties and challenges of the relationship between the public and private sectors. An associate professor of business administration... View Details

Keywords: Re: Matthew C. Weinzierl; Aerospace

June 2010 (Revised May 2017)
Teaching Note

Sydney IVF: Stem Cell Research

By: Robert Simons and Kathryn Rosenberg

Teaching Note for 109017. View Details

Keywords: Strategy And Execution; Management Control Systems; Levers Of Control; Strategy; Risk Management; Decisions; Cooperative Ownership; Product Development; Moral Sensibility; Governing Rules, Regulations, and Reforms; Expansion; Science-Based Business; Research; Management Practices and Processes; Business Subsidiaries; Biotechnology Industry; Sydney

November 2019 (Revised June 2020)
Case

Indigo Agriculture: Harnessing Nature

By: Marco Iansiti, Michael W. Toffel and James Barnett

Indigo Agriculture used a digital-enabled research and development (R&D) process to launch its initial product, microbial coatings for agricultural seeds, which increase crop yields while reducing the need for fertilizers. In doing so, the company developed direct... View Details

Keywords: Carbon Sequestration; Operations; Supply Chain; Social Enterprise; Product Development; Distribution Channels; Business Strategy; Digital Platforms; Environmental Sustainability; Science-Based Business; Climate Change; Agriculture and Agribusiness Industry; Green Technology Industry; United States; Massachusetts

November 1983 (Revised May 1984)
Case

SSS (Scientific Systems Services)

By: Howard H. Stevenson and Michael J. Roberts

Keywords: Science-Based Business

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30 Nov 2018
What Do You Think?

What’s the Best Administrative Approach to Climate Change?

Summing Up: Should a 'Montreal Protocol' for Administering Global Warming Be Pursued? Climate change and how to manage it is a daunting subject. Nevertheless, several readers of this month’s column were willing to venture a model or two for administering a system... View Details

Keywords: by James Heskett; Energy

September 1993 (Revised October 1994)
Case

Environment and International Trade

By: Forest L. Reinhardt

During the 1990s, environmental activists became interested in trade issues for the first time. Whereas GATT, the General Agreement on Tariffs and Trade, had previously been the province of trade specialists, a new poster popular among environmentalists depicted the... View Details

Keywords: Trade; Environmental Sustainability; Science-Based Business; Policy; Government and Politics; Agreements and Arrangements; Alliances; Globalization; International Relations; Conflict of Interests

September 2023 (Revised March 2024)
Case

ReMo Energy: Sizing Up Investors

By: Jeffrey J. Bussgang and Tom Quinn

In 2023, executives with ReMo Energy (founded 2020) were deciding which size ammonia plant to build as their first project. Their innovative model produced ammonia—useful for making fertilizer and for energy storage—from renewable energy, and they had received funding... View Details

12 Oct 2006
First Look

First Look: October 12, 2006

prescriptions for companies, investors, and policymakers seeking ways to improve the industry's performance. According to Pisano, the biotech industry's problems stem from its special character as a science-based business. This character... View Details

Keywords: Sean Silverthorne

August 2023 (Revised January 2024)
Supplement

Arla Foods: Data-Driven Decarbonization (A)

By: Michael Parzen, Michael W. Toffel, Amram Migdal and Susan Pinckney

Arla implemented a data-based price incentive system to measure, track, and influence climate friendly changes to reduce CO2 emissions across the world’s fourth largest dairy cooperative. View Details

Keywords: Dairy Industry; Business Earnings; Earnings Management; Environmental Accounting; Agribusiness; Animal-Based Agribusiness; Acquisition; Mergers and Acquisitions; Decision Making; Decisions; Voting; Environmental Management; Climate Change; Environmental Regulation; Environmental Sustainability; Green Technology; Pollution; Moral Sensibility; Values and Beliefs; Financial Strategy; Price; Profit; Revenue; Food; Geopolitical Units; Global Strategy; Ownership Type; Cooperative Ownership; Performance Efficiency; Performance Evaluation; Problems and Challenges; Natural Environment; Science-Based Business; Business Strategy; Commercialization; Cooperation; Corporate Strategy; Food and Beverage Industry; Agriculture and Agribusiness Industry; Europe; United Kingdom; European Union; Germany; Denmark; Sweden; Luxembourg; Belgium

20 Apr 2010
First Look

First Look: April 20

invisible hand of markets increasingly governs them. An assessment of this form of governance against the requirements of science-based businesses suggests a gap and a need for organizational innovation.... View Details

Keywords: Martha Lagace

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

May 2008
Case

Sensors Unlimited: Bringing InGaAs Technology to the Market

By: Willy C. Shih

Sensors Unlimited was a small start-up in short-wavelength infrared imaging. Its learning base came out of Bell Labs, RCA's Sarnoff Lab, and the Rockwell Science Center, and as it built its capabilities and ventured into new application areas, it discovered a “killer... View Details

Keywords: Applied Optics; Mergers and Acquisitions; Business Startups; Growth and Development Strategy; Science-Based Business; Commercialization; Aerospace Industry; Technology Industry

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