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  • March 2023 (Revised March 2023)
  • Case

Roche: Innovation and Access to Healthcare

By: George Serafeim, Susanna Gallani and Benjamin Maletta
In May 2022, Roche Group, one of the largest healthcare companies in the world, hosted its first investor event focused exclusively on its efforts to impact access to healthcare. While Roche had recently set an ambitious goal to double the number of patients that had... View Details
Keywords: ESG (Environmental, Social, Governance) Performance; Sustainable Finance; Growth Strategy And Execution; Sustainability Targets; Impact Evaluation; Healthcare Access; Healthcare Innovation; Healthcare Systems; Healthcare Operations; Finance; Strategy; Health Testing and Trials; Health Care and Treatment; Growth Management; Measurement and Metrics; Innovation Strategy; Corporate Social Responsibility and Impact; Health Industry; Pharmaceutical Industry; Switzerland; North America; Europe; Asia; Latin America; Africa
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Serafeim, George, Susanna Gallani, and Benjamin Maletta. "Roche: Innovation and Access to Healthcare." Harvard Business School Case 123-075, March 2023. (Revised March 2023.)
  • 13 Aug 2020
  • Research & Ideas

6 Ways to Support COVID-Weary Employees

and are highly work-engaged. All of this suggests a multi-pronged solution to contagious presenteeism: Remove financial incentives for it by providing paid sick leave, audit work designs for features that... View Details
Keywords: by Dina Gerdeman
  • 15 Feb 2017
  • Op-Ed

What Africa Can Teach the United States About Funding Infrastructure Projects

President Trump’s infrastructure plan and a counterproposal by Senate Democrats are rising toward the top of the national agenda. All agree that there is a pressing need to fix the collapsing bridges, potholed roads, crashing trains, and... View Details
Keywords: by John Macomber; Construction
  • 30 May 2007
  • Research & Ideas

Health Care Under a Research Microscope

formidable research and teaching talents on bringing business-focused solutions and perspectives to address these problems. Some examples: In Zambia, Nava Ashraf and several colleagues conducted field studies to determine if charging for... View Details
Keywords: by Sean Silverthorne; Health; Biotechnology
  • August 2013 (Revised November 2015)
  • Case

Prudential Financial - General Motors Pension Risk Transfer: Back to the Future?

By: Luis M. Viceira and Emily A. Chien

In November 2012, Prudential Financial and General Motors closed on a $25.1B pension risk transfer (PRT) transaction, the largest of its kind to date by an order of magnitude both in the U.S. market and globally. In exchange for an in-kind transfer of $25.1B in... View Details

Keywords: Risk Management; Asset Management; Insurance; Retirement; Financial Services Industry; Insurance Industry
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Viceira, Luis M., and Emily A. Chien. "Prudential Financial - General Motors Pension Risk Transfer: Back to the Future?" Harvard Business School Case 213-126, August 2013. (Revised November 2015.)
  • 16 Mar 2009
  • Research & Ideas

When the Internet Runs Out of IP Addresses

problem? A: IPv6 offers important benefits. In particular, if all networks ran IPv6, there would be plenty of addresses for everyone, and we'd have no further address shortage. But it's difficult to get from here to there. Right now,... View Details
Keywords: by Sean Silverthorne; Telecommunications
  • April 2009 (Revised August 2009)
  • Case

Petrobras in Ecuador (A)

By: Aldo Musacchio, Lena G. Goldberg and Ricardo Reisen de Pinho
On October 18, 2007, Ecuador's President Rafael Correa announced his intention to migrate Petrobras' existing participation contracts to exploit oil reserves in Ecuador's Blocks 18 and 31 to servicing agreements under which Petrobras would be paid a production fee and... View Details
Keywords: Metals and Minerals; Globalized Firms and Management; Corporate Governance; Government Administration; Taxation; Contracts; Negotiation Process; Negotiation Tactics; Public Ownership; Business and Government Relations; Business and Shareholder Relations; Brazil; Ecuador
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Musacchio, Aldo, Lena G. Goldberg, and Ricardo Reisen de Pinho. "Petrobras in Ecuador (A)." Harvard Business School Case 309-107, April 2009. (Revised August 2009.)
  • 2009
  • Working Paper

Consistency and Monotonicity in One-Sided Assignment Problems

By: Bettina-Elisabeth Klaus and Alexandru Nichifor
One-sided assignment problems combine important features of two well-known matching models. First, as in roommate problems, any two agents can be matched and second, as in two-sided assignment problems, the payoffs of a matching can be divided between the agents. We... View Details
Keywords: Markets
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Klaus, Bettina-Elisabeth, and Alexandru Nichifor. "Consistency and Monotonicity in One-Sided Assignment Problems." Harvard Business School Working Paper, No. 09-146, June 2009.
  • July 2011 (Revised September 2011)
  • Case

Game Time Decision for AppDirect

By: Andrei Hagiu, Laura Arjona and Emily Zhang
AppDirect is a start-up that offers small businesses software-as-a-service solutions through a business app marketplace and portal. Daniel Saks, co-founder and co-CEO, is faced with the key question of deciding distribution strategy: should AppDirect find channel... View Details
Keywords: Digital Platforms; Distribution; Applications and Software; Innovation Strategy; Entrepreneurship; Business Growth and Maturation; Competitive Strategy; Information Technology Industry; United States
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Hagiu, Andrei, Laura Arjona, and Emily Zhang. "Game Time Decision for AppDirect." Harvard Business School Case 712-410, July 2011. (Revised September 2011.)
  • May–June 2025
  • Article

Slowly Varying Regression Under Sparsity

By: Dimitris Bertsimas, Vassilis Digalakis Jr, Michael Lingzhi Li and Omar Skali Lami
We consider the problem of parameter estimation in slowly varying regression models with sparsity constraints. We formulate the problem as a mixed integer optimization problem and demonstrate that it can be reformulated exactly as a binary convex optimization problem... View Details
Keywords: Mathematical Methods; Analytics and Data Science
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Bertsimas, Dimitris, Vassilis Digalakis Jr, Michael Lingzhi Li, and Omar Skali Lami. "Slowly Varying Regression Under Sparsity." Operations Research 73, no. 3 (May–June 2025): 1581–1597.
  • December 2, 2021
  • Article

Former Best Buy CEO Hubert Joly: Empowering Workers to Create ‘Magic’

By: Hubert Joly and Adi Ignatius
Hubert Joly was behind an amazing turnaround at Best Buy. While everybody was saying he should lay people off to solve the company’s problems, Joly instead listened to the people working for him and found solutions that didn’t involve people losing their jobs.... View Details
Keywords: Purpose; Meaningful Work; Employee Empowerment; Mission and Purpose; Employees; Organizational Culture; Leadership
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Joly, Hubert, and Adi Ignatius. "Former Best Buy CEO Hubert Joly: Empowering Workers to Create ‘Magic’." Harvard Business Review (website) (December 2, 2021). (Interview with Adi Ignatius, with embedded video.)
  • 2021
  • Book

Management as a Calling: Leading Business, Serving Society

By: Andrew J. Hoffman
Business leaders have tremendous power to influence our society, how it operates, whether it is fair, and the extent to which it impacts the environment. And yet, we do not recognize or call out the responsibility that comes with that power. This book is meant to... View Details
Keywords: Business Education; Power and Influence; Corporate Social Responsibility and Impact; Social Issues; Leadership
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Hoffman, Andrew J. Management as a Calling: Leading Business, Serving Society. Stanford University Press, 2021. (Winner of the 2022 PROSE Book Award, Association of American Publishers; Winner of the 2022 Best Book Award, Social Issues in Management Division, Academy of Management; Finalist for the 2022 George R. Terry Book Award, Academy of Management. Chinese Edition: 使命管理, China Science and Technology Press, 2022.)
  • January 2021 (Revised July 2022)
  • Case

Snapp: Scaling Under Sanctions in Iran (A)

By: Meg Rithmire and Gamze Yucaoglu
The case opens in November 2019 as Eyad Alkassar and Mahmoud Fouz, co-founders of Iran’s first and leading ride-hailing platform, Snapp, find out about Apple’s and Google’s decisions to remove all Iranian apps from their respective application stores.
The case... View Details
Keywords: Sanctions; Change Management; Disruption; Volatility; Decision Choices and Conditions; Cross-Cultural and Cross-Border Issues; Government and Politics; International Relations; National Security; Risk Management; Crisis Management; Transportation Industry; Iran; Middle East
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Rithmire, Meg, and Gamze Yucaoglu. "Snapp: Scaling Under Sanctions in Iran (A)." Harvard Business School Case 721-020, January 2021. (Revised July 2022.)
  • 05 Dec 2013
  • Op-Ed

Encourage Breakthrough Health Care by Competing on Products Rather Than Patents

over the distribution of knowledge. To date, they have been far too concerned with the size of their royalties, at the expense of public utility. The fate of discoveries we all rely upon, and the intellectual property that results from... View Details
Keywords: by Richard G. Hamermesh; Biotechnology; Health
  • 07 Aug 2009
  • What Do You Think?

Why Can’t Americans Get Health Care Right?

provided excellent comparative data of the kind that we have seen all too little in the public debate on the matter. And nearly everyone admirably avoided the political rhetoric that has clouded rational thought about a truly complex... View Details
Keywords: by Jim Heskett; Health
  • October 2024 (Revised February 2025)
  • Case

Lanco Medical Group: Fostering Happiness for Growth

By: Susanna Gallani, Jenyfeer Martínez Buitrago and Katherine Sonnefeldt
This case describes how Lanco Medical Group, a fast-growing pharmaceutical distributor serving Latin America, approached the design of their employee benefits and incentives program. After learning about gaps between what leadership believed motivated employees and... View Details
Keywords: Fairness; Compensation and Benefits; Retention; Growth Management; Motivation and Incentives; Expansion; Pharmaceutical Industry; Latin America
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Gallani, Susanna, Jenyfeer Martínez Buitrago, and Katherine Sonnefeldt. "Lanco Medical Group: Fostering Happiness for Growth." Harvard Business School Case 125-062, October 2024. (Revised February 2025.)
  • 02 Jul 2009
  • Research Event

Business Summit: The Role of Social Entrepreneurship in Transforming American Public Education

like lack of political will to drive change. Yet amid these formidable barriers, a set of passionate social entrepreneurs are disrupting the status quo in education with innovative and effective approaches that are producing measurable results. These education... View Details
Keywords: Education
  • 19 Jun 2018
  • Research Event

Has Environmental Sustainability Lost its Relevance?

practitioners viable solutions. Three decades of writers asserting that win-win solutions were possible had made it all seem too easy to achieve results, when it’s not. Sustainability has become reconciled... View Details
Keywords: by Geoffrey G. Jones; Energy
  • 26 Aug 2024
  • Research & Ideas

Can AI Match Human Ingenuity in Creative Problem-Solving?

When ChatGPT and other large language models began entering the mainstream two years ago, it quickly became apparent the technology could excel at certain business functions, yet it was less clear how well artificial intelligence could handle more creative tasks. Sure,... View Details
Keywords: by Michael Blanding; Information Technology; Information; Technology
  • 2021
  • Book

We the Possibility: Harnessing Public Entrepreneurship to Solve Our Most Urgent Problems

By: Mitchell Weiss
The huge public challenges we face are daunting. At the same time, many of us have come to accept the notion that government can't do new things or solve tough challenges—it's too big and slow and bureaucratic. Not so. Entrepreneurial savvy in government is growing,... View Details
Keywords: Entrepreneurship; Public Sector; Government Administration; Government and Politics; Technological Innovation; Problems and Challenges; Innovation Leadership; Public Administration Industry; Technology Industry
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Weiss, Mitchell. We the Possibility: Harnessing Public Entrepreneurship to Solve Our Most Urgent Problems. Boston, MA: Harvard Business Review Press, 2021.
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