Publications

2007
Chapter

Collaborative R&D in Management: The Practical Experience of Fenix and TruePoint in Bridging the Divide Between Scientific and Managerial Goals

By: Michael Beer and Niclas Adler

The gap between theory and practice has been of concern to both practitioners and academics, yet other than pleas to close the gap with more accessible writing by academics and more interest in research by practitioners few systematic efforts have been made to close... View Details

Keywords: Transformation; Knowledge Management; Management; Goals and Objectives; Performance Effectiveness; Performance Improvement; Practice; Research and Development; Social and Collaborative Networks; Theory; Value; United States

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November 2006 (Revised March 2008)
Case

The Harvard Stem Cell Institute

By: William A. Sahlman

Describes a set of issues confronting the leaders of the Harvard Stem Cell Institute, an innovative cross-university effort to accelerate scientific discovery and translation in the domain of stem cells. Covers a wide range of topics, including understanding how... View Details

Keywords: Talent and Talent Management; Higher Education; Entrepreneurship; Collaborative Innovation and Invention; Intellectual Property; Research and Development; Genetics; Biotechnology Industry; Health Industry; Massachusetts

May 2006 (Revised June 2006)
Case

Codon Devices

By: Joseph B. Lassiter III and David Kiron

In December 2005, 40-year-old John Danner was about to make his first presentation to the board of directors of Codon Devices, a one-year-old biotechnology start-up based in Cambridge, Massachusetts. After a month as the company's CEO, Danner was prepared to lay out... View Details

Keywords: Strategic Planning; Venture Capital; Intellectual Property; Governing and Advisory Boards; Genetics; Competitive Advantage; Science-Based Business; Business Startups; Growth and Development Strategy; Biotechnology Industry; Cambridge

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May 2006
Case

A123Systems

By: H. Kent Bowen, Kenneth P Morse and Douglass Cannon

A 123Systems was a young company that was founded on basic materials science research at the Massachusetts Institute of Technology. A co-founder of the company, Yet-Ming Chiang, was a full professor at MIT and served as scientific adviser. Intellectual property based... View Details

Keywords: Intellectual Property; Business Startups; Research and Development; Commercialization; Technological Innovation; Science-Based Business; Product Development; Battery Industry; Electronics Industry; Massachusetts

March 2006
Case

The Whitesides Lab

By: H. Kent Bowen and Francesca Gino

A significant part of the long-term economic growth in developed economies depends on the translation of scientific research into new products and processes. Focuses on the front end of this value creation stream. The laboratory of George Whitesides has a 30-year... View Details

Keywords: Research; Performance Productivity; Economic Growth; Infrastructure; Creativity; Groups and Teams; Value Creation; Factories, Labs, and Plants; Leadership; Resource Allocation

January 2006 (Revised February 2015)
Case

Innovation at Timberland: Thinking Outside the Shoe Box

By: Rosabeth M. Kanter and Ryan Raffaelli

Innovation was linked to Timberland's heritage. In 2005, CEO Jeff Swartz and COO Ken Pucker hoped the Invention Factory, an advanced concept lab, would develop new breakthrough products and reinvigorate the company's culture of innovation. Since the 1960s, Timberland... View Details

Keywords: Innovation and Management; Growth and Development Strategy; Product Development; Organizational Culture; Change Management

January 2006
Case

Jack Strang at SequenceLabs

By: Mukti Khaire, John J. Gabarro and Lynda M. Applegate

How can entrepreneur manage his firm if things go wrong despite having a great idea, a solid team, and financial backing? Jack Strang founded a biotech firm with his friend Peter Evans, to develop molecular pathway-based "cures" for metabolic disorders. The idea was... View Details

Keywords: Corporate Entrepreneurship; Business or Company Management; Venture Capital; Factories, Labs, and Plants; Business Growth and Maturation; Failure; Biotechnology Industry

December 2005 (Revised August 2006)
Case

Amgen Inc.'s Epogen--Commercializing the First Biotech Blockbuster Drug

By: Felix Oberholzer-Gee and Dennis A. Yao

Amgen Inc.'s Epogen was the first biotech blockbuster drug. Epogen helped prevent anemia, a condition that leads to severe fatigue, increased risk of cardiovascular disease, and even death. At the time, the market for Epogen, which included dialysis patients and... View Details

Keywords: Health Care and Treatment; Strategic Planning; Competition; Patents; Innovation and Invention; Pharmaceutical Industry; Biotechnology Industry; United States

July 2005
Case

Harvard Business School and the Making of a New Profession

By: Rakesh Khurana, Tarun Khanna and Daniel Penrice

Since its founding in 1908, Harvard Business School's mission has been to perform a much-needed service for American society by turning business management into a profession. One of the most important factors in the founding of HBS and the nation's other new business... View Details

Keywords: Business Education; Mission and Purpose; Alignment; Social Issues; Practice

January 2004 (Revised February 2005)
Background Note

A Note on Methodological Fit in Management Field Research

By: Amy C. Edmondson and Stacy McManus

To use in doctoral-level management courses on the design of field research methods. Advocates the importance of fit, or internal consistency, among the different elements of a field research project. Although the scientific method provides an essential framework for... View Details

Keywords: Management; Research

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October 2001 (Revised March 2002)
Case

Perlegen Sciences

By: Linda A. Hill and Nicole Tempest

As a biotech start-up company involved in studying human genomes, Perlegen needed to develop an organization that fostered innovation and teamwork among a group of highly trained professionals from both the science and technology fields. Perlegen's CEO, Brad Margus,... View Details

Keywords: Innovation Leadership; Groups and Teams; Management Teams; Problems and Challenges; Business Startups; Genetics; Talent and Talent Management; Innovation Strategy; Biotechnology Industry

November 1994 (Revised December 1995)
Case

Scripps Research Institute, The: November 1993 (Abridged)

By: Josh Lerner

In November 1993, Dr. Richard Lerner, president of the Scripps Research Institute, faces the challenge of maintaining his organization's financial and scientific vitality. A proposed cooperative venture with Sandoz has attracted considerable criticism. Meanwhile, a new... View Details

Keywords: Joint Ventures; Financing and Loans; Policy; Management; Organizational Change and Adaptation; Problems and Challenges; Research; Nonprofit Organizations

December 1993 (Revised November 2009)
Case

Manville Corporation Fiber Glass Group (A)

By: Lynn S. Paine and Sarah Gant

Manville Corp.'s senior managers must decide how to respond to a new scientific study suggesting that fiberglass, the source of 75% of the company's profits, may be another asbestos and must act under conditions of great uncertainty. In particular, when should a... View Details

Keywords: Communication Strategy; Decision Choices and Conditions; Ethics; Health Disorders; Risk Management; Marketing Communications; Product; Corporate Social Responsibility and Impact; Safety; Consumer Products Industry; Industrial Products Industry

January 1989 (Revised March 1995)
Case

Du Pont Freon Products Division (A)

By: Richard H.K. Vietor and Forest L. Reinhardt

In 1988, the Du Pont Co. is abruptly confronted with solid scientific evidence that chlorofluorocarbons are destroying the earth's ozone shield. Du Pont, with its Freon brand product line serving markets for foam insulation, electronics solvents, and especially... View Details

Keywords: Business Divisions; Policy; Management; Brands and Branding; Production; Service Operations; Natural Environment; Competition; Corporate Strategy; Environmental Sustainability

May 1984 (Revised July 1984)
Teaching Note

Mass Production and the Beginnings of Scientific Management, Teaching Note

By: Richard S. Tedlow

Keywords: Management; Production