Publications

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October 2024
Article

Medicare Part D Protected-Class Policy Is Associated with Lower Drug Rebates

By: Pragya Kakani, Michael Anne Kyle, Amitabh Chandra and Luca Maini

Medicare Part D does not allow plans to exclude drugs in six protected classes from their formularies, which may limit plans’ ability to negotiate rebates and lead to higher spending. We estimated the association between protected-class status, US-level estimated... View Details

Keywords: Insurance; Health Care and Treatment; Governing Rules, Regulations, and Reforms; United States

March 2024
Article

Medicare Price Negotiation and Pharmaceutical Innovation Following the Inflation Reduction Act

By: Matthew Vogel, Pragya Kakani, Amitabh Chandra and Rena M. Conti

The Inflation Reduction Act (IRA) requires Medicare to negotiate lower prices for some medicines with high Medicare spending. Using historical data from public and proprietary sources to apply the IRA's negotiation criteria retrospectively, we identify all drugs that... View Details

Keywords: Policy; Government Legislation; Health Care and Treatment; Negotiation; Price; Pharmaceutical Industry

June 9, 2023
Article

A Radical Treatment for Insulin Pricing

By: Leemore S. Dafny

In 2021, the Food and Drug Administration (FDA) approved the first interchangeable biosimilar for long-acting insulin, which many hoped would be substantially cheaper than the reference branded product. I explain why prices have barely changed, and argue that a... View Details

Keywords: Biosimilars; Rebates; Pharmaceuticals; Health Care and Treatment; Price; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry; United States

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April 2018 (Revised September 2018)
Case

Impact Investing for Cancer

By: Richard G. Hamermesh and Matthew G. Preble

It is early 2018, and Emily Park, managing director of impact for the Abreu Family Office, is meeting the next day with Tomás and Maria Abreu to discuss the various ways in which the Abreus can allocate a planned $100 million to make a meaningful difference in cancer... View Details

Keywords: Impact Investing; Investment; Health Disorders; Philanthropy and Charitable Giving; Decision Choices and Conditions

Educators

2020
Working Paper

How Should U.S. Bank Regulators Respond to the COVID-19 Crisis?

By: Michael Blank, Samuel G. Hanson, Jeremy C. Stein and Adi Sunderam

Drawing on lessons from the 2007–2009 Global Financial Crisis (GFC) and a simple conceptual framework, we examine the response of U.S. bank regulators to the COVID-19 pandemic. We argue that the current regulatory strategy of “watchful waiting”—the same strategy that... View Details

Keywords: COVID-19; Bank Regulation; Recapitalization; Health Pandemics; Banks and Banking; Governing Rules, Regulations, and Reforms; Strategy; Risk Management; United States

15 Aug 2006
First Look

First Look: August 15, 2006

expect bankers to have been less central than in Mexico and, perhaps, the United States. Second, I test if the availability of financing alternatives, like a well-developed bond market in Brazil, reduced the average importance of... View Details

Keywords: Sean Silverthorne

06 Aug 2013
First Look

First Look: August 6

behavior are reduced (Study 5). Our results have important implications for models of ethical decision making, moral behavior, and self-regulatory theory. Publisher's link: http://www.francescagino.com August 2013 Journal of Finance The... View Details

Keywords: Anna Secino

28 Aug 2017
Research & Ideas

Should Industry Competitors Cooperate More to Solve World Problems?

example here. More business leaders in the health care sector recognize that industry actors that engage in egregious pricing of drugs bring all kinds of problems to the whole industry. Silverthorne: You note that companies by themselves... View Details

Keywords: by Sean Silverthorne; Financial Services; Manufacturing; Agriculture & Agribusiness; Mining

September 2011
Teaching Note

Tengion: Bringing Regenerative Medicine to Life (TN)

By: Elie Ofek and Natalie Kindred

Teaching Note for 510031. View Details

Keywords: Partners and Partnerships; Production; Marketing; Cash; Health Care and Treatment; Medical Specialties; Research and Development; Biotechnology Industry

20 Mar 2018
First Look

First Look at New Research and Ideas, March 20, 2018

link: https://www.hbs.edu/faculty/Pages/item.aspx?num=54267 February 6, 2018 Harvard Business Review What Could Amazon's Approach to Health Care Look Like? By: Huckman, Robert S. Abstract—No abstract available. Publisher's link:... View Details

Keywords: Sean Silverthorne

Forthcoming
Article

When Should Public Programs Be Privately Administered? Theory and Evidence from the Paycheck Protection Program

By: Alexander W. Bartik, Zoë Cullen, Edward L. Glaeser, Michael Luca, Christopher Stanton and Adi Sunderam

What happens when public resources are allocated by private companies whose objectives may be imperfectly aligned with policy goals? We study this question in the context of the Paycheck Protection Program (PPP), which relied on private banks to disburse aid to small... View Details

Keywords: Paycheck Protection Program; Targeting; Impact; Entrepreneurship; Health Pandemics; Small Business; Financing and Loans; Outcome or Result; United States

SSRN

2020
Working Paper

Venture Capitalists and COVID-19

By: Paul A. Gompers, Will Gornall, Steven N. Kaplan and Ilya A. Strebulaev

We survey over 1,000 institutional and corporate venture capitalists (VCs) at more than 900 different firms to learn how their decisions and investments have been affected by the COVID-19 pandemic. We compare their survey answers to those provided by a large sample of... View Details

Keywords: Venture Capital; Health Pandemics; Investment; Decision Making; Surveys

February 2024
Teaching Note

AB InBev: Brewing Up Forecasts during COVID-19

By: Mark Egan and C. Fritz Foley

Teaching Note for HBS Case No. 224-020. In July 2021, the CEO of AB InBev's European operations and his team strategized to position the company for success post-pandemic. As the world's largest beer company, boasting over 500 brands, revenue of $46 billion, and a... View Details

Keywords: Forecasting; Investor Relations; Beverage Industry; Corporate Finance; Decisions; Forecasting and Prediction; Health Pandemics; Analytics and Data Science; Digital Transformation; Crisis Management; Business Model; Food and Beverage Industry; United States; Europe

Article

Time-Driven Activity-Based Costing in Emergency Medicine

By: Robert S. Kaplan, Brian J. Yun, Anand M. Prabhakar, Jonathan Warsh, John Brennan, Kyle E. Dempsey and Ali S. Raja

Value in emergency medicine is determined by both patient-important outcomes and the costs associated with achieving them. However, measuring true costs is challenging. Without an understanding of costs, emergency department (ED) leaders will be unable to determine... View Details

Keywords: Time-Driven Activity-Based Costing; Emergency Room; Health Care and Treatment; Value; Cost Management; Activity Based Costing and Management

10 Mar 2015
First Look

First Look: March 10

Oasys Water: Balancing Strategic Partnerships & Financing Decisions Oasys Water had developed a proprietary water treatment technology based on an innovative forward osmosis process that could remove dissolved solids from water more... View Details

Keywords: Carmen Nobel

fall 1994
Article

Racing to Invest? The Dynamics of Competition in Ethical Drug Discovery

By: Rebecca M. Henderson and Ian Cockburn

Keywords: Investment; Competition; Ethics; Health

July 2002
Article

Asset Accumulation, Interdependence and Technological Change: Evidence from Pharmaceutical Drug Discovery

By: Stefan Thomke and Walter Kuemmerle

Keywords: Assets; Information Technology; Change; Health

March 1993
Supplement

Burroughs Wellcome and AZT (B)

By: Willis M. Emmons III

Describes Burroughs Wellcome's response to protests over the pricing of its AIDS drug AZT in September 1989. Also presents short-term reactions by government officials, AIDS activists, and investors to Burroughs Wellcome's strategy. View Details

Keywords: Ethics; Health Pandemics; Multinational Firms and Management; Price; Crime and Corruption; Risk and Uncertainty; Business Strategy; Business and Community Relations; Business and Government Relations; Business and Shareholder Relations; Pharmaceutical Industry