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October 2012
Supplement

Aqua Bounty Courseware

By: Lucy White and Steve Burn-Murdoch

Valuation of a pre-revenue biotech company at IPO using probability trees and real option techniques. Company is based in Massachusetts and lists in London on AIM. Products are genetically-modified fast-growing salmon for fish farmers and disease-prevention drugs and... View Details

Keywords: IPO; Valuation; Real Options; Decision Tree; Biotech; Genetically Modified; Salmon; Entrepreneurship; Finance; Agriculture and Agribusiness Industry; Biotechnology Industry; North and Central America; Europe; South America

December 2011
Case

Bergerac Systems: The Challenge of Backward Integration

By: David A. Garvin and Sunru Yong

Bergerac Systems is a small, rapidly growing manufacturer of diagnostic instruments used in veterinary practices. The company introduced the OmniVue chemistry analyzer, which enables veterinarians to run a wide range of blood and blood chemistry tests on their animal... View Details

Keywords: Financial Analysis; Manufacturing Strategy; Strategy; Production; Supply Chain Management; Vertical Integration; Performance Capacity; Financial Strategy; Medical Devices and Supplies Industry

September 2012 (Revised January 2014)
Case

Aqua Bounty

By: Lucy White and Stephen Burn-Murdoch

Valuation of a pre-revenue biotech company at IPO using probability trees and real option techniques. Company is based in Massachusetts and lists in London on AIM. Products are genetically-modified fast-growing salmon for fish farmers and disease-prevention drugs and... View Details

Keywords: IPO; Valuation; Real Options; Decision Tree; Biotech; Genetically Modified; Salmon; Entrepreneurship; Finance; Agriculture and Agribusiness Industry; Biotechnology Industry; North and Central America; Europe; South America

June 1996
Case

Becton Dickinson: Managing the Global Enterprise, 1996

Becton Dickinson, a U.S.-based maker of medical and diagnostic devices, has been organized into a mixed structure of U.S.-based divisions and country/region organizations. In 1995, three businesses shifted to become worldwide divisions, forcing a reexamination of the... View Details

Keywords: Organizational Change and Adaptation; Business or Company Management; Multinational Firms and Management; Organizational Structure; Medical Devices and Supplies Industry; United States

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April 2012
Article

How Many Direct Reports?

By: Gary L. Neilson and Julie Wulf

If senior executives are feeling ever more pressed for time, why would they add more to their plates? It might sound counterintuitive, but research by Booz & Company's Gary L. Neilson and me shows that over the past 20 years the CEO's average span of control, measured... View Details

Keywords: Leadership; Governance Controls; Managerial Roles; Adaptation; Personal Development and Career; Cooperation; Management Teams

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October 2023 (Revised June 2024)
Case

Revvity: A Symbol of Change

By: Satish Tadikonda and William Marks

After selling the PerkinElmer name and several ancillary business units, Prahlad Singh (CEO) and his team at the newly christened Revvity faced a challenge on how best to capitalize on the opportunities ahead for the business and emerge as winners within the Life... View Details

Keywords: Business Model; Organizational Change and Adaptation; Corporate Strategy

December 2020 (Revised April 2021)
Case

IBM Watson at MD Anderson Cancer Center

By: Shane Greenstein, Mel Martin and Sarkis Agaian

After discovering that their cancer diagnostic tool, designed to leverage the cloud computing power of IBM Watson, needed greater integration into the clinical processes at the MD Anderson Cancer Center, the development team had difficult choices to make. The Oncology... View Details

Keywords: Decision Making; Innovation Strategy; Knowledge Management; Knowledge Use and Leverage; Operations; Failure; Information Technology; Applications and Software; Health Care and Treatment; Product Development; Health Industry; Information Technology Industry; Technology Industry; United States; Houston; Texas

January 2014 (Revised June 2014)
Case

23andMe: Genetic Testing for Consumers (A)

By: John A. Quelch and Margaret L. Rodriguez

On November 22, 2013, the direct-to-consumer genetic testing provider, 23andMe, received a letter from the U.S. Food and Drug Administration (FDA) ordering the company to halt the sale and promotion of its genetic testing kit. The FDA stated that the product was... View Details

Keywords: Public Health; Genome Testing; Health Care; Ancestry; 23andMe; Marketing; Product Launch; Health; Health Care and Treatment; Health Testing and Trials; Genetics; Strategy; Health Industry; United States

2024
Working Paper

Gastrointestinal Endoscopy--Without Cutting In: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how endoscopy transformed the diagnosis of ulcers, cancerous polyps, and other alimentary canal diseases and enabled “minimally invasive” surgeries to treat such diseases. Specifically, we chronicle how: 1) flexible glass fiber endoscopes... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2024
Working Paper

Ultrasound Imaging--Cheap, Versatile, and Safe: Case Histories of Transformational Advances

By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins

This case history describes how efforts on multiple fronts, including advocacy, training, and technological development, made ultrasound the second most commonly used diagnostic imaging technology (after X-rays). Specifically, we chronicle 1) ultrasound’s development... View Details

Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms

2022
Report

Competitiveness Roadmap for India@100

By: Michael E. Porter and Christian H.M. Ketels

The Competitiveness Roadmap for India lays out policy principles to guide India's efforts to move towards middle-income and beyond over the next 25 years. It covers a discussion of appropriate outcome ambitions, the underlying development approach, specific policy... View Details

Keywords: Economic Growth; Strategy; Competition; Policy; Government Administration; India

June 2023 (Revised June 2023)
Supplement

Roche: ESG and Access to Healthcare

By: George Serafeim

In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details

October 2014 (Revised December 2018)
Background Note

Leading and Managing Change

By: Ryan Raffaelli

Managing change is consistently ranked as one of the most critical and difficult tasks that leaders face. This note outlines the key choices that leaders must make when engineering change. It is organized into four sections, offering guidance on how to 1) diagnose the... View Details

Keywords: Change Leadership; Leading Change; Change Management

May 2009 (Revised August 2013)
Case

The DiagnoFirst Opportunity

By: Robert C. Pozen and Rukmini Balu

John Mason, a principle at Oldwell Partners, was facing a decision of whether or not to invest in DiagnoFirst, a molecular diagnostics firm. DiagnoFirst's key product was a genetic test that identified a subset of prostate cancer patients with a high risk of clinical... View Details

Keywords: Genetic Engineering; Genetically Modified; Genomics; Venture Capital; Patents; Genetics; Decision Choices and Conditions; Laws and Statutes; Investment; Science-Based Business; Biotechnology Industry

April 2009 (Revised November 2012)
Case

Sermo, Inc.

By: Thomas R. Eisenmann and Lars Peter Christian Nielsen

Sermo operates the leading online professional network for physicians in the United States. Doctors use Sermo free of charge to post surveys regarding diagnostic and treatment concerns and to discuss these concerns, as well as challenges with managing their practices.... View Details

Keywords: Entrepreneurship; Health Care and Treatment; Knowledge Sharing; Two-Sided Platforms; Conflict and Resolution; Social and Collaborative Networks; United States

March 2023 (Revised March 2023)
Case

Roche: Innovation and Access to Healthcare

By: George Serafeim, Susanna Gallani and Benjamin Maletta

In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details

July–August 2011
Article

Putting Business Models Under the Microscope

By: K. Merchant, Tatiana Sandino and D. Huelsbeck

The article provides advice for financial managers on evaluating business models for corporate performance measurement. Emphasis is given to a study sponsored by the Chartered Institute of Management Accountants (CIMA) that examined the business model of a medical... View Details

Keywords: Business Model; Financial Management; Performance Evaluation

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January 2025 (Revised March 2025)
Case

Creating Value by Splitting Aster: Can One Minus One Equal Two?

By: V.G. Narayanan and Kairavi Dey

Aster DM Healthcare (Aster), founded by Dr. Azad Moopen in 1987, is a prominent healthcare conglomerate with operations spanning hospitals, clinics, retail pharmacies, and diagnostic centers across India and the GCC. After its 2018 listing on India’s National Stock... View Details

Keywords: Corporate Governance; Corporate Accountability; Leadership; Change Management; Mergers and Acquisitions; Restructuring; Negotiation; Valuation; Health Industry; Asia; India; Middle East; United Arab Emirates

2016
Chapter

Evaluating the Effects of Large Scale Health Interventions in Developing Countries: The Zambian Malaria Initiative

By: Nava Ashraf, Gunther Fink and David N. Weil

Since 2003, Zambia has been engaged in a large-scale, centrally coordinated national anti-Malaria campaign, which has become a model in sub-Saharan Africa. This paper aims at quantifying the individual and macro-level benefits of this campaign, which involved mass... View Details

Keywords: Programs; Health Pandemics; Developing Countries and Economies; Zambia

December 1998 (Revised March 1999)
Case

Disruptive Technology a Heartbeat Away: Ecton, Inc.

By: Clayton M. Christensen and Edward G Cape

Describes an innovating start-up company with a disruptive technology to the large, expensive echocardiography machines that leading cardiologists use to create images of heart functions for diagnostic purposes. Ecton's machine is small, cheap, portable, and can't... View Details

Keywords: Business Startups; Disruption; Machinery and Machining; Entrepreneurship; Innovation and Invention; Marketing; Product; Commercialization; Technology; Medical Devices and Supplies Industry

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