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      • Faculty Publications  (276)

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      • January 2021 (Revised June 2021)
      • Case

      Hester Pharmaceuticals (A): A Pricing Dilemma

      By: Dante Roscini and John Masko
      In August 2019, the leadership of Hester Pharmaceuticals (Hester) had a problem. Italy promised to be a key market for their new breakthrough oncology drug Akrozumab, but for almost two years, its single-payer healthcare system had been unable to agree with Hester on a... View Details
      Keywords: Macroeconomics; Trade; Price; Global Range; Global Strategy; Globalized Markets and Industries; Health Care and Treatment; Patents; Monopoly; Negotiation; Business and Government Relations; Risk and Uncertainty; Human Needs; Business Strategy; Commercialization; Pharmaceutical Industry; Italy
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      Roscini, Dante, and John Masko. "Hester Pharmaceuticals (A): A Pricing Dilemma." Harvard Business School Case 721-001, January 2021. (Revised June 2021.)
      • January 2021
      • Article

      Commuting and Innovation: Are Closer Inventors More Productive?

      By: Hongyu Xiao, Andy Wu and Jaeho Kim
      We estimate the causal effect of workplace–home commuting distance on inventor productivity. We construct a novel panel of U.S. inventors with precisely measured workplace–home distances and inventor-level productivity. Our identification strategy exploits firm office... View Details
      Keywords: Commuting; Proximity; Inventors; Innovation; Relocation; Telecommuting; Geographic Location; Technological Innovation; Innovation and Management; Innovation Strategy; United States
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      Xiao, Hongyu, Andy Wu, and Jaeho Kim. "Commuting and Innovation: Are Closer Inventors More Productive?" Art. 103300. Journal of Urban Economics 121 (January 2021).
      • December 2020
      • Article

      Different Founders, Different Firms: A Comparative Analysis of Academic and Non-academic Startups

      By: Maria P. Roche, Annamaria Conti and Frank T. Rothaermel
      What role do differences in founders' occupational backgrounds play in new venture performance? Analyzing a novel dataset of 2,998 founders creating 1,723 innovative startups in biomedicine, we find that the likelihood and hazard of achieving a liquidity event are... View Details
      Keywords: Founders; Innovation; Occupational Imprinting; Academic Startups; Non-academic Startups; Founder Heterogeneity; Business Startups; Innovation and Invention; Performance; Demographics; Analysis
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      Roche, Maria P., Annamaria Conti, and Frank T. Rothaermel. "Different Founders, Different Firms: A Comparative Analysis of Academic and Non-academic Startups." Special Issue on Innovative Start-Ups and Policy Initiatives. Research Policy 49, no. 10 (December 2020).
      • 2020
      • Working Paper

      The ESG-Innovation Disconnect: Evidence from Green Patenting

      By: Lauren Cohen, Umit G. Gurun and Quoc H. Nguyen
      No firm or sector of the global economy is untouched by innovation. In equilibrium, innovators will flock to (and innovation will occur where) the returns to innovative capital are the highest. In this paper, we document a strong empirical pattern in green patent... View Details
      Keywords: ESG (Environmental, Social, Governance) Performance; Investment; Decision Making; Policy; Energy; Green Technology; Technological Innovation; Patents
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      Cohen, Lauren, Umit G. Gurun, and Quoc H. Nguyen. "The ESG-Innovation Disconnect: Evidence from Green Patenting." NBER Working Paper Series, No. 27990, October 2020. (Winner of the Fordham University Gabelli School of Business – PVH Corp. Global Thought Leadership Grant on Corporate Social Responsibility, 2020.)
      • Article

      Foreign Competition and Domestic Innovation: Evidence from U.S. Patents

      By: David Autor, David Dorn, Gordon H. Hanson, Gary P. Pisano and Pian Shu
      Manufacturing accounts for more than three-quarters of U.S. corporate patents. The competitive shock to this sector emanating from China's economic ascent could in theory either augment or stifle U.S. innovation. Using three decades of U.S. patents matched to corporate... View Details
      Keywords: Patents; Production; Trade; Competition; Innovation and Invention; United States
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      Autor, David, David Dorn, Gordon H. Hanson, Gary P. Pisano, and Pian Shu. "Foreign Competition and Domestic Innovation: Evidence from U.S. Patents." American Economic Review: Insights 2, no. 3 (September 2020): 357–374.
      • Summer 2020
      • Article

      Tech Clusters

      By: William R. Kerr and Frederic Robert-Nicoud
      Tech clusters like Silicon Valley play a central role for modern innovation, business competitiveness, and economic performance. This paper reviews what constitutes a tech cluster, how they function internally, and the degree to which policy makers can purposefully... View Details
      Keywords: Clusters; Agglomeration; Innovation; Industry Clusters; Innovation and Invention; Entrepreneurship; Patents
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      Kerr, William R., and Frederic Robert-Nicoud. "Tech Clusters." Journal of Economic Perspectives 34, no. 3 (Summer 2020): 50–76.
      • May 2020
      • Article

      Inventor Gender and the Direction of Invention

      By: Rembrand Koning, Sampsa Samila and John-Paul Ferguson
      We study whether increasing the share of female inventors leads to more biomedical inventions that focus on the needs of women. After accounting for detailed disease-technology, disease-year, and technology-year fixed effects, we find that a 10 percentage point... View Details
      Keywords: Innovation and Invention; Gender; Patents
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      Koning, Rembrand, Sampsa Samila, and John-Paul Ferguson. "Inventor Gender and the Direction of Invention." AEA Papers and Proceedings 110 (May 2020): 250–254.
      • 2023
      • Working Paper

      How Resilient Is Venture-Backed Innovation? Evidence from Four Decades of U.S. Patenting

      By: Sabrina T. Howell, Josh Lerner, Ramana Nanda and Richard Townsend
      Despite theoretical predictions to the contrary, corporate innovation is strongly pro-cyclical. In this paper, we compare innovation in the economy as a whole to that of firms backed by venture capital (VC), a source of capital associated with the most impactful young... View Details
      Keywords: Recessions; Venture Capital; Innovation and Invention; Patents; Business Cycles; Economic Slowdown and Stagnation
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      Howell, Sabrina T., Josh Lerner, Ramana Nanda, and Richard Townsend. "How Resilient Is Venture-Backed Innovation? Evidence from Four Decades of U.S. Patenting." Harvard Business School Working Paper, No. 20-115, May 2020. (Revised July 2023.)
      • April 2020
      • Article

      Technological Leadership (de)Concentration: Causes in Information and Communication Technology Equipment

      By: Yasin Ozcan and Shane Greenstein
      Using patent data from 1976 to 2010 as indicators of inventive activity, we determine the concentration level of where inventive ideas originate and then examine how and why those concentrations change over time. The analysis finds pervasive deconcentration in every... View Details
      Keywords: Deconcentration; Technological Innovation; Innovation Leadership; Patents; Market Entry and Exit; Telecommunications Industry
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      Ozcan, Yasin, and Shane Greenstein. "Technological Leadership (de)Concentration: Causes in Information and Communication Technology Equipment." Industrial and Corporate Change 29, no. 2 (April 2020): 241–263. (Winner of the Industry Studies Association 2021 Ralph Gomory Award for Best Paper.)
      • Article

      Patent Protection Should Take a Backseat in a Crisis

      By: Scott Duke Kominers
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      Kominers, Scott Duke. "Patent Protection Should Take a Backseat in a Crisis." Bloomberg Opinion (March 26, 2020).
      • March 2020
      • Article

      Do Managers Matter? A Natural Experiment from 42 R&D Labs in India

      By: Prithwiraj Choudhury, Tarun Khanna and Christos A. Makridis
      We exploit plausibly exogenous variation in the staggered entry of new managers into India’s 42 public R&D labs between 1994 and 2006 to study how alignment between the CEO and middle-level managers affect research productivity. We show that the introduction of new lab... View Details
      Keywords: Incentives; Innovation; Productivity; Management; Alignment; Research and Development; Innovation and Invention; Performance Productivity; India
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      Choudhury, Prithwiraj, Tarun Khanna, and Christos A. Makridis. "Do Managers Matter? A Natural Experiment from 42 R&D Labs in India." Journal of Law, Economics & Organization 36, no. 1 (March 2020): 47–83.
      • Article

      What We Learned from Reading Jeff Bezos' Patents

      By: Tricia Gregg and Boris Groysberg
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      Gregg, Tricia, and Boris Groysberg. "What We Learned from Reading Jeff Bezos' Patents." Harvard Business School Working Knowledge (February 6, 2020).
      • January 2020
      • Case

      The Origins of Bell Labs

      By: Tom Nicholas and John Masko
      In 1947, scientists at Bell Labs invented the transistor—a tiny signal amplifier that would go on to become the fundamental building block of the digital age. But, confounding most traditional economic assumptions, it was not a vigorous startup that made this momentous... View Details
      Keywords: Business History; Innovation Leadership; Technological Innovation; Patents; Monopoly; Organizational Structure; Competitive Strategy; Telecommunications Industry; Boston; Massachusetts; New York (city, NY)
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      Nicholas, Tom, and John Masko. "The Origins of Bell Labs." Harvard Business School Case 820-081, January 2020.
      • December 2019
      • Article

      Patent Trolls: Evidence from Targeted Firms

      By: Lauren Cohen, Umit Gurun and Scott Duke Kominers
      We provide the first large-sample evidence on the behavior and impact of nonpracticing entities (NPEs) in the intellectual-property space. We find that, on average, NPEs appear to behave as opportunistic “patent trolls.” NPEs sue cash-rich firms and target cash in... View Details
      Keywords: Patent Trolls; Innovation; Patents; Lawsuits and Litigation; Ethics; Innovation and Invention
      Citation
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      Cohen, Lauren, Umit Gurun, and Scott Duke Kominers. "Patent Trolls: Evidence from Targeted Firms." Management Science 65, no. 12 (December 2019): 5461–5486. (Cited in the United States Federal Trade Commission Report on Patent Assertion Entities, 2016.)
      • 2020
      • Working Paper

      Tech Clusters

      By: William R. Kerr and Frederic Robert-Nicoud
      Tech clusters like Silicon Valley play a central role for modern innovation, business competitiveness, and economic performance. This paper reviews what constitutes a tech cluster, how they function internally, and the degree to which policy makers can purposefully... View Details
      Keywords: Clusters; Agglomeration; Innovation; Industry Clusters; Innovation and Invention; Entrepreneurship; Patents
      Citation
      SSRN
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      Kerr, William R., and Frederic Robert-Nicoud. "Tech Clusters." Harvard Business School Working Paper, No. 20-063, November 2019. (Revised June 2020.)
      • June 2019
      • Teaching Note

      Zebra Medical Vision

      By: Shane Greenstein and Sarah Gulick
      Teaching note is meant to accompany Zebra Medical Vision case, which offers a look at a company’s decisions as a small startup competing with other startups and major technology companies. It also demonstrates the challenges faced by a machine learning company working... View Details
      Keywords: Business Startups; Science-Based Business; Applications and Software; Patents; Cross-Cultural and Cross-Border Issues; Health Care and Treatment; Health Industry; Medical Devices and Supplies Industry; Technology Industry; Israel
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      Greenstein, Shane, and Sarah Gulick. "Zebra Medical Vision." Harvard Business School Teaching Note 619-053, June 2019.
      • June 21, 2019
      • Article

      Government-Funded Research Increasingly Fuels Innovation

      By: Lee Fleming, Hillary Greene, Guan-Cheng Li, Matt Marx and Dennis Yao
      Keywords: Innovation; R&D; Patents
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      Fleming, Lee, Hillary Greene, Guan-Cheng Li, Matt Marx, and Dennis Yao. "Government-Funded Research Increasingly Fuels Innovation." Science 364, no. 6646 (June 21, 2019): 1139–1141.
      • 2021
      • Working Paper

      Who Do We Invent for? Patents by Women Focus More on Women's Health, but Few Women Get to Invent

      By: Rembrand Koning, Sampsa Samila and John-Paul Ferguson
      Has the increase in female medical researchers led to more medical advances for women? In this paper, we investigate if the gender of inventors shapes their types of inventions. Using data on the universe of U.S. biomedical patents, we find that patents with women... View Details
      Keywords: Innovation; Biomedical Research; Innovation and Invention; Diversity; Gender; Research; Health; United States
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      Koning, Rembrand, Sampsa Samila, and John-Paul Ferguson. "Who Do We Invent for? Patents by Women Focus More on Women's Health, but Few Women Get to Invent." Working Paper. (Harvard Business School Working Paper, No. 19-124, June 2019; SSRN Working Paper Series, No. 3401889, June 2019.)
      • March 2019 (Revised May 2019)
      • Case

      Fetchr: A New Way of Last Mile Delivery

      By: V.G. Narayanan and Eren Kuzucu
      By mid-2016, five years of aggressive growth had transformed Fetchr from a small logistics startup to a 1,000-employee, full-fledged last-mile delivery company operating across four countries in the Middle East and North Africa (MENA). Already beneficiaries of the... View Details
      Keywords: Startup; Decision; Financial Strategy; UAE; KSA; MENA; Cost Accounting; Business Model; Business Startups; Transformation; Cost Management; Strategy; Disruptive Innovation; Technological Innovation; Growth and Development Strategy; Growth Management; Logistics; Service Delivery; Supply Chain Management; Performance Evaluation; Mathematical Methods; Mobile and Wireless Technology; Transportation Networks; Middle East; United Arab Emirates; Dubai; Bahrain; Egypt; Saudi Arabia; North Africa
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      Narayanan, V.G., and Eren Kuzucu. "Fetchr: A New Way of Last Mile Delivery." Harvard Business School Case 119-018, March 2019. (Revised May 2019.)
      • January 2019 (Revised May 2019)
      • Case

      When Trolls Attack: Carbonite vs. Oasis Research

      By: Lauren H. Cohen, Umit G. Gurun, Scott Duke Kominers and Sarah Mehta
      This case, set in October 2017, follows Danielle Sheer, general counsel for Carbonite, as she defends the company against claims of patent infringement. It provides a broad overview of the U.S. patent system and explores the impact that non-practicing entities... View Details
      Keywords: Patent Infringement Litigation; Non-practicing Entities; Patent Trolls; Innovation and Invention; Intellectual Property; Patents; Laws and Statutes; Lawsuits and Litigation; Legal Liability; Computer Industry; Technology Industry; Boston
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      Cohen, Lauren H., Umit G. Gurun, Scott Duke Kominers, and Sarah Mehta. "When Trolls Attack: Carbonite vs. Oasis Research." Harvard Business School Case 219-001, January 2019. (Revised May 2019.)
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