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Publications

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      • 2025
      • Working Paper

      HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances

      By: Amar Bhidé, Srikant M. Datar and Katherine Stebbins
      This case history describes how a diverse cast of characters, including public health organizations, research laboratories, for-profit healthcare companies, activists, and regulators, rolled back the outbreak of HIV/AIDS in just fifteen years. Moreover, as the case... View Details
      Keywords: Health Care and Treatment; Technological Innovation; Innovation Strategy; Technology Adoption; Collaborative Innovation and Invention; Innovation and Invention; Governing Rules, Regulations, and Reforms
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      Bhidé, Amar, Srikant M. Datar, and Katherine Stebbins. "HIV Tests and AIDS Treatments—Containing a Fearsome Pandemic: Case Histories of Transformational Advances." Harvard Business School Working Paper, No. 20-007, July 2019. (Revised January 2025.)
      • March 2019 (Revised April 2021)
      • Case

      The DivaCup: Navigating Distribution and Growth

      By: Ayelet Israeli
      When the mother-daughter founders of DivaCup set out with a mission to disrupt the menstrual care industry with an innovative product form, they initially struggled to gain legitimacy and convince retailers to carry their unique product. Fifteen years later, the... View Details
      Keywords: Female; Female Ceo; Female Entrepreneur; Female Protagonist; Health & Wellness; Healthcare; Price Policies; Minimum Advertised Price; Differentiation; Positioning; Growth; Health; Health Care and Treatment; Price; Disruption; Distribution; Distribution Channels; Competitive Strategy; Competition; Growth Management; Mission and Purpose; Product Development; Product Marketing; Product Launch; Product Positioning; Advertising; Business Startups; Internet and the Web; Entrepreneurship; Social Entrepreneurship; Social Issues; Social Enterprise; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Canada; United States; United Kingdom
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      Israeli, Ayelet. "The DivaCup: Navigating Distribution and Growth." Harvard Business School Case 519-055, March 2019. (Revised April 2021.)
      • 2019
      • Working Paper

      Biometric Monitoring, Service Delivery and Misreporting: Evidence from Healthcare in India

      By: Thomas Bossuroy, Clara Delavallade and Vincent Pons
      Developing countries increasingly use biometric identification technology in hopes of improving the reliability of administrative information and delivering social services more efficiently. This paper exploits the random placement of biometric tracking devices in... View Details
      Keywords: Biometric Technology; Health Care and Treatment; Technological Innovation; Analytics and Data Science; Quality; Performance Improvement; India
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      Bossuroy, Thomas, Clara Delavallade, and Vincent Pons. "Biometric Monitoring, Service Delivery and Misreporting: Evidence from Healthcare in India." NBER Working Paper Series, No. 26388, October 2019. (Revise and resubmit requested, Review of Economics and Statistics.)
      • March 2019
      • Case

      DayTwo: Going to Market with Gut Microbiome

      By: Ayelet Israeli and David Lane
      DayTwo is a young Israeli startup that applies research on the gut microbiome and machine learning algorithms to deliver personalized nutritional recommendations to its users in order to minimize blood sugar spikes after meals. After a first year of trial rollout in... View Details
      Keywords: Start-up Growth; Startup; Positioning; Targeting; Go To Market Strategy; B2B2C; B2B Vs. B2C; Health & Wellness; AI; Machine Learning; Female Ceo; Female Protagonist; Science-based; Science And Technology Studies; Ecommerce; Applications; DTC; Direct To Consumer Marketing; US Health Care; "USA,"; Innovation; Pricing; Business Growth; Segmentation; Distribution Channels; Growth and Development Strategy; Business Startups; Science-Based Business; Health; Innovation and Invention; Marketing; Information Technology; Business Growth and Maturation; E-commerce; Applications and Software; Technology Industry; Technology Industry; Technology Industry; Technology Industry; Technology Industry; Israel; United States
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      Israeli, Ayelet, and David Lane. "DayTwo: Going to Market with Gut Microbiome." Harvard Business School Case 519-010, March 2019.
      • February 2019 (Revised August 2019)
      • Case

      Maccabitech: The Promise of Israel's Healthcare Data

      By: Scott Duke Kominers and Carin-Isabel Knoop
      Dr. Varda Shalev bridges technology and medicine through Maccabitech, a "research and innovation wing" of Israel's Maccabi Healthcare Services (MHS) that partners with research institutions, pharmaceutical companies, and startups. Shalev hopes to scale Maccabitech's... View Details
      Keywords: Big Data; Healthcare; Analytics and Data Science; Digital Platforms; Health Care and Treatment; Innovation and Invention; Research; Entrepreneurship; Risk Management; Israel
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      Kominers, Scott Duke, and Carin-Isabel Knoop. "Maccabitech: The Promise of Israel's Healthcare Data." Harvard Business School Case 819-032, February 2019. (Revised August 2019.)
      • December 2018
      • Case

      Corporate Transformation at Merck KGaA, Darmstadt, Germany

      By: Joseph B. Fuller, Amy C. Edmondson, Daniela Beyersdorfer and Tonia Labruyere
      When Stefan Oschmann became CEO and chairman of the executive board of Merck KGaA, Darmstadt, Germany, in 2016, the company had started its transformation from a mid-tier traditional German industry player to a global modern science and technology player. The... View Details
      Keywords: Corporate Governance With Family Ownership; Transformation; Change Management; Restructuring; Corporate Governance; Family Ownership
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      Fuller, Joseph B., Amy C. Edmondson, Daniela Beyersdorfer, and Tonia Labruyere. "Corporate Transformation at Merck KGaA, Darmstadt, Germany." Harvard Business School Case 319-072, December 2018.
      • October 2018
      • Case

      Fundraising at St. Camillus Hospital

      By: Srikant M. Datar and Caitlin N. Bowler
      St. Camillus is a fictional non-profit hospital in rural Maine facing a serious budget deficit. As Director of Marketing, Victoria Stern is building a team to modernize the hospital fundraising efforts. An interview with a promising candidate, who is also a digital... View Details
      Keywords: Data Analysis; Data Privacy; Data Governance; Non-profit; Health Care; Fundraising; Data Security; Analytics and Data Science; Safety; Governance; Ethics; Health Care and Treatment; Cybersecurity
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      Datar, Srikant M., and Caitlin N. Bowler. "Fundraising at St. Camillus Hospital." Harvard Business School Case 119-027, October 2018.
      • February 2018
      • Case

      Health Savings Accounts: Enabling Consumer Participation

      By: Regina E. Herzlinger and James Wallace
      Health savings accounts (HSAs), a creation of the 2003 Medicare Modernization Act, had become an integral part of the drive toward consumer-driven health care. Coupled with high-deductible health plans, HSAs allowed consumers to directly control a significant part of... View Details
      Keywords: Health Care; Healthcare Costs; Health Insurance; Health Care and Treatment; Cost; Insurance; Innovation and Invention; Health Industry; United States
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      Herzlinger, Regina E., and James Wallace. "Health Savings Accounts: Enabling Consumer Participation." Harvard Business School Case 318-110, February 2018.
      • September 2017 (Revised February 2023)
      • Case

      Intermountain Healthcare: Pursuing Precision Medicine

      By: Richard G. Hamermesh, Kathy E. Giusti, Robert S. Huckman and Julia Kelley
      Headquartered in Salt Lake City, Intermountain Healthcare operates 23 hospitals and hundreds of clinics in Utah and Idaho and provides insurance to approximately 850,000 patients through its insurance arm, SelectHealth. In 2013, Intermountain, known for its commitment... View Details
      Keywords: Precision Medicine; Healthcare; Innovation; Cancer; Cancer Research; Health Care; Technology; Health Care and Treatment; Innovation Leadership; Disruptive Innovation; Entrepreneurship; Decision Choices and Conditions; Health Industry; Insurance Industry; Utah; United States; North America
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      Hamermesh, Richard G., Kathy E. Giusti, Robert S. Huckman, and Julia Kelley. "Intermountain Healthcare: Pursuing Precision Medicine." Harvard Business School Case 818-018, September 2017. (Revised February 2023.)
      • August 2017
      • Case

      RoboTech: Storming into the U.S. Market

      By: Christopher A. Bartlett, Rachel Gordon and John J. Lafkas
      This case describes the challenges facing the CEO of a small, Singapore-based industrial robotics company that decides to diversify away from its core industrial robot business by leveraging its expertise into the medical-devices industry. It launches an innovative... View Details
      Keywords: Market Entry and Exit; Diversification; Product Launch; Competitive Strategy; Globalized Firms and Management; Technology Industry; Technology Industry; Singapore; United States
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      Bartlett, Christopher A., Rachel Gordon, and John J. Lafkas. "RoboTech: Storming into the U.S. Market." Harvard Business School Brief Case 918-501, August 2017.
      • April 2017
      • Case

      Imprimis (A)

      By: Ramon Casadesus-Masanell, Karen Elterman and Marc Appel
      This case examines the strategic choices and evolving business model of Imprimis Pharmaceuticals from the perspective of CEO Mark Baum. The (A) case provides a brief history of the company and of the compounding business, outlining the challenges faced by Imprimis in... View Details
      Keywords: Strategy; Healthcare; Drug Compounding; Pharmaceuticals; Compounding; Drug Development; Decision-making; Mark Baum; Imprimis; Small Business; Decisions; Cost vs Benefits; Business Strategy; Business Model; Decision Choices and Conditions; Pharmaceutical Industry; United States
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      Casadesus-Masanell, Ramon, Karen Elterman, and Marc Appel. "Imprimis (A)." Harvard Business School Case 717-426, April 2017.
      • Article

      One Obstacle to Curing Cancer: Patient Data Isn't Shared

      By: Richard G. Hamermesh and Kathy Giusti
      Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details
      Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States
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      Hamermesh, Richard G., and Kathy Giusti. "One Obstacle to Curing Cancer: Patient Data Isn't Shared." Harvard Business Review (website) (November 28, 2016).
      • November 2016 (Revised November 2016)
      • Case

      Radial Analytics Probes Post-Acute Care

      By: Richard G. Hamermesh and Olivia Hull
      Thaddeus Fulford-Jones and Eric Weiss, founders of healthcare technology startup Radial Analytics, have been busy developing a software program designed to save hospitals money and improve patient outcomes by producing customized care plans for patients leaving the... View Details
      Keywords: Electronic Medical Records; Electronic Health Records; Data Science; Entrepreneurship; Health Care and Treatment; Business Model; Business Startups; Innovation and Invention; Growth Management; Marketing Strategy; Product Launch; Product Positioning; Science-Based Business; Business Strategy; Technology Industry; Technology Industry; Cambridge; Massachusetts
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      Hamermesh, Richard G., and Olivia Hull. "Radial Analytics Probes Post-Acute Care." Harvard Business School Case 817-029, November 2016. (Revised November 2016.)
      • October 2016 (Revised November 2016)
      • Case

      Innovating Beyond Ochsner

      By: Richard G. Hamermesh and Olivia Hull
      The Ochsner Health System has developed a proprietary software tool designed to treat hypertension. Built into the system’s electronic medical records, the Hypertension Digital Medicine program allows patients to record their blood pressure at home and share readings... View Details
      Keywords: Electronic Medical Records; Telemedicine; Hypertension; High Blood Pressure; Chronic Disease; Entrepreneurship; Health Disorders; Business Model; Business Startups; Innovation and Invention; Growth Management; Marketing Strategy; Product Launch; Product Positioning; Science-Based Business; Business Strategy; Technology Industry; Technology Industry; New Orleans; Louisiana
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      Hamermesh, Richard G., and Olivia Hull. "Innovating Beyond Ochsner." Harvard Business School Case 817-028, October 2016. (Revised November 2016.)
      • May 25, 2016
      • Comment

      How Consumers and Businesses are Reshaping Public Health

      By: John A. Quelch
      Healthcare and education are two issues in which citizens around the world, rich and poor, are passionately interested. It has long been appreciated that the way that a society treats its youngest and oldest members says much about its moral maturity. Economic... View Details
      Keywords: Healthcare; Consumer Power; Innovation In Healthcare Delivery; Mobile Healthcare; Transition; Transformation; Trends; Customer Satisfaction; Customer Value and Value Chain; Health Care and Treatment; Information; Collaborative Innovation and Invention; Independent Innovation and Invention; Innovation and Management; Innovation Leadership; Management; Marketing; Markets; Planning; Problems and Challenges; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; Green Technology Industry; South America; North and Central America; Middle East; Europe; Asia
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      Quelch, John A. "How Consumers and Businesses are Reshaping Public Health." Harvard Business School Working Knowledge (May 25, 2016).
      • Article

      Value-based Healthcare: Implications for Thyroid Cancer

      By: A.K. Ying, T.W. Feeley and M. E. Porter
      Today's delivery of care to thyroid cancer patients is complex, and costly, with uneven outcomes that can be improved. The incidence of thyroid cancer is rising and requires coordinated, multidisciplinary care with high volume centers that is not always available in... View Details
      Keywords: Bundled Reimbursement; Healthcare Reform; Integrated Practice Units; Outcomes; Patient-reported Outcomes; Thyroid Cancer; Health Care and Treatment; Cost; Information Technology; Value
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      Ying, A.K., T.W. Feeley, and M. E. Porter. "Value-based Healthcare: Implications for Thyroid Cancer." International Journal of Endocrine Oncology 3, no. 2 (May 2016): 115–129. (e-Pub 4/2016.)
      • September 2015 (Revised February 2023)
      • Case

      Emdeon's Acquisition of Change Healthcare: Innovating Transparency Solutions for Health Care Consumers

      By: Regina E. Herzlinger, Jeet Guram and Aanchal Raj
      Case describes acquisition of Change Healthcare, which provides health care cost and quality information, by Emdeon, a health information exchange, and discusses health care transparency. Emdeon is a billion-dollar company that has grown through acquisitions; at its... View Details
      Keywords: Healthcare; Healthcare Industry; Healthcare Innovation; Health Care and Treatment; Acquisition; Integration; Analytics and Data Science; Mergers and Acquisitions; Competitive Strategy; Health Industry; United States
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      Herzlinger, Regina E., Jeet Guram, and Aanchal Raj. "Emdeon's Acquisition of Change Healthcare: Innovating Transparency Solutions for Health Care Consumers." Harvard Business School Case 316-026, September 2015. (Revised February 2023.)
      • May 2015 (Revised September 2015)
      • Case

      Philips Healthcare: Marketing the HealthSuite Digital Platform

      By: John A. Quelch and Margaret L. Rodriguez
      In June 2014, leading healthcare and consumer technology company, Royal Philips ("Philips"), announced its HealthSuite Digital Platform to house healthcare data and enable applications used by physicians and patients. Philips had strong equity in the healthcare... View Details
      Keywords: Health; Healthcare; Digital; Platform; Ecosystem; Health Care and Treatment; Technological Innovation; Information Technology; Product Development; Applications and Software; Digital Platforms; Health Industry; Medical Devices and Supplies Industry; Netherlands; United States
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      Quelch, John A., and Margaret L. Rodriguez. "Philips Healthcare: Marketing the HealthSuite Digital Platform." Harvard Business School Case 515-052, May 2015. (Revised September 2015.)
      • April 2015
      • Case

      Carolinas HealthCare System: Consumer Analytics

      By: John A. Quelch and Margaret L. Rodriguez
      In 2014, Dr. Michael Dulin, chief clinical officer for analytics and outcomes research and head of the Dickson Advanced Analytics (DA2) group at Carolinas HealthCare System (CHS), successfully unified all analytics talent and resources into one group over a three year... View Details
      Keywords: Consumer Segmentation; Big Data; Management Information Systems; Hospital Management; Health Care and Treatment; Marketing; Segmentation; Analytics and Data Science; Information Management; Information Technology; Health; Health Industry; United States
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      Quelch, John A., and Margaret L. Rodriguez. "Carolinas HealthCare System: Consumer Analytics." Harvard Business School Case 515-060, April 2015.
      • March 2015 (Revised January 2024)
      • Case

      CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies

      By: Regina E. Herzlinger and Andrew Otazo
      Duke Rohlen (HBS MBA ’01) hoped to win over a prominent venture capital investor for Series B financing of his firm CVI that was creating a drug-eluting balloon (DES) to treat peripheral arterial disease. As a second-mover, Duke felt he was more likely to acquire... View Details
      Keywords: CV Ingenuity; CVI; Drug Eluting Balloon; DEB; Drug Eluting Stent; Angioplasty Balloon; FoxHollow; Medical Device; Medical Device Startup; Premarket Approval; PMA; Lutonix; Stellarex; LEVANT; ILLUMENATE; Clinical Trials; Peripheral Arterial Disease; PAD; Healthcare Startups; Covidien; Health Care and Treatment; Health Testing and Trials; Business Startups; Commercialization; Health Industry; Medical Devices and Supplies Industry; United States; Europe
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      Herzlinger, Regina E., and Andrew Otazo. "CV Ingenuity (A): How to Evaluate the Commercial Viability of New Health Care Technologies." Harvard Business School Case 315-045, March 2015. (Revised January 2024.)
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