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2022
Working Paper

Machine Learning Models for Prediction of Scope 3 Carbon Emissions

By: George Serafeim and Gladys Vélez Caicedo

For most organizations, the vast amount of carbon emissions occur in their supply chain and in the post-sale processing, usage, and end of life treatment of a product, collectively labelled scope 3 emissions. In this paper, we train machine learning algorithms on 15... View Details

Keywords: Carbon Emissions; Climate Change; Environment; Carbon Accounting; Machine Learning; Artificial Intelligence; Digital; Data Science; Environmental Sustainability; Environmental Management; Environmental Accounting

March 2011
Supplement

Padraig O'Ceidigh and Aer Arann: Building a Business in the Context of a Life - What Happened

By: Janet J. Kraus and Shirley Spence

Provides an epilogue to the problem posed in the companion case: what to do in the face of potential liquidation? View Details

Keywords: Natural Disasters; Crisis Management; Air Transportation; Entrepreneurship; Management Teams; Business or Company Management; Success; Decision Making; Air Transportation Industry; Republic of Ireland

29 May 2001
Research & Ideas

Genomics: Can We Start Making Money Now?

drugs, and will they be less expensive?' My answer is, 'I don't know, and probably not.' Lechleiter was one of several panelists to discuss, "Breaking the Genetic Code: The Business of Life Science in... View Details

Keywords: by Sean Silverthorne

2020
Working Paper

A Preliminary Framework for Product Impact-Weighted Accounts

By: George Serafeim and Katie Trinh

While there has been significant progress in the measurement of an organization’s environmental and social impacts from its operations, metrics to evaluate the impact of products once they come to market lag far behind. In this paper, we provide a framework for... View Details

Keywords: Social Impact; Product Life Cycle; Environment; Sustainability; Measurement; Metrics; Impact Investing; ESG; ESG (Environmental, Social, Governance) Performance; ESG Reporting; Product; Environmental Sustainability; Measurement and Metrics; Framework; Financial Statements

December 2004 (Revised April 2014)
Case

Stan Lapidus: Profile of a Medical Entrepreneur

By: Robert F. Higgins and Sophie LaMontagne

Describes the career path and insights of Stanley Lapidus, a successful serial entrepreneur in the medical and life sciences industry. Lapidus is the founder of Cytyc Corp. (NASDAQ: CYTC) and EXACT Sciences (NASDAQ: EXAS) and is currently the CEO of his third start-up,... View Details

Keywords: Business Startups; Experience and Expertise; Entrepreneurship; Venture Capital; Managerial Roles; Health Industry

September 2013 (Revised August 2014)
Case

Claritas Genomics

By: Robert F. Higgins and Matthew Preble

Claritas Genomics was formed in January 2013 when BCH spun out its Genetics Diagnostic Lab into a fully commercial entity. Claritas offered over 100 genomic tests to detect a range of conditions, including autism and intellectual disabilities, and was developing new... View Details

19 Oct 2015
Research & Ideas

Business Research that Makes for Smarter Public Policy

to fill little gaps in the literature, and I continue to think that was excellent advice.” Just as researchers in the life sciences often target their work to tackle the most dangerous diseases, so argues... View Details

Keywords: by Michael Blanding

11 Nov 2015
Working Paper Summaries

Public R&D Investments and Private-sector Patenting: Evidence from NIH Funding Rules

Keywords: by Danielle Li; Health; Biotechnology; Pharmaceutical; Medical Devices & Supplies

November 2016 (Revised April 2017)
Case

Basecamp: Pricing

By: Frank Cespedes and Robb Fitzsimmons

A data analyst at Basecamp is evaluating the results of pricing research and its potential implications for the venture’s latest version of its project management software product. View Details

Keywords: Pricing; Entrepreneurial Management; Data Analysis; Marketing; Customer Acquisition; Customer Retention; Value Proposition; Sales Management; Product Management; Market Research; Life Time Value; Testing; Entrepreneurship; Analytics and Data Science; Customers; Value; Sales; Product Marketing; United States

May 2014 (Revised November 2014)
Case

Houston We Have A Problem: NASA and Open Innovation (A)

By: Michael Tushman, Hila Lifshitz-Assaf and Kerry Herman

Jeff Davis, director of Space Life Sciences Directorate (SLSD) at NASA, has been working for several years to raise awareness amongst scientists and researchers in his organizations of the benefits of open innovation as a successful and efficient way to collaborate on... View Details

October 2023 (Revised June 2024)
Case

Revvity: A Symbol of Change

By: Satish Tadikonda and William Marks

After selling the PerkinElmer name and several ancillary business units, Prahlad Singh (CEO) and his team at the newly christened Revvity faced a challenge on how best to capitalize on the opportunities ahead for the business and emerge as winners within the Life... View Details

Keywords: Business Model; Organizational Change and Adaptation; Corporate Strategy

October 2023 (Revised April 2024)
Case

Veeva Systems: The Next Frontier

By: Satish Tadikonda and William Marks

Born out of a desire to bring technological advances in enterprise software into the healthcare vertical, Peter Gassner and Matt Wallach founded Veeva to bring life sciences companies into the digital age for data management in both the commercial and R&D sectors. Over... View Details

Keywords: Business Model; Governance Compliance; Applications and Software; Growth Management; Expansion; Technology Industry

June 2004 (Revised November 2004)
Case

Acorda Therapeutics: Rebuilding the Spinal Cord

Acorda is an early-stage life science start-up with a promising product that is close to reaching the market (Phase III clinical trials). The company is grappling with how to expand its portfolio of molecules to make the business more sustainable. It faces classic... View Details

Keywords: Decision Making; Science-Based Business; Health Testing and Trials; Business Startups; Product Development; Biotechnology Industry

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2020
Book

Healthy Buildings: How Indoor Spaces Drive Performance and Productivity

By: Joseph Allen and John D. Macomber

By the time you reach 80, you will have spent 72 years of your life indoors. Like it or not, humans have become an indoor species. This means that the people who design, build, and maintain our buildings can have a major impact on our health.
Ever feel tired... View Details

Keywords: Architecture; Real Estate Development; Air Pollution; Air Quality; Public Health; Productivity Gains; Buildings and Facilities; Health; Pollutants; Performance Productivity; Construction Industry

Find at Harvard

12 Sep 2023
Book

Successful, But Still Feel Empty? A Happiness Scholar and Oprah Have Advice for You

goals, is the backbone of Brooks’ new book with Oprah Winfrey, Build the Life You Want: The Art and Science of Getting Happier. They weave together the best happiness how-tos from social psychology,... View Details

Keywords: by Avery Forman

September 2009 (Revised September 2010)
Case

Avid Radiopharmaceuticals and Lighthouse Capital Partners

By: Matthew Rhodes-Kropf and Ann Leamon

In fall 2008, a venture lender must decide whether to make a loan to Avid, a small but promising venture-backed life sciences firm. In reviewing her proposal, Cristy Barnes considers the company's characteristics and how they differ from a typical investment. At the... View Details

Keywords: Business Startups; Decision Choices and Conditions; Financial Crisis; Venture Capital; Private Equity; Financing and Loans; Investment; Financial Services Industry; Health Industry

02 Jan 2024
What Do You Think?

Do Boomerang CEOs Get a Bad Rap?

Kolev, “Boomerang CEOs: What Happens When the CEO Comes Back?,” MIT Sloan Management Review, September 17, 2020, Kenan Institute of Private Enterprise Research Paper No. 19-27, also available at through the Social Science Research Network... View Details

Keywords: by James Heskett

March 2024
Supplement

Miracle Therapeutics (B)

By: Satish Tadikonda, William Marks and Wendi Yajnik

Supplements the (A) case. Following on the negotiations detailed in the Miracle Therapeutics (A) case, Beth Sharp and Jennifer Brilliant from Miracle Therapeutics face new challenges with their company's funding and intellectual property (IP) after several missteps.... View Details

Keywords: Business Startups; Financing and Loans; Intellectual Property; Problems and Challenges; Business or Company Management

January 2013 (Revised September 2013)
Case

Royal DSM: Fighting Hidden Hunger

By: Rebecca Henderson, Noah Fisher and Mary Shelman

In 2007 Royal DSM, a leading life science and materials company, entered a partnership with the World Food Programme (WFP) to combat hidden hunger around the world by providing micronutrient solutions. The case investigates the unexpectedly large impact the partnership... View Details

Keywords: Conflict of Interests; Human Needs; Partners and Partnerships; Global Range; Nutrition; Science-Based Business; Non-Governmental Organizations; Service Industry; Health Industry

2011
Book

Getting to Giving: Fundraising the Entrepreneurial Way

By: Howard H. Stevenson and Shirley M. Spence

Getting to Giving is based on Stevenson's many years as a donor, fundraiser and entrepreneur. The book offers practical techniques and real life stories, and brings passion and humor to the art and science of asking for money. Topics included in the book... View Details

Keywords: Fund Raising; Fundraising; Non-profit Management; Strategy; Nonprofit Organizations; Philanthropy and Charitable Giving

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