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  • 2022
  • Working Paper

Regulatory Incentives for Innovation: The FDA's Breakthrough Therapy Designation

By: Amitabh Chandra, Jennifer Kao, Kathleen Miller and Ariel D. Stern
Regulators of new products confront a tradeoff between speeding a new product to market and collecting additional product quality information. The FDA’s Breakthrough Therapy Designation (BTD) provides an opportunity to understand if a regulator can use new policy to... View Details
Keywords: Research and Development; Governing Rules, Regulations, and Reforms; Product Development
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    Roy D. Shapiro

    Roy D. Shapiro is the Philip Caldwell Professor of Business Administration at the Harvard University Graduate School of Business Administration.  He is currently the faculty co-chair of the School's Technology and Operations Management Unit... View Details

    • 30 Jun 2009
    • First Look

    First Look: June 30

    by both venture capital firms and venture capital-financed companies in three cities-San Francisco, Boston, and New York. We find that firms open new satellite offices based on the success rate of venture... View Details
    Keywords: Martha Lagace
    • May 2025 (Revised May 2025)
    • Case

    Humana Commits to Value-Based Care

    By: V.G. Narayanan, Henry Eyring and David Lane
    In late 2023, CEO Bruce Broussard reviewed health insurer Humana’s transformation into a value-based care ecosystem. Under its CenterWell brand, the several millions of members in Humana Medicare Advantage plans now had access to Humana-provided primary care, home... View Details
    Keywords: Business Model; Business Units; Financing and Loans; Innovation Strategy; Growth and Development Strategy; Service Operations; Mergers and Acquisitions; Insurance; Health Care and Treatment; Partners and Partnerships; Health Industry; Insurance Industry; United States
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    • December 2008
    • Article

    Which Kind of Collaboration Is Right for You?

    By: Roberto Verganti and Gary P. Pisano
    Nowadays, virtually no companies innovate alone. Firms team up with a variety of partners, in a wide number of ways, to create new technologies, products, and services. But what is the best way to leverage the power of outsiders? To help executives answer that... View Details
    Keywords: Cost vs Benefits; Framework; Collaborative Innovation and Invention; Innovation and Management; Partners and Partnerships; Social and Collaborative Networks; Strategy
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    • Article

    The Causes and Consequences of Industry Self-Policing

    By: Jodi L. Short and Michael W. Toffel
    Innovative regulatory programs are encouraging firms to police their own regulatory compliance and voluntarily disclose, or "confess," the violations they find. Despite the "win-win" rhetoric surrounding these government voluntary programs, it is not clear why... View Details
    Keywords: Corporate Disclosure; Governance Compliance; Law Enforcement; Policy; United States
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    • 12 Jan 2011
    • Working Paper Summaries

    Modularity for Value Appropriation--How to Draw the Boundaries of Intellectual Property

    Keywords: by Carliss Y. Baldwin & Joachim Henkel
    • Research Summary

    Overview

    By: Andy Wu
    How can technology entrepreneurs build competitive advantage from the ground up? Professor Andy Wu conducts scholarly research and develops course materials that document how technology entrepreneurs can (1) organize for innovation to create new market opportunities... View Details
    Keywords: Strategy; Entrepreneurship; Venture Capital; Growth Management; Organizational Design; Organizational Structure; Technology Platform; Technological Innovation; Information Technology Industry; Retail Industry; Pharmaceutical Industry; Video Game Industry; Media and Broadcasting Industry; United States; China; Southeast Asia; South Asia
    • April 2012 (Revised February 2017)
    • Case

    Dovernet

    By: Robert Simons and Natalie Kindred
    This case illustrates the implications of using stringent performance measurement systems to create performance pressure, motivate employee achievement, and sharpen a firm's competitiveness. It opens by describing the downsides of the ruthlessly competitive culture at... View Details
    Keywords: Motivation and Incentives; Information Technology; Competitive Advantage; Decision Choices and Conditions; Organizational Culture; Performance Evaluation; Compensation and Benefits; Web Services Industry; Information Technology Industry; Vancouver
    Related
    • September 2021 (Revised March 2024)
    • Case

    Bühler: Mobilizing Industry around a Common Purpose

    By: Ranjay Gulati, Franz Wohlgezogen and Malini Sen
    Bühler Group, a Swiss multinational processing technology provider, started by selling machines for processing grains and later transitioned into selling food processing solutions. A family-owned business in the fifth generation, Bühler’s high-end milling, grinding,... View Details
    Keywords: Family Business; Customer Focus and Relationships; Machinery and Machining; Corporate Social Responsibility and Impact; Mission and Purpose; Innovation Leadership; Switzerland
    Related

      Jim Matheson

      Jim joined the HBS Faculty in 2019 and teaches the EC courses Entrepreneurial Finance and Tough Tech Ventures and is a faculty affiliate of the Business & Environment Initiative.  He is an active investor, and Board director & advisor for... View Details

      • Research Summary

      Competing on a Common Platform

      Why have over 100 firms joined the Eclipse Foundation to collectively produce an open source platform and tools for software application development? What are they trying to accomplish? This research analyzes IBMs divestment of the Eclipse Java Integrated Development... View Details
      • 15 Jul 2014
      • First Look

      First Look: July 15

      Rory McDonald, Dan Wang, and Benjamin Hallen Abstract—This paper investigates the impact of early relationships on innovation at entrepreneurial firms. Prior research has largely focused on the benefits of network ties, documenting the... View Details
      Keywords: Carmen Nobel
      • Research Summary

      Technological Change and Competitive Strategy

      Richard S. Rosenbloom continues to explore issues in the strategic management of technology and the relationship between technological change and competitive strategy. He is currently investigating the histories of radical technological innovations and their... View Details
      • 12 Aug 2018 - 14 Aug 2018
      • Conference Presentation

      Abstraction, Knowledge Flows, and the Rapid Dissemination of Emerging Technologies

      By: Willy C. Shih
      Many emerging technologies are remarkably complex and embody high levels of technological sophistication, and they often are key enablers for new products and services. Yet the speed of dispersal of the know-how required to employ these technologies and foster... View Details
      Keywords: Emerging Technologies; Technological Innovation; Knowledge Dissemination
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      • July 2010 (Revised March 2016)
      • Case

      MacroMarkets LLC

      By: Robin Greenwood and Luis M. Viceira
      MacroMarkets co-founder and CEO Samuel Masucci III is meeting with a strategic partner for his firm. Co-founded with Yale University Professor Robert Shiller, MacroMarkets' main innovation is the "MacroShare," which allows investors to take long or short, levered or... View Details
      Keywords: Macroeconomics; Financial Instruments; Financial Markets; Investment Funds; Investment Portfolio; Innovation and Invention; Risk Management; Product Positioning; Demand and Consumers; Financial Services Industry
      Related
      • 07 Dec 2011
      • News

      Cautious capitalism

      • 25 Feb 2013
      • Research & Ideas

      Lean Strategy Not Just for Start-Ups

      later stages. Network Effects Managers often think about innovation in terms of exploring new markets. But Cook said it's often wiser for firms to innovate within their... View Details
      Keywords: by Carmen Nobel; Financial Services
      • TeachingInterests

      Executive Education - Owner/President Management Program

      By: Martin A. Sinozich

      Delivered in three units that span 24 months over three calendar years, the Owner/President Management (OPM) program is a transformative learning experience that boosts leadership skills and the value of participants’ enterprises.  Sinozich teaches the Finance... View Details

      • 15 Oct 2013
      • First Look

      First Look: October 15

      Depression? By: Nanda, Ramana, and Tom Nicholas Abstract—We find a negative relationship between bank distress and the level, quality, and trajectory of firm-level innovation during the Great Depression, particularly for R&D View Details
      Keywords: Sean Silverthorne