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      • February 2024
      • Teaching Note

      Compass Pathways: Pioneering Psychedelic Treatment

      By: Tiona Zuzul
      Teaching Note for HBS Case No. 724-412. View Details
      Keywords: Commercialization; Corporate Strategy; Competitive Strategy; Product Launch; Health Care and Treatment; Pharmaceutical Industry; Europe; United States; United Kingdom
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      Zuzul, Tiona. "Compass Pathways: Pioneering Psychedelic Treatment." Harvard Business School Teaching Note 724-457, February 2024.
      • February 2024
      • Article

      Representation and Extrapolation: Evidence from Clinical Trials

      By: Marcella Alsan, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein and Heidi L. Williams
      This article examines the consequences and causes of low enrollment of Black patients in clinical trials. We develop a simple model of similarity-based extrapolation that predicts that evidence is more relevant for decision-making by physicians and patients when it... View Details
      Keywords: Representation; Racial Disparity; Health Testing and Trials; Race; Equality and Inequality; Innovation and Invention; Pharmaceutical Industry
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      Alsan, Marcella, Maya Durvasula, Harsh Gupta, Joshua Schwartzstein, and Heidi L. Williams. "Representation and Extrapolation: Evidence from Clinical Trials." Quarterly Journal of Economics 139, no. 1 (February 2024): 575–635.
      • February 1, 2024
      • Editorial

      Retired Military Officials: Protecting Abortion Care Keeps America Safe

      By: Louis Caldera, Ray Mabus and Deborah James
      Keywords: Military; Health Care and Treatment; Gender; Recruitment; National Security
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      Caldera, Louis, Ray Mabus, and Deborah James. "Retired Military Officials: Protecting Abortion Care Keeps America Safe." Washingtonpost.com (February 1, 2024).
      • January 2024
      • Supplement

      Buurtzorg

      By: Ethan Bernstein and Tatiana Sandino
      As co-founders of home nursing company Buurtzorg, Jos de Blok and Gonnie Kronenberg prized both self-management and organizational learning. Buurtzorg’s 10,000 nurses across 950 neighborhood nursing teams in the Netherlands were empowered to manage themselves, both in... View Details
      Keywords: Organizational Design; Management Style; Business Model; Knowledge Dissemination; Learning; Organizational Culture; Health Industry; Netherlands
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      Bernstein, Ethan, and Tatiana Sandino. "Buurtzorg." Harvard Business School Multimedia/Video Supplement 424-705, January 2024.
      • January 19, 2024
      • Article

      Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder

      By: Robert S. Kaplan and Sarah E. Wakeman
      U.S. overdose deaths currently exceed 100,000 per year. New facilities, known as bridge clinics, are broadening access to high-quality care by offering outpatient substance use disorder (SUD) treatment with few access barriers. But many of the critical services offered... View Details
      Keywords: Health Care and Treatment; Cost; Adoption
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      Kaplan, Robert S., and Sarah E. Wakeman. "Value-Based Health Care Can Transform the Treatment of Patients with Substance Use Disorder." Health Affairs Forefront (January 19, 2024).
      • January 2024 (Revised April 2024)
      • Teaching Note

      Somatus: Value-Based Kidney Care (A) & (B)

      By: Ariel D. Stern, Robert S. Huckman and Sarah Mehta
      This teaching note accompanies case no. 622-009 and 622-045 (Somatus: Value-Based Kidney Care, A and B). View Details
      Keywords: Business Startups; Disruption; Entrepreneurship; Health Care and Treatment; Health Disorders; Medical Specialties; Innovation and Invention; Disruptive Innovation; Management; Business Strategy; Value Creation; Health Industry; United States; Virginia
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      Stern, Ariel D., Robert S. Huckman, and Sarah Mehta. "Somatus: Value-Based Kidney Care (A) & (B)." Harvard Business School Teaching Note 624-013, January 2024. (Revised April 2024.)
      • January 2024
      • Background Note

      Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?

      By: Regina E. Herzlinger and James Wallace
      How can we evaluate if innovative health care ventures can do good—benefit society—and do well—become financially viable? This question is the topic of the first module in the Innovating in Health Care course book.

      This note and "Health Stop (A): What Type... View Details
      Keywords: Business Model; Health Care and Treatment; Collaborative Innovation and Invention; Mission and Purpose; Alignment; Health Industry
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      Herzlinger, Regina E., and James Wallace. "Evaluating Innovations in the Organization of Primary Care: What Type of Innovation Is It and How Well Does It Align with the Six Factors?" Harvard Business School Background Note 324-037, January 2024.
      • January 2024
      • Article

      A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder

      By: Sarah E. Wakeman, Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe and Robert S. Kaplan
      The US fee-for-service payment system under-reimburses clinics offering access to comprehensive treatments for opioid use disorder (OUD). The funding shortfall limits a clinic’s ability to expand and improve access, especially for socially marginalized patients with... View Details
      Keywords: Health Care and Treatment; Cost; Equality and Inequality; Health Industry
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      Wakeman, Sarah E., Elizabeth Powell, Syed Shehab, Grace Herman, Laura Kehoe, and Robert S. Kaplan. "A Cost Model for a Low Threshold Clinic Treating Opioid Use Disorder." Journal of Behavioral Health Services & Research 51, no. 1 (January 2024): 22–30.
      • January 2024
      • Article

      Cost of Exempting Sole Orphan Drugs from Medicare Negotiation

      By: Matthew Vogel, Olivia Zhao, William B. Feldman, Amitabh Chandra, Aaron S. Kesselheim and Benjamin N. Rome
      Importance: The Inflation Reduction Act (IRA) requires Medicare to negotiate prices for some high-spending drugs but exempts drugs approved solely for the treatment of a single rare disease.
      Objective: To estimate Medicare spending and global... View Details
      Keywords: Health Care and Treatment; Insurance; Price; Health Industry
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      Vogel, Matthew, Olivia Zhao, William B. Feldman, Amitabh Chandra, Aaron S. Kesselheim, and Benjamin N. Rome. "Cost of Exempting Sole Orphan Drugs from Medicare Negotiation." JAMA Internal Medicine 184, no. 1 (January 2024): 63–69.
      • January–February 2024
      • Article

      Shared Service Delivery Can Increase Client Engagement: A Study of Shared Medical Appointments

      By: Ryan W. Buell, Kamalini Ramdas, Nazlı Sönmez, Kavitha Srinivasan and Rengaraj Venkatesh
      Problem Definition: Clients and service providers alike often consider one-on-one service delivery to be ideal, assuming – perhaps unquestioningly – that devoting individualized attention best improves client outcomes. In contrast, in shared service delivery, clients... View Details
      Keywords: Health Care and Treatment; Customer Satisfaction; Outcome or Result; Performance Improvement
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      Buell, Ryan W., Kamalini Ramdas, Nazlı Sönmez, Kavitha Srinivasan, and Rengaraj Venkatesh. "Shared Service Delivery Can Increase Client Engagement: A Study of Shared Medical Appointments." Manufacturing & Service Operations Management 26, no. 1 (January–February 2024): 154–166.
      • December 2023 (Revised February 2024)
      • Case

      Transforming Healthcare Delivery at Karolinska University Hospital

      By: Susanna Gallani, Mary Witkowski, Elena Corsi and Nikolina Jonsson
      The case study examines the journey toward value-based healthcare at Karolinska University Hospital. The hospital's ambitious shift to a patient-centered care delivery model, accompanied by the construction of a new facility, encountered challenges such as high costs,... View Details
      Keywords: Change Management; Transformation; Transition; Business Organization; Communication Strategy; Information Infrastructure; Service Delivery; Organizational Change and Adaptation; Organizational Structure; Health Industry; Sweden; Europe
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      Gallani, Susanna, Mary Witkowski, Elena Corsi, and Nikolina Jonsson. "Transforming Healthcare Delivery at Karolinska University Hospital." Harvard Business School Case 124-070, December 2023. (Revised February 2024.)
      • December 2023
      • Teaching Note

      Buurtzorg

      By: Ethan Bernstein and Tatiana Sandino
      Teaching Note for HBS Case No. 122-101. As co-founders of home nursing company Buurtzorg, Jos de Blok and Gonnie Kronenberg prized both self-management and organizational learning. Buurtzorg’s 10,000 nurses across 950 neighborhood nursing teams in the Netherlands were... View Details
      Keywords: Health Care and Treatment; Employee Relationship Management; Knowledge Dissemination; Knowledge Management; Management Practices and Processes; Organizational Design; Organizational Structure; Groups and Teams; Learning; Health Industry; Netherlands
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      Bernstein, Ethan, and Tatiana Sandino. "Buurtzorg." Harvard Business School Teaching Note 124-059, December 2023.
      • December 12, 2023
      • Article

      Prices for Common Services at Quaternary vs Nonquaternary Hospitals

      By: Brandon W. Yan, Maximilian J. Pany and Leemore S. Dafny
      Using commercial health insurance claims data from 2017-2019, we assessed whether quaternary hospitals charged higher prices for common, unspecialized services also offered by nonquaternary hospitals. We found quaternary-hospital price premiums of 8.2 percent, on... View Details
      Keywords: Price; Health Care and Treatment; Insurance; Markets; Health Industry
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      Yan, Brandon W., Maximilian J. Pany, and Leemore S. Dafny. "Prices for Common Services at Quaternary vs Nonquaternary Hospitals." JAMA, the Journal of the American Medical Association 330, no. 22 (December 12, 2023): 2211–2213.
      • December 4, 2023
      • Comment

      The Great Resignation, Employment, and Wages in Health Care

      By: Amitabh Chandra and Louis-Jonas Heizlsperger
      Notwithstanding concerns about staffing levels and burnout in health care, federal wage and employment data does not support the suggestion that a COVID-19 pandemic-related spike in quitting has had an enduring impact for hospitals or physician offices. Employment in... View Details
      Keywords: Resignation and Termination; Employment; Wages; Health Industry
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      Chandra, Amitabh, and Louis-Jonas Heizlsperger. "The Great Resignation, Employment, and Wages in Health Care." NEJM Catalyst (December 4, 2023).
      • December 2023
      • Article

      Association of Hospital System Affiliation with COVID-19 Capacity Burden

      By: Zachary Levin, Pinar Karaca-Mandic, Richard J. Boxer and Regina E. Herzlinger
      What is the message? The COVID-19 pandemic exposed the highly variable and uncoordinated responses by hospitals. The authors found that while the non-top ten system affiliated hospitals had a larger COVID-19 share index relative to independent hospitals, top-ten system... View Details
      Keywords: COVID-19 Pandemic; Resource Allocation; Health Pandemics; Demographics; Health Care and Treatment; Health Industry
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      Levin, Zachary, Pinar Karaca-Mandic, Richard J. Boxer, and Regina E. Herzlinger. "Association of Hospital System Affiliation with COVID-19 Capacity Burden." Health Management, Policy and Innovation 8, no. 3 (December 2023).
      • 2025
      • Working Paper

      Healthcare Provider Bankruptcies

      By: Samuel Antill, Ashvin Gandhi, Jessica Bai and Adrienne Sabety
      Healthcare firms are filing for Chapter 11 bankruptcy at record rates. We find that bankruptcies increase healthcare staff turnover, worsen care, and harm patients. Using a difference-in-differences design, we estimate that a bankruptcy filing immediately increases... View Details
      Keywords: Insolvency and Bankruptcy; Health Care and Treatment; Outcome or Result; Retention; Health Industry
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      Antill, Samuel, Ashvin Gandhi, Jessica Bai, and Adrienne Sabety. "Healthcare Provider Bankruptcies." Working Paper, April 2025.
      • October 2023
      • Supplement

      Hey Jane: Background on Abortion in the U.S.

      By: Rembrand Koning, Geraldine Pena-Galea and Sarah Mehta
      Keywords: Health Care and Treatment; Health Industry; United States
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      Koning, Rembrand, Geraldine Pena-Galea, and Sarah Mehta. "Hey Jane: Background on Abortion in the U.S." Harvard Business School Supplement 724-390, October 2023.
      • October 2023
      • Case

      Hey Jane: Delivering Abortion Pills to the Doorstep

      By: Rembrand Koning, Geraldine Pena-Galea and Sarah Mehta
      This case tells the story of Hey Jane, a telehealth clinic founded in 2020 that provides virtual medication abortion services to eligible patients in nine U.S. states. By January 2023, the company had served more than 20,000 patients and raised nearly $10 million in... View Details
      Keywords: Operations; Business Startups; Health Care and Treatment; Growth and Development Strategy; Health Industry; Health Industry; United States
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      Koning, Rembrand, Geraldine Pena-Galea, and Sarah Mehta. "Hey Jane: Delivering Abortion Pills to the Doorstep." Harvard Business School Case 724-408, October 2023.
      • October 2023
      • Supplement

      Hey Jane: Early Investor Pitch Deck

      By: Rembrand Koning
      Keywords: Health Care and Treatment; Operations; Entrepreneurial Finance; Health Industry; Health Industry; United States
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      Koning, Rembrand. "Hey Jane: Early Investor Pitch Deck." Harvard Business School Supplement 724-409, October 2023.
      • October 2023
      • Background Note

      What Leaders Need to Know about Mental Health

      By: Boris Groysberg, Robin Abrahams, Liana Groysberg, Natalia Groysberg and Abhijit Naik
      This paper will provide an overview of the nature of anxiety and depression, the particular vulnerabilities and stresses of CEOs, and suggestions for managing mental health in the workplace. View Details
      Keywords: CEO; Mental Health; Health Care and Treatment; Health Disorders; Leadership; Well-being
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      Groysberg, Boris, Robin Abrahams, Liana Groysberg, Natalia Groysberg, and Abhijit Naik. "What Leaders Need to Know about Mental Health." Harvard Business School Background Note 424-032, October 2023.
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