Cancer Research - Publications - Faculty & Research

18 Dec 2018
First Look

New Research and Ideas, December 18, 2018

the threshold for research and development (R&D) investment in an economically viable product. Further, the small size of patient populations for orphan drugs, together with the increasing prevalence of biologics among orphan drugs,... View Details

Keywords: Dina Gerdeman

12 Dec 2017
First Look

New Research and Ideas, December 12, 2017

protagonist on the precipice of a great crisis: Shackleton marooned on an Antarctic ice floe; Lincoln on the verge of seeing the Union collapse; escaped slave Douglass facing possible capture; Bonhoeffer agonizing over how to counter absolute evil with faith; Carson... View Details

Keywords: Sean Silverthorne

19 Sep 2016
Research & Ideas

Why Isn't Business Research More Relevant to Business Practitioners?

news hook, although it may not be as obvious as, say, a breakthrough in cancer research. Remember the aforementioned research by Bazerman et al., which explained the unconscious biases that cause auditors to... View Details

Keywords: by Carmen Nobel; Education

07 Nov 2017
First Look

New Research and Ideas: November 7, 2017

https://www.hbs.edu/faculty/Pages/item.aspx?num=53441 forthcoming Operations Research Letters Orienteering for Electioneering By: Kallenbach, Jonah, Robert Kleinberg, and Scott Duke Kominers Abstract—In this paper, we introduce a... View Details

Keywords: Carmen Nobel

September 2017 (Revised July 2023)
Case

Adaptive Platform Trials: The Clinical Trial of the Future?

By: Ariel D. Stern and Sarah Mehta

In July 2017, Dr. Brian M. Alexander, president and CEO of the AGILE Research Foundation, was preparing to launch a new type of clinical trial—an adaptive platform trial—to study potential therapies for glioblastoma (GBM), an aggressive form of brain cancer.... View Details

Keywords: Clinical Trials; Cancer; Adaptive Platform Trials; Platform Trials; Adaptive Trials; Glioblastoma; Health; Health Care and Treatment; Health Testing and Trials; Business Strategy; Innovation Strategy; Health Industry; United States

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01 Dec 2014
News

Research Brief: The Power of Could

Say you’re in a bind, a tough one. You’ve got cancer and your only hope is chemo—the problem is, it’s wildly expensive and you’re flat broke. Do you follow your moral compass, even if it means dying? Or do you leverage your knack for... View Details

16 Jul 2019
News

The Making of a Movement

proceeds from research specific to sarcoma—the disease Jen fought—to all rare cancers. The significance of that selfless shift was seismic. By loosening the link between Cycle for Survival and their own circumstances, the Linns gave... View Details

Keywords: Greg Forbes Siegman; cancer

29 Aug 2017
First Look

First Look at New Research and Ideas, August 29

people imagining imminent death. Study 1 revealed that blog posts of near-death patients with cancer and amyotrophic lateral sclerosis were more positive and less negative than the simulated blog posts of nonpatients—and also that the... View Details

Keywords: Sean Silverthorne

10 Oct 2017
First Look

First Look at New Research and Ideas, October 10, 2017

therapies for a given disease and promised a number of efficiency improvements. They also used statistical techniques to allow more patients access to promising therapies. As such, they had the potential to fundamentally change the clinical View Details

Keywords: Sean Silverthorne

Web

Faculty & Researchers - Managing the Future of Work

Faculty & Researchers Faculty & Researchers Project Co-Chairs Joseph B. Fuller Professor of Management Practice Joseph Fuller is a Professor of Management Practice at the Harvard Business School, the... View Details

09 Jan 2018
First Look

First Look at New Research and Ideas, January 9, 2018

type of entrepreneurial population studied (e.g., Main Street vs. those backed by venture capital) to identify interesting and irreducible parts of this heterogeneity, while also identifying places where we anticipate future large-scale View Details

Keywords: Sean Silverthorne

17 Aug 2011
News

Breath of Life

Green: Participating in the stem-cell revolution. Courtesy David Green It was the kind of medical miracle that experts say will one day be commonplace. In June, an artificial trachea (windpipe), infused with a tracheal cancer patient’s... View Details

Keywords: stem cell research; Ambulatory Health Care Services; Health, Social Assistance

Article

One Obstacle to Curing Cancer: Patient Data Isn't Shared

By: Richard G. Hamermesh and Kathy Giusti

Precision Medicine requires large datasets to identify the mutations that lead to various cancers. Currently, genomic information is hoarded in fragmented silos within numerous academic medical centers, pharmaceutical companies, and some disease-based foundations. For... View Details

Keywords: Healthcare; Technological And Scientific Innovation; Cancer Care In The U.S.; Cancer Treatment; Precision Medicine; Personalized Medicine; Data Sharing; Technological Innovation; Analytics and Data Science; Health Disorders; Medical Specialties; Research and Development; Customization and Personalization; Health Industry; United States

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May–June 2018
Article

Data Uncertainty in Markov Chains: Application to Cost-Effectiveness Analyses of Medical Innovations

By: Joel Goh, Mohsen Bayati, Stefanos A. Zenios, Sundeep Singh and David Moore

Cost-effectiveness studies of medical innovations often suffer from data inadequacy. When Markov chains are used as a modeling framework for such studies, this data inadequacy can manifest itself as imprecision in the elements of the transition matrix. In this paper,... View Details

Keywords: Markov Chains; Cost Effectiveness; Medical Innovations; Colorectal Cancer; Health Care and Treatment; Cost vs Benefits; Innovation and Invention; Mathematical Methods; Health Industry

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October 2013
Case

FasterCures: Removing Barriers to Treatments

By: Richard G. Hamermesh and James Weber

In mid-2013, as FasterCures celebrated its 10th anniversary as a center of the Milken Institute, Executive Director Margaret Anderson thought about what the organization should do to ensure it had even more impact in its next 10 years. FasterCures was a non-profit... View Details

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July 2021
Supplement

Adaptive Platform Trials: The Clinical Trial of the Future? (C)

By: Ariel D. Stern and Sarah Mehta

This (C) case provides an update on the work of the Global Coalition for Adaptive Research (GCAR) and also illustrates how adaptive platform trials can nimbly respond to a global pandemic. View Details

Keywords: Clinical Trials; Drug Trials; Drug Testing; Cancer Trials; Glioblastoma; Platform Trials; Adaptive Trials; Adaptive Platform Trials; Health Testing and Trials; Health Care and Treatment; Business Strategy; Health Industry; United States

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25 Apr 2014
Video

Kathryn Giusti - Making A Difference

February 1994 (Revised May 1999)
Case

Manville Corp. Fiber Glass Group (C)

By: Lynn S. Paine and Sarah Gant

Manville Corp.'s senior managers are surprised when Japanese government officials advise them not to go forward with their plan to add a cancer warning label to diatomaceous earth (DE) products sold in Japan. The International Agency for Research on Cancer has ruled... View Details

Keywords: Management Teams; Ethics; Conflict of Interests; Health; Safety; Cross-Cultural and Cross-Border Issues; Policy; Japan

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December 2003
Case

Manville Corporation Fiber Glass Group (C) (Abridged)

By: Lynn S. Paine

Manville Corp.'s senior managers are surprised when Japanese government officials advise them not to go forward with their plan to add a cancer warning label to diatomaceous earth (DE) products sold in Japan. The International Agency for Research on Cancer has ruled... View Details