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      • January 2024 (Revised April 2024)
      • Case

      Target Malaria: Editing Mosquitoes through Gene Drives

      By: Shikhar Ghosh and Shweta Bagai
      Target Malaria, a non-profit research consortium, is exploring the application of CRISPR-Cas9 gene editing technology to combat malaria in Sub-Saharan Africa. Its approach uses gene drives, a revolutionary tool, to suppress the population of malaria-carrying... View Details
      Keywords: Health Disorders; Technological Innovation; Nonprofit Organizations; Business Strategy; Genetics; Ethics; Governing Rules, Regulations, and Reforms; United States; United Kingdom; Burkina Faso; Africa
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      Ghosh, Shikhar, and Shweta Bagai. "Target Malaria: Editing Mosquitoes through Gene Drives." Harvard Business School Case 824-068, January 2024. (Revised April 2024.)
      • January 2024 (Revised January 2025)
      • Case

      Huawei: Resilience amid Autarky and Adversity

      By: William C. Kirby and Daniel Fu
      In September 2023, Huawei made a dramatic return to the global smartphone space with the launch of its Mate 60 Pro smartphone, equipped with an indigenously designed, 7nm chip. This came despite a myriad of export controls and restrictions imposed against the company... View Details
      Keywords: International Strategy; Semiconductors; Smartphone; Government And Politics; Government And Business; Digital Infrastructure; 5G; Political Risk; Business and Government Relations; Global Strategy; Multinational Firms and Management; Governing Rules, Regulations, and Reforms; AI and Machine Learning; Mobile and Wireless Technology; Leadership; Retirement; Corporate Strategy; Technology Industry; China; United States; Europe; Asia; Middle East
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      Kirby, William C., and Daniel Fu. "Huawei: Resilience amid Autarky and Adversity." Harvard Business School Case 324-069, January 2024. (Revised January 2025.)
      • 2024
      • Working Paper

      Private Regulation, Institutional Entrepreneurship and Climate Change: A Business History Perspective

      By: Ann-Kristin Bergquist and Geoffrey Jones
      Private regulatory systems, including voluntary efforts by firms to restrain their own behavior are the primary form of global climate change governance. However, when environmental challenges first rose up on the scientific and political agendas during the 1970s, the... View Details
      Keywords: Certification; Climate Change; Environmental Regulation; Business History; Governing Rules, Regulations, and Reforms; Policy
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      Bergquist, Ann-Kristin, and Geoffrey Jones. "Private Regulation, Institutional Entrepreneurship and Climate Change: A Business History Perspective." Harvard Business School Working Paper, No. 24-041, January 2024.
      • 2024
      • Working Paper

      Antitrust Platform Regulation and Entrepreneurship: Evidence from China

      By: Ke Rong, D. Daniel Sokol, Di Zhou and Feng Zhu
      Many jurisdictions have launched antitrust enforcement and brought in regulation of large tech platforms. The swift and strict implementation of China’s Anti-Monopoly Guidelines for the Platform Economy (Platform Guidelines) provides a quasi-natural experiment... View Details
      Keywords: Governing Rules, Regulations, and Reforms; Competition; Venture Capital; Market Entry and Exit; Supply and Industry; China
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      Rong, Ke, D. Daniel Sokol, Di Zhou, and Feng Zhu. "Antitrust Platform Regulation and Entrepreneurship: Evidence from China." Harvard Business School Working Paper, No. 24-039, January 2024.
      • January 11, 2024
      • Article

      Understanding the Tradeoffs of the Amazon Antitrust Case

      By: Chiara Farronato, Andrey Fradkin, Andrei Hagiu and Dionne Lomax
      Regulators in the United States and Europe have been taking on Big Tech, challenging what they say are the companies’ anti-competitive and predatory strategies that harm consumers and third-party users of their platforms. This article examines the FTC’s case against... View Details
      Keywords: Monopoly; Governing Rules, Regulations, and Reforms; Market Design; Lawsuits and Litigation
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      Farronato, Chiara, Andrey Fradkin, Andrei Hagiu, and Dionne Lomax. "Understanding the Tradeoffs of the Amazon Antitrust Case." Harvard Business Review Digital Articles (January 11, 2024).
      • January 2024 (Revised January 2025)
      • Case

      Colbún and Chile's Energy Transition

      By: Forest Reinhardt, Jenyfeer Martinez Buitrago and Mariana Cal
      In May 2023, Colbún, Chile’s second-largest electricity generator, plans capacity expansions using renewable energy and storage. This strategy supports Chile’s commitment to carbon neutrality (also known as net zero emissions) by 2050. The case delves into the... View Details
      Keywords: Transition; Energy Generation; Renewable Energy; Climate Change; Investment; Governing Rules, Regulations, and Reforms; Infrastructure; Organizational Change and Adaptation; Expansion; Business Strategy; Energy Industry; Utilities Industry; Latin America; South America; Chile
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      Reinhardt, Forest, Jenyfeer Martinez Buitrago, and Mariana Cal. "Colbún and Chile's Energy Transition." Harvard Business School Case 724-026, January 2024. (Revised January 2025.)
      • 2024
      • Article

      Technological Adoption and Taxation: The Case of China's Golden Tax Reform

      By: Haichao Fan, Yu Liu, Nancy Qian and Jaya Y. Wen
      This paper investigates the effect of Phase 2 of the Golden Tax Project on VAT in China. The reform introduced computer-generated invoices and electronic transaction linking. Using a difference-in-differences strategy, we show that the reform increased VAT by reducing... View Details
      Keywords: Taxation; Governing Rules, Regulations, and Reforms; Technological Innovation; Economic Growth; China
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      Fan, Haichao, Yu Liu, Nancy Qian, and Jaya Y. Wen. "Technological Adoption and Taxation: The Case of China's Golden Tax Reform." Tax Policy and the Economy 38 (2024): 101–122.
      • 2024
      • Chapter

      The Private Economy Under Party-State Capitalism

      By: Margaret M. Pearson, Meg Rithmire and Kellee S. Tsai
      This chapter addresses the evolution of China’s approach to the private sector from the early reform era until the beginning of Xi Jinping’s third term. It argues that China has evolved from a familiar form of state capitalism, in which economic growth is the primary... View Details
      Keywords: Government Administration; International Relations; Economic Growth; Economic Sectors; Economic Systems; China
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      Pearson, Margaret M., Meg Rithmire, and Kellee S. Tsai. "The Private Economy Under Party-State Capitalism." Chap. 3 in Chinese Politics: The Xi Jinping Difference. 2nd edition edited by Stanley Rosen and Daniel C. Lynch, 67–82. Routledge, 2024.
      • December 2023
      • Case

      The American Bully XL

      By: Robin Greenwood, Richard S. Ruback, Johnathan Sun and Robert Ialenti
      The American Bully XL, first introduced to the United Kingdom around 2014, had been held responsible for a disproportionate share of both dog-related attacks and deaths. The case discusses the announcement, in October 2023, that the dog breed would be added to a list... View Details
      Keywords: Governing Rules, Regulations, and Reforms; Policy; Government Administration; Laws and Statutes; Risk and Uncertainty; United Kingdom
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      Greenwood, Robin, Richard S. Ruback, Johnathan Sun, and Robert Ialenti. "The American Bully XL." Harvard Business School Case 224-051, December 2023.
      • December 2023 (Revised May 2024)
      • Case

      Building Resiliency in McDonald's Supply Chain

      By: David E. Bell, Damien McLoughlin and David Lane
      Considers McDonald’s efforts to build resilience into its global supply chain so that the company and its suppliers can better navigate the increasing pressures and pace of climate change and regulatory change, including a focus on supplying sustainable beef, while the... View Details
      Keywords: Climate Change; Supply Chain Management; Business and Stakeholder Relations; Risk and Uncertainty; Governing Rules, Regulations, and Reforms; Growth Management; Agriculture and Agribusiness Industry; Food and Beverage Industry; United States; Europe; South America
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      Bell, David E., Damien McLoughlin, and David Lane. "Building Resiliency in McDonald's Supply Chain." Harvard Business School Case 524-001, December 2023. (Revised May 2024.)
      • December 2023 (Revised August 2024)
      • Case

      Monsters in the Machine? Tackling the Challenge of Responsible AI

      By: Paul M. Healy and Debora L. Spar
      In November of 2022, the small tech company OpenAI released ChatGPT, an artificial intelligence chatbot which quickly captured the public’s imagination—becoming the world’s fastest-growing consumer application within months of its release. Though observers from across... View Details
      Keywords: Technological Innovation; AI and Machine Learning; Ethics; Governing Rules, Regulations, and Reforms; Technology Adoption; Corporate Social Responsibility and Impact; Technology Industry; United States; European Union; China
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      Healy, Paul M., and Debora L. Spar. "Monsters in the Machine? Tackling the Challenge of Responsible AI." Harvard Business School Case 324-062, December 2023. (Revised August 2024.)
      • November–December 2023
      • Article

      Tax-Loss Harvesting with Cryptocurrencies

      By: Lin William Cong, Wayne Landsman, Edward Maydew and Daniel Rabetti
      We describe the taxation landscape in the cryptocurrency markets, especially concerning U.S. taxpayers, and examine how recent increases in tax scrutiny have led to changes in crypto investors' trading behavior. We argue conceptually and then empirically document that... View Details
      Keywords: Cryptocurrency; Taxation; Governing Rules, Regulations, and Reforms; Financial Markets
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      Cong, Lin William, Wayne Landsman, Edward Maydew, and Daniel Rabetti. "Tax-Loss Harvesting with Cryptocurrencies." Art. 101607. Journal of Accounting & Economics 76, nos. 2-3 (November–December 2023).
      • November 2023 (Revised March 2024)
      • Technical Note

      Customer Data Privacy

      By: Eva Ascarza and Ta-Wei Huang
      This note provides an overview of the evolving landscape of customer data privacy in 2023. It highlights two pivotal aspects that make privacy a central concern for businesses: building and maintaining customer trust and navigating the intricate regulatory... View Details
      Keywords: Customer Relationship Management; Governance Compliance; Governing Rules, Regulations, and Reforms; Risk and Uncertainty; Reputation; Trust; Information Management; Retail Industry; Technology Industry; Financial Services Industry; Telecommunications Industry; Europe; United States
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      Ascarza, Eva, and Ta-Wei Huang. "Customer Data Privacy." Harvard Business School Technical Note 524-005, November 2023. (Revised March 2024.)
      • November 2023
      • Case

      Will Fintechs and Central Banks Play in Emtech's Sandbox?

      By: Daniel Isenberg and William R. Kerr
      In February 2023, Emtech’s founder Carmelle Cadet is facing a dilemma. Rapidly running out of cash, Cadet has a term sheet from a leading VC but has a choice of how to structure the investment. The decision will have significant implications for Cadet’s own stake, as... View Details
      Keywords: Cryptocurrency; Business Startups; Venture Capital; Cash Flow; Currency; Governing Rules, Regulations, and Reforms; Digital Platforms
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      Isenberg, Daniel, and William R. Kerr. "Will Fintechs and Central Banks Play in Emtech's Sandbox?" Harvard Business School Case 824-096, November 2023.
      • 2023
      • Working Paper

      The Political Economy of a 'Miracle Cure': The Case of Nebulized Ibuprofen and Its Diffusion in Argentina

      By: Sebastian Calónico, Rafael Di Tella and Juan Cruz Lopez Del Valle
      We document the diffusion of nebulized ibuprofen in Argentina as a treatment for COVID-19. As the pandemic spread, this clinically unsupported drug reached thousands of patients, even some seriously ill, despite warnings by the regulator and medical societies. Detailed... View Details
      Keywords: COVID-19; Health Care and Treatment; Health Pandemics; Adoption; Behavior; Governing Rules, Regulations, and Reforms; Learning
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      Calónico, Sebastian, Rafael Di Tella, and Juan Cruz Lopez Del Valle. "The Political Economy of a 'Miracle Cure': The Case of Nebulized Ibuprofen and Its Diffusion in Argentina." NBER Working Paper Series, No. 31781, October 2023.
      • October 2023 (Revised May 2024)
      • Case

      JSW Steel: Balancing Growth While Decarbonizing

      By: Vikram S Gandhi and Radhika Kak
      Sajjan Jindal, Chairman & Managing Director of JSW Steel, India's largest steel producer by market capitalization, was facing a dilemma. Steel demand in India was expected to grow exponentially over the next decade. However, given its traditional reliance on carbon,... View Details
      Keywords: Decisions; Environmental Sustainability; Investment; Governing Rules, Regulations, and Reforms; Growth and Development; Corporate Social Responsibility and Impact; Pollutants; Pollution; Production; Steel Industry; India
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      Gandhi, Vikram S., and Radhika Kak. "JSW Steel: Balancing Growth While Decarbonizing." Harvard Business School Case 824-002, October 2023. (Revised May 2024.)
      • September 2023
      • Case

      The Rise and Fall of FTX

      By: Aiyesha Dey, Jonas Heese, Joseph Pacelli and Max Hancock
      In November 2022, Sam Bankman-Fried's multi-billion-dollar crypto exchange, FTX, collapsed, wiping out investors and throwing the crypto industry into disarray. As FTX's founder and CEO, Bankman-Fried developed a reputation for his unerring business sense and... View Details
      Keywords: Cryptocurrency; Crime and Corruption; Financial Statements; Misleading and Fraudulent Advertising; Insolvency and Bankruptcy; Corporate Governance; Governing Rules, Regulations, and Reforms; Failure; Restructuring; United States; Hong Kong; Bahamas
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      Dey, Aiyesha, Jonas Heese, Joseph Pacelli, and Max Hancock. "The Rise and Fall of FTX." Harvard Business School Case 124-014, September 2023.
      • September 2023
      • Article

      (Not) Paying for Diversity: Repugnant Market Concerns Associated with Transactional Approaches to Diversity Recruitment

      By: Summer R. Jackson
      In a 20-month ethnographic study, I examine how a technology firm, ShopCo (a pseudonym), considered 13 different recruitment platforms to attract racial minority engineering candidates. I find that when choosing whether to adopt recruitment platforms focused on racial... View Details
      Keywords: Technology Adoption; Recruitment; Race; Organizational Change and Adaptation
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      Jackson, Summer R. "(Not) Paying for Diversity: Repugnant Market Concerns Associated with Transactional Approaches to Diversity Recruitment." Administrative Science Quarterly 68, no. 3 (September 2023): 824–866.
      • August 2023 (Revised May 2024)
      • Case

      Dicerna Pharmaceuticals: Decision Making in Clinical Trial Design and Operations

      By: Satish Tadikonda and Amanda McEwen
      The success or failure of Dicerna Pharmaceuticals (Dicerna) as an emerging pharmaceutical company would likely hinge on its lead drug candidate Nedosiran and the company’s ability to see it successfully through clinical development. Ralf Rosskamp, Chief Medical... View Details
      Keywords: Business Strategy; Health Testing and Trials; Product Development; Governing Rules, Regulations, and Reforms; Pharmaceutical Industry
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      Tadikonda, Satish, and Amanda McEwen. "Dicerna Pharmaceuticals: Decision Making in Clinical Trial Design and Operations." Harvard Business School Case 824-018, August 2023. (Revised May 2024.)
      • August 2023 (Revised October 2023)
      • Case

      Beyond the Barricades: Chile 2023

      By: Debora Spar, Willis Emmons, Leonard A. Schlesinger and Ruth Costas
      Chile, often considered among Latin America's greatest economic success stories, suffered a shocking wave of protests in October 2019, as its citizens demanded reforms across healthcare and education systems, and protested inequality and rising costs of living. As... View Details
      Keywords: Government Administration; Developing Countries and Economies; Economic Growth; Social Issues; Wealth and Poverty; Public Opinion; Equality and Inequality; Public Administration Industry; Chile; Latin America; South America
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      Spar, Debora, Willis Emmons, Leonard A. Schlesinger, and Ruth Costas. "Beyond the Barricades: Chile 2023." Harvard Business School Case 324-005, August 2023. (Revised October 2023.)
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