Publications

Educators

Willy Shih is the Robert and Jane Cizik Professor of Management Practice in Business Administration. He is part of the Technology and Operations Management Unit, and he teaches in the MBA and Executive Education Programs. His expertise is in manufacturing, product... View Details

Keywords: aerospace; automotive; biotechnology; communications; computer; digital imaging; electrical equipment; electronics; entertainment; high technology; industrial goods; information technology industry; manufacturing; retailing; semiconductor

29 May 2013
Research & Ideas

Faculty Symposium Showcases Breadth of Research

going on at the School. This year the presentation topics included the human tendency toward dishonesty, the use of crowdsourcing to solve major scientific problems, and the impact of private equity investments. Understanding Dishonesty... View Details

Keywords: by Carmen Nobel; Financial Services

October 2016
Article

Looking Across and Looking Beyond the Knowledge Frontier: Intellectual Distance and Resource Allocation in Science

By: Kevin J. Boudreau, Eva Guinan, Karim R. Lakhani and Christoph Riedl

Selecting among alternative innovative projects is a core management task in all innovating organizations. In this paper, we focus on the evaluation of frontier scientific research projects. We argue that the "intellectual distance" between the knowledge embodied in... View Details

Keywords: Knowledge; Innovation; Novelty; Evaluation; Resource Allocation; Decision Choices and Conditions; Innovation and Management; Science-Based Business; Experience and Expertise

SSRN

2015
Book

How Culture Shapes the Climate Change Debate

By: Andrew J. Hoffman

Though the scientific community largely agrees that climate change is underway, debates about this issue remain fiercely polarized. These conversations have become a rhetorical contest, one where opposing sides try to achieve victory through playing on fear, distrust,... View Details

Keywords: Climate Change; Culture; Values and Beliefs; Knowledge Dissemination

May 2008 (Revised May 2008)
Case

Symyx Technologies, Inc.

By: H. Kent Bowen, Courtney Purrington and Thomas D. Perry

Symyx is a science-based company spun out of Berkeley. Its unique materials technology has been exploited for 10 years, but the company needs a new business model. The company concept required the invention of hardware and software to do high throughput materials... View Details

Keywords: Business Model; Transition; Engineering; Technological Innovation; Resource Allocation; Product Development; Partners and Partnerships; Science-Based Business; Information Infrastructure; Applications and Software

December 2005 (Revised August 2006)
Case

Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug

By: Felix Oberholzer-Gee and Dennis A. Yao

Amgen Inc.'s Epogen was the first biotech blockbuster drug. Epogen helped prevent anemia, a condition that leads to severe fatigue, increased risk of cardiovascular disease, and even death. At the time, the market for Epogen, which included dialysis patients and... View Details

Keywords: Health Care and Treatment; Strategic Planning; Competition; Patents; Innovation and Invention; Pharmaceutical Industry; Biotechnology Industry; United States

Educators

20 Nov 2006
Research & Ideas

Open Source Science: A New Model for Innovation

scientific problem solving? Yes, and it comes from an unexpected and unrelated corner of the universe: open source software development. That's the view of Karim R. Lakhani, an assistant professor at Harvard Business School with an... View Details

Keywords: by Martha Lagace

27 Feb 2024
Blog Post

Fighting Cancer with a Novel Cell Therapy: Ananya Zutshi (MS/MBA '21)

Ananya Zutshi (MS/MBA 2021) wanted a career in pharmacology biotech, but wasn’t sure if she wanted to be on the management side or scientific side. She studied biomedical engineering as an undergraduate at... View Details

Stefan H. Thomke

Stefan Thomke (sthomke@hbs.edu), an authority on the management of innovation, is the William Barclay Harding Professor of Business Administration at Harvard Business School. He has worked with firms on product, process, and... View Details

08 Oct 2020
HBS Seminar

Ginger Jin, University of Maryland

12 Apr 2022
Blog Post

The Many Languages of Medicine to Impact Care Delivery

studying mechanisms of disease. Now, I was charged with understanding the manifestations of disease and tailoring management decisions for each patient holding their sociocultural values, socioeconomic status, and religious affiliation in... View Details

Article

Act Like a Scientist: Great Leaders Challenge Assumptions, Run Experiments, and Follow the Evidence

By: Stefan Thomke and Gary W. Loveman

Though they’ve been warned for decades about the dangers of overrelying on gut instinct and personal experience, managers keep failing to critically examine—much less challenge—the ideas their decisions are based on. To correct this problem they need to think and act... View Details

Keywords: Innovation and Management; Decision Making; Science; Leadership Style

Read Now

September 2011 (Revised October 2012)
Case

Ganging Up on Cancer: Integrative Research Centers at the Dana-Farber Cancer Institute (A)

By: Heidi K. Gardner, Edo Bedzra and Shereef M. Elnahal

Dr. Barrett Rollins, Chief Scientific Officer of the Dana Farber Cancer Institute, attempts to engender cross-scientist collaboration by applying project management principles to medical research. The resulting innovation, Integrative Research Centers, are novel in... View Details

Keywords: Problems and Challenges; Organizational Change and Adaptation; Change Management; Motivation and Incentives; Employees; Performance Evaluation; Leadership Style; Leadership; Collaborative Innovation and Invention; Innovation and Management

Educators

Professor Toffel is the Senator John Heinz Professor of Environmental Management. His research examines how companies are addressing climate change (especially decarbonization) and other environmental and working condition issues in their operations and supply... View Details

2020
Working Paper

Building the Professional Firm: McKinsey & Co.: 1939-1968

By: Amar Bhidé

This case history analyzes how the founders of McKinsey & Co. built one of the world's leading management consulting firms by developing a “system” of professional norms, approach to serving clients, personnel policies, organization, governance, and ownership. The... View Details

Keywords: McKinsey ＆ Co.; Company History; Professional Norms; Vision; Organizations; Business History; Business Model; Strategy; Consulting Industry

SSRN

Read Now

20 Jun 2019
Blog Post

What is the MS/MBA Biotechnology: Life Sciences Program? A Q&A with Bill Anderson, Senior Lecturer on Stem Cell and Regenerative Biology

Boston? Absolutely – there is no better place. Boston is the epicenter for biotech and pharma. Large companies have a major footprint here, and there is extensive experience in the faculty of bench-to-bedside approaches. The breadth of research in the View Details

2010
Working Paper

Boundary Spanning in a For-profit Research Lab: An Exploration of the Interface Between Commerce and Academe

By: Christopher C. Liu and Toby E. Stuart

In innovative industries, private-sector companies increasingly are participants in open communities of science and technology. To participate in the system of exchange in such communities, firms often publicly disclose what would otherwise remain private discoveries.... View Details

Keywords: For-Profit Firms; Higher Education; Information Publishing; Innovation and Invention; Science-Based Business; Social and Collaborative Networks; Boundaries; Biotechnology Industry; Pharmaceutical Industry

Read Now

The Chair in Entrepreneurial Leadership and Associate Professor of Strategy, DeGroote School of Business

Goran Calic is the Chair in Entrepreneurial Leadership and Associate Professor of Strategy at the DeGroote School of Business, McMaster University, where... View Details

December 2022
Article

Cost Standard Set Program: Moving Forward to Standardization of Cost Assessment Based on Clinical Condition

By: Anna Paula Beck da Silva Etges, Richard D. Urman, Anne Geubelle, Robert Kaplan and Carisi Anne Polanczyk

This communication announces the International Cost Standard Set Program. Its goal is to establish global standardized frameworks for measuring the costs of treating specific clinical conditions. A scientific committee, including 16 international healthcare cost... View Details

Keywords: Time-Driven Activity-Based Costing; Value-based Health Care; Cost; Health Care and Treatment; Activity Based Costing and Management; Health Industry