Publications

2025
Working Paper

Bringing Science to Market: Knowledge Foundations, Inventor-Founders, and Performance

By: Justine Boudou and Maria Roche

In this paper, we examine how a startup’s knowledge foundations—embedded in its core technology—influence its performance in the exit market. Using a dataset of 1,006 biomedicine startups founded between 2005 and 2015, we focus on two key factors: (1) the degree of... View Details

Keywords: Firm Performance; Knowledge Foundations; Exits; Academic Startups; Inventor-founder; Specialized Scientific Knowledge; Competitive Advantage; Value Creation; Research; Information Publishing; Business Startups; Entrepreneurship

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April 2023
Technical Note

An Art & A Science: How to Apply Design Thinking to Data Science Challenges

By: Michael Parzen, Eddie Lin, Douglas Ng and Jessie Li

We hear it all the time as managers: “what is the data that backs up your decisions?” Even local mom-and-pop shops now have access to complex point-of-sale systems that can closely track sales and customer data. Social media influencers have turned into seven-figure... View Details

Keywords: Decision Making; Framework; Analytics and Data Science

27 Aug 2008
Research & Ideas

Creating Leaders for Science-Based Businesses

other business practitioners. Much of the science discussed will unfold in the Allston complex's four buildings, which will house Harvard's initiatives in stem cells, bio-inspired engineering, systems... View Details

Keywords: by Garry Emmons; Biotechnology; Health

2017
Working Paper

Business and Sustainability: New Business History Perspectives

By: Ann-Kristin Bergquist

This working paper provides a long-term business history perspective on environmental sustainability. For a long time, the central issues addressed in the discipline of business history concerned how business enterprises innovated and created wealth, as well as... View Details

Keywords: Environmental Sustainability; Business History; Perspective

SSRN

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March 2011 (Revised June 2012)
Case

Office of Technology Transfer - Shanghai Institutes for Biological Sciences

By: Willy Shih, Sen Chai, Kamen Bliznashki and Courtney Hyland

Gordon Zong is trying to teach Chinese universities and research institutes how to do effective technology transfer and IP licensing, but he is trying to do it in an environment with weak property rights and an underdeveloped support infrastructure. As the managing... View Details

Keywords: Multinational Firms and Management; Patents; Knowledge Management; Law Enforcement; Business and Government Relations; Research and Development; Biotechnology Industry; Pharmaceutical Industry; China

19 Sep 2016
Research & Ideas

Why Isn't Business Research More Relevant to Business Practitioners?

Like many business leaders, Donovan Neale-May routinely seeks out information on business innovation and management trends. He reads reports from market analysis firms, white papers from companies in his... View Details

Keywords: by Carmen Nobel; Education

26 Jun 2009
Research Event

Business Summit: Business and the Environment

Editor's Note: This is a summary of an HBS Business Summit presentation. View a full summary and video of the event on the HBS Centennial Web site linked below. Date of Event: October 13, 2008 Moderator: Forest Reinhardt, HBS faculty... View Details

Keywords: Re: Forest L. Reinhardt; Energy; Utilities

March 2008
Case

Novartis AG: Science-Based Business

By: H. Kent Bowen and Courtney Purrington

Novartis is a science-based drug company, which has important implications for its business strategy. It is one of the largest pharmaceutical companies in the world with over $38B in sales in 2007. Pharmaceuticals account for slightly over $24B of that total. In 2007,... View Details

Keywords: Innovation and Invention; Resource Allocation; Product Development; Partners and Partnerships; Research and Development; Science-Based Business; Pharmaceutical Industry

May 2017
Teaching Plan

Neurotrack and the Alzheimer's Puzzle

By: Richard G. Hamermesh and Carin-Isabel Knoop

Teaching Note for HBS No. 816-072. View Details

Keywords: Health Care; Alzheimer's Disease; Career Path; Life Science Business

2025
Working Paper

Data-driven Technologies and Local Information Advantages in Small Business Lending

By: Wilbur Chen, Jung Koo Kang and Aditya Mohan

We investigate whether banks' adoption of data-driven technologies influences competitive dynamics in local small business lending by diminishing the information advantages traditionally held by local banks. Using local newspaper closures as an adverse shock to the... View Details

Keywords: Data-driven Technologies; Local Information Advantages; Local Banks; Relationship Lending; Small Business Loans; Small Business; Local Range; Financing and Loans; Banks and Banking; Analytics and Data Science; Banking Industry

SSRN

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19 Oct 2015
Research & Ideas

Business Research that Makes for Smarter Public Policy

Academic business research typically travels one-way. From government agencies, scholars gather and process data—say on workplace safety or environmental pollution—perform analysis, and publish the results. Rarely, however, do they take... View Details

Keywords: by Michael Blanding

03 Jan 2017
Research & Ideas

5 New Year's Resolutions You Can Keep (With the Help of Behavioral Science Research)

conduct sociological and psychological studies to get a true handle on what motivates people to do what they do—and what motivates them to do better. With that, we share some well-researched tips—based on the findings of behavioral economists at Harvard View Details

Keywords: by Carmen Nobel

August 2017 (Revised December 2018)
Case

Tamarin App: Natural Language Processing

By: Srikant M. Datar and Caitlin N. Bowler

In this case, students explore the challenges of using sentiment analysis to monitor and understand public perception around a software application, Tamarin SEO App. Technical topics include building a filtering classifier using naive Bayes and sentiment analysis This... View Details

Keywords: Data Science; Branding; Data Analytics; Analytics and Data Science; Brands and Branding; Analysis; Perception; Planning

August 2017 (Revised August 2018)
Case

The Oakland Athletics: Strategy & Metrics for a Budget

By: Srikant M. Datar and Caitlin N. Bowler

This case considers Oakland Athletics General Manager Billy Beane’s data driven and, in baseball circles unconventional, approach to winning games over the duration of the long Major League Baseball season. Beane’s critical approach to crafting strategy within his... View Details

Keywords: Data Analysis; Metrics; Data Science; Analytics and Data Science; Analysis; Measurement and Metrics; Competitive Strategy; Organizational Culture; Sports Industry

30 Jun 2021
In Practice

The Harvard Business School Faculty Summer Reader 2021

years—so one can keep hoping! Karim Lakhani (@klakhani) is the Dorothy & Michael Hintze Professor of Business Administration and co-director of the Laboratory for Innovation Science at Harvard. George... View Details

Keywords: by Kathryn Haviland

March 2019
Case

Investing in the Future: Corning Inc. and the Alternative School for Math and Science

By: Derek van Bever and Miho Kubagawa

In early 2017, Kim Frock (MBA 1987), founder and administrative head of school for the Alternative School for Math and Science (ASMS) in Corning, New York, is beginning to think through the issue of leadership succession at the school. Founded in close partnership with... View Details

Keywords: Middle School Education; Leadership; Management Succession; Partners and Partnerships; Business and Community Relations

April 1993 (Revised December 2001)
Case

General Dynamics and Computer Sciences Corporation: Outsourcing the IS Function (B)

By: F. Warren McFarlan and Katherine Seger

Designed to look at outsourcing from the perspective of a major computer services company trying to get into the business. View Details

Keywords: Communication Technology; Business Startups; Business Plan; Business Strategy; Job Cuts and Outsourcing; Financial Management; Management Teams; Communication Strategy; Organizational Design; Product Design; Accounting; Activity Based Costing and Management; Computer Industry; Information Technology Industry

April 1993 (Revised May 1994)
Case

General Dynamics and Computer Sciences Corporation: Outsourcing the IS Function (A)

By: F. Warren McFarlan and Katherine Seger

Designed to generate discussion on the issues of outsourcing from the perspective of a firm thinking about turning over its IS activities to a third-party vendor. View Details

Keywords: Management Systems; Management Style; Information Technology; Job Cuts and Outsourcing; Business Strategy; Economic Systems; Business or Company Management; Organizational Change and Adaptation; Business Processes; Employment; Emerging Markets; Activity Based Costing and Management; Information Technology Industry; Consulting Industry

June 2012
Article

A Reexamination of Tunneling and Business Groups: New Data and New Methods

By: Jordan I. Siegel and Prithwiraj Choudhury

One of the most rigorous methodologies in the corporate governance literature uses firms' reactions to industry shocks to characterize the quality of governance. This methodology can produce the wrong answer unless one considers the ways firms compete. Because... View Details

Keywords: Corporate Governance; Mergers And Acquisitions; Business Economics; Firm Organization; Firm Performance; Groups and Teams; Analytics and Data Science

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