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  • All HBS Web  (3,434)
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  • 2001
  • Chapter

Publicly Funded Science and the Productivity of the Pharmaceutical Industry

By: Rebecca Henderson and Ian Cockburn
U.S. taxpayers funded $14.8 billion of health related research last year, four times the amount that was spent in 1970 in real terms. In this paper we evaluate the impact of these huge expenditures on the technological performance of the pharmaceutical industry. While... View Details
Keywords: Public Sector; Science-Based Business; Research and Development; Sovereign Finance; Pharmaceutical Industry
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Henderson, Rebecca, and Ian Cockburn. "Publicly Funded Science and the Productivity of the Pharmaceutical Industry." In Innovation Policy and the Economy, Volume 1, edited by Adam B. Jaffe, Josh Lerner, and Scott Stern, 1–34. MIT Press, 2001.
  • February 2008 (Revised August 2008)
  • Case

EXACT Sciences Corp.: Commercializing a Diagnostic Test

By: Regina E. Herzlinger
This case addresses the challenges of commercializing molecular diagnostics. Along the way, it explains the technology, payment system, and the measures used to assess the value of a diagnostic test. View Details
Keywords: Health Testing and Trials; Genetics; Science-Based Business; Commercialization; Biotechnology Industry
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Herzlinger, Regina E. "EXACT Sciences Corp.: Commercializing a Diagnostic Test." Harvard Business School Case 308-090, February 2008. (Revised August 2008.)
  • September 2019
  • Case

Funding Sources for Science & Technology Start-ups in India

By: Tarun Khanna, Arjun Swarup and Rachna Tahilyani
India's start-up ecosystem is amongst the largest globally, with a variety of funding options from angel investors, venture capital and corporate venture capital to debt. Classic consumer focused start-ups which look to leverage technology have been able to raise... View Details
Keywords: Venture Capital; Business Startups; Science; Information Technology; Financial Services Industry; Banking Industry; Technology Industry; India; South Asia
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Khanna, Tarun, Arjun Swarup, and Rachna Tahilyani. "Funding Sources for Science & Technology Start-ups in India." Harvard Business School Case 720-401, September 2019.
  • March 2022
  • Case

Shanghai Pudong Science and Technology Investment Co., Ltd.: December 2014

By: Josh Lerner, Luyang Zhang, Xinlai Tong and Yue Kong
In early December 2014, the senior team of Pudong Science and Technology Investment (hereafter, Pudong S&T) gathered in the offices of their chairman, Dr. Xudong Zhu. Before completing its cross-border acquisition of Montage Technology, Pudong S&T—wholly owned by the... View Details
Keywords: Mergers and Acquisitions; Ownership Stake; Risk Management; Ownership Type; China
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Lerner, Josh, Luyang Zhang, Xinlai Tong, and Yue Kong. "Shanghai Pudong Science and Technology Investment Co., Ltd.: December 2014 ." Harvard Business School Case 822-111, March 2022.
  • April 2024 (Revised November 2024)
  • Case

Moderna: Pioneering a People Platform to Accelerate Science Innovation

By: Tatiana Sandino, Emil Dy and Samuel Grad
Moderna was founded in 2010 to explore how messenger ribonucleic acid (mRNA) could be used to create breakthrough medicines by encoding instructions for the body to create antibodies. When Stéphane Bancel (HBS 2000) took over in 2011, he bet on the potential of this... View Details
Keywords: Disruptive Innovation; Talent and Talent Management; Selection and Staffing; AI and Machine Learning; Digital Strategy; Innovation and Management; Leadership Development; Management Practices and Processes; Management Systems; Organizational Culture; Performance Evaluation; Alignment; Employee Relationship Management; Science-Based Business; Expansion; Pharmaceutical Industry; Biotechnology Industry; United States
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Sandino, Tatiana, Emil Dy, and Samuel Grad. "Moderna: Pioneering a People Platform to Accelerate Science Innovation." Harvard Business School Case 124-091, April 2024. (Revised November 2024.)
  • May 9, 2024
  • Article

Business Education Is Broken: Here Are Strategies to Fix It

By: Andrew J. Hoffman
Business schools have lost their way. Students are schooled in a system that, having raised the standard of living for millions of people over centuries, is now facing systemic failures in both the environmental and social domains—failures that market forces cause and,... View Details
Keywords: Education Reform; Business And Society; Climate Change; Equality and Inequality; Environmental Sustainability; Business Education
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Hoffman, Andrew J. "Business Education Is Broken: Here Are Strategies to Fix It." Inspiring Minds (May 9, 2024).
  • August 2017 (Revised August 2018)
  • Case

Busbud: Building a Data Company

By: Srikant M. Datar, Alistair Croll and Caitlin N. Bowler
The case features the work of LP Maurice (HBS '08) as he decides to take on the fragmented bus travel industry and launch an online business that aggregates and shares bus schedules for routes around the world. His first challenge: finding that the data he needs is... View Details
Keywords: Data Science; Analytics and Data Science; Business Startups; Knowledge Acquisition; Customers; Measurement and Metrics; Transportation Industry
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Datar, Srikant M., Alistair Croll, and Caitlin N. Bowler. "Busbud: Building a Data Company." Harvard Business School Case 118-011, August 2017. (Revised August 2018.)
  • March 2017 (Revised February 2025)
  • Case

Edwin Land: The Art and Science of Innovation

By: Tom Nicholas, Christopher T. Stanton and Matthew G. Preble
Throughout the second half of the 20th century, Polaroid first invented—and then continuously reinvented—the field of instant photography. Under the leadership of its mercurial founder Edwin Land, the company regularly released new instant cameras and films, often... View Details
Keywords: Instant Photography; Company History; Change Management; Disruption; Forecasting and Prediction; Entrepreneurship; Business History; Innovation Strategy; Disruptive Innovation; Innovation and Management; Intellectual Property; Patents; Product Marketing; Brands and Branding; Product Launch; Product Development; Chemical Industry; Consumer Products Industry; United States
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Nicholas, Tom, Christopher T. Stanton, and Matthew G. Preble. "Edwin Land: The Art and Science of Innovation." Harvard Business School Case 817-107, March 2017. (Revised February 2025.)
  • 01 Mar 2004
  • Lessons from the Classroom

Mission to Mars: It Really Is Rocket Science

substantially, NASA would have to place much greater emphasis on technology re-use, developing designs that were expected to fulfill multiple missions. In this respect, borrowing some ideas from business could help. For example, NASA... View Details
Keywords: by Sean Silverthorne
  • 2001
  • Chapter

Transforming Life, Transforming Business: The Life Science Revolution

By: Juan Enriquez and Ray A. Goldberg
Keywords: Science-Based Business; Organizational Change and Adaptation; Human Needs; Welfare; Transformation
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Enriquez, Juan, and Ray A. Goldberg. "Transforming Life, Transforming Business: The Life Science Revolution." In The Digital Enterprise: How To Reshape Your Business For A Connected World, edited by Nicholas G. Carr. Boston: Harvard Business School Press, 2001.
  • 2022
  • Book

Purpose + Profit: How Business Can Lift Up the World

By: George Serafeim
The roadmap and best practices to reap the enormous value that can emerge when your business prioritizes social and environmental goals—such as climate change, diversity and inclusion, and sustainability—right alongside the pursuit of profit.

We not only... View Details
Keywords: ESG (Environmental, Social, Governance) Performance; Profitability; Business And Society; Organizations; Mission and Purpose; Goals and Objectives; Social Issues; Environmental Sustainability; Value Creation; Organizational Change and Adaptation
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Serafeim, George. Purpose + Profit: How Business Can Lift Up the World. New York: HarperCollins Leadership, 2022.
  • Teaching Interest

Harvard Business Analytics Program

By: Michael L. Tushman

The Harvard Business Analytics Program is offered through a collaboration between Harvard Business School (HBS), the John A. Paulson School of Engineering and Applied Sciences (SEAS), and the Faculty of Arts and Sciences (FAS).

Designed for... View Details

  • September 9, 2024
  • Article

Ten Questions for a Winning Climate-transition Business Strategy

By: George Serafeim
The move to a low-carbon economy will create opportunities for innovation and growth. To make the most of them, leaders must understand the challenges they could face along the way. View Details
Keywords: Technology; Organizational Transformations; Business Model Innovation; Innovation and Invention; Climate Change; Transformation; Leadership; Business Strategy; Environmental Sustainability; Change Management; Entrepreneurship
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Serafeim, George. "Ten Questions for a Winning Climate-transition Business Strategy." Strategy + Business (website) (September 9, 2024).
  • 2025
  • Book

Talk: The Science of Conversation and the Art of Being Ourselves

By: Alison Wood Brooks
We all struggle with difficult conversations, but we're often not very good at easy ones either. Though we do it all the time, conversation is one of the most complex, demanding, and delicate of all human tasks, rife with possibilities for misinterpretation and... View Details
Keywords: Interpersonal Communication
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Brooks, Alison Wood. Talk: The Science of Conversation and the Art of Being Ourselves. Crown, 2025.
  • 10 Aug 2021
  • Cold Call Podcast

The Science of Sales Conversations with Gong’s Amit Bendov

Keywords: Re: Alison Wood Brooks
  • 2010
  • Working Paper

From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science

This paper examines gender differences in the participation of university life science faculty in commercial science. Based on theory and field interviews, we develop hypotheses regarding how scientists' productivity, co-authorship networks, and institutional... View Details
Keywords: Business Startups; For-Profit Firms; Gender Characteristics; Higher Education; Entrepreneurship; Governing and Advisory Boards; Science-Based Business; Nonprofit Organizations; Biotechnology Industry
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Ding, Waverly W., Fiona Murray, and Toby E. Stuart. "From Bench to Board: Gender Differences in University Scientists' Participation in Commercial Science." Harvard Business School Working Paper, No. 11-014, August 2010.
  • Teaching Interest

Applied Business Analytics

Course Overview:

Business Analytics has become a core function in many firms today and is driving innovation in the form of new business and operating models. Data-driven decision-making requires understanding of statistics, computer... View Details

  • Fall 2020
  • Article

Climate in the Boardroom: Struggling to Reconcile Business as Usual and the End of the World as We Know It

By: Rebecca Henderson
How does one witness to businesspeople about climate change? Climate change is a problem for the collective and the long term, whereas business often requires a ruthless focus on the individual and the quarter. Climate change is an ethical catastrophe whose solution... View Details
Keywords: Sustainable Business; Climate Change; Corporate Social Responsibility and Impact; Environmental Sustainability
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Henderson, Rebecca. "Climate in the Boardroom: Struggling to Reconcile Business as Usual & the End of the World as We Know It." Special Issue on Witnessing Climate Change. Daedalus 149, no. 4 (Fall 2020): 118–124.
  • 07 Nov 2017
  • Working Paper Summaries

Business and Sustainability: New Business History Perspectives

Keywords: by Ann-Kristin Bergquist
  • October 2023 (Revised November 2023)
  • Case

Rheaply: Circularity For Every Business

By: Rembrand Koning and Alicia Dadlani
In March 2023, Garry Cooper, cofounder and CEO of Chicago-based Rheaply, needed to demonstrate that Rheaply’s expanded vision could translate into building cash flows and metrics needed to raise a Series B and turn the business into a model for financial and... View Details
Keywords: Business Startups; Social Entrepreneurship; Technological Innovation; Environmental Sustainability; Entrepreneurial Finance; Technology Industry; Green Technology Industry; United States; Illinois; Chicago
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Koning, Rembrand, and Alicia Dadlani. "Rheaply: Circularity For Every Business." Harvard Business School Case 724-351, October 2023. (Revised November 2023.)
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